Dendrimer-based MRI contrast agents: The effects of PEGylation on relaxivity and pharmacokinetics

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 7, Issue 6, 2011, Pages 1001-1008

  Kojima, Chie ^a   Turkbey, Baris ^b   Ogawa, Mikako ^b   Bernardo, Marcelino ^b   Regino, Celeste A S ^b   Bryant, L Henry ^c   Choyke, Peter L ^b   Kono, Kenji ^a   Kobayashi, Hisataka ^b  

^a Osaka Prefecture University   (Japan)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Dendrimer; MRI; Pharmacokinetics; Polyethylene glycol; Relaxivity

Indexed keywords

BLOOD POOL; HIGHER TEMPERATURES; MRI CONTRAST AGENTS; PAMAM DENDRIMER; PEGYLATION; PHARMACOKINETIC PROPERTIES; POLYAMIDOAMINE DENDRIMERS; RELAXIVITY; RETICULOENDOTHELIAL SYSTEMS;

AMINO ACIDS; CHAIN LENGTH; CHELATION; GADOLINIUM; GLYCOLS; MAGNETIC RESONANCE IMAGING; PARAMAGNETIC MATERIALS; PARAMAGNETISM; PHARMACOKINETICS; POLYETHYLENE GLYCOLS; POLYETHYLENES; THERMOPLASTICS;

DENDRIMERS;

DENDRIMER; GADOLINIUM PENTETATE; LYSINE; MACROGOL; POLYAMIDOAMINE;

ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; CIRCULATION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; IN VIVO STUDY; JUGULAR VEIN; KIDNEY; LIVER; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA CLEARANCE; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE;

ANIMALS; CHELATING AGENTS; CONTRAST MEDIA; DENDRIMERS; GADOLINIUM; MAGNETIC RESONANCE IMAGING; MICE; POLYETHYLENE GLYCOLS;

EID: 80955130278     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.03.007     Document Type: Article

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