GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation

Genes to Cells

Volumn 18, Issue 11, 2013, Pages 921-933

  Suzuki, Mikiko ^a   Kobayashi Osaki, Maki ^b   Tsutsumi, Shuichi ^c   Pan, Xiaoqing ^a,d   Ohmori, Shin'ya ^a   Takai, Jun ^a   Moriguchi, Takashi ^a   Ohneda, Osamu ^b   Ohneda, Kinuko ^e   Shimizu, Ritsuko ^a   Kanki, Yasuharu ^c   Kodama, Tatsuhiko ^c   Aburatani, Hiroyuki ^c   Yamamoto, Masayuki ^a,d  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

^e TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYO; ERYTHROID CELL; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; GENE SWITCHING; HEMATOPOIETIC CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; STROMA CELL; YOLK SAC;

ANIMALS; BINDING SITES; CELL DIFFERENTIATION; ERYTHROID CELLS; ERYTHROPOIESIS; GATA1 TRANSCRIPTION FACTOR; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIETIC STEM CELLS; MICE; MICE, TRANSGENIC;

EID: 84886716916     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/gtc.12086     Document Type: Article

References (57)

1. Anderson, K.P., Crable, S.C. & Lingrel, J.B. (2000) The GATA-E box-GATA motif in the EKLF promoter is required for in vivo expression. Blood 95, 1652-1655.
2. Arceci, R.J., King, A.A., Simon, M.C., Orkin, S.H. & Wilson, D.B. (1993) Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol. Cell. Biol. 13, 2235-2246.
3. Bresnick, E.H., Lee, H.Y., Fujiwara, T., Johnson, K.D. & Keles, S. (2010) GATA switches as developmental drivers. J. Biol. Chem. 285, 31087-31093.
4. Broudy, V.C., Lin, N., Brice, M., Nakamoto, B. & Papayannopoulou, T. (1991) Erythropoietin receptor characteristics on primary human erythroid cells. Blood 77, 2583-2590.
5. Buckingham, M., Bajard, L., Chang, T., Daubas, P., Hadchouel, J., Meilhac, S., Montarras, D., Rocancourt, D. & Relaix, F. (2003) The formation of skeletal muscle: from somite to limb. J. Anat. 202, 59-68.
6. Cheng, Y., Wu, W., Kumar, S.A., et al. (2009) Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res. 19, 2172-2184.
7. Chiba, T., Ikawa, Y. & Todokoro, K. (1991) GATA-1 transactivates erythropoietin receptor gene, and erythropoietin receptor-mediated signals enhance GATA-1 gene expression. Nucleic Acids Res. 19, 3843-3848.
8. Craven, S.E., Lim, K.C., Ye, W., Engel, J.D., de Sauvage, F. & Rosenthal, A. (2004) Gata2 specifies serotonergic neurons downstream of sonic hedgehog. Development 131, 1165-1173.
9. de Vooght, K.M., van Wijk, R. & van Solinge, W.W. (2008) GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX. Gene 409, 83-91.
10. Dignam, J.D. (1990) Preparation of extracts from higher eukaryotes. Methods Enzymol. 182, 194-203.
11. Edmondson, D.G., Cheng, T.C., Cserjesi, P., Chakraborty, T. & Olson, E.N. (1992) Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2. Mol. Cell. Biol. 12, 3665-3677.
12. Evans, T. & Felsenfeld, G. (1989) The erythroid-specific transcription factor Eryf1: a new finger protein. Cell 58, 877-885.
13. Ferreira, R., Ohneda, K., Yamamoto, M. & Philipsen, S. (2005) GATA1 function, a paradigm for transcription factors in hematopoiesis. Mol. Cell. Biol. 25, 1215-1227.
14. Fujiwara, T., O'Geen, H., Keles, S., Blahnik, K., Linnemann, A.K., Kang, Y.A., Choi, K., Farnham, P.J. & Bresnick, E.H. (2009) Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol. Cell 36, 667-681.
15. Grass, J.A., Boyer, M.E., Pal, S., Wu, J., Weiss, M.J. & Bresnick, E.H. (2003) GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc. Natl Acad. Sci. USA 100, 8811-8816.
16. Gutierrez, L., Tsukamoto, S., Suzuki, M., Yamamoto-Mukai, H., Yamamoto, M., Philipsen, S. & Ohneda, K. (2008) Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady-state and stress erythropoiesis. Blood 111, 4375-4385.
