"Click" dendrimers as anti-inflammatory agents: With insights into their binding from molecular modeling studies

Molecular Pharmaceutics

Volumn 10, Issue 6, 2013, Pages 2502-2508

  Neibert, Kevin ^a   Gosein, Varin ^a   Sharma, Anjali ^a   Khan, Mohidus ^a   Whitehead, Michael A ^a   Maysinger, Dusica ^a   Kakkar, Ashok ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

anti inflammatory; COX; dendrimers; iNOS; microglia; molecular modeling

Indexed keywords

ANTIINFLAMMATORY AGENT; CELECOXIB; CYCLOOXYGENASE 2; DENDRIMER; DG0 A DENDRIMER; DG1 A DENDRIMER; DG2 A DENDRIMER; IBUPROFEN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; COMPUTER MODEL; CONCENTRATION RESPONSE; DRUG CONFORMATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOSTIMULATION; IN VITRO STUDY; MICROGLIA; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR SIZE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CYCLOOXYGENASE 2; DENDRIMERS; LIPOPOLYSACCHARIDES; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II;

EID: 84878664140     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4000508     Document Type: Article

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