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Volumn 129, Issue 6, 2007, Pages 1111-1123

An Atomic Model of the Interferon-β Enhanceosome

Author keywords

DEVBIO; DNA; PROTEINS

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; BETA INTERFERON; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; ENHANCEOSOME; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; MEMBRANE PROTEIN; NUCLEOTIDE; PROTEIN C JUN; TRANSCRIPTION FACTOR;

EID: 34250017968     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2007.05.019     Document Type: Article
Times cited : (487)

References (59)
  • 1
    • 0033681250 scopus 로고    scopus 로고
    • Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter
    • Agalioti T., Lomvardas S., Parekh B., Yie J., Maniatis T., and Thanos D. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell 103 (2000) 667-678
    • (2000) Cell , vol.103 , pp. 667-678
    • Agalioti, T.1    Lomvardas, S.2    Parekh, B.3    Yie, J.4    Maniatis, T.5    Thanos, D.6
  • 2
    • 17644397256 scopus 로고    scopus 로고
    • Transcriptional enhancers: Intelligent enhanceosomes or flexible billboards?
    • Arnosti D.N., and Kulkarni M.M. Transcriptional enhancers: Intelligent enhanceosomes or flexible billboards?. J. Cell. Biochem. 94 (2005) 890-898
    • (2005) J. Cell. Biochem. , vol.94 , pp. 890-898
    • Arnosti, D.N.1    Kulkarni, M.M.2
  • 3
    • 0029585553 scopus 로고
    • Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro
    • Bannister A.J., Oehler T., Wilhelm D., Angel P., and Kouzarides T. Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene 11 (1995) 2509-2514
    • (1995) Oncogene , vol.11 , pp. 2509-2514
    • Bannister, A.J.1    Oehler, T.2    Wilhelm, D.3    Angel, P.4    Kouzarides, T.5
  • 4
    • 0037025364 scopus 로고    scopus 로고
    • The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site
    • Berkowitz B., Huang D.B., Chen-Park F.E., Sigler P.B., and Ghosh G. The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. J. Biol. Chem. 277 (2002) 24694-24700
    • (2002) J. Biol. Chem. , vol.277 , pp. 24694-24700
    • Berkowitz, B.1    Huang, D.B.2    Chen-Park, F.E.3    Sigler, P.B.4    Ghosh, G.5
  • 7
    • 0033596120 scopus 로고    scopus 로고
    • Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views
    • Chen F.E., and Ghosh G. Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views. Oncogene 18 (1999) 6845-6852
    • (1999) Oncogene , vol.18 , pp. 6845-6852
    • Chen, F.E.1    Ghosh, G.2
  • 8
    • 0032556894 scopus 로고    scopus 로고
    • Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA
    • Chen F.E., Huang D.B., Chen Y.Q., and Ghosh G. Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature 391 (1998) 410-413
    • (1998) Nature , vol.391 , pp. 410-413
    • Chen, F.E.1    Huang, D.B.2    Chen, Y.Q.3    Ghosh, G.4
  • 9
    • 0032485391 scopus 로고    scopus 로고
    • Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA
    • Chen L., Glover J.N., Hogan P.G., Rao A., and Harrison S.C. Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature 392 (1998) 42-48
    • (1998) Nature , vol.392 , pp. 42-48
    • Chen, L.1    Glover, J.N.2    Hogan, P.G.3    Rao, A.4    Harrison, S.C.5
  • 10
    • 0037025395 scopus 로고    scopus 로고
    • The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription
    • Chen-Park F.E., Huang D.B., Noro B., Thanos D., and Ghosh G. The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription. J. Biol. Chem. 277 (2002) 24701-24708
    • (2002) J. Biol. Chem. , vol.277 , pp. 24701-24708
