Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase

Biochemistry

Volumn 35, Issue 5, 1996, Pages 1672-1680

  Mohamedali, Khalid A ^a,c   Kurz, Linda C ^b   Rudolph, Frederick B ^a  

^a RICE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE MONOPHOSPHATE DEAMINASE; GLUTAMIC ACID; MUTANT PROTEIN;

ARTICLE; COMBINED IMMUNODEFICIENCY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME DEFICIENCY; ENZYME MECHANISM; ENZYME PURIFICATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ADENOSINE DEAMINASE; ANIMALS; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; ENZYME INHIBITORS; GLUTAMIC ACID; KINETICS; METALLOPROTEINS; MICE; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PURINE NUCLEOSIDES; RECOMBINANT PROTEINS; RIBONUCLEOSIDES; ZINC;

ADA; FELIS CATUS;

EID: 0030038183     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9514119     Document Type: Article

References (49)

1. Adler, A. J., Greenfield, N. J., & Fasman, G. D. (1973) in Methods in Enzymology (Hirs, C. H. W., & Timasheff, S. N., Eds.) Vol. 27, pp 675-735, Academic Press, New York.
2. Agarwal, R. P. (1982) Pharmacol. Ther. 17, 399-429.
3. Aronow, B., Lattier, D., Silbiger, R., Dusing, M., Hutton, J., Jones, G., Stock, J., McNeish, J., Potter, S., Witte, D., & Wiginton, D. (1989) Genes Dev. 3, 1384-1400.
4. Auld, D. S. (1988) in Methods in Enzymology (Riordan, J. F., & Vallee, B. F., Eds.) Vol. 158, pp 13-14, Academic Press, New York.
5. Bhaumik, D., Medin, J., Gathy, K., & Coleman, M. (1993) J. Biol. Chem. 268, 5464-5470.
6. Bradford, M. (1976) Anal. Biochem. 72, 248-254.
7. Caiolfa, V. R., Gill, D., & Parola, A. H. (1990) FEBS Lett. 260, 19-22.
8. Chang, Z. (1992) Ph.D. Thesis, Baylor College of Medicine, Houston, TX.
9. Chang, Z., Nygaard, R. Chinault, A. C., & Kellems, R. E. (1991) Biochemistry 30, 2273-2280.
10. Chinsky, J. M., Ramamurthy, V., Knudsen, T. B., Higley, H. R., Fanslow, W. C., Trentin, J. J., & Kellems, R. E. (1989) UCLA Symp. Mol. Cell. Biol., New Ser. 87, 255-268.
11. Chinsky, J. M., Ramamurthy, V., Fanslow, W. C., Ingolia, D. E., Blackburn, M. R., Shaffer, K. T., Higley, H. R., Trentin, J. J., Rudolph, F. B., Knudsen, T. B., & Kellems, R. E. (1990) Differentiation 42, 172-183.
12. Cleland, W. W. (1992) Biochemistry 31, 317-319.
13. Durak, I., Isik, A. C. U., Canbolat, O., Akyol, O., & Kavutcu, M. (1993) Free Radical Biol. Med. 15, 681-684.
14. Evans, B. E., & Wolfenden, R. (1973) Biochemistry 12, 392-398.
15. Frick, L., Neela, J. P., & Wolfenden, R. (1987) Bioorg. Chem. 15, 100-108.
16. Hirschhorn, R., Nicknam, M. N., Eng, F., Yang, D. R., & Borkowsky, W. (1992) J. Immunol. 149, 3107-3112.
17. Jones, W., Kurz, L. C., & Wolfenden, R. (1989) Biochemistry 28, 1242-1247.
18. Kati, W. M., & Wolfenden, R. (1989) Biochemistry 28, 7919-7927.
19. Kati, W. M., Acheson, S. A., & Wolfenden, R. (1992) Biochemistry 31, 7356-7366.
