-
1
-
-
77951234285
-
Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics, and nanomedicine
-
Astruc D., Boisselier E., Ornelas C. Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics, and nanomedicine. Chem. Rev. 2010, 110:1857-1959.
-
(2010)
Chem. Rev.
, vol.110
, pp. 1857-1959
-
-
Astruc, D.1
Boisselier, E.2
Ornelas, C.3
-
2
-
-
28744443398
-
Dendrimers in biomedical applications-reflections on the field
-
Svenson S., Tomalia D.A. Dendrimers in biomedical applications-reflections on the field. Adv. Drug Deliv. Rev. 2005, 57:2106-2129.
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 2106-2129
-
-
Svenson, S.1
Tomalia, D.A.2
-
3
-
-
0028218595
-
Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy
-
Fréchet J.M. Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy. Science 1994, 263:1710-1715.
-
(1994)
Science
, vol.263
, pp. 1710-1715
-
-
Fréchet, J.M.1
-
4
-
-
78650697292
-
A synthetic "tour de force": well-defined multivalent and multimodal dendritic structures for biomedical applications
-
Röglin L., Lempens E.H., Meijer E.W. A synthetic "tour de force": well-defined multivalent and multimodal dendritic structures for biomedical applications. Angew. Chem. Int. Ed Engl. 2011, 50:102-112.
-
(2011)
Angew. Chem. Int. Ed Engl.
, vol.50
, pp. 102-112
-
-
Röglin, L.1
Lempens, E.H.2
Meijer, E.W.3
-
6
-
-
3743150592
-
Dendrimers in supramolecular chemistry: from molecular recognition to self-assembly
-
Zeng F., Zimmerman S.C. Dendrimers in supramolecular chemistry: from molecular recognition to self-assembly. Chem. Rev. 1997, 97:1681-1712.
-
(1997)
Chem. Rev.
, vol.97
, pp. 1681-1712
-
-
Zeng, F.1
Zimmerman, S.C.2
-
7
-
-
67650690627
-
Dendrimers as carriers for delivery of chemotherapeutic agents
-
Medina S.H., El-Sayed M.E. Dendrimers as carriers for delivery of chemotherapeutic agents. Chem. Rev. 2009, 109:3141-3157.
-
(2009)
Chem. Rev.
, vol.109
, pp. 3141-3157
-
-
Medina, S.H.1
El-Sayed, M.E.2
-
8
-
-
2342636314
-
Singlet oxygen generation via two-photon excited FRET
-
Dichtel W.R., Serin J.M., Edder C., Fréchet J.M., Matuszewski M., Tan L.S., Ohulchanskyy T.Y., Prasad P.N. Singlet oxygen generation via two-photon excited FRET. J. Am. Chem. Soc. 2004, 126:5380-5381.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 5380-5381
-
-
Dichtel, W.R.1
Serin, J.M.2
Edder, C.3
Fréchet, J.M.4
Matuszewski, M.5
Tan, L.S.6
Ohulchanskyy, T.Y.7
Prasad, P.N.8
-
9
-
-
52949130961
-
Current dendrimer applications in cancer diagnosis and therapy
-
Majoros I.J., Williams C.R., Baker J.R. Current dendrimer applications in cancer diagnosis and therapy. Curr. Top. Med. Chem. 2008, 8:1165-1179.
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, pp. 1165-1179
-
-
Majoros, I.J.1
Williams, C.R.2
Baker, J.R.3
-
10
-
-
80054756400
-
Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics
-
Godin B., Tasciotti E., Liu X., Serda R.E., Ferrari M. Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics. Acc. Chem. Res. 2011, 44:979-989.
-
(2011)
Acc. Chem. Res.
, vol.44
, pp. 979-989
-
-
Godin, B.1
Tasciotti, E.2
Liu, X.3
Serda, R.E.4
Ferrari, M.5
-
11
-
-
52949146356
-
Applications of dendrimers in tissue engineering
-
Joshi N., Grinstaff M. Applications of dendrimers in tissue engineering. Curr. Top. Med. Chem. 2008, 8:1225-1236.
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, pp. 1225-1236
-
-
Joshi, N.1
Grinstaff, M.2
-
12
-
-
28644434579
-
Designing dendrimers for biological applications
-
Lee C.C., MacKay J.A., Fréchet J.M., Szoka F.C. Designing dendrimers for biological applications. Nat. Biotechnol. 2005, 23:1517-1526.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1517-1526
-
-
Lee, C.C.1
MacKay, J.A.2
Fréchet, J.M.3
Szoka, F.C.4
-
13
-
-
81855165984
-
Dendrimers in biosensors: concept and applications
-
Satija J., Sai V.V.R., Mukherji S. Dendrimers in biosensors: concept and applications. J. Mater. Chem. 2011, 21:14367-14386.