    • Chen-Park, F.E.1    Huang, D.B.2    Noro, B.3    Thanos, D.4    Ghosh, G.5
  • 11
    • 0026604277 scopus 로고
    • An ATF/CREB binding site is required for virus induction of the human interferon-β gene
    • Du W., and Maniatis T. An ATF/CREB binding site is required for virus induction of the human interferon-β gene. Proc. Natl. Acad. Sci. USA 89 (1992) 2150-2154
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2150-2154
    • Du, W.1    Maniatis, T.2
  • 13
    • 0031933646 scopus 로고    scopus 로고
    • Structure of IRF-1 with bound DNA reveals determinants of interferon regulation
    • Escalante C.R., Yie J., Thanos D., and Aggarwal A.K. Structure of IRF-1 with bound DNA reveals determinants of interferon regulation. Nature 391 (1998) 103-106
    • (1998) Nature , vol.391 , pp. 103-106
    • Escalante, C.R.1    Yie, J.2    Thanos, D.3    Aggarwal, A.K.4
  • 15
    • 0036124647 scopus 로고    scopus 로고
    • Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter
    • Escalante C.R., Shen L., Thanos D., and Aggarwal A.K. Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter. Structure 10 (2002) 383-391
    • (2002) Structure , vol.10 , pp. 383-391
    • Escalante, C.R.1    Shen, L.2    Thanos, D.3    Aggarwal, A.K.4
  • 16
    • 34249792638 scopus 로고    scopus 로고
    • Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-β enhancer
    • Escalante C.R., Nistal-Villán E., Shen L., García-Sastre A., and Aggarwal A.K. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-β enhancer. Mol. Cell 26 (2007) 703-716
    • (2007) Mol. Cell , vol.26 , pp. 703-716
    • Escalante, C.R.1    Nistal-Villán, E.2    Shen, L.3    García-Sastre, A.4    Aggarwal, A.K.5
  • 17
    • 0029619641 scopus 로고
    • Reversal of intrinsic DNA bends in the IFN beta gene enhancer by transcription factors and the architectural protein HMG I(Y)
    • Falvo J.V., Thanos D., and Maniatis T. Reversal of intrinsic DNA bends in the IFN beta gene enhancer by transcription factors and the architectural protein HMG I(Y). Cell 83 (1995) 1101-1111
    • (1995) Cell , vol.83 , pp. 1101-1111
    • Falvo, J.V.1    Thanos, D.2    Maniatis, T.3
  • 18
    • 0034122095 scopus 로고    scopus 로고
    • Assembly of a functional beta interferon enhanceosome is dependent on ATF-2/c-Jun heterodimer orientation
    • Falvo J.V., Parekh B.S., Lin C.H., Fraenkel E., and Maniatis T. Assembly of a functional beta interferon enhanceosome is dependent on ATF-2/c-Jun heterodimer orientation. Mol. Cell. Biol. 20 (2000) 4814-4825
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4814-4825
    • Falvo, J.V.1    Parekh, B.S.2    Lin, C.H.3    Fraenkel, E.4    Maniatis, T.5
  • 19
    • 0033568642 scopus 로고    scopus 로고
    • Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences
    • Fujii Y., Shimizu T., Kusumoto M., Kyogoku Y., Taniguchi T., and Hakoshima T. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. EMBO J. 18 (1999) 5028-5041
    • (1999) EMBO J. , vol.18 , pp. 5028-5041
    • Fujii, Y.1    Shimizu, T.2    Kusumoto, M.3    Kyogoku, Y.4    Taniguchi, T.5    Hakoshima, T.6
  • 20
    • 0024114474 scopus 로고
    • Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-beta gene regulatory elements
    • Fujita T., Sakakibara J., Sudo Y., Miyamoto M., Kimura Y., and Taniguchi T. Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-beta gene regulatory elements. EMBO J. 7 (1988) 3397-3405
    • (1988) EMBO J. , vol.7 , pp. 3397-3405
    • Fujita, T.1    Sakakibara, J.2    Sudo, Y.3    Miyamoto, M.4    Kimura, Y.5    Taniguchi, T.6
  • 21
    • 0028979479 scopus 로고
