Mannodendrimers prevent acute lung inflammation by inhibiting neutrophil recruitment

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 22, 2013, Pages 8795-8800

  Blattes, Emilyne ^a,b   Vercellone, Alain ^a,b   Eutamène, Hélène ^c   Turrin, Cédric Olivier ^b,d   Théodorou, Vassilia ^c   Majoral, Jean Pierre ^b,d   Caminade, Anne Marie ^b,d   Prandi, Jacques ^a,b   Nigou, Jérôme ^a,b   Puzo, Germain ^a,b  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

^d CNRS   (France)

Author keywords

Antiinflammatory molecule; Glycodendrimer synthesis; ManLAM functional analogs; Multivalent ligands; SIGNR1 targeting

Indexed keywords

ANTIINFLAMMATORY AGENT; CD209 ANTIGEN; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; DENDRIMER; INTERLEUKIN 10; MANNODENDRIMER; MANNOSE; MANNOSE RECEPTOR; POLY(PHOSPHORHYDRAZONE); TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPARATIVE STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG SYNTHESIS; FEMALE; GLYCOSYLATION; HUMAN; HUMAN CELL; IC 50; LUNG LAVAGE; MOLECULAR WEIGHT; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; RECEPTOR BINDING;

ANTIINFLAMMATORY MOLECULE; GLYCODENDRIMER SYNTHESIS; MANLAM FUNCTIONAL ANALOGS; MULTIVALENT LIGANDS; SIGNR1 TARGETING;

ANIMALS; CELL ADHESION MOLECULES; CYTOKINES; DENDRIMERS; DENDRITIC CELLS; FLOW CYTOMETRY; HUMANS; LECTINS, C-TYPE; LIPOPOLYSACCHARIDES; MAGNETIC RESONANCE SPECTROSCOPY; MANNOSIDES; MICE; MICE, INBRED C57BL; MOLECULAR STRUCTURE; PNEUMONIA; PROTEIN BINDING; RECEPTORS, CELL SURFACE;

MURINAE; MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84878464740     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1221708110     Document Type: Article

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