-
(2011)
J. Mater. Chem.
, vol.21
, pp. 14367-14386
-
-
Satija, J.1
Sai, V.V.R.2
Mukherji, S.3
-
14
-
-
79960235638
-
Ferrocene-peptido conjugates: from synthesis to sensory applications
-
Martić S., Labib M., Shipman P.O., Kraatz H.B. Ferrocene-peptido conjugates: from synthesis to sensory applications. Dalton Trans. 2011, 40:7264-7290.
-
(2011)
Dalton Trans.
, vol.40
, pp. 7264-7290
-
-
Martić, S.1
Labib, M.2
Shipman, P.O.3
Kraatz, H.B.4
-
15
-
-
41849134718
-
Kilogram-scale synthesis of a second generation dendrimer based on 1,3,5-triazine using green and industrially compatible methods with a single chromatographic step
-
Chouai A., Simanek E.E. Kilogram-scale synthesis of a second generation dendrimer based on 1,3,5-triazine using green and industrially compatible methods with a single chromatographic step. J. Org. Chem. 2008, 73:2357-2366.
-
(2008)
J. Org. Chem.
, vol.73
, pp. 2357-2366
-
-
Chouai, A.1
Simanek, E.E.2
-
16
-
-
70349291544
-
Large scale, green synthesis of a generation-1 melamine (triazine) dendrimer
-
Chouai A., Venditto V.J., Simanek E.E., Vanderplas B.C., Ragan J.A. Large scale, green synthesis of a generation-1 melamine (triazine) dendrimer. Organic Synth. 2009, 86:151.
-
(2009)
Organic Synth.
, vol.86
, pp. 151
-
-
Chouai, A.1
Venditto, V.J.2
Simanek, E.E.3
Vanderplas, B.C.4
Ragan, J.A.5
-
17
-
-
70349296273
-
Synthesis of 2-[3,3'-di-(tert-butoxycarbonyl)-aminodipropylamine]-4,6,-dichloro-1,3,5-triazine as a monomer and 1,3,5-[tris-piperazine]-triazine as a core for the large scale synthesis of melamine (triazine) dendrimers
-
Chouai A., Venditto V.J., Simanek E.E., McDermott R.E., Ragan J.A. Synthesis of 2-[3,3'-di-(tert-butoxycarbonyl)-aminodipropylamine]-4,6,-dichloro-1,3,5-triazine as a monomer and 1,3,5-[tris-piperazine]-triazine as a core for the large scale synthesis of melamine (triazine) dendrimers. Organic Synth. 2009, 86:141-150.
-
(2009)
Organic Synth.
, vol.86
, pp. 141-150
-
-
Chouai, A.1
Venditto, V.J.2
Simanek, E.E.3
McDermott, R.E.4
Ragan, J.A.5
-
18
-
-
77949802553
-
Synthesis of odd generation triazine dendrimers using a divergent, macromonomer approach
-
Lim J., Mintzer M.A., Perez L.M., Simanek E.E. Synthesis of odd generation triazine dendrimers using a divergent, macromonomer approach. Org. Lett. 2010, 12:1148-1151.
-
(2010)
Org. Lett.
, vol.12
, pp. 1148-1151
-
-
Lim, J.1
Mintzer, M.A.2
Perez, L.M.3
Simanek, E.E.4
-
19
-
-
84856492212
-
Experimental and computational evidence for an inversion in guest capacity in high-generation triazine dendrimer hosts
-
Lim J., Pavan G.M., Annunziata O., Simanek E.E. Experimental and computational evidence for an inversion in guest capacity in high-generation triazine dendrimer hosts. J. Am. Chem. Soc. 2012, 134:1942-1945.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 1942-1945
-
-
Lim, J.1
Pavan, G.M.2
Annunziata, O.3
Simanek, E.E.4
-
20
-
-
77952029410
-
The 8 year thicket of triazine dendrimers: strategies, targets and applications
-
Simanek E.E., Abdou H., Lalwani S., Lim J., Mintzer M., Venditto V.J., Vittur B. The 8 year thicket of triazine dendrimers: strategies, targets and applications. Proc. R. Soc. A 2010, 466:1445-1468.
-
(2010)
Proc. R. Soc. A
, vol.466
, pp. 1445-1468
-
-
Simanek, E.E.1
Abdou, H.2
Lalwani, S.3
Lim, J.4
Mintzer, M.5
Venditto, V.J.6
Vittur, B.7
-
21
-
-
38349059600
-
Identification of diamine linkers with differing reactivity and their application in the synthesis of melamine dendrimers
-
Moreno K.X., Simanek E.E. Identification of diamine linkers with differing reactivity and their application in the synthesis of melamine dendrimers. Tetrahedron Lett. 2008, 49:1152-1154.
-
(2008)
Tetrahedron Lett.
, vol.49
, pp. 1152-1154
-
-
Moreno, K.X.1
Simanek, E.E.2
-
22
-
-
0141629661
-
Chemoselective building blocks for dendrimers from relative reactivity data
-
Steffensen M.B., Simanek E.E. Chemoselective building blocks for dendrimers from relative reactivity data. Org. Lett. 2003, 5:2359-2361.
-
(2003)
Org. Lett.
