How to study dendrimers and dendriplexes III. Biodistribution, pharmacokinetics and toxicity in vivo

Journal of Controlled Release

Volumn 181, Issue 1, 2014, Pages 40-52

  Shcharbin, Dzmitry ^a   Janaszewska, Anna ^b   Klajnert Maculewicz, Barbara ^b   Ziemba, Barbara ^b   Dzmitruk, Volha ^a   Halets, Inessa ^a   Loznikova, Svetlana ^a   Shcharbina, Natallia ^c   Milowska, Katarzyna ^b   Ionov, Maksim ^b   Shakhbazau, Antos ^d   Bryszewska, Maria ^b  

^a INSTITUTE OF PHOTOBIOLOGY   (Belarus)

^b UNIVERSITY OF LODZ   (Poland)

^c Ministry of Health of the Republic of Belarus   (Belarus)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

Biodistribution; Dendrimer; Dendriplex; In vivo; Pharmacokinetics; Toxicity

Indexed keywords

CHEMICAL MODIFICATION; DENDRIMERS; GENE THERAPY; MAMMALS; NUCLEIC ACIDS; PHARMACOKINETICS; TOXICITY;

BIODISTRIBUTIONS; CYTOTOXIC EFFECTS; DENDRIPLEXES; HUMAN GENE THERAPY; IN-VIVO; IRREVERSIBLE DAMAGE; THERAPEUTIC AGENTS; UNDESIRABLE EFFECTS;

FUNCTIONAL POLYMERS;

DENDRIMER; DENDRIPLEX; DOXORUBICIN; MACROGOL; MELAMINE; NUCLEIC ACID; PHOSPHORUS; POLYAMIDOAMINE; POLYESTER; POLYETHYLENEIMINE; POLYLYSINE; SULFADIAZINE; TRANSFERRIN; TRIAZINE; UNCLASSIFIED DRUG; CATION; DRUG CARRIER; PAMAM STARBURST;

BIOTINYLATION; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CLEARANCE; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG TOXICITY; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; GUINEA PIG; HEART INJURY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY INJURY; LIVER INJURY; NONHUMAN; PANCREAS INJURY; PRIORITY JOURNAL; RABBIT; REVIEW; ANIMAL; CHEMISTRY; GENE TRANSFER; MOUSE; RAT; TISSUE DISTRIBUTION; TOXICITY;

ANIMALS; CATIONS; DENDRIMERS; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; GUINEA PIGS; MICE; NUCLEIC ACIDS; RABBITS; RATS; TISSUE DISTRIBUTION;

EID: 84896535996     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.02.021     Document Type: Review

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