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Volumn 7, Issue 7, 2012, Pages

The A2b adenosine receptor modulates glucose homeostasis and obesity

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2B RECEPTOR; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; PROTEIN KINASE B; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL;

EID: 84864349274     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040584     Document Type: Article
Times cited : (105)

References (55)
  • 1
    • 0036092239 scopus 로고    scopus 로고
    • Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
    • McGarry JD, (2002) Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 51: 7-18.
    • (2002) Diabetes , vol.51 , pp. 7-18
    • McGarry, J.D.1
  • 2
    • 0027406191 scopus 로고
    • Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial
    • Stamler J, Vaccaro O, Neaton JD, Wentworth D, (1993) Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes care 16: 434-444.
    • (1993) Diabetes Care , vol.16 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 3
    • 65449128798 scopus 로고    scopus 로고
    • Central obesity and multivariable cardiovascular risk as assessed by the Framingham prediction scores
    • Dhaliwal SS, Welborn TA, (2009) Central obesity and multivariable cardiovascular risk as assessed by the Framingham prediction scores. The American journal of cardiology 103: 1403-1407.
    • (2009) The American Journal of Cardiology , vol.103 , pp. 1403-1407
    • Dhaliwal, S.S.1    Welborn, T.A.2
  • 5
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky JM, Glass CK, (2010) Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 72: 219-246.
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 6
    • 66949135415 scopus 로고    scopus 로고
    • Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
    • Yang J, Park Y, Zhang H, Xu X, Laine GA, et al. (2009) Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice. Am J Physiol Heart Circ Physiol 296: H1850-1858.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Yang, J.1    Park, Y.2    Zhang, H.3    Xu, X.4    Laine, G.A.5
  • 7
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, et al. (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 11: 183-190.
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5
  • 8
    • 58149164756 scopus 로고    scopus 로고
    • Mechanisms of induction of adenosine receptor genes and its functional significance
    • St Hilaire C, Carroll SH, Chen H, Ravid K, (2009) Mechanisms of induction of adenosine receptor genes and its functional significance. Journal of cellular physiology 218: 35-44.
    • (2009) Journal of Cellular Physiology , vol.218 , pp. 35-44
    • St Hilaire, C.1    Carroll, S.H.2    Chen, H.3    Ravid, K.4
  • 9
    • 85047678432 scopus 로고
    • Cloned receptors and cardiovascular responses to adenosine
    • Tucker AL, Linden J, (1993) Cloned receptors and cardiovascular responses to adenosine. Cardiovascular research 27: 62-67.
    • (1993) Cardiovascular Research , vol.27 , pp. 62-67
    • Tucker, A.L.1    Linden, J.2
  • 10
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • AP IJ
    • Fredholm BB, AP IJ, Jacobson KA, Klotz KN, Linden J, (2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacological reviews 53: 527-552.
    • (2001) Pharmacological Reviews , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Jacobson, K.A.2    Klotz, K.N.3    Linden, J.4
  • 12
    • 0031695494 scopus 로고    scopus 로고
    • Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions
    • Han DH, Hansen PA, Nolte LA, Holloszy JO, (1998) Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions. Diabetes 47: 1671-1675.
    • (1998) Diabetes , vol.47 , pp. 1671-1675
    • Han, D.H.1    Hansen, P.A.2    Nolte, L.A.3    Holloszy, J.O.4
  • 13
    • 0024271688 scopus 로고
    • Adenosine is required for myocardial insulin responsiveness in vivo
    • Law WR, McLane MP, Raymond RM, (1988) Adenosine is required for myocardial insulin responsiveness in vivo. Diabetes 37: 842-845.
    • (1988) Diabetes , vol.37 , pp. 842-845
    • Law, W.R.1    McLane, M.P.2    Raymond, R.M.3
  • 14
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, et al. (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nature medicine 11: 183-190.
    • (2005) Nature Medicine , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5
  • 15
    • 79551591770 scopus 로고    scopus 로고
    • Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans
    • Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, et al. (2011) Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans. Diabetes 60: 669-679.
    • (2011) Diabetes , vol.60 , pp. 669-679
    • Figler, R.A.1    Wang, G.2    Srinivasan, S.3    Jung, D.Y.4    Zhang, Z.5
