-
1
-
-
83255188878
-
Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins
-
Slattery M., et al. Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins. Cell 2011, 147:1270-1282.
-
(2011)
Cell
, vol.147
, pp. 1270-1282
-
-
Slattery, M.1
-
2
-
-
84876955991
-
Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape
-
Gordân R., et al. Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. Cell Rep. 2013, 3:1093-1104.
-
(2013)
Cell Rep.
, vol.3
, pp. 1093-1104
-
-
Gordân, R.1
-
3
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S., et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 2010, 38:576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
-
4
-
-
84865257761
-
Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding
-
Yanez-Cuna J.O., et al. Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding. Genome Res. 2012, 22:2018-2030.
-
(2012)
Genome Res.
, vol.22
, pp. 2018-2030
-
-
Yanez-Cuna, J.O.1
-
5
-
-
0034072450
-
DNA binding sites: representation and discovery
-
Stormo G.D. DNA binding sites: representation and discovery. Bioinformatics 2000, 16:16-23.
-
(2000)
Bioinformatics
, vol.16
, pp. 16-23
-
-
Stormo, G.D.1
-
6
-
-
34347237542
-
Predictive modeling of genome-wide mRNA expression: from modules to molecules
-
Bussemaker H.J., et al. Predictive modeling of genome-wide mRNA expression: from modules to molecules. Annu. Rev. Biophys. Biomol. Struct. 2007, 36:329-347.
-
(2007)
Annu. Rev. Biophys. Biomol. Struct.
, vol.36
, pp. 329-347
-
-
Bussemaker, H.J.1
-
7
-
-
67649982744
-
Diversity and complexity in DNA recognition by transcription factors
-
Badis G., et al. Diversity and complexity in DNA recognition by transcription factors. Science 2009, 324:1720-1723.
-
(2009)
Science
, vol.324
, pp. 1720-1723
-
-
Badis, G.1
-
8
-
-
77958096076
-
Determining the specificity of protein-DNA interactions
-
Stormo G.D., Zhao Y. Determining the specificity of protein-DNA interactions. Nat. Rev. Genet. 2010, 11:751-760.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 751-760
-
-
Stormo, G.D.1
Zhao, Y.2
-
9
-
-
84873594686
-
Evaluation of methods for modeling transcription factor sequence specificity
-
Weirauch M.T., et al. Evaluation of methods for modeling transcription factor sequence specificity. Nat. Biotechnol. 2013, 31:126-134.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 126-134
-
-
Weirauch, M.T.1
-
10
-
-
84872540994
-
DNA-binding specificities of human transcription factors
-
Jolma A., et al. DNA-binding specificities of human transcription factors. Cell 2013, 152:327-339.
-
(2013)
Cell
, vol.152
, pp. 327-339
-
-
Jolma, A.1
-
11
-
-
84880362638
-
Massively parallel in vivo enhancer assay reveals that highly local features determine the cis-regulatory function of ChIP-seq peaks
-
White M.A., et al. Massively parallel in vivo enhancer assay reveals that highly local features determine the cis-regulatory function of ChIP-seq peaks. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:11952-11957.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 11952-11957
-
-
White, M.A.1
-
12
-
-
65249167505
-
DNA binding site sequence directs glucocorticoid receptor structure and activity
-
Meijsing S.H., et al. DNA binding site sequence directs glucocorticoid receptor structure and activity. Science 2009, 324:407-410.
-
(2009)
Science
, vol.324
, pp. 407-410
-
-
Meijsing, S.H.1
-
13
-
-
70350686719
-
The role of DNA shape in protein-DNA recognition
-
Rohs R., et al. The role of DNA shape in protein-DNA recognition. Nature 2009, 461:1248-1253.
-
(2009)
Nature
, vol.461
, pp. 1248-1253
-
-
Rohs, R.1
-
14
-
-
84873647198
-
Probing allostery through DNA
-
Kim S., et al. Probing allostery through DNA. Science 2013, 339:816-819.
-
(2013)
Science
, vol.339
, pp. 816-819
-
-
Kim, S.1
-
15
-
-
84880174882
-
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals
-
Watson L.C., et al. The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals. Nat. Struct. Mol. Biol. 2013, 20:876-883.
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 876-883
-
-
Watson, L.C.1
-
16
-
-
83455164709
-
Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex
-
Siggers T., et al. Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex. Mol. Syst. Biol. 2011, 7:555.
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 555
-
-
Siggers, T.1
-
18
-
-
70350741354
-
An ensemble model of competitive multi-factor binding of the genome
-
Wasson T., Hartemink A.J. An ensemble model of competitive multi-factor binding of the genome. Genome Res. 2009, 19:2101-2112.
-
(2009)
Genome Res.
, vol.19
, pp. 2101-2112
-
-
Wasson, T.1
Hartemink, A.J.2
-
19
-
-
77950484709
-
Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs
-
Kitayner M., et al. Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs. Nat. Struct. Mol. Biol. 2010, 17:423-429.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 423-429
-
-
Kitayner, M.1
-
20
-
-
33749381311
-
Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection
-
Liu X., et al. Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection. Genome Res. 2006, 16:1517-1528.
-
(2006)
Genome Res.
, vol.16
, pp. 1517-1528
-
-
Liu, X.1
-
21
-
-
62649085538
-
The DNA-encoded nucleosome organization of a eukaryotic genome
-
Kaplan N., et al. The DNA-encoded nucleosome organization of a eukaryotic genome. Nature 2009, 458:362-366.
-
(2009)
Nature
, vol.458
, pp. 362-366
-
-
Kaplan, N.1
-
22
-
-
77957883572
-
Gene regulation by nucleosome positioning
-
Bai L., Morozov A.V. Gene regulation by nucleosome positioning. Trends Genet. 2010, 26:476-483.
-
(2010)
Trends Genet.
, vol.26
, pp. 476-483
-
-
Bai, L.1
Morozov, A.V.2
-
23
-
-
79952273012
-
Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development
-
Kaplan T., et al. Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development. PLoS Genet. 2011, 7:e1001290.
-
(2011)
PLoS Genet.
, vol.7
-
-
Kaplan, T.1
-
24
-
-
79952266465
-
Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
-
Pique-Regi R., et al. Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res. 2011, 21:447-455.
-
(2011)
Genome Res.
, vol.21
, pp. 447-455
-
-
Pique-Regi, R.1
-
25
-
-
84865852567
-
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
-
Wang J., et al. Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Res. 2012, 22:1798-1812.
-
(2012)
Genome Res.
, vol.22
, pp. 1798-1812
-
-
Wang, J.1
-
26
-
-
0037369952
-
Collaborative competition mechanism for gene activation in vivo
-
Miller J.A., Widom J. Collaborative competition mechanism for gene activation in vivo. Mol. Cell. Biol. 2003, 23:1623-1632.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 1623-1632
-
-
Miller, J.A.1
Widom, J.2
-
27
-
-
78651107675
-
Nucleosome-mediated cooperativity between transcription factors
-
Mirny L.A. Nucleosome-mediated cooperativity between transcription factors. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:22534-22539.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 22534-22539
-
-
Mirny, L.A.1
-
28
-
-
79958071005
-
Recognizing and remodeling the nucleosome
-
Glatt S., et al. Recognizing and remodeling the nucleosome. Curr. Opin. Struct. Biol. 2011, 21:335-341.
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 335-341
-
-
Glatt, S.1
-
29
-
-
84901921616
-
Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
-
Barozzi I., et al. Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers. Mol. Cell 2014, 54:844-857.
-
(2014)
Mol. Cell
, vol.54
, pp. 844-857
-
-
Barozzi, I.1
-
30
-
-
84876245094
-
Probing DNA shape and methylation state on a genomic scale with DNase I
-
Lazarovici A., et al. Probing DNA shape and methylation state on a genomic scale with DNase I. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:6376-6381.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 6376-6381
-
-
Lazarovici, A.1
-
31
-
-
78049440479
-
High resolution models of transcription factor-DNA affinities improve in vitro and in vivo binding predictions
-
Agius P., et al. High resolution models of transcription factor-DNA affinities improve in vitro and in vivo binding predictions. PLoS Comput. Biol. 2010, 6:e1000916.
-
(2010)
PLoS Comput. Biol.
, vol.6
-
-
Agius, P.1
-
32
-
-
0035930331
-
Recognition of specific DNA sequences
-
Garvie C.W., Wolberger C. Recognition of specific DNA sequences. Mol. Cell 2001, 8:937-946.
-
(2001)
Mol. Cell
, vol.8
, pp. 937-946
-
-
Garvie, C.W.1
Wolberger, C.2
-
33
-
-
34347235771
-
From 'simple' DNA-protein interactions to the macromolecular machines of gene expression
-
von Hippel P.H. From 'simple' DNA-protein interactions to the macromolecular machines of gene expression. Annu. Rev. Biophys. Biomol. Struct. 2007, 36:79-105.
-
(2007)
Annu. Rev. Biophys. Biomol. Struct.
, vol.36
, pp. 79-105
-
-
von Hippel, P.H.1
-
34
-
-
77957968202
-
Structural basis for sequence-specific DNA recognition by transcription factors and their complexes
-
Royal Society of Chemistry, P.A. Rice, C.C. Correll (Eds.)
-
Hong M., Marmorstein R. Structural basis for sequence-specific DNA recognition by transcription factors and their complexes. Protein-Nucleic Acid Interactions: Structural Biology 2008, 47-65. Royal Society of Chemistry. P.A. Rice, C.C. Correll (Eds.).