    • Structure of NF-kappa B p50 homodimer bound to a kappa B site
    • Ghosh G., van Duyne G., Ghosh S., and Sigler P.B. Structure of NF-kappa B p50 homodimer bound to a kappa B site. Nature 373 (1995) 303-310
    • (1995) Nature , vol.373 , pp. 303-310
    • Ghosh, G.1    van Duyne, G.2    Ghosh, S.3    Sigler, P.B.4
  • 22
    • 0023931312 scopus 로고
    • Overlapping positive and negative regulatory domains of the human beta-interferon gene
    • Goodbourn S., and Maniatis T. Overlapping positive and negative regulatory domains of the human beta-interferon gene. Proc. Natl. Acad. Sci. USA 85 (1988) 1447-1451
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1447-1451
    • Goodbourn, S.1    Maniatis, T.2
  • 25
    • 84889120137 scopus 로고
    • Improved methods for building protein models in electron density maps and the location of errors in these models
    • Jones T.A., Zou J.Y., Cowan S.W., and Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47 (1991) 110-119
    • (1991) Acta Crystallogr. A , vol.47 , pp. 110-119
    • Jones, T.A.1    Zou, J.Y.2    Cowan, S.W.3    Kjeldgaard, M.4
  • 26
    • 0031985052 scopus 로고    scopus 로고
    • p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells
    • Kawasaki H., Song J., Eckner R., Ugai H., Chiu R., Taira K., Shi Y., Jones N., and Yokoyama K.K. p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes Dev. 12 (1998) 233-245
    • (1998) Genes Dev. , vol.12 , pp. 233-245
    • Kawasaki, H.1    Song, J.2    Eckner, R.3    Ugai, H.4    Chiu, R.5    Taira, K.6    Shi, Y.7    Jones, N.8    Yokoyama, K.K.9
  • 27
    • 0030025170 scopus 로고    scopus 로고
    • Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage
    • Klemm J.D., and Pabo C.O. Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage. Genes Dev. 10 (1996) 27-36
    • (1996) Genes Dev. , vol.10 , pp. 27-36
    • Klemm, J.D.1    Pabo, C.O.2
  • 28
    • 0024058085 scopus 로고
    • The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids
    • Lavery R., and Sklenar H. The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids. J. Biomol. Struct. Dyn. 6 (1988) 63-91
    • (1988) J. Biomol. Struct. Dyn. , vol.6 , pp. 63-91
    • Lavery, R.1    Sklenar, H.2
  • 29
    • 0034785837 scopus 로고    scopus 로고
    • A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies
    • Lin C.H., Hare B.J., Wagner G., Harrison S.C., Maniatis T., and Fraenkel E. A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies. Mol. Cell 8 (2001) 581-590
    • (2001) Mol. Cell , vol.8 , pp. 581-590
    • Lin, C.H.1    Hare, B.J.2    Wagner, G.3    Harrison, S.C.4    Maniatis, T.5    Fraenkel, E.6
  • 30
    • 0033842515 scopus 로고    scopus 로고
    • Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7
    • Lin R., Genin P., Mamane Y., and Hiscott J. Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 20 (2000) 6342-6353
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6342-6353
    • Lin, R.1    Genin, P.2    Mamane, Y.3    Hiscott, J.4
  • 31
    • 0031893220 scopus 로고    scopus 로고
    • Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
    • Lin R., Heylbroeck C., Pitha P.M., and Hiscott J. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol. Cell. Biol. 18 (1998) 2986-2996
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2986-2996
    • Lin, R.1    Heylbroeck, C.2    Pitha, P.M.3    Hiscott, J.4
  • 32
    • 0035929147 scopus 로고    scopus 로고
    • Nucleosome sliding via TBP DNA binding in vivo
    • Lomvardas S., and Thanos D. Nucleosome sliding via TBP DNA binding in vivo. Cell 106 (2001) 685-696
