The Gata1 5′ region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs

Blood

Volumn 122, Issue 20, 2013, Pages 3450-3460

  Takai, Jun ^a   Moriguchi, Takashi ^a   Suzuki, Mikiko ^a   Yu, Lei ^a   Ohneda, Kinuko ^b   Yamamoto, Masayuki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; DNA; DNA METHYLTRANSFERASE 1; GREEN FLUORESCENT PROTEIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; GATA1 PROTEIN, MOUSE; GATA2 PROTEIN, MOUSE; SYNTHETIC DNA;

5' UNTRANSLATED REGION; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYONIC STEM CELL; ENHANCER REGION; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; GENE ACTIVATION; GENE EXPRESSION; GENE INACTIVATION; GENE SEQUENCE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN MOTIF; REPORTER GENE; TRANSGENIC MOUSE; ANIMAL; BACTERIAL ARTIFICIAL CHROMOSOME; CELL CULTURE; CELL LINEAGE; CYTOLOGY; EMBRYOLOGY; ERYTHROPOIESIS; GENE DELETION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; LIVER; METABOLISM; NUCLEOTIDE MOTIF; PHYSIOLOGY; REGULATORY SEQUENCE; TRANSCRIPTION INITIATION;

ANIMALS; CELL LINEAGE; CELLS, CULTURED; CHROMOSOMES, ARTIFICIAL, BACTERIAL; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; ENHANCER ELEMENTS, GENETIC; ERYTHROID CELLS; ERYTHROPOIESIS; GATA1 TRANSCRIPTION FACTOR; GATA2 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; GENES, REPORTER; GENES, SYNTHETIC; HEMATOPOIETIC STEM CELLS; LIVER; MEGAKARYOCYTES; MICE; MICE, TRANSGENIC; NUCLEOTIDE MOTIFS; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE DELETION; TRANSCRIPTIONAL ACTIVATION;

EID: 84888218999     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-01-476911     Document Type: Article

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