-
(2008)
Protein-Nucleic Acid Interactions: Structural Biology
, pp. 47-65
-
-
Hong, M.1
Marmorstein, R.2
-
35
-
-
60149104870
-
Indirect readout of DNA sequence by proteins
-
Royal Society of Chemistry, P.A. Rice, C.C. Correll (Eds.)
-
Lawson C.L., Berman H.M. Indirect readout of DNA sequence by proteins. Protein-Nucleic Acid Interactions: Structural Biology 2008, 66-90. Royal Society of Chemistry. P.A. Rice, C.C. Correll (Eds.).
-
(2008)
Protein-Nucleic Acid Interactions: Structural Biology
, pp. 66-90
-
-
Lawson, C.L.1
Berman, H.M.2
-
36
-
-
49449107340
-
Visualizing one-dimensional diffusion of proteins along DNA
-
Gorman J., Greene E.C. Visualizing one-dimensional diffusion of proteins along DNA. Nat. Struct. Mol. Biol. 2008, 15:768-774.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 768-774
-
-
Gorman, J.1
Greene, E.C.2
-
37
-
-
67749095703
-
Hox specificity unique roles for cofactors and collaborators
-
Mann R.S., et al. Hox specificity unique roles for cofactors and collaborators. Curr. Top. Dev. Biol. 2009, 88:63-101.
-
(2009)
Curr. Top. Dev. Biol.
, vol.88
, pp. 63-101
-
-
Mann, R.S.1
-
38
-
-
75149141847
-
Mechanisms of transcription factor selectivity
-
Pan Y., et al. Mechanisms of transcription factor selectivity. Trends Genet. 2010, 26:75-83.
-
(2010)
Trends Genet.
, vol.26
, pp. 75-83
-
-
Pan, Y.1
-
39
-
-
77950519937
-
Origins of specificity in protein-DNA recognition
-
Rohs R., et al. Origins of specificity in protein-DNA recognition. Annu. Rev. Biochem. 2010, 79:233-269.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 233-269
-
-
Rohs, R.1
-
40
-
-
79958051799
-
DNA shape, genetic codes, and evolution
-
Parker S.C., Tullius T.D. DNA shape, genetic codes, and evolution. Curr. Opin. Struct. Biol. 2011, 21:342-347.
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 342-347
-
-
Parker, S.C.1
Tullius, T.D.2
-
41
-
-
84870222914
-
Disentangling the many layers of eukaryotic transcriptional regulation
-
Lelli K.M., et al. Disentangling the many layers of eukaryotic transcriptional regulation. Annu. Rev. Genet. 2012, 46:43-68.
-
(2012)
Annu. Rev. Genet.
, vol.46
, pp. 43-68
-
-
Lelli, K.M.1
-
42
-
-
84861775142
-
Towards a molecular view of transcriptional control
-
Zakrzewska K., Lavery R. Towards a molecular view of transcriptional control. Curr. Opin. Struct. Biol. 2012, 22:160-167.
-
(2012)
Curr. Opin. Struct. Biol.
, vol.22
, pp. 160-167
-
-
Zakrzewska, K.1
Lavery, R.2
-
43
-
-
84885841612
-
Modeling the specificity of protein-DNA interactions
-
Stormo G.D. Modeling the specificity of protein-DNA interactions. Quant. Biol. 2013, 1:115-130.
-
(2013)
Quant. Biol.
, vol.1
, pp. 115-130
-
-
Stormo, G.D.1
-
44
-
-
84887628076
-
Lineages, cell types and functional states: a genomic view
-
Ostuni R., Natoli G. Lineages, cell types and functional states: a genomic view. Curr. Opin. Cell Biol. 2013, 25:759-764.
-
(2013)
Curr. Opin. Cell Biol.
, vol.25
, pp. 759-764
-
-
Ostuni, R.1
Natoli, G.2
-
45
-
-
84901192605
-
The grammar of transcriptional regulation
-
Weingarten-Gabbay S., Segal E. The grammar of transcriptional regulation. Hum. Genet. 2014, 133:701-711.
-
(2014)
Hum. Genet.
, vol.133
, pp. 701-711
-
-
Weingarten-Gabbay, S.1
Segal, E.2
-
46
-
-
84899450857
-
Transcriptional enhancers: from properties to genome-wide predictions
-
Shlyueva D., et al. Transcriptional enhancers: from properties to genome-wide predictions. Nat. Rev. Genet. 2014, 15:272-286.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 272-286
-
-
Shlyueva, D.1
-
47
-
-
84895810018
-
Protein-DNA binding: complexities and multi-protein codes
-
Siggers T., Gordân R. Protein-DNA binding: complexities and multi-protein codes. Nucleic Acids Res. 2014, 42:2099-2111.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 2099-2111
-
-
Siggers, T.1
Gordân, R.2
-
48
-
-
84902810053
-
In pursuit of design principles of regulatory sequences
-
Levo M., Segal E. In pursuit of design principles of regulatory sequences. Nat. Rev. Genet. 2014, 15:453-468.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 453-468
-
-
Levo, M.1
Segal, E.2
-
49
-
-
64649095501
-
Nuance in the double-helix and its role in protein-DNA recognition
-
Rohs R., et al. Nuance in the double-helix and its role in protein-DNA recognition. Curr. Opin. Struct. Biol. 2009, 19:171-177.
-
(2009)
Curr. Opin. Struct. Biol.
, vol.19
, pp. 171-177
-
-
Rohs, R.1
-
50
-
-
0033954256
-
The Protein Data Bank
-
Berman H.M., et al. The Protein Data Bank. Nucleic Acids Res. 2000, 28:235-242.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
-
51
-
-
77950934795
-
The shape of the DNA minor groove directs binding by the DNA-bending protein Fis
-
Stella S., et al. The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes Dev. 2010, 24:814-826.
-
(2010)
Genes Dev.
, vol.24
, pp. 814-826
-
-
Stella, S.1
-
52
-
-
84880528662
-
Control of DNA minor groove width and Fis protein binding by the purine 2-amino group
-
Hancock S.P., et al. Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic Acids Res. 2013, 41:6750-6760.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 6750-6760
-
-
Hancock, S.P.1
-
53
-
-
84884964169
-
Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion
-
Chen Y., et al. Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion. Nucleic Acids Res. 2013, 41:8368-8376.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 8368-8376
-
-
Chen, Y.1
-
54
-
-
84876982103
-
Mechanism of origin DNA recognition and assembly of an initiator-helicase complex by SV40 large tumor antigen
-
Chang Y.P., et al. Mechanism of origin DNA recognition and assembly of an initiator-helicase complex by SV40 large tumor antigen. Cell Rep. 2013, 3:1117-1127.
-
(2013)
Cell Rep.
, vol.3
, pp. 1117-1127
-
-
Chang, Y.P.1
-
55
-
-
84869765376
-
Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes
-
Dantas Machado A.C., et al. Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes. Biochem. Mol. Biol. Educ. 2012, 40:400-401.
-
(2012)
Biochem. Mol. Biol. Educ.
, vol.40
, pp. 400-401
-
-
Dantas Machado, A.C.1
-
56
-
-
84870397179
-
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation
-
Chen Y., et al. DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation. Cell Rep. 2012, 2:1197-1206.
-
(2012)
Cell Rep.
, vol.2
, pp. 1197-1206
-
-
Chen, Y.1
-
57
-
-
84895833555
-
Conformations of p53 response elements in solution deduced using site-directed spin labeling and Monte Carlo sampling
-
Zhang X., et al. Conformations of p53 response elements in solution deduced using site-directed spin labeling and Monte Carlo sampling. Nucleic Acids Res. 2014, 42:2789-2797.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 2789-2797
-
-
Zhang, X.1
-
58
-
-
26444478194
-
Structural and energetic origins of sequence-specific DNA bending: Monte Carlo simulations of papillomavirus E2-DNA binding sites
-
Rohs R., et al. Structural and energetic origins of sequence-specific DNA bending: Monte Carlo simulations of papillomavirus E2-DNA binding sites. Structure 2005, 13:1499-1509.
-
(2005)
Structure
, vol.13
, pp. 1499-1509
-
-
Rohs, R.1
-
59
-
-
34250017968
-
An atomic model of the interferon-beta enhanceosome
-
Panne D., et al. An atomic model of the interferon-beta enhanceosome. Cell 2007, 129:1111-1123.
-
(2007)
Cell
, vol.129
, pp. 1111-1123
-
-
Panne, D.1
-
60
-
-
0028685490
-
Fitting a mixture model by expectation maximization to discover motifs in biopolymers
-
Bailey T.L., Elkan C. Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc. Internat. Conf. Intell. Syst. Mol. Biol. 1994, 2:28-36.
-
(1994)
Proc. Internat. Conf. Intell. Syst. Mol. Biol.
, vol.2
, pp. 28-36
-
-
Bailey, T.L.1
Elkan, C.2
-
61
-
-
0031787969
-
Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation
-
Roth F.P., et al. Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation. Nat. Biotechnol. 1998, 16:939-945.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 939-945
-
-
Roth, F.P.1
-
62
-
-
0034565285
-
Combinatorial approaches to finding subtle signals in DNA sequences
-
Pevzner P.A., Sze S.H. Combinatorial approaches to finding subtle signals in DNA sequences. Proc. Int. Conf. Intell. Syst. Mol. Biol. 2000, 8:269-278.
