Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers

Biomacromolecules

Volumn 10, Issue 5, 2009, Pages 1195-1202

  Chauhan, Abhay S ^a   Diwan, Prakash V ^b   Jain, Narenda K ^c   Tomalia, Donald A ^d  

^a Dendritic NanoTechnologies Inc   (United States)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^c DR H S GOUR UNIVERSITY   (India)

^d CENTRAL MICHIGAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT-INDUCED ARTHRITIS; ANTI-INFLAMMATORY; ANTI-INFLAMMATORY ACTIVITY; ASSAY METHODS; CARRAGEENAN; DIAMINOETHANE; FUNCTIONALIZED; HYDROXYL SURFACE GROUPS; IN-VIVO; INDOMETHACIN; PAMAM DENDRIMER; POLY(AMIDO AMINE); POLYAMIDOAMINE DENDRIMERS; SURFACE FUNCTIONALITIES;

AMINES; BEARINGS (STRUCTURAL); COTTON; DENDRIMERS; DRUG DELIVERY; PELLETIZING;

FUNCTIONAL POLYMERS;

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; AMINE; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DENDRIMER; FREUND ADJUVANT; HYDROXYL GROUP; INDOMETACIN; INDOMETACIN POLYAMIDOAMINE COMPLEX; NITRIC OXIDE; NSC 398; POLYAMIDOAMINE; POLYAMIDOAMINE DENDRIMER; STARBURST; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LEVEL; CONTROLLED STUDY; COTTON PELLET GRANULOMA MODEL; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; ENZYME INHIBITION; EXPERIMENTAL MODEL; MALE; NONHUMAN; PAW EDEMA; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CARRAGEENAN; DENDRIMERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; GRANULOMA; INFLAMMATION; MALE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; POLYAMINES; RATS; RATS, WISTAR; SURFACE PROPERTIES;

GOSSYPIUM HIRSUTUM; RATTUS;

EID: 66149083636     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm9000298     Document Type: Article

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