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Volumn 26, Issue 5, 2004, Pages 554-557

Increased homocysteine and decreased adenosine formation in Alzheimer's disease

Author keywords

Adenosine; Alzheimer's disease; Homocysteine; Stroke; Vascular disease

Indexed keywords

ADENOSINE; HOMOCYSTEINE; S ADENOSYLHOMOCYSTEINE;

EID: 3042729591     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164104225016182     Document Type: Article
Times cited : (20)

References (56)
  • 1
    • 0031597388 scopus 로고    scopus 로고
    • 12 and serum total homocysteine levels in confirmed Alzheimer's disease
    • 12 and serum total homocysteine levels in confirmed Alzheimer's disease. Arch Neurol 1998; 55: 1449-1455
    • (1998) Arch Neurol , vol.55 , pp. 1449-1455
    • Clarke, R.1    Smith, A.D.2    Jobst, K.A.3
  • 2
    • 0031902352 scopus 로고    scopus 로고
    • Total serum homocysteine in senile dementia of Alzheimer type
    • McCaddon A, Davies G, Hudason P, et al. H. Total serum homocysteine in senile dementia of Alzheimer type. Int J Geriatr Psychiatry 1998; 13: 235-239
    • (1998) Int J Geriatr Psychiatry , vol.13 , pp. 235-239
    • McCaddon, A.1    Davies, G.2    Hudason, P.3
  • 3
    • 0033005334 scopus 로고    scopus 로고
    • Homocysteine and Alzheimer's disease
    • Miller JW. Homocysteine and Alzheimer's disease. Nutr Rev 1999; 57: 126-129
    • (1999) Nutr Rev , vol.57 , pp. 126-129
    • Miller, J.W.1
  • 4
    • 0037075257 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
    • Seshadri S, Beiser A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002; 346: 476-483
    • (2002) N Engl J Med , vol.346 , pp. 476-483
    • Seshadri, S.1    Beiser, A.2    Selhub, J.3
  • 5
    • 0028966321 scopus 로고
    • Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis
    • Selhub J, Jacques PF, Bostom AG, et al. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995; 332: 286-291
    • (1995) N Engl J Med , vol.332 , pp. 286-291
    • Selhub, J.1    Jacques, P.F.2    Bostom, A.G.3
  • 6
    • 0028788020 scopus 로고
    • Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study
    • Nygard O, Vollset SE, Refsum H, et al. Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. J Am Med Assoc 1995; 274: 1526-1533
    • (1995) J Am Med Assoc , vol.274 , pp. 1526-1533
    • Nygard, O.1    Vollset, S.E.2    Refsum, H.3
  • 7
    • 0030866856 scopus 로고    scopus 로고
    • High homocysteine levels are independently related to isolated systolic hypertension in older adults
    • Sutton-Tyrrell K, Bostom A, Selhub J, et al. High homocysteine levels are independently related to isolated systolic hypertension in older adults. Circulation 1997; 96: 1745-1749
    • (1997) Circulation , vol.96 , pp. 1745-1749
    • Sutton-Tyrrell, K.1    Bostom, A.2    Selhub, J.3
  • 8
    • 0035434682 scopus 로고    scopus 로고
    • Fasting plasma homocysteine levels in the insulin resistance syndrome: The Framingham offspring study
    • Meigs JB, Jacques PF, Selhub J, et al. Fasting plasma homocysteine levels in the insulin resistance syndrome: The Framingham offspring study. Diabetes Care 2001; 24: 1403-1410
    • (2001) Diabetes Care , vol.24 , pp. 1403-1410
    • Meigs, J.B.1    Jacques, P.F.2    Selhub, J.3
  • 9
    • 0034531374 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in poorly controlled type 2 diabetes patients
    • Drzewoski J, Czupryniak L, Chwatko G, et al. Hyperhomocysteinemia in poorly controlled type 2 diabetes patients. Diabetes Nutr Metab 2000; 13: 319-324
    • (2000) Diabetes Nutr Metab , vol.13 , pp. 319-324
    • Drzewoski, J.1    Czupryniak, L.2    Chwatko, G.3
  • 10
    • 0033533435 scopus 로고    scopus 로고
    • Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: The Framingham study