, vol.5
, pp. 2359-2361
-
-
Steffensen, M.B.1
Simanek, E.E.2
-
23
-
-
47249144700
-
Conformational analysis of triazine dendrimers: using NMR spectroscopy to probe the choreography of a dendrimer's dance
-
Moreno K.X., Simanek E.E. Conformational analysis of triazine dendrimers: using NMR spectroscopy to probe the choreography of a dendrimer's dance. Macromolecules 2008, 41:4108-4114.
-
(2008)
Macromolecules
, vol.41
, pp. 4108-4114
-
-
Moreno, K.X.1
Simanek, E.E.2
-
24
-
-
33744824083
-
Dendrimers based on [1,3,5]-triazines
-
Steffensen M.B., Hollink E., Kuschel F., Bauer M., Simanek E.E. Dendrimers based on [1,3,5]-triazines. J. Polym. Sci. A 2006, 44:3411-3433.
-
(2006)
J. Polym. Sci. A
, vol.44
, pp. 3411-3433
-
-
Steffensen, M.B.1
Hollink, E.2
Kuschel, F.3
Bauer, M.4
Simanek, E.E.5
-
25
-
-
0001620656
-
Dendrimers based on melamine. Divergent and orthogonal, convergent synthesis of a G3 dendrimer
-
Zhang W., Simanek E.E. Dendrimers based on melamine. Divergent and orthogonal, convergent synthesis of a G3 dendrimer. Org. Lett. 2000, 2:843-845.
-
(2000)
Org. Lett.
, vol.2
, pp. 843-845
-
-
Zhang, W.1
Simanek, E.E.2
-
26
-
-
0035913710
-
Orthogonal, convergent syntheses of dendrimers based on melamine with one or two unique surface sites for manipulation
-
Zhang W., Nowlan D.T., Thomson L.M., Lackowski W.M., Simanek E.E. Orthogonal, convergent syntheses of dendrimers based on melamine with one or two unique surface sites for manipulation. J. Am. Chem. Soc. 2001, 123:8914-8922.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 8914-8922
-
-
Zhang, W.1
Nowlan, D.T.2
Thomson, L.M.3
Lackowski, W.M.4
Simanek, E.E.5
-
27
-
-
23944438414
-
Toward the next-generation drug delivery vehicle: synthesis of a dendrimer with four orthogonally reactive groups
-
Lim J., Simanek E.E. Toward the next-generation drug delivery vehicle: synthesis of a dendrimer with four orthogonally reactive groups. Mol. Pharmaceutics 2005, 2:273-277.
-
(2005)
Mol. Pharmaceutics
, vol.2
, pp. 273-277
-
-
Lim, J.1
Simanek, E.E.2
-
28
-
-
6044260213
-
Synthesis and manipulation of orthogonally protected dendrimers: building blocks for library synthesis
-
Steffensen M.B., Simanek E.E. Synthesis and manipulation of orthogonally protected dendrimers: building blocks for library synthesis. Angew. Chem. Int. Ed. 2004, 43:5178-5180.
-
(2004)
Angew. Chem. Int. Ed.
, vol.43
, pp. 5178-5180
-
-
Steffensen, M.B.1
Simanek, E.E.2
-
29
-
-
37549049413
-
Triazine dendrimers with orthogonally protected amines on the periphery. Masking amines with Dde and BOC groups provides an alternative to carrying protected alcohols and disulfides through an iterative synthesis
-
Umali A.P., Crampton H.L., Simanek E.E. Triazine dendrimers with orthogonally protected amines on the periphery. Masking amines with Dde and BOC groups provides an alternative to carrying protected alcohols and disulfides through an iterative synthesis. J. Org. Chem. 2007, 72:9866-9874.
-
(2007)
J. Org. Chem.
, vol.72
, pp. 9866-9874
-
-
Umali, A.P.1
Crampton, H.L.2
Simanek, E.E.3
-
30
-
-
0038262870
-
Thiol-disulfide exchange yields multivalent dendrimers of melamine
-
Umali A.P., Simanek E.E. Thiol-disulfide exchange yields multivalent dendrimers of melamine. Org. Lett. 2003, 5:1245-1247.
-
(2003)
Org. Lett.
, vol.5
, pp. 1245-1247
-
-
Umali, A.P.1
Simanek, E.E.2
-
31
-
-
0242515748
-
Evaluation of multivalent dendrimers based on melamine: kinetics of thiol-disulfide exchange depends on the structure of the dendrimer
-
Zhang W., Tichy S.E., Perez L.M., Maria G.C., Lindahl P.A., Simanek E.E. Evaluation of multivalent dendrimers based on melamine: kinetics of thiol-disulfide exchange depends on the structure of the dendrimer. J. Am. Chem. Soc. 2003, 125:5086-5094.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 5086-5094
-
-
Zhang, W.1
Tichy, S.E.2
Perez, L.M.3
Maria, G.C.4
Lindahl, P.A.5
Simanek, E.E.6
-
32
-
-
34447136351
-
A divergent route towards single-chemical entity triazine dendrimers with opportunities for structural diversity
-
Crampton H., Hollink E., Perez L.M., Simanek E.E. A divergent route towards single-chemical entity triazine dendrimers with opportunities for structural diversity. New J. Chem. 2007, 31:1283-1290.