  • 16
    • 0346880505 scopus 로고    scopus 로고
    • Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance
    • Shoelson SE, Lee J, Yuan M, (2003) Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance. Int J Obes Relat Metab Disord 27: S49-52.
    • (2003) Int J Obes Relat Metab Disord , vol.27
    • Shoelson, S.E.1    Lee, J.2    Yuan, M.3
  • 17
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, et al. (1995) Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature medicine 1: 1155-1161.
    • (1995) Nature Medicine , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3    Pratley, R.E.4    Lee, G.H.5
  • 18
    • 69449107989 scopus 로고    scopus 로고
    • IKKepsilon: a bridge between obesity and inflammation
    • Olefsky JM, (2009) IKKepsilon: a bridge between obesity and inflammation. Cell 138: 834-836.
    • (2009) Cell , vol.138 , pp. 834-836
    • Olefsky, J.M.1
  • 20
    • 37549022688 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • de Luca C, Olefsky JM, (2008) Inflammation and insulin resistance. FEBS letters 582: 97-105.
    • (2008) FEBS Letters , vol.582 , pp. 97-105
    • de Luca, C.1    Olefsky, J.M.2
  • 22
    • 70350463546 scopus 로고    scopus 로고
    • Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion
    • Bouzakri K, Ribaux P, Halban PA, (2009) Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion. The Journal of biological chemistry 284: 27892-27898.
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 27892-27898
    • Bouzakri, K.1    Ribaux, P.2    Halban, P.A.3
  • 24
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
    • Shimomura I, Matsuda M, Hammer RE, Bashmakov Y, Brown MS, et al. (2000) Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Molecular cell 6: 77-86.
    • (2000) Molecular Cell , vol.6 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3    Bashmakov, Y.4    Brown, M.S.5
  • 25
    • 0033966768 scopus 로고    scopus 로고
    • Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2
    • Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, et al. (2000) Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2. The Journal of clinical investigation 105: 199-205.
    • (2000) The Journal of Clinical Investigation , vol.105 , pp. 199-205
    • Kido, Y.1    Burks, D.J.2    Withers, D.3    Bruning, J.C.4    Kahn, C.R.5
  • 27
    • 65649129311 scopus 로고    scopus 로고
    • Adenosine signaling contributes to ethanol-induced fatty liver in mice
    • Peng Z, Borea PA, Varani K, Wilder T, Yee H, et al. (2009) Adenosine signaling contributes to ethanol-induced fatty liver in mice. J Clin Invest 119: 582-594.
    • (2009) J Clin Invest , vol.119 , pp. 582-594
    • Peng, Z.1    Borea, P.A.2    Varani, K.3    Wilder, T.4    Yee, H.5
  • 28
    • 0029046673 scopus 로고
    • Effects of a 48-h fat infusion on insulin secretion and glucose utilization
    • Boden G, Chen X, Rosner J, Barton M, (1995) Effects of a 48-h fat infusion on insulin secretion and glucose utilization. Diabetes 44: 1239-1242.
    • (1995) Diabetes , vol.44 , pp. 1239-1242
    • Boden, G.1    Chen, X.2    Rosner, J.3    Barton, M.4
  • 29
    • 0032030866 scopus 로고    scopus 로고
    • Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation
    • Bollheimer LC, Skelly RH, Chester MW, McGarry JD, Rhodes CJ, (1998) Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. The Journal of clinical investigation 101: 1094-1101.
    • (1998) The Journal of Clinical Investigation , vol.101 , pp. 1094-1101
    • Bollheimer, L.C.1    Skelly, R.H.2    Chester, M.W.3    McGarry, J.D.4    Rhodes, C.J.5
  • 31
    • 0024564466 scopus 로고
    • Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women
    • Despres JP, Nadeau A, Tremblay A, Ferland M, Moorjani S, et al. (1989) Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women. Diabetes 38: 304-309.
    • (1989) Diabetes , vol.38 , pp. 304-309
    • Despres, J.P.1    Nadeau, A.2    Tremblay, A.3    Ferland, M.4    Moorjani, S.5
  • 32
    • 0022413863 scopus 로고
    • Effects of dietary fat on postprandial substrate oxidation and on carbohydrate and fat balances
    • Flatt JP, Ravussin E, Acheson KJ, Jequier E, (1985) Effects of dietary fat on postprandial substrate oxidation and on carbohydrate and fat balances. The Journal of clinical investigation 76: 1019-1024.
    • (1985) The Journal of Clinical Investigation , vol.76 , pp. 1019-1024
    • Flatt, J.P.1    Ravussin, E.2    Acheson, K.J.3    Jequier, E.4
  • 33
    • 46349090125 scopus 로고    scopus 로고
    • The reno-vascular A2B adenosine receptor protects the kidney from ischemia
    • Grenz A, Osswald H, Eckle T, Yang D, Zhang H, et al. (2008) The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS medicine 5: e137.
