Adenosine deaminase prefers a distinct sugar ring conformation for binding and catalysis: Kinetic and structural studies

Biochemistry

Volumn 39, Issue 10, 2000, Pages 2581-2592

  Ford Jr , Harry ^a   Dai, Fang ^a   Mu, Lan ^a   Siddiqui, Maqbool A ^a   Nicklaus, Marc C ^a   Anderson, Lynne ^a   Marquez, Victor E ^a   Barchi Jr , Joseph J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DERIVATIVE;

ARTICLE; CATALYSIS; ENZYME BINDING; ENZYME KINETICS; ENZYME SUBSTRATE; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

ADENOSINE; ADENOSINE DEAMINASE; ANIMALS; BINDING SITES; CATALYSIS; CATTLE; ENZYME INHIBITORS; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTONS; SUBSTRATE SPECIFICITY;

ADA;

EID: 0040609327     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992112c     Document Type: Article

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