Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro

Molecular Pharmaceutics

Volumn 9, Issue 3, 2012, Pages 382-393

  Dobrovolskaia, Marina A ^a   Patri, Anil K ^a   Simak, Jan ^b   Hall, Jennifer B ^a   Semberova, Jana ^b   De Paoli Lacerda, Silvia H ^b   McNeil, Scott E ^a  

^a SAIC FREDERICK INC   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

activation; aggregation; blood; coagulation; dendrimers; nanomaterials; nanomedicine; nanoparticles; PAMAM dendrimers; platelets; thrombocyte; thrombogenicity

Indexed keywords

DENDRIMER; NANOPARTICLE; POLYAMIDOAMINE;

ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE DAMAGE; NANOPHARMACEUTICS; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE CHARGE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE;

BLOOD PLATELETS; DENDRIMERS; FLOW CYTOMETRY; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PARTICLE SIZE; PLATELET AGGREGATION;

EID: 84858042094     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200463e     Document Type: Article

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