Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: Substitution of histidine 238 does not impede hydroxylate formation

Biochemistry

Volumn 35, Issue 47, 1996, Pages 15019-15028

  Sideraki, Vera ^a   Wilson, David K ^b   Kurz, Linda C ^c   Quiocho, Florante A ^b   Rudolph, Frederick B ^a  

^a RICE UNIVERSITY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; ALANINE; AMINO ACID; ARGININE; GLUTAMIC ACID; HISTIDINE; HYDROGEN; NEBULARINE; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CRYSTALLOGRAPHY; ENZYME ACTIVITY; FLUORESCENCE SPECTROSCOPY; HYDROGEN BOND; IMMUNOBLOTTING; MOUSE; MUTANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

ADENOSINE DEAMINASE; ANIMALS; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; HISTIDINE; HYDROGEN-ION CONCENTRATION; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PURINES; SPECTRUM ANALYSIS; SUBSTRATE SPECIFICITY;

FELIS CATUS; MURINAE;

EID: 0030459608     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961427e     Document Type: Article

References (34)

1. Adler, A. J., Greenfield, N. J., & Fasman, G. D. (1973) in Methods in Enzymology (Hirs, C. H. W., & Timasheff, S. N., Eds.) Vol. 27, pp 675-735, Academic Press, New York.
2. Betts, L., Xiang, S., Short, S., Wolfenden, R., & Carter, C. W., Jr. (1994) J. Mol. Biol. 235, 635-656.
3. Bhaumik, D., Medin, J., Gathy, K., & Coleman, M. S. (1993) J. Biol. Chem. 268, 5464-5470.
4. Bradford, M. (1976) Anal. Biochem 72, 248-254.
5. Carlow, D. A., Smith, A. A., Yang, C. C., Short, S. A., & Wolfenden, R. (1995) Biochemistry 34, 4220-4224.
6. Chang, Z., Nygaard, P., Chinault, A. C., & Kellems, R. E. (1991) Biochemistry 30, 2273-2280.
7. Freskard, P., Martensson, L., Jonasson, P., Jonsson, B., & Carlsson, U. (1994) Biochemistry 33, 14281-14288
8. Frick, L., Neela, J. P., & Wolfenden, R. (1987) Bioorg. Chem. 15, 100-108.
9. Jones, W., Kurz, L. C., & Wolfenden, R. Biochemistry 28, 1242-1247.
10. Kati, W. M., & Wolfenden, R. (1989) Science 243, 1591-1593.
11. Kline, P. C., & Schramm, V. L. (1994) J. Biol. Chem. 269, 22385-22390.
12. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
13. Kunkel, T. A., Roberts, J. D., & Zakour, R. A. (1987) Methods Enzymol. 154, 367-382.
14. Kurz, L. C., & Frieden, C. (1983) Biochemistry 22, 382-389.
15. Kurz, L. C., & Frieden, C. (1987) Biochemistry 26, 8450-8457.
16. Kurz, L. C., LaZard, D., & Frieden, C. (1985) Biochemistry 24, 1342-1347.
17. Kurz, L. C., Moix, L., Riley, M. C., & Frieden, C. (1992) Biochemistry 31, 39-48.
18. Laemmli, U. K. (1970) Nature 227, 680-685.
19. Liang, Z., Jonsson, B., & Lindskog, S. (1993) Biochim. Biophys. Acta 1203, 142-145.
20. Mohamedali, K. A., Kurz, L. C., & Rudolph, F. B. (1996) Biochemistry 35, 1672-1680.
21. Philips, A. V., Coleman, M. S., Maskos, K., & Barkley, M. D. (1989) Biochemistry 28, 2040-2050.
22. Porter, D. J. T., & Spector, T. (1993), J. Biol. Chem. 268, 2480-2485.
23. Sideraki, V., Mohamedali, K. A., Wilson, D. K., Chang, Z., Kellems, R. E., Quiocho, F. A., & Rudolph, F. B. (1996) Biochemistry 35, 7862-7872.
24. Vuilleumier, S., Sancho, J., Loewenthal, R. and Fersht, A. R. (1993) Biochemistry 32, 10303-10313.
25. Weiss, P. M., Cook, P. F., Hermes, J. D., & Cleland, W. W. (1987) Biochemistry 26, 7378-7384.
26. Wilson, D. K. (1996) Ph.D. Thesis, Baylor College of Medicine, Houston, TX.
27. Wilson, D. K., & Quiocho, F. A. (1993) Biochemistry 32, 1689-1693.
28. Wilson, D. K., & Quiocho, F. A. (1994) Struct. Biol. 1, 691-694.
29. Wilson, D. K., Rudolph, F. B., & Quiocho, F. A. (1991) Science 252, 1278-1284.
30. Wolfenden, R. (1969) Biochemistry 8, 2409-2412.
31. Wolfenden, R., Wentworth, D. F., & Mitchell, G. N. (1977) Biochemistry 16, 5071-5077.
32. Xu, X., Qin, X., & Kantrowitz, E. R. (1994) Biochemistry 33, 2279-2284.
33. Yeung, C., Ingolia, D. E., Roth, D. B., Shoemaker, C., Al-Ubaidi, M. R., Yen, J., Ching, C., Bobonis, C., Kaufman, R. J., & Kellems, R. E. (1985) J. Biol. Chem. 260, 10299-10307.
34. Zielke, C. L., & Suelter, C. H. (1971) in The Enzymes (Boyer, P. D., Ed.) Vol. 4, pp 47-48, Academic Press, New York.