-
(2000)
Proc. Int. Conf. Intell. Syst. Mol. Biol.
, vol.8
, pp. 269-278
-
-
Pevzner, P.A.1
Sze, S.H.2
-
64
-
-
0018199224
-
DNAse footprinting: a simple method for the detection of protein-DNA binding specificity
-
Galas D.J., Schmitz A. DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res. 1978, 5:3157-3170.
-
(1978)
Nucleic Acids Res.
, vol.5
, pp. 3157-3170
-
-
Galas, D.J.1
Schmitz, A.2
-
65
-
-
0019877067
-
A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system
-
Garner M.M., Revzin A. A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res. 1981, 9:3047-3060.
-
(1981)
Nucleic Acids Res.
, vol.9
, pp. 3047-3060
-
-
Garner, M.M.1
Revzin, A.2
-
66
-
-
21144439147
-
Assessing computational tools for the discovery of transcription factor binding sites
-
Tompa M., et al. Assessing computational tools for the discovery of transcription factor binding sites. Nat. Biotechnol. 2005, 23:137-144.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 137-144
-
-
Tompa, M.1
-
67
-
-
34247579156
-
A survey of motif discovery methods in an integrated framework
-
Sandve G.K., Drablos F. A survey of motif discovery methods in an integrated framework. Biol. Direct 2006, 1:11.
-
(2006)
Biol. Direct
, vol.1
, pp. 11
-
-
Sandve, G.K.1
Drablos, F.2
-
68
-
-
22344457014
-
EnoLOGOS: a versatile web tool for energy normalized sequence logos
-
Workman C.T., et al. enoLOGOS: a versatile web tool for energy normalized sequence logos. Nucleic Acids Res. 2005, 33:W389-W392.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Workman, C.T.1
-
69
-
-
0035875327
-
Non-independence of Mnt repressor-operator interaction determined by a new quantitative multiple fluorescence relative affinity (QuMFRA) assay
-
Man T.K., Stormo G.D. Non-independence of Mnt repressor-operator interaction determined by a new quantitative multiple fluorescence relative affinity (QuMFRA) assay. Nucleic Acids Res. 2001, 29:2471-2478.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2471-2478
-
-
Man, T.K.1
Stormo, G.D.2
-
70
-
-
0036493201
-
Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors
-
Bulyk M.L., et al. Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors. Nucleic Acids Res. 2002, 30:1255-1261.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 1255-1261
-
-
Bulyk, M.L.1
-
71
-
-
34249654609
-
Position dependencies in transcription factor binding sites
-
Tomovic A., Oakeley E.J. Position dependencies in transcription factor binding sites. Bioinformatics 2007, 23:933-941.
-
(2007)
Bioinformatics
, vol.23
, pp. 933-941
-
-
Tomovic, A.1
Oakeley, E.J.2
-
72
-
-
50949097456
-
A feature-based approach to modeling protein-DNA interactions
-
Sharon E., et al. A feature-based approach to modeling protein-DNA interactions. PLoS Comput. Biol. 2008, 4:e1000154.
-
(2008)
PLoS Comput. Biol.
, vol.4
-
-
Sharon, E.1
-
73
-
-
84863866025
-
Improved models for transcription factor binding site identification using nonindependent interactions
-
Zhao Y., et al. Improved models for transcription factor binding site identification using nonindependent interactions. Genetics 2012, 191:781-790.
-
(2012)
Genetics
, vol.191
, pp. 781-790
-
-
Zhao, Y.1
-
74
-
-
84879970323
-
Stability selection for regression-based models of transcription factor-DNA binding specificity
-
Mordelet F., et al. Stability selection for regression-based models of transcription factor-DNA binding specificity. Bioinformatics 2013, 29:i117-i125.
-
(2013)
Bioinformatics
, vol.29
-
-
Mordelet, F.1
-
75
-
-
47249118465
-
Extracting sequence features to predict protein-DNA interactions: a comparative study
-
Zhou Q., Liu J.S. Extracting sequence features to predict protein-DNA interactions: a comparative study. Nucleic Acids Res. 2008, 36:4137-4148.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 4137-4148
-
-
Zhou, Q.1
Liu, J.S.2
-
76
-
-
0032530555
-
DNA sequence-dependent deformability deduced from protein-DNA crystal complexes
-
Olson W.K., et al. DNA sequence-dependent deformability deduced from protein-DNA crystal complexes. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:11163-11168.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 11163-11168
-
-
Olson, W.K.1
-
77
-
-
0000388872
-
DNA bending by adenine-thymine tracts
-
Oxford University Press, S. Neidle (Ed.)
-
Crothers D.M., Shakked Z. DNA bending by adenine-thymine tracts. Oxford Handbook of Nucleic Acid Structures 1999, 455-470. Oxford University Press. S. Neidle (Ed.).
-
(1999)
Oxford Handbook of Nucleic Acid Structures
, pp. 455-470
-
-
Crothers, D.M.1
Shakked, Z.2
-
78
-
-
84883590358
-
DNAshape: a method for the high-throughput prediction of DNA structural features on a genomic scale
-
Zhou T., et al. DNAshape: a method for the high-throughput prediction of DNA structural features on a genomic scale. Nucleic Acids Res. 2013, 41:W56-W62.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Zhou, T.1
-
79
-
-
84891768983
-
TFBSshape: a motif database for DNA shape features of transcription factor binding sites
-
Yang L., et al. TFBSshape: a motif database for DNA shape features of transcription factor binding sites. Nucleic Acids Res. 2014, 42:D148-D155.
-
(2014)
Nucleic Acids Res.
, vol.42
-
-
Yang, L.1
-
80
-
-
84891777143
-
Covariation between homeodomain transcription factors and the shape of their DNA binding sites
-
Dror I., et al. Covariation between homeodomain transcription factors and the shape of their DNA binding sites. Nucleic Acids Res. 2014, 42:430-441.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 430-441
-
-
Dror, I.1
-
81
-
-
33846700587
-
Predicting transcription factor affinities to DNA from a biophysical model
-
Roider H.G., et al. Predicting transcription factor affinities to DNA from a biophysical model. Bioinformatics 2007, 23:134-141.
-
(2007)
Bioinformatics
, vol.23
, pp. 134-141
-
-
Roider, H.G.1
-
82
-
-
74549209548
-
Inferring binding energies from selected binding sites
-
Zhao Y., et al. Inferring binding energies from selected binding sites. PLoS Comput. Biol. 2009, 5:e1000590.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Zhao, Y.1
-
83
-
-
84878882810
-
TherMos: estimating protein-DNA binding energies from in vivo binding profiles
-
Sun W., et al. TherMos: estimating protein-DNA binding energies from in vivo binding profiles. Nucleic Acids Res. 2013, 41:5555-5568.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 5555-5568
-
-
Sun, W.1
-
84
-
-
0032524713
-
Quantitative parameters for amino acid-base interaction: implications for prediction of protein-DNA binding sites
-
Mandel-Gutfreund Y., Margalit H. Quantitative parameters for amino acid-base interaction: implications for prediction of protein-DNA binding sites. Nucleic Acids Res. 1998, 26:2306-2312.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2306-2312
-
-
Mandel-Gutfreund, Y.1
Margalit, H.2
-
85
-
-
7044239239
-
A simple physical model for the prediction and design of protein-DNA interactions
-
Havranek J.J., et al. A simple physical model for the prediction and design of protein-DNA interactions. J. Mol. Biol. 2004, 344:59-70.
-
(2004)
J. Mol. Biol.
, vol.344
, pp. 59-70
-
-
Havranek, J.J.1
-
86
-
-
27244460904
-
Protein-DNA binding specificity predictions with structural models
-
Morozov A.V., et al. Protein-DNA binding specificity predictions with structural models. Nucleic Acids Res. 2005, 33:5781-5798.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5781-5798
-
-
Morozov, A.V.1
-
87
-
-
29444434700
-
Ab initio prediction of transcription factor targets using structural knowledge
-
Kaplan T., et al. Ab initio prediction of transcription factor targets using structural knowledge. PLoS Comput. Biol. 2005, 1:e1.
-
(2005)
PLoS Comput. Biol.
, vol.1
-
-
Kaplan, T.1
-
88
-
-
11844279783
-
Structural alignment of protein-DNA interfaces: insights into the determinants of binding specificity
-
Siggers T.W., et al. Structural alignment of protein-DNA interfaces: insights into the determinants of binding specificity. J. Mol. Biol. 2005, 345:1027-1045.
-
(2005)
J. Mol. Biol.
, vol.345
, pp. 1027-1045
-
-
Siggers, T.W.1
-
89
-
-
34047153962
-
Structure-based prediction of C2H2 zinc-finger binding specificity: sensitivity to docking geometry
-
Siggers T.W., Honig B. Structure-based prediction of C2H2 zinc-finger binding specificity: sensitivity to docking geometry. Nucleic Acids Res. 2007, 35:1085-1097.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 1085-1097
-
-
Siggers, T.W.1
Honig, B.2
-
90
-
-
84865283412
-
Atomistic modeling of protein-DNA interaction specificity: progress and applications
-
Liu L.A., Bradley P. Atomistic modeling of protein-DNA interaction specificity: progress and applications. Curr. Opin. Struct. Biol. 2012, 22:397-405.
-
(2012)
Curr. Opin. Struct. Biol.