    • Bostom AG, Rosenberg IH, Silbershatz H, et al. Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: The Framingham study. Ann Intern Med 1999; 131: 352-355
    • (1999) Ann Intern Med , vol.131 , pp. 352-355
    • Bostom, A.G.1    Rosenberg, I.H.2    Silbershatz, H.3
  • 11
    • 0037385020 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is associated with the presence of left atrial thrombus in stroke patients with nonvalvular atrial fibrillation
    • Ay H, Arsava EM, Tokgozoglu SL, et al. Hyperhomocysteinemia is associated with the presence of left atrial thrombus in stroke patients with nonvalvular atrial fibrillation. Stroke 2003; 34: 909-912
    • (2003) Stroke , vol.34 , pp. 909-912
    • Ay, H.1    Arsava, E.M.2    Tokgozoglu, S.L.3
  • 12
    • 0031026879 scopus 로고    scopus 로고
    • Atherosclerosis, apolipoprotein E and prevalence of dementia and Alzheimer's disease in the Rotterdam Study
    • Hofman H, Ott A, Breteler MM, et al. Atherosclerosis, apolipoprotein E and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet 1997; 349: 151-154
    • (1997) Lancet , vol.349 , pp. 151-154
    • Hofman, H.1    Ott, A.2    Breteler, M.M.3
  • 13
    • 0035897938 scopus 로고    scopus 로고
    • Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study
    • Kivipelto M, Helkala E-L, Laakso MP, et al. Midlife vascular risk factors and Alzheimer's disease in later life: Longitudinal, population based study. Br Med J 2001; 322: 1447-1451
    • (2001) Br Med J , vol.322 , pp. 1447-1451
    • Kivipelto, M.1    Helkala, E.-L.2    Laakso, M.P.3
  • 14
    • 0027453765 scopus 로고
    • Untreated blood pressure level is inversely related to cognitive functioning: The Framington study
    • Elias ME, Wolf PA, D'Agostino RB, et al. Untreated blood pressure level is inversely related to cognitive functioning: The Framington study. Am J Epidemiol 1993; 138: 353-364
    • (1993) Am J Epidemiol , vol.138 , pp. 353-364
    • Elias, M.E.1    Wolf, P.A.2    D'Agostino, R.B.3
  • 15
    • 9844229370 scopus 로고    scopus 로고
    • Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: Cross sectional population based study
    • Kuusisto J, Koivisto K, Mykkänen L, et al. Association between features of the insulin resistance syndrome and Alzheimer's disease independently of apolipoprotein E4 phenotype: Cross sectional population based study. Br Med J 1997; 315: 1045-1049
    • (1997) Br Med J , vol.315 , pp. 1045-1049
    • Kuusisto, J.1    Koivisto, K.2    Mykkänen, L.3
  • 16
    • 0032764016 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia: The Rotterdam Study
    • Ott A, Stolk RP, van Harskamp F, et al. Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 1999; 53: 1937-1942
    • (1999) Neurology , vol.53 , pp. 1937-1942
    • Ott, A.1    Stolk, R.P.2    Van Harskamp, F.3
  • 17
    • 0347385146 scopus 로고    scopus 로고
    • Stroke and the risk of Alzheimer's disease
    • Honig LS, Tang MX, Albert S, et al. Stroke and the risk of Alzheimer's disease. Arch Neurol 2003; 60: 1707-1712
    • (2003) Arch Neurol , vol.60 , pp. 1707-1712
    • Honig, L.S.1    Tang, M.X.2    Albert, S.3
  • 18
    • 0031024446 scopus 로고    scopus 로고
    • Atrial fibrillation and dementia in a population-based study. The Rotterdam Study
    • Ott A, Breteler MM, de Bruyne MC, et al. Atrial fibrillation and dementia in a population-based study. The Rotterdam Study. Stroke 1997; 28: 316-321
    • (1997) Stroke , vol.28 , pp. 316-321
    • Ott, A.1    Breteler, M.M.2    De Bruyne, M.C.3
  • 19
    • 0037015259 scopus 로고    scopus 로고
    • Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal function
    • Chen Y-F, Li P-L, Zou A-P. Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal function. Circulation 2002; 106: 1275-1281