20. Kanno, H., Tani, K., Fujii, H., Iguchi-Ariga, S. M. M., Ariga, H., Kozaki, T., & Miwa, S, (1988) Jpn. J. Exp. Med. 58, 1-8.
21. Kizaki, H., Sonoki, H., Fumibiro, O., & Tomoni, S. (1973) Cell. Immunol. 82, 343-351.
22. Knudsen, T. B., Gray, M. K., Church, M. R., Blackburn, M. J., Airhart, M. J., Kellems, R. E., & Skalko, R. G. (1989) Tetralogy 40, 615-626.
23. Knudsen, T. B., Blackburn, M. R., Chinsky, J. M., Airhart, M. J., & Kellems, R. E. (1991) Biol. Reprod. 44, 171-184.
24. Kredich, N. M., & Hershfield, M. S. (1989) in The Metabolic Basis of Inherited Disease (Scriver, C. R., et al., Eds) pp 1045-1075. McGraw Hill, New York.
25. Kunkel, T. A., Roberts, J. D., & Zakour, R. A. (1987) Methods Enzymol. 154, 367-382.
26. Kurz, L. C., & Frieden, C. (1983) Biochemistry 22, 382-389.
27. Kurz, L. C., & Frieden, C. (1987) Biochemistry 26, 8450-8457.
28. Kurz, L. C., LaZard, D., & Frieden, C. (1985) Biochemistry 24, 1342-1347.
29. Kurz, L. C., Moix, L., Riley, M. C., & Frieden, C. (1992) Biochemistry 31, 39-48.
30. Laemmli, U. K. (1970) Nature 227, 680-685.
31. Mohamedali, K. A., Guicherit, O. M., Kellems, R. E., & Rudolph, F. B. (1993) J. Biol. Chem. 268, 23728-23733.
32. Murray, J. L., Loftin, K. C., Munn, C. G., Reuben, L. M., Mansell, P. W. A., & Hersh, E. M. (1985) Blood 65, 1318-1324.
33. Orozco, M., Lluis, C., Mallol, J., Canela, E. I., & Franco, R. (1989) Quant. Struct.-Act. Relat. 8, 109-114.
34. Orozco, M., Canela, E. I., & Franco, R. (1990a) Eur. J. Biochem. 188, 155-163.
35. Orozco, M., Lluis, C., Mallol, J., Canela, E. I., & Franco, R. (1990b) J. Pharmacol. Sci. 79, 133-137.
36. Parkman, R., Gelfand E. W., Rosen, F. S., Sanderson, A., & Hirschhorn R. N. (1975) N. Engl. J. Med. 292, 714-719.
37. Radzicka, A., & Wolfenden, R. (1995) Science 267, 90-93.
38. Renouf, J. A., Wood, A., Frazier, I. H., Thong, Y. H., & Chalmers, A. H. (1989) Clin. Chem. 35, 1478-1481.
39. Sanger, F., Dicklen, S., & Coulson, A. R. (1977) Proc. Natl. Acad. Sci U.S.A. 74, 5463-5467.
40. Senba, E., Daddona, P. E., & Nagy, J. I. (1987) J. Comp. Neurol. 255, 217-230.
41. Sharff, A. J., Wilson, D. K., Chang, Z., & Quiocho, F. A. (1992) J. Mol. Biol. 226, 917-921.
42. Smits, P. Boekema, P., De Abreu, R., Thein, T., & van't Laar, A. (1987) J. Cardiovasc. Pharmacol. 10, 136-143.
43. Weiss, P. M., Cook, P. F., Hermes, J. D., & Cleleand, W. W. (1987) Biochemistry 26, 7378-7384.
44. Wilson, D. K., & Quiocho, F. A. (1993) Biochemistry 32, 1689-1693.
45. Wilson, D. K., & Quiocho, F. A. (1994) Struct. Biol. 1, 691-694.
46. Wilson, D. K., Rudolph, F. B., & Quiocho, F. A. (1991) Science 252, 1278-1284.
47. Wolfenden, R., Kaufman, J., & Macon, J. B. (1969) Biochemistry 8, 2412-2415.
48. Yeuns, C.-Y., Riser, M. E., Kellems, R. E., & Siciliano, M. J. (1983) J. Biol. Chem. 258, 8330-8337.
49. Zielke, C. L., & Suelter, C. H. (1971) in The Enzymes (Boyer, P. D., Ed.) Vol. 4, pp 47-78, Academic Press, New York.