    • (2001) Cell , vol.106 , pp. 685-696
    • Lomvardas, S.1    Thanos, D.2
  • 33
    • 0242396923 scopus 로고    scopus 로고
    • 3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures
    • Lu X.J., and Olson W.K. 3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures. Nucleic Acids Res. 31 (2003) 5108-5121
    • (2003) Nucleic Acids Res. , vol.31 , pp. 5108-5121
    • Lu, X.J.1    Olson, W.K.2
  • 34
    • 0034598832 scopus 로고    scopus 로고
    • Evidence for stabilizing selection in a eukaryotic enhancer element
    • Ludwig M.Z., Bergman C., Patel N.H., and Kreitman M. Evidence for stabilizing selection in a eukaryotic enhancer element. Nature 403 (2000) 564-567
    • (2000) Nature , vol.403 , pp. 564-567
    • Ludwig, M.Z.1    Bergman, C.2    Patel, N.H.3    Kreitman, M.4
  • 36
    • 0031574026 scopus 로고    scopus 로고
    • NUCPLOT: a program to generate schematic diagrams of protein-nucleic acid interactions
    • Luscombe N.M., Laskowski R.A., and Thornton J.M. NUCPLOT: a program to generate schematic diagrams of protein-nucleic acid interactions. Nucleic Acids Res. 25 (1997) 4940-4945
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4940-4945
    • Luscombe, N.M.1    Laskowski, R.A.2    Thornton, J.M.3
  • 39
    • 0032538891 scopus 로고    scopus 로고
    • Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
    • Marie I., Durbin J.E., and Levy D.E. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J. 17 (1998) 6660-6669
    • (1998) EMBO J. , vol.17 , pp. 6660-6669
    • Marie, I.1    Durbin, J.E.2    Levy, D.E.3
  • 41
    • 0031604766 scopus 로고    scopus 로고
    • Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription
    • Merika M., Williams A.J., Chen G., Collins T., and Thanos D. Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription. Mol. Cell 1 (1998) 277-287
    • (1998) Mol. Cell , vol.1 , pp. 277-287
    • Merika, M.1    Williams, A.J.2    Chen, G.3    Collins, T.4    Thanos, D.5
  • 42
    • 0036308245 scopus 로고    scopus 로고
    • Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription
    • Morin P., Braganca J., Bandu M.T., Lin R., Hiscott J., Doly J., and Civas A. Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription. J. Mol. Biol. 316 (2002) 1009-1022
    • (2002) J. Mol. Biol. , vol.316 , pp. 1009-1022
    • Morin, P.1    Braganca, J.2    Bandu, M.T.3    Lin, R.4    Hiscott, J.5    Doly, J.6    Civas, A.7
  • 45
  • 46
    • 10044239268 scopus 로고    scopus 로고
    • Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer
    • Panne D., Maniatis T., and Harrison S.C. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer. EMBO J. 23 (2004) 4384-4393
    • (2004) EMBO J. , vol.23 , pp. 4384-4393
    • Panne, D.1    Maniatis, T.2    Harrison, S.C.3
  • 47
    • 0004211673 scopus 로고    scopus 로고
    • Cold Spring Harbor Laboratory Press, New York
    • Ptashne M., and Gann A. Genes and Signals (2002), Cold Spring Harbor Laboratory Press, New York
    • (2002) Genes and Signals
    • Ptashne, M.1    Gann, A.2
  • 49
    • 0032434924 scopus 로고    scopus 로고
    • Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
    • Sato M., Hata N., Asagiri M., Nakaya T., Taniguchi T., and Tanaka N. Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. FEBS Lett. 441 (1998) 106-110
    • (1998) FEBS Lett. , vol.441 , pp. 106-110
    • Sato, M.1    Hata, N.2    Asagiri, M.3    Nakaya, T.4    Taniguchi, T.5    Tanaka, N.6
  • 50
    • 0033680737 scopus 로고    scopus 로고
    • Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
