Allosteric modulation of A(2A) adenosine receptors by amiloride analogues and sodium ions

Biochemical Pharmacology

Volumn 60, Issue 5, 2000, Pages 669-676

  Gao, Zhan Guo ^a   Ijzerman, Adriaan P ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

3H ZM241385; A(2A) adenosine receptor; Allosteric modulation; Amiloride; Sodium ion

Indexed keywords

4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 5 (N GUANIDONOCARBONYLMETHYL N ETHYL)AMILORIDE; 5 (N,N HEXAMETHYLENE)AMILORIDE; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE A2A RECEPTOR; AMILORIDE; BENZAMIL; GUANOSINE TRIPHOSPHATE; N ETHYLMALEIMIDE; PHENAMIL; SODIUM ION; SURAMIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; RECEPTOR BINDING;

ALLOSTERIC REGULATION; AMILORIDE; ANIMALS; BINDING, COMPETITIVE; CELL MEMBRANE; CORPUS STRIATUM; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; RADIOPHARMACEUTICALS; RATS; RECEPTOR, ADENOSINE A2A; RECEPTORS, PURINERGIC P1; SODIUM; SODIUM CHLORIDE; TIME FACTORS; TRIAZINES; TRIAZOLES; TRITIUM;

EID: 0034284626     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00360-9     Document Type: Article

References (35)

1. Palmer T.M., Stiles G.L. Adenosine receptors. Neuropharmacology. 34:1995;683-694.
2. Martin G.E., Rossi D.J., Jarvis M.F. Adenosine agonists reduce conditioned avoidance responding in the rat. Pharmacol Biochem Behav. 45:1993;951-958.
3. Nikodijevic O., Jacobson K.A., Daly J.W. Acute treatment of mice with high-doses of caffeine An animal model for choreiform movement . Drug Dev Res. 30:1993;121-128.
4. 2A receptor antagonist with anticataleptic activity . Eur J Pharmacol. 256:1994;263-268.
5. Tucek S., Proska J. Allosteric modulation of muscarinic acetylcholine receptors. Trends Pharmacol Sci. 16:1995;205-212.
6. Gao Z.G., Liu C.G. Competitive and allosteric binding of 2α-DHET and its optical isomers to rat cardiac muscarinic receptors. Eur J Pharmacol. 289:1995;369-373.
7. Birdsall N.J., Farries T., Gharagozloo P., Kobayashi S., Lazareno S., Sugimoto M. Subtype-selective positive cooperative interactions between brucine analogs and acetylcholine at muscarinic receptors Functional studies . Mol Pharmacol. 55:1999;778-786.
8. Gharagozloo P., Lazareno S., Popham A., Birdsall N.J. Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors. J Med Chem. 42:1999;438-445.
9. 4 muscarinic receptors. Life Sci. 64:1999;519-526.
10. Birdsall N.J., Hulme E.C., Kromer W., Peck B.S., Stockton J.M., Zigmond M.J. Two drug binding sites on muscarinic receptors. Briley M., Kato A., Weber M. New Concepts in Alzheimer's Disease. 1986;103-121 Macmillan, London.
11. Barker J.L., Harrison N.L., Mariani A.P. Benzodiazepine pharmacology of cultured mammalian CNS neurons. Life Sci. 39:1986;1959-1968.
12. 1 receptor binding and function by 2-amino-3-benzoylthiophenes. Mol Pharmacol. 38:1990;939-949.
13. 1 receptor binding by 2-amino-3-benzoylthiophenes. Mol Pharmacol. 38:1990;950-958.
14. +, and amiloride analogues. J Biol Chem. 265:1990;17307-17317.
15. 2 receptor affinity for drugs and inhibition of adenylyl cyclase. Mol Pharmacol. 39:1991;733-739.
16. 2B-adrenergic receptor subtype. Mol Pharmacol. 39:1991;481-486.
17. 2A-adrenergic receptor. Mol Pharmacol. 53:1998;916-925.
18. + exchange. J Biol Chem. 262:1987;12387-12392.
19. Kleyman T.R., Cragoe E.J. Jr. Cation transport probes The amiloride series . Methods Enzymol. 191:1990;739-755.
20. 1 adenosine receptors Influences of acidic and hydroxy residues in the first four transmembrane domains on ligand binding . Mol Pharmacol. 50:1996;1635-1642.
21. 1 receptor. Neurochem Int. 20:1992;207-213.
22. 2A receptor. Critical involvement of Glu13 in agonist recognition. Eur J Pharmacol. 310:1996;269-272.
23. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N.M., Olson B.J., Klenk D.C. Measurement of protein using bicinchoninic acid. Anal Biochem. 150:1985;76-85.
24. 50) of an enzymatic reaction. Biochem Pharmacol. 22:1973;3099-3108.
25. Arunlakshama O., Schild H.O. Some quantitative uses of drug antagonists. Br J Pharmacol Chemother. 14:1959;48-58.
26. 2-adrenergic receptors by sodium. J Biol Chem. 265:1990;21590-21595.
27. 2A-adrenergic receptor that eliminate detectable palmitoylation do not perturb receptor-G-protein coupling. J Biol Chem. 268:1993;8003-8011.
28. + exchanger in renal microvillus membrane vesicles. Am J Physiol. 241:1981;F374-F379.
29. + exchanger. J Biol Chem. 260:1985;12586-12592.
30. + exchange system. Mol Pharmacol. 25:1984;131-136.
31. 2 dopamine receptors by amiloride and amiloride analogs. Mol Pharmacol. 50:1996;1295-1308.
32. 2-adrenergic receptors . Mol Pharmacol. 32:1987;53-58.
33. 1 receptors in calf brain. Biochem Pharmacol. 40:1990;827-834.
34. 1 receptors. Implications for the interaction with R-PIA, DPCPX and amiloride. Biochem Pharmacol. 40:1990;835-842.
35. Henis Y.I., Kloog Y., Sokolovsky M. Allosteric interactions of muscarinic receptors and their regulation by other membrane proteins. Brown J.H. The Muscarinic Receptors. 1989;377-418 Humana Press, Totowa NJ.