, vol.22
, pp. 397-405
-
-
Liu, L.A.1
Bradley, P.2
-
91
-
-
84871226594
-
Improved predictions of transcription factor binding sites using physicochemical features of DNA
-
Maienschein-Cline M., et al. Improved predictions of transcription factor binding sites using physicochemical features of DNA. Nucleic Acids Res. 2012, 40:e175.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Maienschein-Cline, M.1
-
92
-
-
84864960989
-
A flexible integrative approach based on random forest improves prediction of transcription factor binding sites
-
Hooghe B., et al. A flexible integrative approach based on random forest improves prediction of transcription factor binding sites. Nucleic Acids Res. 2012, 40:e106.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Hooghe, B.1
-
93
-
-
84886864198
-
Evaluating a linear k-mer model for protein-DNA interactions using high-throughput SELEX data
-
Kahara J., Lahdesmaki H. Evaluating a linear k-mer model for protein-DNA interactions using high-throughput SELEX data. BMC bioinformatics 2013, 14(Suppl 10):S2.
-
(2013)
BMC bioinformatics
, vol.14
, Issue.SUPPL. 10
-
-
Kahara, J.1
Lahdesmaki, H.2
-
94
-
-
33750882505
-
Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities
-
Berger M.F., et al. Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities. Nat. Biotechnol. 2006, 24:1429-1435.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1429-1435
-
-
Berger, M.F.1
-
95
-
-
79960860669
-
Extensive characterization of NF-kappaB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits
-
Wong D., et al. Extensive characterization of NF-kappaB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits. Genome Biol. 2011, 12:R70.
-
(2011)
Genome Biol.
, vol.12
-
-
Wong, D.1
-
96
-
-
83855162723
-
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-kappaB family DNA binding
-
Siggers T., et al. Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-kappaB family DNA binding. Nat. Immunol. 2012, 13:95-102.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 95-102
-
-
Siggers, T.1
-
97
-
-
33746691336
-
Extensive low-affinity transcriptional interactions in the yeast genome
-
Tanay A. Extensive low-affinity transcriptional interactions in the yeast genome. Genome Res. 2006, 16:962-972.
-
(2006)
Genome Res.
, vol.16
, pp. 962-972
-
-
Tanay, A.1
-
98
-
-
77950339177
-
Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites
-
Jaeger S.A., et al. Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics 2010, 95:185-195.
-
(2010)
Genomics
, vol.95
, pp. 185-195
-
-
Jaeger, S.A.1
-
99
-
-
77952352833
-
Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity
-
Rowan S., et al. Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev. 2010, 24:980-985.
-
(2010)
Genes Dev.
, vol.24
, pp. 980-985
-
-
Rowan, S.1
-
100
-
-
84866983699
-
A model of spatially restricted transcription in opposing gradients of activators and repressors
-
White M.A., et al. A model of spatially restricted transcription in opposing gradients of activators and repressors. Mol. Syst. Biol. 2012, 8:614.
-
(2012)
Mol. Syst. Biol.
, vol.8
, pp. 614
-
-
White, M.A.1
-
101
-
-
33846467150
-
A systems approach to measuring the binding energy landscapes of transcription factors
-
Maerkl S.J., Quake S.R. A systems approach to measuring the binding energy landscapes of transcription factors. Science 2007, 315:233-237.
-
(2007)
Science
, vol.315
, pp. 233-237
-
-
Maerkl, S.J.1
Quake, S.R.2
-
102
-
-
45449111373
-
Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites
-
Noyes M.B., et al. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 2008, 133:1277-1289.
-
(2008)
Cell
, vol.133
, pp. 1277-1289
-
-
Noyes, M.B.1
-
103
-
-
67949120337
-
Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays
-
Bonham A.J., et al. Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays. Nucleic Acids Res. 2009, 37:e94.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Bonham, A.J.1
-
104
-
-
83755196322
-
Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights
-
Gordân R., et al. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol. 2011, 12:R125.
-
(2011)
Genome Biol.
, vol.12
-
-
Gordân, R.1
-
105
-
-
84880681583
-
DNA-binding specificity changes in the evolution of forkhead transcription factors
-
Nakagawa S., et al. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:12349-12354.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 12349-12354
-
-
Nakagawa, S.1
-
106
-
-
45449115390
-
Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences
-
Berger M.F., et al. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 2008, 133:1266-1276.
-
(2008)
Cell
, vol.133
, pp. 1266-1276
-
-
Berger, M.F.1
-
107
-
-
84867157760
-
Exploring the DNA-recognition potential of homeodomains
-
Chu S.W., et al. Exploring the DNA-recognition potential of homeodomains. Genome Res. 2012, 22:1889-1898.
-
(2012)
Genome Res.
, vol.22
, pp. 1889-1898
-
-
Chu, S.W.1
-
108
-
-
79960277492
-
Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument
-
Nutiu R., et al. Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument. Nat. Biotechnol. 2011, 29:659-664.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 659-664
-
-
Nutiu, R.1
-
109
-
-
0029036735
-
Determinants of half-site spacing preferences that distinguish AP-1 and ATF/CREB bZIP domains
-
Kim J., Struhl K. Determinants of half-site spacing preferences that distinguish AP-1 and ATF/CREB bZIP domains. Nucleic Acids Res. 1995, 23:2531-2537.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 2531-2537
-
-
Kim, J.1
Struhl, K.2
-
110
-
-
77953006022
-
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities
-
Jolma A., et al. Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. Genome Res. 2010, 20:861-873.
-
(2010)
Genome Res.
, vol.20
, pp. 861-873
-
-
Jolma, A.1
-
111
-
-
84868588824
-
Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses
-
Fordyce P.M., et al. Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:E3084-E3093.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
-
-
Fordyce, P.M.1
-
113
-
-
84879101308
-
Changes to cellular water and element content induced by nucleolar stress: investigation by a cryo-correlative nano-imaging approach
-
Nolin F., et al. Changes to cellular water and element content induced by nucleolar stress: investigation by a cryo-correlative nano-imaging approach. Cell. Mol. Life Sci. 2013, 70:2383-2394.
-
(2013)
Cell. Mol. Life Sci.
, vol.70
, pp. 2383-2394
-
-
Nolin, F.1
-
114
-
-
79953054018
-
Miniseries: Illustrating the machinery of life: eukaryotic cell panorama
-
Goodsell D.S. Miniseries: Illustrating the machinery of life: eukaryotic cell panorama. Biochem. Mol. Biol. Educ. 2011, 39:91-101.
-
(2011)
Biochem. Mol. Biol. Educ.
, vol.39
, pp. 91-101
-
-
Goodsell, D.S.1
-
115
-
-
84890072854
-
Exonic transcription factor binding directs codon choice and affects protein evolution
-
Stergachis A.B., et al. Exonic transcription factor binding directs codon choice and affects protein evolution. Science 2013, 342:1367-1372.
-
(2013)
Science
, vol.342
, pp. 1367-1372
-
-
Stergachis, A.B.1
-
116
-
-
77954762633
-
Annotating non-coding regions of the genome
-
Alexander R.P., et al. Annotating non-coding regions of the genome. Nat. Rev. Genet. 2010, 11:559-571.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 559-571
-
-
Alexander, R.P.1
-
117
-
-
77957903560
-
The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation
-
Lin Z., et al. The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation. BMC Genomics 2010, 11:581.
-
(2010)
BMC Genomics
, vol.11
, pp. 581
-
-
Lin, Z.1
-
118
-
-
84870794209
-
A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes
-
El-Kasti M.M., et al. A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes. Hum. Mol. Genet. 2012, 21:5429-5442.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 5429-5442
-
-
El-Kasti, M.M.1
-
119
-
-
79955364415
-
An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene
-
Hosoya-Ohmura S., et al. An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene. Mol. Cell. Biol. 2011, 31:1894-1904.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1894-1904
-
-
Hosoya-Ohmura, S.1
-
120
-
-
84886909517
-
A far downstream enhancer for murine Bcl11b controls its T-cell specific expression
-
Li L., et al. A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. Blood 2013, 122:902-911.
-
(2013)
Blood
, vol.122
, pp. 902-911
-
-
Li, L.1
-
121
-
-
84901804887
-
Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features
-
Yanez-Cuna J.O., et al. Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features. Genome Res. 2014, 24:1147-1156.
-
(2014)
Genome Res.
, vol.24
, pp. 1147-1156
-
-
Yanez-Cuna, J.O.1
-
122
-
-
84867120185
-
Interpreting the regulatory genome: the genomics of transcription factor function in Drosophila melanogaster
-
Slattery M., et al. Interpreting the regulatory genome: the genomics of transcription factor function in Drosophila melanogaster. Brief. Funct. Genomics 2012, 11:336-346.
-
(2012)
Brief. Funct. Genomics
, vol.11
, pp. 336-346
-
-
Slattery, M.1
-
123
-
-
84874381107
-
Genome-wide quantitative enhancer activity maps identified by STARR-seq
-
Arnold C.D., et al. Genome-wide quantitative enhancer activity maps identified by STARR-seq. Science 2013, 339:1074-1077.
-
(2013)
Science
, vol.339
, pp. 1074-1077
-
-
Arnold, C.D.1
-
124
-
-
84881442078
-
Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos
-
Gisselbrecht S.S., et al. Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos. Nat. Methods 2013, 10:774-780.
-
(2013)
Nat. Methods
, vol.10
, pp. 774-780
-
-
Gisselbrecht, S.S.1
-
125
-
-
84868088171
-
A survey of 6,300 genomic fragments for cis-regulatory activity in the imaginal discs of Drosophila melanogaster
-
Jory A., et al. A survey of 6,300 genomic fragments for cis-regulatory activity in the imaginal discs of Drosophila melanogaster. Cell Rep. 2012, 2:1014-1024.