    • (2002) Circulation , vol.106 , pp. 1275-1281
    • Chen, Y.-F.1    Li, P.-L.2    Zou, A.-P.3
  • 20
    • 0142090595 scopus 로고    scopus 로고
    • Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia
    • Riksen NP, Rongen GA, Blom HJ, et al. Potential role for adenosine in the pathogenesis of the vascular complications of hyperhomocysteinemia. Cardiovasc Res 2003; 59: 271-276
    • (2003) Cardiovasc Res , vol.59 , pp. 271-276
    • Riksen, N.P.1    Rongen, G.A.2    Blom, H.J.3
  • 21
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA (National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association) Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhan G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA (National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association) Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984; 34: 939-944
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhan, G.1    Drachman, D.2    Folstein, M.3
  • 23
    • 0016823810 scopus 로고
    • "Mini-mental state." A practical method for grading the cognitive status of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive status of patients for the clinician. J Psychiatr Res 1975; 12: 189-198
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 24
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, et al. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984; 141: 1356-1364
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2
  • 25
    • 0032823860 scopus 로고    scopus 로고
    • Method for the determination of total homocysteine in plasma and urine by stable isotope dilution and electrospray tandem mass spectrometry
    • Magera MJ, Lacey JM, Casetta B, et al. Method for the determination of total homocysteine in plasma and urine by stable isotope dilution and electrospray tandem mass spectrometry. Clin Chem 1999; 45: 1517-1522
    • (1999) Clin Chem , vol.45 , pp. 1517-1522
    • Magera, M.J.1    Lacey, J.M.2    Casetta, B.3
  • 26
    • 0028075853 scopus 로고
    • Determination of plasma adenosine by high-performance liquid chromatography with column switching and fluorometric detection
    • Nithipatikom K, Mizumura T, Gross GJ. Determination of plasma adenosine by high-performance liquid chromatography with column switching and fluorometric detection. Anal Biochem 1994; 223: 280-284
    • (1994) Anal Biochem , vol.223 , pp. 280-284
    • Nithipatikom, K.1    Mizumura, T.2    Gross, G.J.3
  • 27
    • 0036447681 scopus 로고    scopus 로고
    • Vascular basis of Alzheimer's pathogenesis
    • de la Torre JC. Vascular basis of Alzheimer's pathogenesis. Ann NY Acad Sci 2002; 977: 196-215
    • (2002) Ann NY Acad Sci , vol.977 , pp. 196-215
    • De La Torre, J.C.1
  • 28
    • 0034603512 scopus 로고    scopus 로고
    • The role of cerebral ischemia in Alzheimer's disease
    • Kalaria RN. The role of cerebral ischemia in Alzheimer's disease. Neurobiol Aging 2000; 21: 321-330
    • (2000) Neurobiol Aging , vol.21 , pp. 321-330
    • Kalaria, R.N.1
  • 29
    • 0016224631 scopus 로고
    • Release of adenosine from ischemic brain. Effect on cerebral vascular resistance and incorporation into cerebral adenine nucleotides
    • Berne RM, Rubio R, Curnish RR. Release of adenosine from ischemic brain. Effect on cerebral vascular resistance and incorporation into cerebral adenine nucleotides. Circ Res 1974; 35: 262-271
    • (1974) Circ Res , vol.35 , pp. 262-271
    • Berne, R.M.1    Rubio, R.2    Curnish, R.R.3
  • 30
    • 0032101921 scopus 로고    scopus 로고
    • Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia
    • Coney AM, Marshall JM. Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia. J Physiol 1998; 509: 507-518
    • (1998) J Physiol , vol.509 , pp. 507-518