17. Ito, E., Toki, T., Ishihara, H., Ohtani, H., Gu, L., Yokoyama, M., Engel, J.D. & Yamamoto, M. (1993) Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 362, 466-468.
18. Jelkmann, W. (2004) Molecular biology of erythropoietin. Intern. Med. 43, 649-659.
19. Johnson, K.D., Grass, J.A., Boyer, M.E., Kiekhaefer, C.M., Blobel, G.A., Weiss, M.J. & Bresnick, E.H. (2002) Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain. Proc. Natl Acad. Sci. USA 99, 11760-11765.
20. Kaneko, H., Shimizu, R. & Yamamoto, M. (2010) GATA factor switching during erythroid differentiation. Curr. Opin. Hematol. 17, 163-168.
21. Kaneshiro, K., Tsutsumi, S., Tsuji, S., Shirahige, K. & Aburatani, H. (2007) An integrated map of p53-binding sites and histone modification in the human ENCODE regions. Genomics 89, 178-188.
22. Kanki, Y., Kohro, T., Jiang, S., Tsutsumi, S., Mimura, I., Suehiro, J., Wada, Y., Ohta, Y., Ihara, S., Iwanari, H., Naito, M., Hamakubo, T., Aburatani, H., Kodama, T. & Minami, T. (2011) Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression. EMBO J. 30, 2582-2595.
23. Katsuoka, F., Motohashi, H., Onodera, K., Suwabe, N., Engel, J.D. & Yamamoto, M. (2000) One enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells. EMBO J. 19, 2980-2991.
24. Kelley, C., Blumberg, H., Zon, L.I. & Evans, T. (1993) GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. Development 118, 817-827.
25. Kitajima, K., Zheng, J., Yen, H., Sugiyama, D. & Nakano, T. (2006) Multipotential differentiation ability of GATA-1-null erythroid-committed cells. Genes Dev. 20, 654-659.
26. Ko, L.J. & Engel, J.D. (1993) DNA-binding specificities of the GATA transcription factor family. Mol. Cell. Biol. 13, 4011-4022.
27. Kobayashi-Osaki, M., Ohneda, O., Suzuki, N., Minegishi, N., Yokomizo, T., Takahashi, S., Lim, K.C., Engel, J.D. & Yamamoto, M. (2005) GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene. Mol. Cell. Biol. 25, 7005-7020.
28. Laverriere, A.C., MacNeill, C., Mueller, C., Poelmann, R.E., Burch, J.B. & Evans, T. (1994) GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut. J. Biol. Chem. 269, 23177-23184.
29. Martin, D.I. & Orkin, S.H. (1990) Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1. Genes Dev. 4, 1886-1898.
30. Matys, V., Fricke, E., Geffers, R., et al. (2003) TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res. 31, 374-378.
31. McDevitt, M.A., Fujiwara, Y., Shivdasani, R.A. & Orkin, S.H. (1997) An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice. Proc. Natl Acad. Sci. USA 94, 7976-7981.
32. Merika, M. & Orkin, S.H. (1993) DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13, 3999-4010.
33. Minegishi, N., Suzuki, N., Yokomizo, T., Pan, X., Fujimoto, T., Takahashi, S., Hara, T., Miyajima, A., Nishikawa, S. & Yamamoto, M. (2003) Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. Blood 102, 896-905.
34. Moroni, E., Mastrangelo, T., Razzini, R., Cairns, L., Moi, P., Ottolenghi, S. & Giglioni, B. (2000) Regulation of mouse p45 NF-E2 transcription by an erythroid-specific GATA-dependent intronic alternative promoter. J. Biol. Chem. 275, 10567-10576.
35. Mukai, H.Y., Suzuki, M., Nagano, M., Ohmori, S., Otsuki, A., Tsuchida, K., Moriguchi, T., Ohneda, K., Shimizu, R., Ohneda, O. & Yamamoto, M. (2013) Establishment of erythroleukemic GAK14 cells and characterization of GATA1 N-terminal domain. Genes Cells (in press).
36. Newman, P.J., Berndt, M.C., Gorski, J., White, G.C. 2nd, Lyman, S., Paddock, C. & Muller, W.A. (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247, 1219-1222.
37. Nishimura, S., Takahashi, S., Kuroha, T., Suwabe, N., Nagasawa, T., Trainor, C. & Yamamoto, M. (2000) A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene. Mol. Cell. Biol. 20, 713-723.