-
(2012)
Cell Rep.
, vol.2
, pp. 1014-1024
-
-
Jory, A.1
-
126
-
-
84868097251
-
A resource for manipulating gene expression and analyzing cis-regulatory modules in the Drosophila CNS
-
Manning L., et al. A resource for manipulating gene expression and analyzing cis-regulatory modules in the Drosophila CNS. Cell Rep. 2012, 2:1002-1013.
-
(2012)
Cell Rep.
, vol.2
, pp. 1002-1013
-
-
Manning, L.1
-
127
-
-
84868114222
-
A GAL4-driver line resource for Drosophila neurobiology
-
Jenett A., et al. A GAL4-driver line resource for Drosophila neurobiology. Cell Rep. 2012, 2:991-1001.
-
(2012)
Cell Rep.
, vol.2
, pp. 991-1001
-
-
Jenett, A.1
-
128
-
-
84863230316
-
Massively parallel functional dissection of mammalian enhancers in vivo
-
Patwardhan R.P., et al. Massively parallel functional dissection of mammalian enhancers in vivo. Nat. Biotechnol. 2012, 30:265-270.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 265-270
-
-
Patwardhan, R.P.1
-
129
-
-
84898025687
-
Hormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin
-
Shlyueva D., et al. Hormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin. Mol. Cell 2014, 54:180-192.
-
(2014)
Mol. Cell
, vol.54
, pp. 180-192
-
-
Shlyueva, D.1
-
130
-
-
84905642951
-
Genome-scale functional characterization of Drosophila developmental enhancers in vivo
-
Kvon E.Z., et al. Genome-scale functional characterization of Drosophila developmental enhancers in vivo. Nature 2014, 512:91-95.
-
(2014)
Nature
, vol.512
, pp. 91-95
-
-
Kvon, E.Z.1
-
131
-
-
79953044960
-
Genome-wide transcription factor binding: beyond direct target regulation
-
MacQuarrie K.L., et al. Genome-wide transcription factor binding: beyond direct target regulation. Trends Genet. 2011, 27:141-148.
-
(2011)
Trends Genet.
, vol.27
, pp. 141-148
-
-
MacQuarrie, K.L.1
-
132
-
-
68949213578
-
Insights from genomic profiling of transcription factors
-
Farnham P.J. Insights from genomic profiling of transcription factors. Nat. Rev. Genet. 2009, 10:605-616.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 605-616
-
-
Farnham, P.J.1
-
133
-
-
80054728495
-
Animal transcription networks as highly connected, quantitative continua
-
Biggin M.D. Animal transcription networks as highly connected, quantitative continua. Dev. Cell 2011, 21:611-626.
-
(2011)
Dev. Cell
, vol.21
, pp. 611-626
-
-
Biggin, M.D.1
-
134
-
-
40149095913
-
Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm
-
Li X.Y., et al. Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm. PLoS Biol. 2008, 6:e27.
-
(2008)
PLoS Biol.
, vol.6
-
-
Li, X.Y.1
-
135
-
-
84871844925
-
DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila
-
Fisher W.W., et al. DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:21330-21335.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 21330-21335
-
-
Fisher, W.W.1
-
136
-
-
70349961774
-
Different gene regulation strategies revealed by analysis of binding motifs
-
Wunderlich Z., Mirny L.A. Different gene regulation strategies revealed by analysis of binding motifs. Trends Genet. 2009, 25:434-440.
-
(2009)
Trends Genet.
, vol.25
, pp. 434-440
-
-
Wunderlich, Z.1
Mirny, L.A.2
-
137
-
-
84884829249
-
Mapping human epigenomes
-
Rivera C.M., Ren B. Mapping human epigenomes. Cell 2013, 155:39-55.
-
(2013)
Cell
, vol.155
, pp. 39-55
-
-
Rivera, C.M.1
Ren, B.2
-
138
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M., et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 2011, 146:1016-1028.
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
-
139
-
-
84904541089
-
Interpreting the language of histone and DNA modifications
-
Rothbart S.B., Strahl B.D. Interpreting the language of histone and DNA modifications. Biochim. Biophys. Acta 2014, 1839:627-643.
-
(2014)
Biochim. Biophys. Acta
, vol.1839
, pp. 627-643
-
-
Rothbart, S.B.1
Strahl, B.D.2
-
140
-
-
84860371870
-
Combinatorial complexity in chromatin structure and function: revisiting the histone code
-
Rando O.J. Combinatorial complexity in chromatin structure and function: revisiting the histone code. Curr. Opin. Genet. Dev. 2012, 22:148-155.
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 148-155
-
-
Rando, O.J.1
-
141
-
-
84880064679
-
Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types
-
Ernst J., Kellis M. Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types. Genome Res. 2013, 23:1142-1154.
-
(2013)
Genome Res.
, vol.23
, pp. 1142-1154
-
-
Ernst, J.1
Kellis, M.2
-
142
-
-
84899027001
-
Nucleosomes accelerate transcription factor dissociation
-
Luo Y., et al. Nucleosomes accelerate transcription factor dissociation. Nucleic Acids Res. 2014, 42:3017-3027.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 3017-3027
-
-
Luo, Y.1
-
143
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman R.E., et al. The accessible chromatin landscape of the human genome. Nature 2012, 489:75-82.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
-
144
-
-
79953709415
-
The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding
-
Li X.Y., et al. The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding. Genome Biol. 2011, 12:R34.
-
(2011)
Genome Biol.
, vol.12
-
-
Li, X.Y.1
-
145
-
-
84880807583
-
Absolute quantification of transcription factors during cellular differentiation using multiplexed targeted proteomics
-
Simicevic J., et al. Absolute quantification of transcription factors during cellular differentiation using multiplexed targeted proteomics. Nat. Methods 2013, 10:570-576.
-
(2013)
Nat. Methods
, vol.10
, pp. 570-576
-
-
Simicevic, J.1
-
146
-
-
84891945420
-
Widespread misinterpretable ChIP-seq bias in yeast
-
Park D., et al. Widespread misinterpretable ChIP-seq bias in yeast. PLoS ONE 2013, 8:e83506.
-
(2013)
PLoS ONE
, vol.8
-
-
Park, D.1
-
147
-
-
84887478181
-
Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins
-
Teytelman L., et al. Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:18602-18607.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 18602-18607
-
-
Teytelman, L.1
-
148
-
-
84884659690
-
Computational identification of diverse mechanisms underlying transcription factor-DNA occupancy
-
Cheng Q., et al. Computational identification of diverse mechanisms underlying transcription factor-DNA occupancy. PLoS Genet. 2013, 9:e1003571.
-
(2013)
PLoS Genet.
, vol.9
-
-
Cheng, Q.1
-
149
-
-
34250369627
-
FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin
-
Giresi P.G., et al. FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin. Genome Res. 2007, 17:877-885.
-
(2007)
Genome Res.
, vol.17
, pp. 877-885
-
-
Giresi, P.G.1
-
150
-
-
80053539409
-
Open chromatin defined by DNase I and FAIRE identifies regulatory elements that shape cell-type identity
-
Song L., et al. Open chromatin defined by DNase I and FAIRE identifies regulatory elements that shape cell-type identity. Genome Res. 2011, 21:1757-1767.
-
(2011)
Genome Res.
, vol.21
, pp. 1757-1767
-
-
Song, L.1
-
151
-
-
63849308888
-
Global mapping of protein-DNA interactions in vivo by digital genomic footprinting
-
Hesselberth J.R., et al. Global mapping of protein-DNA interactions in vivo by digital genomic footprinting. Nat. Methods 2009, 6:283-289.
-
(2009)
Nat. Methods
, vol.6
, pp. 283-289
-
-
Hesselberth, J.R.1
-
152
-
-
84888877924
-
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
-
Buenrostro J.D., et al. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat. Methods 2013, 10:1213-1218.
-
(2013)
Nat. Methods
, vol.10
, pp. 1213-1218
-
-
Buenrostro, J.D.1
-
153
-
-
84893863046
-
Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape
-
Sherwood R.I., et al. Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape. Nat. Biotechnol. 2014, 32:171-178.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 171-178
-
-
Sherwood, R.I.1
-
154
-
-
80054084614
-
Pioneer factors: directing transcriptional regulators within the chromatin environment
-
Magnani L., et al. Pioneer factors: directing transcriptional regulators within the chromatin environment. Trends Genet. 2011, 27:465-474.
-
(2011)
Trends Genet.
, vol.27
, pp. 465-474
-
-
Magnani, L.1
-
155
-
-
80455144479
-
Pioneer transcription factors: establishing competence for gene expression
-
Zaret K.S., Carroll J.S. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 2011, 25:2227-2241.
-
(2011)
Genes Dev.
, vol.25
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
156
-
-
84864428085
-
Confirming the functional importance of a protein-DNA interaction
-
Carey M.F., et al. Confirming the functional importance of a protein-DNA interaction. Cold Spring Harb. Protoc. 2012, 2012:733-757.
-
(2012)
Cold Spring Harb. Protoc.
, vol.2012
, pp. 733-757
-
-
Carey, M.F.1
-
157
-
-
84874548289
-
The relationship between long-range chromatin occupancy and polymerization of the Drosophila ETS family transcriptional repressor Yan
-
Webber J.L., et al. The relationship between long-range chromatin occupancy and polymerization of the Drosophila ETS family transcriptional repressor Yan. Genetics 2013, 193:633-649.
