Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity

Biochemical Journal

Volumn 391, Issue 1, 2005, Pages 51-57

  Zavialov, Andrey V ^a   Engström, Åke ^b  

^a Institute of Immunology   (Russian Federation)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Adenosine deaminase (ADA); Cat eye syndrome critical region candidate 1 (CECR1); Growth factor; Heparin; Immunoglobulin G (IgG); Macrophage

Indexed keywords

ACIDITY; BIOCHEMISTRY; CELLS; PH EFFECTS; PHYSIOLOGY; PROTEINS;

ADENOSINE DEAMINASE (ADA); HEPARIN-BINDING PROTEINS; MONOCYTES;

ENZYMES;

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE 2; GROWTH FACTOR; HEPARIN BINDING PROTEIN; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; INFLAMMATION; LYMPHOCYTE ACTIVATION; MONOCYTE; PH; PRIORITY JOURNAL; TUMOR GROWTH;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE DEAMINASE; AMINO ACID SEQUENCE; CATALYSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; COLD; COMPUTATIONAL BIOLOGY; ETHANOL; GROWTH SUBSTANCES; HUMANS; IMMUNOGLOBULIN G; ISOENZYMES; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

EID: 26844457398     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050683     Document Type: Article

References (42)

1. Ratech, H., Thorbecke, G. J., Meredith, G. and Hirschhorn, R. (1981) Comparison and possible homology of isozymes of adenosine deaminase in Aves and humans. Enzyme 26, 74-84
2. Schrader, W. P., Woodward, F. J. and Pollara, B. (1979) Purification of an adenosine deaminase complexing protein from human plasma. J. Biol. Chem. 254, 11964-11968
3. Weihofen, W. A., Liu, J., Reutter, W., Saenger, W. and Fan, H. (2004) Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J. Biol. Chem. 279, 43330-43335
4. Ungerer, J. P., Oosthuizen, H. M., Bissbort, S. H. and Vermaak, W. J. (1992) Serum adenosine deaminase: isoenzymes and diagnostic application. Clin. Chem. 38, 1322-1326
5. Thompson, L. F. and Seegmiller, J. E. (1980) Adenosine deaminase deficiency and severe combined immunodeficiency disease. Adv. Enzymol. Relat. Areas Mol. Biol. 51, 167-210
6. Wilson, D. K., Rudolph, F. B. and Quiocho, F. A. (1991) Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations. Science 252, 1278-1284
7. Daddona, P. E. and Kelley, W. N. (1977) Human adenosine deaminase. Purification and subunit structure. J. Biol. Chem. 252, 110-115
8. Ciruela, F., Saura, C., Canela, E. I., Mallol, J., Lluis, C. and Franco, R. (1996) Adenosine deaminase affects ligand-induced signalling by interacting with cell surface adenosine receptors. FEBS Lett. 380, 219-223
9. Herrera, C., Casado, V., Ciruela, F., Schofield, P., Mallol, J., Lluis, C. and Franco, R. (2001) Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells. Mol. Pharmacol. 59, 127-134
10. Weihofen, W. A., Liu, J., Reutter, W., Saenger, W. and Fan, H. (2005) Crystal structures of HIV-1 Tat derived nonapeptides Tat(1-9) and Trp2-Tat(1-9) bound to the active site of dipeptidyl peptidase IV (CD26). J. Biol. Chem. 280, 14911-14917
11. Rokosu, A. A. (1983) The characterization of an adenosine deaminase from chicken serum. Comp. Biochem. Physiol. B 74, 441-444
12. Daddona, P. E. and Kelley, W. N. (1981) Characteristics of an aminohydrolase distinct from adenosine deaminase in cultured human lymphoblasts. Biochim. Biophys. Acta 658, 280-290
13. Conlon, B. A. and Law, W. R. (2004) Macrophages are a source of extracellular adenosine deaminase-2 during inflammatory responses. Clin. Exp. Immunol. 138, 14-20
14. Tsuboi, I., Sagawa, K., Shichijo, S., Yokoyama, M. M., Ou, D. W. and Wiederhold, M. D. (1995) Adenosine deaminase isoenzyme levels in patients with human T-cell lymphotropic virus type 1 and human immunodeficiency virus type 1 infections. Clin. Diagn. Lab. Immunol. 2, 626-630
15. Perez-Rodriguez, E. and Jimenez Castro, D. (2000) The use of adenosine deaminase and adenosine deaminase isoenzymes in the diagnosis of tuberculous pleuritis. Curr. Opin. Pulm. Med. 6, 259-266
16. Niedzwicki, J. G., Mayer, K. H., Abushanab, E. and Abernethy, D. R. (1991) Plasma adenosine deaminase2 is a marker for human immunodeficiency virus-1 seroconversion. Am. J. Hematol. 37, 152-155
17. Hitoglou, S., Hatzistilianou, M., Gougoustamou, D., Athanassiadou, F., Kotsis, A. and Catriu, D. (2001) Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus. Clin. Rheumatol. 20, 411-416