-
(2007)
New J. Chem.
, vol.31
, pp. 1283-1290
-
-
Crampton, H.1
Hollink, E.2
Perez, L.M.3
Simanek, E.E.4
-
33
-
-
33745711825
-
A divergent route to diversity in macromolecules
-
Hollink E., Simanek E.E. A divergent route to diversity in macromolecules. Org. Lett. 2006, 8:2293-2295.
-
(2006)
Org. Lett.
, vol.8
, pp. 2293-2295
-
-
Hollink, E.1
Simanek, E.E.2
-
34
-
-
76949083604
-
Divergent synthesis of triazine dendrimers using a trimethylene-dipiperidine linker that increases efficiency, simplifies analysis, and improves product solubility
-
Mintzer M.A., Perez L.M., Simanek E.E. Divergent synthesis of triazine dendrimers using a trimethylene-dipiperidine linker that increases efficiency, simplifies analysis, and improves product solubility. Tetrahedron Lett. 2010, 51:1631-1634.
-
(2010)
Tetrahedron Lett.
, vol.51
, pp. 1631-1634
-
-
Mintzer, M.A.1
Perez, L.M.2
Simanek, E.E.3
-
35
-
-
38749098734
-
Synthesis of water-soluble dendrimers based on melamine bearing 16 paclitaxel groups
-
Lim J., Simanek E.E. Synthesis of water-soluble dendrimers based on melamine bearing 16 paclitaxel groups. Org. Lett. 2008, 10:201-204.
-
(2008)
Org. Lett.
, vol.10
, pp. 201-204
-
-
Lim, J.1
Simanek, E.E.2
-
36
-
-
71249089119
-
Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages
-
Lim J., Chouai A., Lo S.T., Liu W., Sun X., Simanek E.E. Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages. Bioconjugate Chem. 2009, 20:2154-2161.
-
(2009)
Bioconjugate Chem.
, vol.20
, pp. 2154-2161
-
-
Lim, J.1
Chouai, A.2
Lo, S.T.3
Liu, W.4
Sun, X.5
Simanek, E.E.6
-
37
-
-
77955247075
-
Biological assessment of triazine dendrimer: toxicological profiles, solution behavior, biodistribution, drug release and efficacy in a PEGylated, paclitaxel construct
-
Lo S.T., Stern S., Clogston J.D., Zheng J., Adiseshaiah P.P., Dobrovolskaia M., Lim J., Patri A.K., Sun X., Simanek E.E. Biological assessment of triazine dendrimer: toxicological profiles, solution behavior, biodistribution, drug release and efficacy in a PEGylated, paclitaxel construct. Mol. Pharmaceutics 2010, 7:993-1006.
-
(2010)
Mol. Pharmaceutics
, vol.7
, pp. 993-1006
-
-
Lo, S.T.1
Stern, S.2
Clogston, J.D.3
Zheng, J.4
Adiseshaiah, P.P.5
Dobrovolskaia, M.6
Lim, J.7
Patri, A.K.8
Sun, X.9
Simanek, E.E.10
-
38
-
-
84863229418
-
Antitumor activity and molecular dynamics simulations of paclitaxel-laden triazine dendrimers
-
Lim J., Lo S.T., Hill S., Pavan G.M., Sun X., Simanek E.E. Antitumor activity and molecular dynamics simulations of paclitaxel-laden triazine dendrimers. Mol. Pharmaceutics 2012, 9:404-412.
-
(2012)
Mol. Pharmaceutics
, vol.9
, pp. 404-412
-
-
Lim, J.1
Lo, S.T.2
Hill, S.3
Pavan, G.M.4
Sun, X.5
Simanek, E.E.6
-
39
-
-
77955412648
-
Synthesis and characterization of a triazine dendrimer that sequesters iron(III) using 12 desferrioxamine B groups
-
Lim J., Venditto V.J., Simanek E.E. Synthesis and characterization of a triazine dendrimer that sequesters iron(III) using 12 desferrioxamine B groups. Bioorg. Med. Chem. 2010, 18:5749-5753.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 5749-5753
-
-
Lim, J.1
Venditto, V.J.2
Simanek, E.E.3
-
40
-
-
84857191662
-
Encapsulation of a concanavalin A/dendrimer glucose sensing assay within microporated poly (ethylene glycol) microspheres
-
Cummin B.M., Lim J., Simanek E.E., Pishko M.V., Coté G.L. Encapsulation of a concanavalin A/dendrimer glucose sensing assay within microporated poly (ethylene glycol) microspheres. Biomed. Opt. Express 2011, 2:1243-1257.