    • Sato M., Suemori H., Hata N., Asagiri M., Ogasawara K., Nakao K., Nakaya T., Katsuki M., Noguchi S., Tanaka N., et al. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13 (2000) 539-548
    • (2000) Immunity , vol.13 , pp. 539-548
    • Sato, M.1    Suemori, H.2    Hata, N.3    Asagiri, M.4    Ogasawara, K.5    Nakao, K.6    Nakaya, T.7    Katsuki, M.8    Noguchi, S.9    Tanaka, N.10
  • 51
    • 0025865166 scopus 로고
    • Transcriptional regulation of a pair-rule stripe in Drosophila
    • Small S., Kraut R., Hoey T., Warrior R., and Levine M. Transcriptional regulation of a pair-rule stripe in Drosophila. Genes Dev. 5 (1991) 827-839
    • (1991) Genes Dev. , vol.5 , pp. 827-839
    • Small, S.1    Kraut, R.2    Hoey, T.3    Warrior, R.4    Levine, M.5
  • 52
    • 0035838995 scopus 로고    scopus 로고
    • Gene regulation. A paradigm for precision
    • Struhl K. Gene regulation. A paradigm for precision. Science 293 (2001) 1054-1055
    • (2001) Science , vol.293 , pp. 1054-1055
    • Struhl, K.1
  • 53
    • 0026489365 scopus 로고
    • The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene
    • Thanos D., and Maniatis T. The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta gene. Cell 71 (1992) 777-789
    • (1992) Cell , vol.71 , pp. 777-789
    • Thanos, D.1    Maniatis, T.2
  • 54
    • 0029617947 scopus 로고
    • Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome
    • Thanos D., and Maniatis T. Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell 83 (1995) 1091-1100
    • (1995) Cell , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 55
    • 0027893397 scopus 로고
    • The high mobility group protein HMG I(Y) is an essential structural component of a virus-inducible enhancer complex
    • Thanos D., Du W., and Maniatis T. The high mobility group protein HMG I(Y) is an essential structural component of a virus-inducible enhancer complex. Cold Spring Harb. Symp. Quant. Biol. 58 (1993) 73-81
    • (1993) Cold Spring Harb. Symp. Quant. Biol. , vol.58 , pp. 73-81
    • Thanos, D.1    Du, W.2    Maniatis, T.3
  • 56
    • 0034741833 scopus 로고    scopus 로고
    • HMG1 and 2: architectural DNA-binding proteins
    • Thomas J.O. HMG1 and 2: architectural DNA-binding proteins. Biochem. Soc. Trans. 29 (2001) 395-401
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 395-401
    • Thomas, J.O.1
  • 57
    • 0000560808 scopus 로고    scopus 로고
    • MOLREP: an automated program for molecular replacement
    • Vagin A., and Teplyakov A. MOLREP: an automated program for molecular replacement. J. Appl. Crystallogr. 30 (1997) 1022-1025
    • (1997) J. Appl. Crystallogr. , vol.30 , pp. 1022-1025
    • Vagin, A.1    Teplyakov, A.2
  • 58
    • 0032015647 scopus 로고    scopus 로고
    • Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
    • Wathelet M.G., Lin C.H., Parekh B.S., Ronco L.V., Howley P.M., and Maniatis T. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol. Cell 1 (1998) 507-518
    • (1998) Mol. Cell , vol.1 , pp. 507-518
    • Wathelet, M.G.1    Lin, C.H.2    Parekh, B.S.3    Ronco, L.V.4    Howley, P.M.5    Maniatis, T.6
  • 59
    • 0033539575 scopus 로고    scopus 로고
    • Mechanism by which the IFN-beta enhanceosome activates transcription
    • Yie J., Senger K., and Thanos D. Mechanism by which the IFN-beta enhanceosome activates transcription. Proc. Natl. Acad. Sci. USA 96 (1999) 13108-13113
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 13108-13113
    • Yie, J.1    Senger, K.2    Thanos, D.3


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