    • Coney, A.M.1    Marshall, J.M.2
  • 31
    • 0037106407 scopus 로고    scopus 로고
    • The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep
    • Blood A, Hunter CJ, Power GG. The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep. J Physiol 2002; 543: 1015-1023
    • (2002) J Physiol , vol.543 , pp. 1015-1023
    • Blood, A.1    Hunter, C.J.2    Power, G.G.3
  • 32
    • 0022979276 scopus 로고
    • Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia
    • Van Wylen DG, Park TS, Rubio R, et al. Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia. J Cereb Blood Flow Metab 1986; 6: 522-528
    • (1986) J Cereb Blood Flow Metab , vol.6 , pp. 522-528
    • Van Wylen, D.G.1    Park, T.S.2    Rubio, R.3
  • 33
    • 0023240964 scopus 로고
    • Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia
    • Hagberg H, Andersson P, Lacarewicz J, et al. Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J Neurochem 1987; 49: 227-231
    • (1987) J Neurochem , vol.49 , pp. 227-231
    • Hagberg, H.1    Andersson, P.2    Lacarewicz, J.3
  • 34
    • 0033065893 scopus 로고    scopus 로고
    • Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices
    • Latini S, Bordoni F, Pedata F, et al. Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices. Br J Pharmacol 1999; 127: 729-739
    • (1999) Br J Pharmacol , vol.127 , pp. 729-739
    • Latini, S.1    Bordoni, F.2    Pedata, F.3
  • 37
    • 0020554177 scopus 로고
    • Adenosine: A physiological modulator of superoxide anion generation by human neutrophils
    • Cronstein BN, Kramer SB, Weissmann G, et al. Adenosine: A physiological modulator of superoxide anion generation by human neutrophils. J Exp Med 1983; 158: 1160-1177
    • (1983) J Exp Med , vol.158 , pp. 1160-1177
    • Cronstein, B.N.1    Kramer, S.B.2    Weissmann, G.3
  • 41
    • 0027154950 scopus 로고
    • Inhibition of human monocytic TNF production by adenosine receptor agonists
    • Le Vraux V, Chen YL, Masson I, et al. Inhibition of human monocytic TNF production by adenosine receptor agonists. Life Sci 1993; 52: 1917-1924
    • (1993) Life Sci , vol.52 , pp. 1917-1924
    • Le Vraux, V.1    Chen, Y.L.2    Masson, I.3
  • 42
    • 0029360536 scopus 로고
    • 2 receptors, adenosine inhibits the production of tumor necrosis factor-α of endotoxin-stimulated human polymorphonuclear leukocytes
    • 2 receptors, adenosine inhibits the production of tumor necrosis factor-α of endotoxin-stimulated human polymorphonuclear leukocytes. J Lab Clin Med 1995; 126: 275-282
    • (1995) J Lab Clin Med , vol.126 , pp. 275-282
    • Thiel, M.1    Chouker, A.2
  • 43
    • 0033820684 scopus 로고    scopus 로고
    • 2A receptor-dependent and independent mechanisms
    • 2A receptor-dependent and independent mechanisms. FASEB J 2000; 14: 2065-2074
    • (2000) FASEB J , vol.14 , pp. 2065-2074
    • Hasko, G.1    Kuhel, D.G.2    Chen, J.F.3
  • 44
    • 0029968687 scopus 로고    scopus 로고
    • Adenosine inhibits cytokine release and expression of adhesion molecules by activated human endothelial cells
    • Bouma MG, van den Wildenberg FA, Buurman WA. Adenosine inhibits cytokine release and expression of adhesion molecules by activated human endothelial cells. Am J Physiol 1996; 270: C522-C529
    • (1996) Am J Physiol , vol.270
    • Bouma, M.G.1    Van Den Wildenberg, F.A.2    Buurman, W.A.3
  • 45
    • 0348222661 scopus 로고    scopus 로고
    • Adenosine: An endogenous regulator of innate immunity
    • Hasko G, Cronstein BN. Adenosine: An endogenous regulator of innate immunity. Trends Immunol 2004; 25: 33-39
    • (2004) Trends Immunol , vol.25 , pp. 33-39
    • Hasko, G.1    Cronstein, B.N.2
  • 46
    • 0035146235 scopus 로고    scopus 로고
