Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

Nature Neuroscience

Volumn 16, Issue 9, 2013, Pages 1219-1227

  Mazzoni, Esteban O ^a,b   Mahony, Shaun ^c,d   Closser, Michael ^a   Morrison, Carolyn A ^a   Nedelec, Stephane ^a   Williams, Damian J ^a   An, Disi ^b   Gifford, David K ^c   Wichterle, Hynek ^a  

^a Department of Medicine   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; NEUROGENIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ISL1; TRANSCRIPTION FACTOR LHX3; TRANSCRIPTION FACTOR PHOX2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL FATE; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; CRANIAL NERVE; EMBRYO; EMBRYONIC STEM CELL; ENHANCER REGION; GENE EXPRESSION; GENE LOCATION; MOTONEURON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SPINAL CORD MOTONEURON;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELLS, CULTURED; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HOMEODOMAIN PROTEINS; KI-67 ANTIGEN; LIM-HOMEODOMAIN PROTEINS; MICE; MOTOR NEURONS; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SPINAL CORD; STEM CELLS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84883445886     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3467     Document Type: Article

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