-
(2011)
Biomed. Opt. Express
, vol.2
, pp. 1243-1257
-
-
Cummin, B.M.1
Lim, J.2
Simanek, E.E.3
Pishko, M.V.4
Coté, G.L.5
-
41
-
-
70349266134
-
Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles
-
Venditto V.J., Allred K., Allred C.D., Simanek E.E. Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles. Chem. Commun. 2009, 7:5541-5542.
-
(2009)
Chem. Commun.
, vol.7
, pp. 5541-5542
-
-
Venditto, V.J.1
Allred, K.2
Allred, C.D.3
Simanek, E.E.4
-
42
-
-
28744445460
-
Dendrimer biocompatibility and toxicity
-
Duncan R., Izzo L. Dendrimer biocompatibility and toxicity. Adv. Drug Deliv. Rev. 2005, 57:2215-2237.
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 2215-2237
-
-
Duncan, R.1
Izzo, L.2
-
43
-
-
4043103282
-
Cytotoxicty, hemolysis and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery
-
Chen H.-T., Neerman M.F., Parrish A.R., Simanek E.E. Cytotoxicty, hemolysis and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery. J. Am. Chem. Soc. 2004, 126:10044-10048.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 10044-10048
-
-
Chen, H.-T.1
Neerman, M.F.2
Parrish, A.R.3
Simanek, E.E.4
-
44
-
-
20044396385
-
Reduction of drug toxicity using dendrimers based on melamine
-
Neerman M.F., Chen H.-T., Parrish A.R., Simanek E.E. Reduction of drug toxicity using dendrimers based on melamine. Mol. Pharmaceutics 2004, 1:390-393.
-
(2004)
Mol. Pharmaceutics
, vol.1
, pp. 390-393
-
-
Neerman, M.F.1
Chen, H.-T.2
Parrish, A.R.3
Simanek, E.E.4
-
45
-
-
3543116767
-
In vitro and in vivo evaluation of a melamine dendrimer as a vehicle for drug delivery
-
Neerman M.F., Zhang W., Parrish A.R., Simanek E.E. In vitro and in vivo evaluation of a melamine dendrimer as a vehicle for drug delivery. Int. J. Pharm. 2004, 281:129-132.
-
(2004)
Int. J. Pharm.
, vol.281
, pp. 129-132
-
-
Neerman, M.F.1
Zhang, W.2
Parrish, A.R.3
Simanek, E.E.4
-
46
-
-
13444303908
-
Biological evaluation of dendrimers based on melamine
-
Neerman M.F., Umali A.P., Chen H.-T., Waghela S.D., Parrish A.R., Simanek E.E. Biological evaluation of dendrimers based on melamine. J. Drug Del. Sci. Tech. 2005, 15:31-40.
-
(2005)
J. Drug Del. Sci. Tech.
, vol.15
, pp. 31-40
-
-
Neerman, M.F.1
Umali, A.P.2
Chen, H.-T.3
Waghela, S.D.4
Parrish, A.R.5
Simanek, E.E.6
-
47
-
-
0242509060
-
Triazine dendrimers for drug delivery: evaluation of solubilization properties, activity in cell culture, and in vivo toxicity of a candidate vehicle
-
Zhang W., Jiang J., Qin C., Thomson L.M., Parrish A.R., Safe S.H., Simanek E.E. Triazine dendrimers for drug delivery: evaluation of solubilization properties, activity in cell culture, and in vivo toxicity of a candidate vehicle. Supramol. Chem. 2003, 15:607-615.
-
(2003)
Supramol. Chem.
, vol.15
, pp. 607-615
-
-
Zhang, W.1
Jiang, J.2
Qin, C.3
Thomson, L.M.4
Parrish, A.R.5
Safe, S.H.6
Simanek, E.E.7
-
48
-
-
18844370132
-
Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture
-
Gillies E.R., Dy E., Fréchet J.M.J., Szoka F.C. Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture. Mol. Pharmaceutics 2005, 2:129-138.
-
(2005)
Mol. Pharmaceutics
, vol.2
, pp. 129-138
-
-
Gillies, E.R.1
Dy, E.2
Fréchet, J.M.J.3
Szoka, F.C.4
-
49
-
-
51049092122
-
The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers
-
Lim J., Guo Y., Rostollan C.L., Stanfield J., Hsieh J.-T., Sun X., Simanek E.E. The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers. Mol. Pharmaceutics 2008, 5:540-547.
-
(2008)
Mol. Pharmaceutics
, vol.5
, pp. 540-547
-
-
Lim, J.1
Guo, Y.2
Rostollan, C.L.3
Stanfield, J.4
Hsieh, J.-T.5
Sun, X.6
Simanek, E.E.7
-
50
-
-
46449100402
-
The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of PEGylated poly l-lysine dendrimers
-
Kaminskas L.M., Boyd B.J., Karellas P., Krippner G.Y., Lessene R., Kelly B., Porter C.J.H. The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of PEGylated poly l-lysine dendrimers. Mol. Pharmaceutics 2008, 5:449-463.