-
(2013)
Genetics
, vol.193
, pp. 633-649
-
-
Webber, J.L.1
-
158
-
-
84876216563
-
Master transcription factors and mediator establish super-enhancers at key cell identity genes
-
Whyte W.A., et al. Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell 2013, 153:307-319.
-
(2013)
Cell
, vol.153
, pp. 307-319
-
-
Whyte, W.A.1
-
159
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz D., et al. Super-enhancers in the control of cell identity and disease. Cell 2013, 155:934-947.
-
(2013)
Cell
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
-
160
-
-
77953992497
-
Dynamic CRM occupancy reflects a temporal map of developmental progression
-
Wilczynski B., Furlong E.E. Dynamic CRM occupancy reflects a temporal map of developmental progression. Mol. Syst. Biol. 2010, 6:383.
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 383
-
-
Wilczynski, B.1
Furlong, E.E.2
-
161
-
-
79955471381
-
High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species
-
He Q., et al. High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species. Nat. Genet. 2011, 43:414-420.
-
(2011)
Nat. Genet.
, vol.43
, pp. 414-420
-
-
He, Q.1
-
162
-
-
84884684951
-
Divergent transcriptional regulatory logic at the intersection of tissue growth and developmental patterning
-
Slattery M., et al. Divergent transcriptional regulatory logic at the intersection of tissue growth and developmental patterning. PLoS Genet. 2013, 9:e1003753.
-
(2013)
PLoS Genet.
, vol.9
-
-
Slattery, M.1
-
163
-
-
84884698724
-
Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression
-
Paris M., et al. Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression. PLoS Genet. 2013, 9:e1003748.
-
(2013)
PLoS Genet.
, vol.9
-
-
Paris, M.1
-
164
-
-
84861133568
-
A computational pipeline for comparative ChIP-seq analyses
-
Bardet A.F., et al. A computational pipeline for comparative ChIP-seq analyses. Nat. Protoc. 2012, 7:45-61.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 45-61
-
-
Bardet, A.F.1
-
165
-
-
79953046943
-
A cis-regulatory map of the Drosophila genome
-
Negre N., et al. A cis-regulatory map of the Drosophila genome. Nature 2011, 471:527-531.
-
(2011)
Nature
, vol.471
, pp. 527-531
-
-
Negre, N.1
-
166
-
-
84865754452
-
Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors
-
Yip K.Y., et al. Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors. Genome Biol. 2012, 13:R48.
-
(2012)
Genome Biol.
, vol.13
-
-
Yip, K.Y.1
-
167
-
-
84860503075
-
HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature
-
Kvon E.Z., et al. HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature. Genes Dev. 2012, 26:908-913.
-
(2012)
Genes Dev.
, vol.26
, pp. 908-913
-
-
Kvon, E.Z.1
-
168
-
-
84904267433
-
Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster
-
Slattery M., et al. Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster. Genome Res. 2014, 24:1224-1235.
-
(2014)
Genome Res.
, vol.24
, pp. 1224-1235
-
-
Slattery, M.1
-
169
-
-
84895072244
-
High-resolution mapping of transcription factor binding sites on native chromatin
-
Kasinathan S., et al. High-resolution mapping of transcription factor binding sites on native chromatin. Nat. Methods 2014, 11:203-209.
-
(2014)
Nat. Methods
, vol.11
, pp. 203-209
-
-
Kasinathan, S.1
-
170
-
-
84896338378
-
Single-molecule dynamics of enhanceosome assembly in embryonic stem cells
-
Chen J., et al. Single-molecule dynamics of enhanceosome assembly in embryonic stem cells. Cell 2014, 156:1274-1285.
-
(2014)
Cell
, vol.156
, pp. 1274-1285
-
-
Chen, J.1
-
171
-
-
3142723254
-
Biochemistry. Completing the view of transcriptional regulation
-
von Hippel P.H. Biochemistry. Completing the view of transcriptional regulation. Science 2004, 305:350-352.
-
(2004)
Science
, vol.305
, pp. 350-352
-
-
von Hippel, P.H.1
-
172
-
-
84872522659
-
Opposites attract: shape and electrostatic complementarity in protein-DNA complexes
-
Royal Society of Chemistry, T. Schlick (Ed.)
-
Harris R.C., et al. Opposites attract: shape and electrostatic complementarity in protein-DNA complexes. Innovations in Biomolecular Modeling and Simulations 2012, 53-80. Royal Society of Chemistry. T. Schlick (Ed.).
-
(2012)
Innovations in Biomolecular Modeling and Simulations
, pp. 53-80
-
-
Harris, R.C.1
-
173
-
-
84885125626
-
Positive and negative design for nonconsensus protein-DNA binding affinity in the vicinity of functional binding sites
-
Afek A., Lukatsky D.B. Positive and negative design for nonconsensus protein-DNA binding affinity in the vicinity of functional binding sites. Biophys. J. 2013, 105:1653-1660.
-
(2013)
Biophys. J.
, vol.105
, pp. 1653-1660
-
-
Afek, A.1
Lukatsky, D.B.2
-
174
-
-
84874901264
-
Genome-wide organization of eukaryotic preinitiation complex is influenced by nonconsensus protein-DNA binding
-
Afek A., Lukatsky D.B. Genome-wide organization of eukaryotic preinitiation complex is influenced by nonconsensus protein-DNA binding. Biophys. J. 2013, 104:1107-1115.
-
(2013)
Biophys. J.
, vol.104
, pp. 1107-1115
-
-
Afek, A.1
Lukatsky, D.B.2
-
175
-
-
80051862247
-
DNA sequence correlations shape nonspecific transcription factor-DNA binding affinity
-
Sela I., Lukatsky D.B. DNA sequence correlations shape nonspecific transcription factor-DNA binding affinity. Biophys. J. 2011, 101:160-166.
-
(2011)
Biophys. J.
, vol.101
, pp. 160-166
-
-
Sela, I.1
Lukatsky, D.B.2
-
176
-
-
84899799231
-
A comparative analysis of transcription factor binding models learned from PBM, HT-SELEX and ChIP data
-
Orenstein Y., Shamir R. A comparative analysis of transcription factor binding models learned from PBM, HT-SELEX and ChIP data. Nucleic Acids Res. 2014, 42:e63.
-
(2014)
Nucleic Acids Res.
, vol.42
-
-
Orenstein, Y.1
Shamir, R.2
-
177
-
-
0029617947
-
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome
-
Thanos D., Maniatis T. Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell 1995, 83:1091-1100.
-
(1995)
Cell
, vol.83
, pp. 1091-1100
-
-
Thanos, D.1
Maniatis, T.2
-
178
-
-
34249792638
-
Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer
-
Escalante C.R., et al. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Mol. Cell 2007, 26:703-716.
-
(2007)
Mol. Cell
, vol.26
, pp. 703-716
-
-
Escalante, C.R.1
-
179
-
-
1642289044
-
Coordinate enhancers share common organizational features in the Drosophila genome
-
Erives A., Levine M. Coordinate enhancers share common organizational features in the Drosophila genome. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:3851-3856.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3851-3856
-
-
Erives, A.1
Levine, M.2
-
180
-
-
56849103052
-
Evolution acts on enhancer organization to fine-tune gradient threshold readouts
-
Crocker J., et al. Evolution acts on enhancer organization to fine-tune gradient threshold readouts. PLoS Biol. 2008, 6:e263.
-
(2008)
PLoS Biol.
, vol.6
-
-
Crocker, J.1
-
181
-
-
36048995970
-
A rationale for the enhanceosome and other evolutionarily constrained enhancers
-
Papatsenko D., Levine M. A rationale for the enhanceosome and other evolutionarily constrained enhancers. Curr. Biol. 2007, 17:R955-R957.
-
(2007)
Curr. Biol.
, vol.17
-
-
Papatsenko, D.1
Levine, M.2
-
182
-
-
84864595830
-
Role of architecture in the function and specificity of two Notch-regulated transcriptional enhancer modules
-
Liu F., Posakony J.W. Role of architecture in the function and specificity of two Notch-regulated transcriptional enhancer modules. PLoS Genet. 2012, 8:e1002796.
-
(2012)
PLoS Genet.
, vol.8
-
-
Liu, F.1
Posakony, J.W.2
-
183
-
-
77950580571
-
Structural rules and complex regulatory circuitry constrain expression of a Notch- and EGFR-regulated eye enhancer
-
Swanson C.I., et al. Structural rules and complex regulatory circuitry constrain expression of a Notch- and EGFR-regulated eye enhancer. Dev. Cell 2010, 18:359-370.
-
(2010)
Dev. Cell
, vol.18
, pp. 359-370
-
-
Swanson, C.I.1
-
184
-
-
79960708456
-
Rapid evolutionary rewiring of a structurally constrained eye enhancer
-
Swanson C.I., et al. Rapid evolutionary rewiring of a structurally constrained eye enhancer. Curr. Biol. 2011, 21:1186-1196.
-
(2011)
Curr. Biol.
, vol.21
, pp. 1186-1196
-
-
Swanson, C.I.1
-
185
-
-
84884959191
-
Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development
-
Kazemian M., et al. Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development. Nucleic Acids Res. 2013, 41:8237-8252.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 8237-8252
-
-
Kazemian, M.1
-
186
-
-
84864875061
-
The cis-regulatory code of Hox function in Drosophila
-
Sorge S., et al. The cis-regulatory code of Hox function in Drosophila. EMBO J. 2012, 31:3323-3333.
