A systems approach to measuring the binding energy landscapes of transcription factors

Science

Volumn 315, Issue 5809, 2007, Pages 233-237

  Maerkl, Sebastian J ^a,b   Quake, Stephen R ^b  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAX PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CBF1P; TRANSCRIPTION FACTOR PHO4P; UNCLASSIFIED DRUG;

DNA; EUKARYOTE; MOLECULAR ANALYSIS; TOPOLOGY;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; DNA SEQUENCE; HUMAN; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SYSTEMS BIOLOGY;

BASE SEQUENCE; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DNA; DNA, FUNGAL; DNA-BINDING PROTEINS; E-BOX ELEMENTS; GENE EXPRESSION REGULATION, FUNGAL; HELIX-LOOP-HELIX MOTIFS; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; PROTEIN ISOFORMS; REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SYSTEMS BIOLOGY; TEMPLATES, GENETIC; THERMODYNAMICS; TRANSCRIPTION FACTORS;

EUKARYOTA;

EID: 33846467150     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1131007     Document Type: Article

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