-
(2008)
Mol. Pharmaceutics
, vol.5
, pp. 449-463
-
-
Kaminskas, L.M.1
Boyd, B.J.2
Karellas, P.3
Krippner, G.Y.4
Lessene, R.5
Kelly, B.6
Porter, C.J.H.7
-
51
-
-
0242288519
-
Macromolecular therapeutics: advantages and prospects with special emphasis on solid tumour targeting
-
Greish K., Fang J., Inutsuka T., Nagamitsu A., Maeda H. Macromolecular therapeutics: advantages and prospects with special emphasis on solid tumour targeting. Clin. Pharmacokinet. 2003, 42:1089-1105.
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 1089-1105
-
-
Greish, K.1
Fang, J.2
Inutsuka, T.3
Nagamitsu, A.4
Maeda, H.5
-
52
-
-
79953774326
-
Non-viral nucleic acid delivery: key challenges and future directions
-
Elsabahy M., Nazarali A., Foldvari M. Non-viral nucleic acid delivery: key challenges and future directions. Curr. Drug Deliv. 2011, 8:235-244.
-
(2011)
Curr. Drug Deliv.
, vol.8
, pp. 235-244
-
-
Elsabahy, M.1
Nazarali, A.2
Foldvari, M.3
-
54
-
-
64549134676
-
Nonviral vectors for gene delivery
-
Mintzer M.A., Simanek E.E. Nonviral vectors for gene delivery. Chem. Rev. 2009, 109:259-302.
-
(2009)
Chem. Rev.
, vol.109
, pp. 259-302
-
-
Mintzer, M.A.1
Simanek, E.E.2
-
55
-
-
80052882155
-
Advances in gene delivery systems
-
Kamimura K., Suda T., Zhang G., Liu D. Advances in gene delivery systems. Pharmaceut. Med. 2011, 25:293-306.
-
(2011)
Pharmaceut. Med.
, vol.25
, pp. 293-306
-
-
Kamimura, K.1
Suda, T.2
Zhang, G.3
Liu, D.4
-
56
-
-
79952149658
-
The inside out of lentiviral vectors
-
Durand S., Cimarelli A. The inside out of lentiviral vectors. Viruses 2011, 3:132-159.
-
(2011)
Viruses
, vol.3
, pp. 132-159
-
-
Durand, S.1
Cimarelli, A.2
-
57
-
-
77953541881
-
DNA nanomedicine: engineering DNA as a polymer for therapeutic and diagnostic applications
-
Campolongo M.J., Tan S.J., Xu J., Luo D. DNA nanomedicine: engineering DNA as a polymer for therapeutic and diagnostic applications. Adv. Drug Deliv. Rev. 2010, 62:606-616.
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 606-616
-
-
Campolongo, M.J.1
Tan, S.J.2
Xu, J.3
Luo, D.4
-
58
-
-
70049113326
-
Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency
-
Mintzer M.A., Merkel O.M., Kissel T., Simanek E.E. Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency. New J. Chem. 2009, 33:1918-1925.
-
(2009)
New J. Chem.
, vol.33
, pp. 1918-1925
-
-
Mintzer, M.A.1
Merkel, O.M.2
Kissel, T.3
Simanek, E.E.4
-
59
-
-
70349192989
-
Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity
-
Merkel O.M., Mintzer M.A., Sitterberg J., Bakowsky U., Simanek E.E., Kissel T. Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity. Bioconjugate Chem. 2009, 20:1799-1806.
-
(2009)
Bioconjugate Chem.
, vol.20
, pp. 1799-1806
-
-
Merkel, O.M.1
Mintzer, M.A.2
Sitterberg, J.3
Bakowsky, U.4
Simanek, E.E.5
Kissel, T.6
-
60
-
-
77955240438
-
Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity
-
Merkel O.M., Mintzer M.A., Librizzi D., Samsonova O., Dicke T., Sproat B., Garn H., Barth P.J., Simanek E.E., Kissel T. Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity. Mol. Pharmaceutics 2010, 7:969-983.
-
(2010)
Mol. Pharmaceutics
, vol.7
, pp. 969-983
-
-
Merkel, O.M.1
Mintzer, M.A.2
Librizzi, D.3
Samsonova, O.4
Dicke, T.5
Sproat, B.6
Garn, H.7
Barth, P.J.8
Simanek, E.E.9
Kissel, T.10
-
61
-
-
77950102895
-
Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers
-
Pavan G.M., Mintzer M.A., Simanek E.E., Merkel O.M., Kissel T., Danani A. Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers. Biomacromolecules 2010, 11:721-730.
-
(2010)
Biomacromolecules
, vol.11
, pp. 721-730
-
-
Pavan, G.M.1
Mintzer, M.A.2
Simanek, E.E.3
Merkel, O.M.4
Kissel, T.5
Danani, A.6
-
62
-
-
79960091210
-
Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems
-
Merkel O.M., Zheng M., Mintzer M.A., Pavan G.M., Librizzi D., Maly M., Höffken H., Danani A., Simanek E.E., Kissel T. Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems. J. Control. Release 2011, 153:23-33.