-
(2012)
EMBO J.
, vol.31
, pp. 3323-3333
-
-
Sorge, S.1
-
187
-
-
17644397256
-
Transcriptional enhancers: intelligent enhanceosomes or flexible billboards?
-
Arnosti D.N., Kulkarni M.M. Transcriptional enhancers: intelligent enhanceosomes or flexible billboards?. J. Cell. Biochem. 2005, 94:890-898.
-
(2005)
J. Cell. Biochem.
, vol.94
, pp. 890-898
-
-
Arnosti, D.N.1
Kulkarni, M.M.2
-
188
-
-
0347765651
-
Information display by transcriptional enhancers
-
Kulkarni M.M., Arnosti D.N. Information display by transcriptional enhancers. Development 2003, 130:6569-6575.
-
(2003)
Development
, vol.130
, pp. 6569-6575
-
-
Kulkarni, M.M.1
Arnosti, D.N.2
-
189
-
-
84898957996
-
CCAT: Combinatorial Code Analysis Tool for transcriptional regulation
-
Jiang P., Singh M. CCAT: Combinatorial Code Analysis Tool for transcriptional regulation. Nucleic Acids Res. 2014, 42:2833-2847.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 2833-2847
-
-
Jiang, P.1
Singh, M.2
-
190
-
-
84882520699
-
Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization
-
Menoret D., et al. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Genome Biol. 2013, 14:R86.
-
(2013)
Genome Biol.
, vol.14
-
-
Menoret, D.1
-
191
-
-
84883457107
-
Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model
-
Smith R.P., et al. Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model. Nat. Genet. 2013, 45:1021-1028.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1021-1028
-
-
Smith, R.P.1
-
192
-
-
84896713460
-
Subtle changes in motif positioning cause tissue-specific effects on robustness of an enhancer's activity
-
Erceg J., et al. Subtle changes in motif positioning cause tissue-specific effects on robustness of an enhancer's activity. PLoS Genet. 2014, 10:e1004060.
-
(2014)
PLoS Genet.
, vol.10
-
-
Erceg, J.1
-
193
-
-
84856704764
-
A transcription factor collective defines cardiac cell fate and reflects lineage history
-
Junion G., et al. A transcription factor collective defines cardiac cell fate and reflects lineage history. Cell 2012, 148:473-486.
-
(2012)
Cell
, vol.148
, pp. 473-486
-
-
Junion, G.1
-
194
-
-
79955883317
-
Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators
-
Tijssen M.R., et al. Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev. Cell 2011, 20:597-609.
-
(2011)
Dev. Cell
, vol.20
, pp. 597-609
-
-
Tijssen, M.R.1
-
195
-
-
75949115944
-
Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs
-
Giorgetti L., et al. Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs. Mol. Cell 2010, 37:418-428.
-
(2010)
Mol. Cell
, vol.37
, pp. 418-428
-
-
Giorgetti, L.1
-
196
-
-
84889608617
-
Gene regulation: when analog beats digital
-
Lorberbaum D.S., Barolo S. Gene regulation: when analog beats digital. Curr. Biol. 2013, 23:R1054-R1056.
-
(2013)
Curr. Biol.
, vol.23
-
-
Lorberbaum, D.S.1
Barolo, S.2
-
197
-
-
84889582936
-
Msn2 coordinates a stoichiometric gene expression program
-
Stewart-Ornstein J., et al. Msn2 coordinates a stoichiometric gene expression program. Curr. Biol. 2013, 23:2336-2345.
-
(2013)
Curr. Biol.
, vol.23
, pp. 2336-2345
-
-
Stewart-Ornstein, J.1
-
198
-
-
84859157183
-
Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity
-
Zhang J.A., et al. Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity. Cell 2012, 149:467-482.
-
(2012)
Cell
, vol.149
, pp. 467-482
-
-
Zhang, J.A.1
-
199
-
-
84872686356
-
Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs
-
Kudron M., et al. Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs. Genome Biol. 2013, 14:R5.
-
(2013)
Genome Biol.
, vol.14
-
-
Kudron, M.1
-
200
-
-
84865773113
-
Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3
-
Frietze S., et al. Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3. Genome Biol. 2012, 13:R52.
-
(2012)
Genome Biol.
, vol.13
-
-
Frietze, S.1
-
201
-
-
84874779803
-
SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state
-
Lodato M.A., et al. SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state. PLoS Genet. 2013, 9:e1003288.
-
(2013)
PLoS Genet.
, vol.9
-
-
Lodato, M.A.1
-
202
-
-
84891792734
-
Cis-regulatory requirements for tissue-specific programs of the circadian clock
-
Meireles-Filho A.C., et al. cis-regulatory requirements for tissue-specific programs of the circadian clock. Curr. Biol. 2014, 24:1-10.
-
(2014)
Curr. Biol.
, vol.24
, pp. 1-10
-
-
Meireles-Filho, A.C.1
-
203
-
-
84868324642
-
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner
-
Gertz J., et al. Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner. Genome Res. 2012, 22:2153-2162.
-
(2012)
Genome Res.
, vol.22
, pp. 2153-2162
-
-
Gertz, J.1
-
204
-
-
84885376679
-
Distinct properties of cell-type-specific and shared transcription factor binding sites
-
Gertz J., et al. Distinct properties of cell-type-specific and shared transcription factor binding sites. Mol. Cell 2013, 52:25-36.
-
(2013)
Mol. Cell
, vol.52
, pp. 25-36
-
-
Gertz, J.1
-
205
-
-
70449132583
-
Combinatorial binding predicts spatio-temporal cis-regulatory activity
-
Zinzen R.P., et al. Combinatorial binding predicts spatio-temporal cis-regulatory activity. Nature 2009, 462:65-70.
-
(2009)
Nature
, vol.462
, pp. 65-70
-
-
Zinzen, R.P.1
-
206
-
-
78049440475
-
Chromatin landscape dictates HSF binding to target DNA elements
-
Guertin M.J., Lis J.T. Chromatin landscape dictates HSF binding to target DNA elements. PLoS Genet. 2010, 6:e1001114.
-
(2010)
PLoS Genet.
, vol.6
-
-
Guertin, M.J.1
Lis, J.T.2
-
207
-
-
77950262538
-
Nucleosome dynamics define transcriptional enhancers
-
He H.H., et al. Nucleosome dynamics define transcriptional enhancers. Nat. Genet. 2010, 42:343-347.
-
(2010)
Nat. Genet.
, vol.42
, pp. 343-347
-
-
He, H.H.1
-
208
-
-
79952184341
-
Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
-
John S., et al. Chromatin accessibility pre-determines glucocorticoid receptor binding patterns. Nat. Genet. 2011, 43:264-268.
-
(2011)
Nat. Genet.
, vol.43
, pp. 264-268
-
-
John, S.1
-
209
-
-
84882766972
-
Developmental fate and cellular maturity encoded in human regulatory DNA landscapes
-
Stergachis A.B., et al. Developmental fate and cellular maturity encoded in human regulatory DNA landscapes. Cell 2013, 154:888-903.
-
(2013)
Cell
, vol.154
, pp. 888-903
-
-
Stergachis, A.B.1
-
210
-
-
79955760882
-
Dynamic reprogramming of chromatin accessibility during Drosophila embryo development
-
Thomas S., et al. Dynamic reprogramming of chromatin accessibility during Drosophila embryo development. Genome Biol. 2011, 12:R43.
-
(2011)
Genome Biol.
, vol.12
-
-
Thomas, S.1
-
211
-
-
78650410139
-
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project
-
Gerstein M.B., et al. Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science 2010, 330:1775-1787.
-
(2010)
Science
, vol.330
, pp. 1775-1787
-
-
Gerstein, M.B.1
-
212
-
-
84896340007
-
Impacts of the ubiquitous factor Zelda on Bicoid-dependent DNA binding and transcription in Drosophila
-
Xu Z., et al. Impacts of the ubiquitous factor Zelda on Bicoid-dependent DNA binding and transcription in Drosophila. Genes Dev. 2014, 28:608-621.
-
(2014)
Genes Dev.
, vol.28
, pp. 608-621
-
-
Xu, Z.1
-
213
-
-
84867736794
-
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis
-
Xu J., et al. Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis. Dev. Cell 2012, 23:796-811.
-
(2012)
Dev. Cell
, vol.23
, pp. 796-811
-
-
Xu, J.1
-
214
-
-
0036777881
-
Molecular mechanisms of selector gene function and evolution
-
Mann R.S., Carroll S.B. Molecular mechanisms of selector gene function and evolution. Curr. Opin. Genet. Dev. 2002, 12:592-600.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 592-600
-
-
Mann, R.S.1
Carroll, S.B.2
-
215
-
-
84883445886
-
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity
-
Mazzoni E.O., et al. Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity. Nat. Neurosci. 2013, 16:1219-1227.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1219-1227
-
-
Mazzoni, E.O.1
-
216
-
-
84863649033
-
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies
-
Bresnick E.H., et al. Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res. 2012, 40:5819-5831.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 5819-5831
-
-
Bresnick, E.H.1
-
217
-
-
80051995505
-
Genetic framework for GATA factor function in vascular biology
-
Linnemann A.K., et al. Genetic framework for GATA factor function in vascular biology. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:13641-13646.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 13641-13646
-
-
Linnemann, A.K.1
-
218
-
-
84860339002
-
Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis
-
Dore L.C., et al. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood 2012, 119:3724-3733.
