Interactions of poly(amidoamine) dendrimers with human serum albumin: Binding constants and mechanisms

ACS Nano

Volumn 5, Issue 5, 2011, Pages 3456-3468

  Giri, Jyotsnendu ^a,e   Diallo, Mamadou S ^b,c   Simpson, André J ^d   Liu, Yi ^a   Goddard III, William A ^a   Kumar, Rajeev ^d   Woods, Gwen C ^d  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c California Institute of Technology   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

Dendrimers; Human serum albumin; Nanobiotechnology; Nantoxicology; NMR epitope mapping and atomistic molecular dynamics simulations; Proteins

Indexed keywords

ATOMISTIC MOLECULAR DYNAMICS; BINDING CONSTANT; BIOLOGICAL FLUIDS; DENDRIMER GENERATION; GAIN INSIGHT; HOMOLOGOUS SERIES; HUMAN SERUM ALBUMINS; IN-VIVO; INNER SHELL; MD SIMULATION; NANTOXICOLOGY; NMR DIFFUSION; PAMAM DENDRIMER; PHYSIOLOGICAL PH; PLASMA PROTEIN; POLY(AMIDO AMINE); POLYAMIDOAMINE DENDRIMERS; SATURATION-TRANSFER DIFFERENCES; SIGNIFICANT IMPACTS; SILICA PARTICLES; TERMINAL GROUPS;

BODY FLUIDS; COMPLEXATION; DYNAMICS; EXPERIMENTS; MOLECULAR DYNAMICS; PH EFFECTS; PHYSIOLOGY; PROTEINS; SILICA; SOLUTIONS;

DENDRIMERS;

DENDRIMER; PAMAM STARBURST; SERUM ALBUMIN;

ARTICLE; BINDING SITE; CHEMISTRY; MATERIALS TESTING; PROTEIN BINDING;

BINDING SITES; DENDRIMERS; MATERIALS TESTING; PROTEIN BINDING; SERUM ALBUMIN;

EID: 79960733045     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn1021007     Document Type: Article

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