    • Dysregulation of extracellular adenosine levels by vascular smooth muscle cells from spontaneously hypertensive rats
    • Dubey R, Mi Z, Gillespie DG, et al. Dysregulation of extracellular adenosine levels by vascular smooth muscle cells from spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol 2001; 21: 249-254
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 249-254
    • Dubey, R.1    Mi, Z.2    Gillespie, D.G.3
  • 47
    • 0033958349 scopus 로고    scopus 로고
    • 2B receptors mediate antimitogenesis in vascular smooth muscle cells
    • 2B receptors mediate antimitogenesis in vascular smooth muscle cells. Hypertension 2000; 35: 267-272
    • (2000) Hypertension , vol.35 , pp. 267-272
    • Dubey, R.K.1    Gillespie, D.G.2    Shue, H.3
  • 48
    • 0032901401 scopus 로고    scopus 로고
    • Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells
    • Dubey RK, Gillespie DG, Jackson EK. Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells. Hypertension 1999; 33: 267-272
    • (1999) Hypertension , vol.33 , pp. 267-272
    • Dubey, R.K.1    Gillespie, D.G.2    Jackson, E.K.3
  • 49
    • 0031054674 scopus 로고    scopus 로고
    • Brain infarction and the clinical expression of Alzheimer's disease. The Nun Study
    • Snowdon DA, Greiner LH, Mortimer JA, et al. Brain infarction and the clinical expression of Alzheimer's disease. The Nun Study. J Am Med Assoc 1997; 277: 813-817
    • (1997) J Am Med Assoc , vol.277 , pp. 813-817
    • Snowdon, D.A.1    Greiner, L.H.2    Mortimer, J.A.3
  • 50
    • 0023103372 scopus 로고
    • Evidence for an anti-aggregatory effect of adenosine at physiological concentrations and for its role in the action of dipyridamole
    • Edlund A, Siden A, Sollevi A. Evidence for an anti-aggregatory effect of adenosine at physiological concentrations and for its role in the action of dipyridamole. Thromb Res 1987; 45: 183-190
    • (1987) Thromb Res , vol.45 , pp. 183-190
    • Edlund, A.1    Siden, A.2    Sollevi, A.3
  • 52
    • 0032528307 scopus 로고    scopus 로고
    • Adenosine regulates tissue factor expression on endothelial cells
    • Deguchi H, Takeya H, Urano H, et al. Adenosine regulates tissue factor expression on endothelial cells. Thromb Res 1998; 91: 57-64
    • (1998) Thromb Res , vol.91 , pp. 57-64
    • Deguchi, H.1    Takeya, H.2    Urano, H.3
  • 53
    • 0032522983 scopus 로고    scopus 로고
    • Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs
    • Minamino T, Kitakaze M, Asanuma H, et al. Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs. J Clin Invest 1998; 101: 1643-1653
    • (1998) J Clin Invest , vol.101 , pp. 1643-1653
    • Minamino, T.1    Kitakaze, M.2    Asanuma, H.3
  • 54
    • 0033555540 scopus 로고    scopus 로고
    • Plasma adenosine levels and platelet activation in patients with atrial fibrillation
    • Minamino T, Kitakaze M, Asanuma H, et al. Plasma adenosine levels and platelet activation in patients with atrial fibrillation. Am J Cardiol 1999; 83: 194-198
    • (1999) Am J Cardiol , vol.83 , pp. 194-198
    • Minamino, T.1    Kitakaze, M.2    Asanuma, H.3
  • 55
    • 0025786178 scopus 로고
    • Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives
    • Ohkubo T, Mitsumoto Y, Mohri T. Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives. Neurosci Lett 1991; 133: 275-278
    • (1991) Neurosci Lett , vol.133 , pp. 275-278
    • Ohkubo, T.1    Mitsumoto, Y.2    Mohri, T.3
  • 56
    • 0030668582 scopus 로고    scopus 로고
    • Clinical trials in dementia with propentofylline
    • Kittner B, Rossner M, Rother M. Clinical trials in dementia with propentofylline. Ann NY Acad Sci 1997; 826: 307-316
    • (1997) Ann NY Acad Sci , vol.826 , pp. 307-316
    • Kittner, B.1    Rossner, M.2    Rother, M.3


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