38. Onodera, K., Takahashi, S., Nishimura, S., Ohta, J., Motohashi, H., Yomogida, K., Hayashi, N., Engel, J.D. & Yamamoto, M. (1997) GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. Proc. Natl Acad. Sci. USA 94, 4487-4492.
39. Osawa, M., Hanada, K., Hamada, H. & Nakauchi, H. (1996) Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273, 242-245.
40. Pal, S., Cantor, A.B., Johnson, K.D., Moran, T.B., Boyer, M.E., Orkin, S.H. & Bresnick, E.H. (2004) Coregulator-dependent facilitation of chromatin occupancy by GATA-1. Proc. Natl Acad. Sci. USA 101, 980-985.
41. Ray, S., Dutta, D., Rumi, M.A., Kent, L.N., Soares, M.J. & Paul, S. (2009) Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation. J. Biol. Chem. 284, 4978-4988.
42. Shimizu, R., Kuroha, T., Ohneda, O., Pan, X., Ohneda, K., Takahashi, S., Philipsen, S. & Yamamoto, M. (2004) Leukemogenesis caused by incapacitated GATA-1 function. Mol. Cell. Biol. 24, 10814-10825.
43. Suzuki, M., Moriguchi, T., Ohneda, K. & Yamamoto, M. (2009) Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiation. Mol. Cell. Biol. 29, 1163-1175.
44. Suzuki, M., Ohneda, K., Hosoya-Ohmura, S., Tsukamoto, S., Ohneda, O., Philipsen, S. & Yamamoto, M. (2006a) Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic mice. Blood 108, 726-733.
45. Suzuki, N., Ohneda, O., Minegishi, N., Nishikawa, M., Ohta, T., Takahashi, S., Engel, J.D. & Yamamoto, M. (2006b) Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche. Proc. Natl Acad. Sci. USA 103, 2202-2207.
46. Suzuki, M., Shimizu, R. & Yamamoto, M. (2011) Transcriptional regulation by GATA1 and GATA2 during erythropoiesis. Int. J. Hematol. 93, 150-155.
47. Suzuki, N., Suwabe, N., Ohneda, O., Obara, N., Imagawa, S., Pan, X., Motohashi, H. & Yamamoto, M. (2003) Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels. Blood 102, 3575-3583.
48. Takahashi, S., Onodera, K., Motohashi, H., Suwabe, N., Hayashi, N., Yanai, N., Nabesima, Y. & Yamamoto, M. (1997) Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene. J. Biol. Chem. 272, 12611-12615.
49. Tapscott, S.J. (2005) The circuitry of a master switch: myod and the regulation of skeletal muscle gene transcription. Development 132, 2685-2695.
50. Tsai, F.Y. & Orkin, S.H. (1997) Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 89, 3636-3643.
51. Tsai, S.F., Martin, D.I., Zon, L.I., D'Andrea, A.D., Wong, G.G. & Orkin, S.H. (1989) Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature 339, 446-451.
52. Vyas, P., McDevitt, M.A., Cantor, A.B., Katz, S.G., Fujiwara, Y. & Orkin, S.H. (1999) Different sequence requirements for expression in erythroid and megakaryocytic cells within a regulatory element upstream of the GATA-1 gene. Development 126, 2799-2811.
53. Welch, J.J., Watts, J.A., Vakoc, C.R., Yao, Y., Wang, H., Hardison, R.C., Blobel, G.A., Chodosh, L.A. & Weiss, M.J. (2004) Global regulation of erythroid gene expression by transcription factor GATA-1. Blood 104, 3136-3147.
54. Whyatt, D.J., deBoer, E. & Grosveld, F. (1993) The two zinc finger-like domains of GATA-1 have different DNA binding specificities. EMBO J. 12, 4993-5005.
55. Yamamoto, M., Ko, L.J., Leonard, M.W., Beug, H., Orkin, S.H. & Engel, J.D. (1990) Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev. 4, 1650-1662.
56. Yu, M., Riva, L., Xie, H., Schindler, Y., Moran, T.B., Cheng, Y., Yu, D., Hardison, R., Weiss, M.J., Orkin, S.H., Bernstein, B.E., Fraenkel, E. & Cantor, A.B. (2009) Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol. Cell 36, 682-695.
57. Zon, L.I., Youssoufian, H., Mather, C., Lodish, H.F. & Orkin, S.H. (1991) Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proc. Natl Acad. Sci. USA 88, 10638-10641.