    • (2008) PLoS Medicine , vol.5
    • Grenz, A.1    Osswald, H.2    Eckle, T.3    Yang, D.4    Zhang, H.5
  • 34
    • 34250376089 scopus 로고    scopus 로고
    • Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular disease
    • Franco OH, Steyerberg EW, Hu FB, Mackenbach J, Nusselder W, (2007) Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular disease. Archives of internal medicine 167: 1145-1151.
    • (2007) Archives of Internal Medicine , vol.167 , pp. 1145-1151
    • Franco, O.H.1    Steyerberg, E.W.2    Hu, F.B.3    Mackenbach, J.4    Nusselder, W.5
  • 39
    • 3042745158 scopus 로고    scopus 로고
    • Characterization of adenosine-A1 receptor-mediated antilipolysis in rats by tissue microdialysis, 1H-spectroscopy, and glucose clamp studies
    • Schoelch C, Kuhlmann J, Gossel M, Mueller G, Neumann-Haefelin C, et al. (2004) Characterization of adenosine-A1 receptor-mediated antilipolysis in rats by tissue microdialysis, 1H-spectroscopy, and glucose clamp studies. Diabetes 53: 1920-1926.
    • (2004) Diabetes , vol.53 , pp. 1920-1926
    • Schoelch, C.1    Kuhlmann, J.2    Gossel, M.3    Mueller, G.4    Neumann-Haefelin, C.5
  • 40
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS, (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. The Journal of clinical investigation 109: 1125-1131.
    • (2002) The Journal of Clinical Investigation , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 41
    • 79954633239 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein
    • Persaud SJ, Liu B, Sampaio HB, Jones PM, Muller DS, (2011) Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein. Diabetologia 54: 1109-1120.
    • (2011) Diabetologia , vol.54 , pp. 1109-1120
    • Persaud, S.J.1    Liu, B.2    Sampaio, H.B.3    Jones, P.M.4    Muller, D.S.5
  • 42
    • 0015882267 scopus 로고
    • Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect
    • Crespin SR, Greenough WB 3rd, Steinberg D (1973) Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect. The Journal of clinical investigation 52: 1979-1984.
    • (1973) The Journal of Clinical Investigation , vol.52 , pp. 1979-1984
    • Crespin, S.R.1    Greenough 3rd, W.B.2    Steinberg, D.3
  • 44
    • 64249144492 scopus 로고    scopus 로고
    • Activation of the macrophage A2b adenosine receptor regulates tumor necrosis factor-alpha levels following vascular injury
    • Chen H, Yang D, Carroll SH, Eltzschig HK, Ravid K, (2009) Activation of the macrophage A2b adenosine receptor regulates tumor necrosis factor-alpha levels following vascular injury. Experimental hematology 37: 533-538.
    • (2009) Experimental Hematology , vol.37 , pp. 533-538
    • Chen, H.1    Yang, D.2    Carroll, S.H.3    Eltzschig, H.K.4    Ravid, K.5
  • 45
    • 0028587742 scopus 로고
    • Tumor necrosis factor alpha: a key component of the obesity-diabetes link
    • Hotamisligil GS, Spiegelman BM, (1994) Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 43: 1271-1278.
    • (1994) Diabetes , vol.43 , pp. 1271-1278
    • Hotamisligil, G.S.1    Spiegelman, B.M.2
  • 47
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, et al. (1996) IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271: 665-668.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5
  • 49
    • 54249149973 scopus 로고    scopus 로고
    • Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span
    • Dixit VD, (2008) Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span. J Leukoc Biol 84: 882-892.
    • (2008) J Leukoc Biol , vol.84 , pp. 882-892
    • Dixit, V.D.1
  • 50
    • 56749164791 scopus 로고    scopus 로고
    • Nutrient sensing and inflammation in metabolic diseases
    • Hotamisligil GS, Erbay E, (2008) Nutrient sensing and inflammation in metabolic diseases. Nat Rev Immunol 8: 923-934.
    • (2008) Nat Rev Immunol , vol.8 , pp. 923-934
    • Hotamisligil, G.S.1    Erbay, E.2
  • 51
    • 79751512463 scopus 로고    scopus 로고
    • The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
    • Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, et al. (2011) The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 17: 179-188.
    • (2011) Nat Med , vol.17 , pp. 179-188
    • Vandanmagsar, B.1    Youm, Y.H.2    Ravussin, A.3    Galgani, J.E.4    Stadler, K.5
  • 54
    • 34247343418 scopus 로고    scopus 로고
    • Cardioprotection by ecto-5′-nucleotidase (CD73) and A2B adenosine receptors
    • Eckle T, Krahn T, Grenz A, Kohler D, Mittelbronn M, et al. (2007) Cardioprotection by ecto-5′-nucleotidase (CD73) and A2B adenosine receptors. Circulation 115: 1581-1590.
    • (2007) Circulation , vol.115 , pp. 1581-1590
    • Eckle, T.1    Krahn, T.2    Grenz, A.3    Kohler, D.4    Mittelbronn, M.5


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