18. German, D. C. and Kredich, N. M. (1984) A radioenzymatic assay for plasma adenosine. Anal. Biochem. 142, 536-541
19. Niedzwicki, J. G. and Abernethy, D. R. (1991) Structure-activity relationship of ligands of human plasma adenosine deaminase2. Biochem. Pharmacol. 41, 1615-1624
20. Iwaki-Egawa, S., Namiki, C. and Watanabe, Y. (2004) Adenosine deaminase 2 from chicken liver: purification, characterization, and N-terminal amino acid sequence. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 137, 247-254
21. Andreasyan, N. A., Hairapetyan, H. L., Sargisova, Y. G. and Mardanyan, S. S. (2005) ADA2 isoform of adenosine deaminase from pleural fluid. FEBS Lett. 579, 643-647
22. Cohn, E. J., Strong, L. E., Hughes, W. L., Mulford, D. J., Ashworth, J. N., Melin, M. and Taylor, H. L. (1946) Preparation and properties of serum and plasma proteins. IV. A system for the separation into fractions of the protein and lipoprotein components of biological tissues and fluids. J. Am. Chem. Soc. 68, 459-475
23. Zavialov, A. V., Buckingham, R. H. and Ehrenberg, M. (2001) A posttermination ribosomal complex is the guanine nucleotide exchange factor for peptide release factor RF3. Cell (Cambridge, Mass.) 107, 115-124
24. Aoyagi, S., Hirayanagi, K., Yoshimura, T. and Ishikawa, T. (1982) Preparative separation of nucleosides and nucleotides on a non-ionic gel column. J. Chromatogr. A 253, 133-137
25. Zavialov, A. V. and Ehrenberg, M. (2003) Peptidyl-tRNA regulates the GTPase activity of translation factors. Cell (Cambridge, Mass.) 114, 113-122
26. Riazi, M. A., Brinkman-Mills, P., Nguyen, T., Pan, H., Phan, S., Ying, F., Roe, B. A., Tochigi, J., Shimizu, Y., Minoshima, S. et al. (2000) The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome. Genomics 64, 277-285
27. Perkins, D. N., Pappin, D. J., Creasy, D. M. and Cottrell, J. S. (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 20, 3551-3567
28. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W. and Lipman, D. J. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25, 3389-3402
29. Akalal, D. B., Schein, C. H. and Nagle, G. T. (2004) Mollusk-derived growth factor and the new subfamily of adenosine deaminase-related growth factors. Curr. Pharm. Des. 10, 3893-3900
30. Farrugia, A. and Poulis, P. (2001) Intravenous immunoglobulin: regulatory perspectives on use and supply. Transfus. Med. 11, 63-74
31. Lin, X. (2004) Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131, 6009-6021
32. Meins, M., Burfeind, P., Motsch, S., Trappe, R., Bartmus, D., Langer, S., Speicher, M. R., Muhlendyck, H., Bartels, I. and Zoll, B. (2003) Partial trisomy of chromosome 22 resulting from an interstitial duplication of 22q11.2 in a child with typical cat eye syndrome. J. Med. Genet. 40, e62
33. Zurovec, M., Dolezal, T., Gazi, M., Pavlova, E. and Bryant, P. J. (2002) Adenosine deaminase-related growth factors stimulate cell proliferation in Drosophila by depleting extracellular adenosine. Proc. Natl. Acad. Sci. U.S.A. 99, 4403-4408
34. Dolezal, T., Dolezelova, E., Zurovec, M. and Bryant, P. J. (2005) A role for adenosine deaminase in Drosophila larval development. PLoS Biol. 3, e201
35. Hoffmann, J. A. and Reichhart, J. M. (2002) Drosophila innate immunity: an evolutionary perspective. Nat. Immunol. 3, 121-126
36. Sitkovsky, M. V., Lukashev, D., Apasov, S., Kojima, H., Koshiba, M., Caldwell, C., Ohta, A. and Thiel, M. (2004) Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors. Annu. Rev. Immunol. 22, 657-682
37. Stubbs, M., McSheehy, P. M., Griffiths, J. R. and Bashford, C. L. (2000) Causes and consequences of tumour acidity and implications for treatment. Mol. Med. Today 6, 15-19
38. Pollard, J. W. (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 4, 71-78
39. Jin, X., Shepherd, R. K., Duling, B. R. and Linden, J. (1997) Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation. J. Clin. Invest. 100, 2849-2857
40. Martin, M., Huguet, J., Centelles, J. J. and Franco, R. (1995) Expression of ecto-adenosine deaminase and CD26 in human T cells triggered by the TCR-CD3 complex. Possible role of adenosine deaminase as costimulatory molecule. J. Immunol. 155, 4630-4643
41. Myers, E. and Miller, W. (1988) Optimal alignments in linear space. CABIOS 4, 11-17
42. Bendtsen, J. D., Nielsen, H., von Heijne, G. and Brunak, S. (2004) Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol. 340, 783-795