-
(2011)
J. Control. Release
, vol.153
, pp. 23-33
-
-
Merkel, O.M.1
Zheng, M.2
Mintzer, M.A.3
Pavan, G.M.4
Librizzi, D.5
Maly, M.6
Höffken, H.7
Danani, A.8
Simanek, E.E.9
Kissel, T.10
-
63
-
-
0036220676
-
Progress in gene delivery by cationic lipids: guanidinium-cholesterol-based systems as an example
-
Aissaoui A., Oudrhiri N., Petit L., Hauchecorne M., Kan E., Sainlos M., Julia S., Navarro J., Vigneron J.P., Lehn J.M., Lehn P. Progress in gene delivery by cationic lipids: guanidinium-cholesterol-based systems as an example. Curr. Drug Targets 2002, 3:1-16.
-
(2002)
Curr. Drug Targets
, vol.3
, pp. 1-16
-
-
Aissaoui, A.1
Oudrhiri, N.2
Petit, L.3
Hauchecorne, M.4
Kan, E.5
Sainlos, M.6
Julia, S.7
Navarro, J.8
Vigneron, J.P.9
Lehn, J.M.10
Lehn, P.11
-
64
-
-
59549093153
-
Polycationic phosphorus dendrimers: synthesis, characterization, study of cytotoxicity, complexation of DNA, and transfection experiments
-
Padié C., Maszewska M., Majchrzak K., Nawrot B., Caminade A.M., Majoral J.P. Polycationic phosphorus dendrimers: synthesis, characterization, study of cytotoxicity, complexation of DNA, and transfection experiments. New J. Chem. 2009, 33:318-326.
-
(2009)
New J. Chem.
, vol.33
, pp. 318-326
-
-
Padié, C.1
Maszewska, M.2
Majchrzak, K.3
Nawrot, B.4
Caminade, A.M.5
Majoral, J.P.6
-
65
-
-
67650090818
-
Synthesis and characterization of anionic triazine dendrimers with a labile disulfide core
-
Zhang W., Lalwani S., Chouai A., Simanek E.E. Synthesis and characterization of anionic triazine dendrimers with a labile disulfide core. Isr. J. Chem. 2009, 49:23-30.
-
(2009)
Isr. J. Chem.
, vol.49
, pp. 23-30
-
-
Zhang, W.1
Lalwani, S.2
Chouai, A.3
Simanek, E.E.4
-
66
-
-
25144476858
-
Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy
-
Scripture C.D., Figg W.D., Sparreboom A. Paclitaxel chemotherapy: from empiricism to a mechanism-based formulation strategy. Ther. Clin. Risk Manag. 2005, 1:107-114.
-
(2005)
Ther. Clin. Risk Manag.
, vol.1
, pp. 107-114
-
-
Scripture, C.D.1
Figg, W.D.2
Sparreboom, A.3
-
67
-
-
2942562025
-
Docetaxel and paclitaxel in the treatment of breast cancer: a review of clinical experience
-
Crown J., O'Leary M., Ooi W.S. Docetaxel and paclitaxel in the treatment of breast cancer: a review of clinical experience. Oncologist 2004, 9:24-32.
-
(2004)
Oncologist
, vol.9
, pp. 24-32
-
-
Crown, J.1
O'Leary, M.2
Ooi, W.S.3
-
68
-
-
79551631275
-
Haque, Advances in nano drugs for cancer chemotherapy
-
Ali I., Rahis-Uddin K., Salim M.A., Rather W.A., Wani A. Haque, Advances in nano drugs for cancer chemotherapy. Curr. Cancer Drug Targets 2011, 11:135-146.
-
(2011)
Curr. Cancer Drug Targets
, vol.11
, pp. 135-146
-
-
Ali, I.1
Rahis-Uddin, K.2
Salim, M.A.3
Rather, W.A.4
Wani, A.5
-
69
-
-
38949108587
-
Recent developments in taxane drug delivery
-
Safavy A. Recent developments in taxane drug delivery. Curr. Drug Deliv. 2008, 5:42-54.
-
(2008)
Curr. Drug Deliv.
, vol.5
, pp. 42-54
-
-
Safavy, A.1
-
70
-
-
38049079353
-
Phase II study of weekly albumin-bound paclitaxel for patients with metastatic breast cancer heavily pretreated with taxanes
-
Blum J.L., Savin M.A., Edelman G., Pippen J., Robert N.J., Geister B.V., Kirby R.L., Clawson A., O'Shaughnessy J.A. Phase II study of weekly albumin-bound paclitaxel for patients with metastatic breast cancer heavily pretreated with taxanes. Clin. Breast Cancer 2007, 7:850-856.
