Human N6-methyl-AMP/dAMP aminohydrolase (abacavir 5-monophosphate deaminase) is capable of metabolizing N6-substituted purine acyclic nucleoside phosphonates

Collection of Czechoslovak Chemical Communications

Volumn 73, Issue 2, 2008, Pages 275-291

  Schinkmanová, Markéta ^a   Votruba, Ivan ^a   Shibata, Riri ^b   Han, Bin ^b   Liu, Xiaohong ^b   Cihlar, Tomas ^b   Holý, Antonín ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b GILEAD SCIENCES   (United States)

Author keywords

2,6 diaminopurine; Abacavir 5 phosphate; Acyclic nucleoside phosphonates; cPrPMEDAP; Guanine; N6 methyl AMP aminohydrolase; Prodrugs

Indexed keywords

EID: 43049123187     PISSN: 00100765     EISSN: None     Source Type: Journal    
DOI: 10.1135/cccc20080275     Document Type: Article

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