Allosteric modulators of human A2B adenosine receptor

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 3, 2014, Pages 1194-1203

  Trincavelli, Maria Letizia ^a   Giacomelli, Chiara ^a   Daniele, Simona ^a   Taliani, Sabrina ^a   Cosimelli, Barbara ^b   Laneri, Sonia ^b   Severi, Elda ^b   Barresi, Elisabetta ^a   Pugliesi, Isabella ^a   Greco, Giovanni ^b   Novellino, Ettore ^b   Da Settimo, Federico ^a   Martini, Claudia ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

1 Benzyl 3 ketoindole derivatives; A2B adenosine receptor; GPCR allosteric modulators; Ligand receptor interaction; Negative allosteric modulators; Positive allosteric modulators

Indexed keywords

1 BENZYL 3 KETOINDOLE DERIVATIVE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; BAY 606583; CYCLIC AMP; UNCLASSIFIED DRUG;

ADRENERGIC STIMULATION; ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG TARGETING; FEMALE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

2-[6-AMINO-3,5-DICYANO-4-[4-(CYCLOPROPYLMETHOXY)PHENYL]PYRIDIN-2-YLSULFANYL]ACETAMIDE; [(3)H]N-(4-CYANOPHENYL)-2-[4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1,3-DIPROPYL-1H-PURIN-8-YL)-PHENOXY]ACETAMIDE; 1-BENZYL-3-KETOINDOLE DERIVATIVES; 3′,5′-CYCLIC ADENOSINE MONOPHOSPHATE; 4-(3-BUTOXY-4-METHOXYPHENYL)METHYL-2-IMIDAZOLIDONE; 4-DIMETHYLAMINOPYRIDINE; A(2B) ADENOSINE RECEPTOR; ADA; ADENOSINE DEAMINASE; ADENOSINE RECEPTOR; AR; BAY 60-6583; CAMP; CHINESE HAMSTER OVARY; CHO; DMAP; DMEM; DULBECCO'S MODIFIED EAGLE MEDIUM; G PROTEIN-COUPLED RECEPTOR; GPCR; GPCR ALLOSTERIC MODULATORS; LIGAND-RECEPTOR INTERACTION; NEGATIVE ALLOSTERIC MODULATORS; POSITIVE ALLOSTERIC MODULATORS; RO 20-1724; [(3)H]5′-N-ETHYLCARBOXAMIDEADENOSINE; [(3)H]MRS 1754; [(3)H]NECA; [(35)S]GTPΓS; [(35)S]GUANOSINE 5′-O-[GAMMA-THIO]TRIPHOSPHATE;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ALLOSTERIC REGULATION; CYCLIC AMP; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; RECEPTOR, ADENOSINE A2B;

EID: 84891705975     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.12.021     Document Type: Article

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