-
(2007)
Clin. Breast Cancer
, vol.7
, pp. 850-856
-
-
Blum, J.L.1
Savin, M.A.2
Edelman, G.3
Pippen, J.4
Robert, N.J.5
Geister, B.V.6
Kirby, R.L.7
Clawson, A.8
O'Shaughnessy, J.A.9
-
71
-
-
42649132499
-
Protein nanoparticles as drug carriers in clinical medicine
-
Hawkins M.J., Soon-Shiong P., Desai N. Protein nanoparticles as drug carriers in clinical medicine. Adv. Drug Deliv. Rev. 2008, 60:876-885.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 876-885
-
-
Hawkins, M.J.1
Soon-Shiong, P.2
Desai, N.3
-
72
-
-
34247629652
-
Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer
-
Bonomi P. Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer. Expert Rev. Anticancer Ther. 2007, 7:415-422.
-
(2007)
Expert Rev. Anticancer Ther.
, vol.7
, pp. 415-422
-
-
Bonomi, P.1
-
73
-
-
77649190943
-
Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane
-
Feng Z., Zhao G., Yu L., Gough D., Howell S.B. Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane. Cancer Chemother. Pharmacol. 2010, 65:923-930.
-
(2010)
Cancer Chemother. Pharmacol.
, vol.65
, pp. 923-930
-
-
Feng, Z.1
Zhao, G.2
Yu, L.3
Gough, D.4
Howell, S.B.5
-
74
-
-
0032169909
-
Camptothecins: a review of their development and schedules of administration
-
O'Leary J., Muggia F.M. Camptothecins: a review of their development and schedules of administration. Eur. J. Cancer 1998, 34:1500-1508.
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 1500-1508
-
-
O'Leary, J.1
Muggia, F.M.2
-
76
-
-
33947697200
-
Chelation therapy for iron overload
-
Barton J.C. Chelation therapy for iron overload. Curr. Gastroenterol. Rep. 2007, 9:74-82.
-
(2007)
Curr. Gastroenterol. Rep.
, vol.9
, pp. 74-82
-
-
Barton, J.C.1
-
77
-
-
27744544284
-
Advances in iron overload therapies. prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NA11 and their combinations
-
Kontoghiorghes G.J., Eracleous E., Economides C., Kolnagou A. Advances in iron overload therapies. prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NA11 and their combinations. Curr. Med. Chem. 2005, 12:2663-2681.
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 2663-2681
-
-
Kontoghiorghes, G.J.1
Eracleous, E.2
Economides, C.3
Kolnagou, A.4
-
78
-
-
0024802647
-
Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers
-
Hallaway P.E., Eaton J.W., Panter S.S., Hedlund B.E. Modulation of deferoxamine toxicity and clearance by covalent attachment to biocompatible polymers. Proc. Natl. Acad. Sci. U. S. A. 1989, 86:10108-10112.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 10108-10112
-
-
Hallaway, P.E.1
Eaton, J.W.2
Panter, S.S.3
Hedlund, B.E.4
-
79
-
-
3542993234
-
Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation
-
Shaunak S., Thomas S., Gianasi E., Godwin A., Jones E., Teo I., Mireskandari K., Luthert P., Duncan R., Patterson S., Khaw P., Brocchini S. Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation. Nat. Biotechnol. 2004, 22:977-984.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 977-984
-
-
Shaunak, S.1
Thomas, S.2
Gianasi, E.3
Godwin, A.4
Jones, E.5
Teo, I.6
Mireskandari, K.7
Luthert, P.8
Duncan, R.9
Patterson, S.10
Khaw, P.11
Brocchini, S.12
-
80
-
-
80052967040
-
Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex
-
Barata T., Teo I., Lalwani S., Simanek E.E., Zloh M., Shaunak S. Computational design principles for bioactive dendrimer based constructs as antagonists of the TLR4-MD-2-LPS complex. Biomaterials 2011, 32:8702-8711.
-
(2011)
Biomaterials
, vol.32
, pp. 8702-8711
-
-
Barata, T.1
Teo, I.2
Lalwani, S.3
Simanek, E.E.4
Zloh, M.5
Shaunak, S.6
-
81
-
-
4344679385
-
Fluorescence glucose detection: advances toward the ideal in vivo biosensor
-
Moschou E.A., Sharma B.V., Deo S.K., Daunert S. Fluorescence glucose detection: advances toward the ideal in vivo biosensor. J. Fluoresc. 2004, 14:535-547.
-
(2004)
J. Fluoresc.
, vol.14
, pp. 535-547
-
-
Moschou, E.A.1
Sharma, B.V.2
Deo, S.K.3
Daunert, S.4
-
82
-
-
84857191662
-
Encapsulation of a Concanavalin A/dendrimer glucose sensing assay within microporated poly (ethylene glycol) microspheres
-
Cummin B.M., Lim J., Simanek E.E., Pishko M.V., Coté G.L. Encapsulation of a Concanavalin A/dendrimer glucose sensing assay within microporated poly (ethylene glycol) microspheres. Biomed. Opt. Express 2011, 2:1243-1257.
-
(2011)
Biomed. Opt. Express
, vol.2
, pp. 1243-1257
-
-
Cummin, B.M.1
Lim, J.2
Simanek, E.E.3
Pishko, M.V.4
Coté, G.L.5
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