-
(2012)
Blood
, vol.119
, pp. 3724-3733
-
-
Dore, L.C.1
-
219
-
-
70449638281
-
Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis
-
Yu M., et al. Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol. Cell 2009, 36:682-695.
-
(2009)
Mol. Cell
, vol.36
, pp. 682-695
-
-
Yu, M.1
-
220
-
-
84865353203
-
Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression
-
Chlon T.M., et al. Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression. Mol. Cell 2012, 47:608-621.
-
(2012)
Mol. Cell
, vol.47
, pp. 608-621
-
-
Chlon, T.M.1
-
221
-
-
77957348625
-
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators
-
Wilson N.K., et al. Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell 2010, 7:532-544.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 532-544
-
-
Wilson, N.K.1
-
222
-
-
77951497999
-
GATA factor switching during erythroid differentiation
-
Kaneko H., et al. GATA factor switching during erythroid differentiation. Curr. Opin. Hematol. 2010, 17:163-168.
-
(2010)
Curr. Opin. Hematol.
, vol.17
, pp. 163-168
-
-
Kaneko, H.1
-
223
-
-
79955948338
-
Context-dependent function of 'GATA switch' sites in vivo
-
Snow J.W., et al. Context-dependent function of 'GATA switch' sites in vivo. Blood 2011, 117:4769-4772.
-
(2011)
Blood
, vol.117
, pp. 4769-4772
-
-
Snow, J.W.1
-
224
-
-
84888218999
-
The Gata1 5' region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs
-
Takai J., et al. The Gata1 5' region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs. Blood 2013, 122:3450-3460.
-
(2013)
Blood
, vol.122
, pp. 3450-3460
-
-
Takai, J.1
-
225
-
-
70449675049
-
Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy
-
Fujiwara T., et al. Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol. Cell 2009, 36:667-681.
-
(2009)
Mol. Cell
, vol.36
, pp. 667-681
-
-
Fujiwara, T.1
-
226
-
-
80053516108
-
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration
-
Wu W., et al. Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration. Genome Res. 2011, 21:1659-1671.
-
(2011)
Genome Res.
, vol.21
, pp. 1659-1671
-
-
Wu, W.1
-
227
-
-
84886716916
-
GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation
-
Suzuki M., et al. GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation. Genes Cells 2013, 18:921-933.
-
(2013)
Genes Cells
, vol.18
, pp. 921-933
-
-
Suzuki, M.1
-
228
-
-
33745209412
-
Structural basis of DNA recognition by p53 tetramers
-
Kitayner M., et al. Structural basis of DNA recognition by p53 tetramers. Mol. Cell 2006, 22:741-753.
-
(2006)
Mol. Cell
, vol.22
, pp. 741-753
-
-
Kitayner, M.1
-
229
-
-
0036307707
-
Solvent mediated interactions in the structure of the nucleosome core particle at 1.9Å resolution
-
Davey C.A., et al. Solvent mediated interactions in the structure of the nucleosome core particle at 1.9Å resolution. J. Mol. Biol. 2002, 319:1097-1113.
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 1097-1113
-
-
Davey, C.A.1
-
230
-
-
79952116707
-
Dinucleotide weight matrices for predicting transcription factor binding sites: generalizing the position weight matrix
-
Siddharthan R. Dinucleotide weight matrices for predicting transcription factor binding sites: generalizing the position weight matrix. PLoS ONE 2010, 5:e9722.
-
(2010)
PLoS ONE
, vol.5
-
-
Siddharthan, R.1
-
231
-
-
84884695174
-
The next generation of transcription factor binding site prediction
-
Mathelier A., Wasserman W.W. The next generation of transcription factor binding site prediction. PLoS Comput. Biol. 2013, 9:e1003214.
-
(2013)
PLoS Comput. Biol.
, vol.9
-
-
Mathelier, A.1
Wasserman, W.W.2
-
232
-
-
84890024582
-
A general approach for discriminative de novo motif discovery from high-throughput data
-
Grau J., et al. A general approach for discriminative de novo motif discovery from high-throughput data. Nucleic Acids Res. 2013, 41:e197.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Grau, J.1
-
233
-
-
79957562270
-
A linear model for transcription factor binding affinity prediction in protein binding microarrays
-
Annala M., et al. A linear model for transcription factor binding affinity prediction in protein binding microarrays. PLoS ONE 2011, 6:e20059.
-
(2011)
PLoS ONE
, vol.6
-
-
Annala, M.1
-
234
-
-
20744440509
-
Identification of transcription factor binding sites with variable-order Bayesian networks
-
Ben-Gal I., et al. Identification of transcription factor binding sites with variable-order Bayesian networks. Bioinformatics 2005, 21:2657-2666.
-
(2005)
Bioinformatics
, vol.21
, pp. 2657-2666
-
-
Ben-Gal, I.1
-
235
-
-
0023057575
-
Quantitative analysis of the relationship between nucleotide sequence and functional activity
-
Stormo G.D., et al. Quantitative analysis of the relationship between nucleotide sequence and functional activity. Nucleic Acids Res. 1986, 14:6661-6679.
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 6661-6679
-
-
Stormo, G.D.1
-
236
-
-
0242574990
-
A biophysical approach to transcription factor binding site discovery
-
Djordjevic M., et al. A biophysical approach to transcription factor binding site discovery. Genome Res. 2003, 13:2381-2390.
-
(2003)
Genome Res.
, vol.13
, pp. 2381-2390
-
-
Djordjevic, M.1
-
237
-
-
33748191291
-
Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE
-
Foat B.C., et al. Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE. Bioinformatics 2006, 22:e141-e149.
-
(2006)
Bioinformatics
, vol.22
-
-
Foat, B.C.1
-
238
-
-
36949023082
-
A nucleosome-guided map of transcription factor binding sites in yeast
-
Narlikar L., et al. A nucleosome-guided map of transcription factor binding sites in yeast. PLoS Comput. Biol. 2007, 3:e215.
-
(2007)
PLoS Comput. Biol.
, vol.3
-
-
Narlikar, L.1
-
239
-
-
84865856641
-
Sequence and chromatin determinants of cell-type-specific transcription factor binding
-
Arvey A., et al. Sequence and chromatin determinants of cell-type-specific transcription factor binding. Genome Res. 2012, 22:1723-1734.
-
(2012)
Genome Res.
, vol.22
, pp. 1723-1734
-
-
Arvey, A.1
-
240
-
-
0034704248
-
Genome-wide location and function of DNA binding proteins
-
Ren B., et al. Genome-wide location and function of DNA binding proteins. Science 2000, 290:2306-2309.
-
(2000)
Science
, vol.290
, pp. 2306-2309
-
-
Ren, B.1
-
241
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
Johnson D.S., et al. Genome-wide mapping of in vivo protein-DNA interactions. Science 2007, 316:1497-1502.
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
-
242
-
-
83255164884
-
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution
-
Rhee H.S., Pugh B.F. Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution. Cell 2011, 147:1408-1419.
-
(2011)
Cell
, vol.147
, pp. 1408-1419
-
-
Rhee, H.S.1
Pugh, B.F.2
-
243
-
-
33747831899
-
DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase
-
Greil F., et al. DamID: mapping of in vivo protein-genome interactions using tethered DNA adenine methyltransferase. Methods Enzymol. 2006, 410:342-359.
-
(2006)
Methods Enzymol.
, vol.410
, pp. 342-359
-
-
Greil, F.1
-
244
-
-
38649099445
-
High-resolution mapping and characterization of open chromatin across the genome
-
Boyle A.P., et al. High-resolution mapping and characterization of open chromatin across the genome. Cell 2008, 132:311-322.
-
(2008)
Cell
, vol.132
, pp. 311-322
-
-
Boyle, A.P.1
-
245
-
-
33645508729
-
Counter-selectable marker for bacterial-based interaction trap systems
-
Meng X., et al. Counter-selectable marker for bacterial-based interaction trap systems. Biotechniques 2006, 40:179-184.
-
(2006)
Biotechniques
, vol.40
, pp. 179-184
-
-
Meng, X.1
-
246
-
-
59949083631
-
Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors
-
Berger M.F., Bulyk M.L. Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors. Nat. Protoc. 2009, 4:393-411.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 393-411
-
-
Berger, M.F.1
Bulyk, M.L.2
-
247
-
-
32244448130
-
Defining the sequence-recognition profile of DNA-binding molecules
-
Warren C.L., et al. Defining the sequence-recognition profile of DNA-binding molecules. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:867-872.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 867-872
-
-
Warren, C.L.1
-
248
-
-
77956654773
-
De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis
-
Fordyce P.M., et al. De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis. Nat. Biotechnol. 2010, 28:970-975.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 970-975
-
-
Fordyce, P.M.1
-
249
-
-
41649086194
-
High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes
-
Tantin D., et al. High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes. Genome Res. 2008, 18:631-639.
-
(2008)
Genome Res.
, vol.18
, pp. 631-639
-
-
Tantin, D.1
-
250
-
-
75649122221
-
Bind-n-Seq: high-throughput analysis of in vitro protein-DNA interactions using massively parallel sequencing
-
Zykovich A., et al. Bind-n-Seq: high-throughput analysis of in vitro protein-DNA interactions using massively parallel sequencing. Nucleic Acids Res. 2009, 37:e151.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Zykovich, A.1
|