-
1
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, et al. 1997. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275:1943-47
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
-
2
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, et al. 1997. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15:356-62
-
(1997)
Nat. Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
-
3
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Li J, Dahia PL, Wang SI, et al. 1997. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16:64-67
-
(1997)
Nat. Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
-
4
-
-
0031985674
-
Phosphatases and tumorigenesis
-
Parsons R. 1998. Phosphatases and tumorigenesis. Curr. Opin. Oncol. 10:88-91
-
(1998)
Curr. Opin. Oncol
, vol.10
, pp. 88-91
-
-
Parsons, R.1
-
5
-
-
7344227886
-
Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers
-
Cairns P, Evron E, Okami K, Halachmi N, Esteller M, et al. 1998. Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers. Oncogene 16:3215-18
-
(1998)
Oncogene
, vol.16
, pp. 3215-3218
-
-
Cairns, P.1
Evron, E.2
Okami, K.3
Halachmi, N.4
Esteller, M.5
-
6
-
-
7144223432
-
PTEN mutations in gliomas and glioneuronal tumors
-
Duerr EM, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, et al. 1998. PTEN mutations in gliomas and glioneuronal tumors. Oncogene 16:2259-64
-
(1998)
Oncogene
, vol.16
, pp. 2259-2264
-
-
Duerr, E.M.1
Rollbrocker, B.2
Hayashi, Y.3
Peters, N.4
Meyer-Puttlitz, B.5
-
7
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
Suzuki A, de la Pompa JL, Stambolic V, Elia AJ, Sasaki T, et al. 1998. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr. Biol. 8:1169-78
-
(1998)
Curr. Biol
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
De La Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
-
9
-
-
84862208776
-
Functional analysis of the protein phosphatase activity of PTEN
-
Zhang XC, Piccini A, Myers MP, Van Aelst L, Tonks NK. 2012. Functional analysis of the protein phosphatase activity of PTEN. Biochem. J. 444:457-64
-
(2012)
Biochem. J
, vol.444
, pp. 457-464
-
-
Zhang, X.C.1
Piccini, A.2
Myers, M.P.3
Van Aelst, L.4
Tonks, N.K.5
-
10
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor ?
-
Li DM, Sun H. 1997. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor ?. Cancer Res. 57:2124-29
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
11
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM. 1998. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280:1614-17
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
12
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers MP, Stolarov JP, Eng C, Li J, Wang SI, et al. 1997. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc. Natl. Acad. Sci. USA 94:9052-57
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
-
13
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273:13375-78
-
(1998)
J. Biol. Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
14
-
-
0032904432
-
PTEN: A tumour suppressor that functions as a phospholipid phosphatase
-
Maehama T,Dixon JE. 1999. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol. 9:125-28
-
(1999)
Trends Cell Biol
, vol.9
, pp. 125-128
-
-
Maehama, T.1
Dixon, J.E.2
-
15
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
-
Myers MP, Pass I, Batty IH, Van der Kaay J, Stolarov JP, et al. 1998. The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc. Natl. Acad. Sci. USA 95:13513-18
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van Der Kaay, J.4
Stolarov, J.P.5
-
16
-
-
0023665111
-
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity
-
Kaplan DR,Whitman M, Schaffhausen B, Pallas DC,White M, et al. 1987. Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell 50:1021-29
-
(1987)
Cell
, vol.50
, pp. 1021-1029
-
-
Kaplan, D.R.1
Whitman, M.2
Schaffhausen, B.3
Pallas, D.C.4
White, M.5
-
17
-
-
0021828496
-
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
-
Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315:239-42
-
(1985)
Nature
, vol.315
, pp. 239-242
-
-
Whitman, M.1
Kaplan, D.R.2
Schaffhausen, B.3
Cantley, L.4
Roberts, T.M.5
-
18
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman JA, Luo J, Cantley LC. 2006. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 7:606-19
-
(2006)
Nat. Rev. Genet
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
20
-
-
70350405643
-
Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation
-
Zhang TT, Li H, Cheung SM, Costantini JL, Hou S, et al. 2009. Phosphoinositide 3-kinase-regulated adapters in lymphocyte activation. Immunol. Rev. 232:255-72
-
(2009)
Immunol. Rev
, vol.232
, pp. 255-272
-
-
Zhang, T.T.1
Li, H.2
Cheung, S.M.3
Costantini, J.L.4
Hou, S.5
-
21
-
-
84868122919
-
PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells
-
Hunzicker-DunnME, Lopez-Biladeau B, Law NC, Fiedler SE, Carr DW, Maizels ET. 2012. PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells. Proc. Natl. Acad. Sci. USA 109:E2979-88
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
-
-
Hunzicker-Dunn, M.E.1
Lopez-Biladeau, B.2
Law, N.C.3
Fiedler, S.E.4
Carr, D.W.5
Maizels, E.T.6
-
22
-
-
84879184496
-
Phosphatidylinositol-3,4,5-trisphosphate: Tool of choice for class i PI 3-kinases
-
Salamon RS, Backer JM. 2013. Phosphatidylinositol-3,4,5-trisphosphate: tool of choice for class I PI 3-kinases. BioEssays 35:602-11
-
(2013)
BioEssays
, vol.35
, pp. 602-611
-
-
Salamon, R.S.1
Backer, J.M.2
-
23
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. 2002. The phosphoinositide 3-kinase pathway. Science 296:1655-57
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
25
-
-
0036849331
-
PKB binding proteins. Getting in on the Akt
-
Brazil DP, Park J, Hemmings BA. 2002. PKB binding proteins. Getting in on the Akt. Cell 111:293-303
-
(2002)
Cell
, vol.111
, pp. 293-303
-
-
Brazil, D.P.1
Park, J.2
Hemmings, B.A.3
-
26
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC. 2007. AKT/PKB signaling: navigating downstream. Cell 129:1261-74
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
27
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin DA, Sabatini DM. 2007. Defining the role of mTOR in cancer. Cancer Cell 12:9-22
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
28
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:262-67
-
(1998)
Curr. Opin. Cell Biol
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
29
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, et al. 1998. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95:29-39
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
-
30
-
-
0032534963
-
The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene
-
Li J, Simpson L, Takahashi M, Miliaresis C, Myers MP, et al. 1998. The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Res. 58:5667-72
-
(1998)
Cancer Res
, vol.58
, pp. 5667-5672
-
-
Li, J.1
Simpson, L.2
Takahashi, M.3
Miliaresis, C.4
Myers, M.P.5
-
31
-
-
34548643512
-
Phosphoinositide phosphatases in a network of signalling reactions
-
Blero D, Payrastre B, Schurmans S, Erneux C. 2007. Phosphoinositide phosphatases in a network of signalling reactions. Pflüg. Arch. 455:31-44
-
(2007)
Pflüg. Arch
, vol.455
, pp. 31-44
-
-
Blero, D.1
Payrastre, B.2
Schurmans, S.3
Erneux, C.4
-
32
-
-
33749836234
-
Phosphoinositides in cell regulation and membrane dynamics
-
Di Paolo G, De Camilli P. 2006. Phosphoinositides in cell regulation and membrane dynamics. Nature 443:651-57
-
(2006)
Nature
, vol.443
, pp. 651-657
-
-
Di Paolo, G.1
De Camilli, P.2
-
33
-
-
84870017064
-
An introduction to phosphoinositides
-
Maffucci T. 2012. An introduction to phosphoinositides. Curr. Top. Microbiol. Immunol. 362:1-42
-
(2012)
Curr. Top. Microbiol. Immunol
, vol.362
, pp. 1-42
-
-
Maffucci, T.1
-
34
-
-
0028533592
-
Tensin: A potential link between the cytoskeleton and signal transduction
-
Lo SH, Weisberg E, Chen LB. 1994. Tensin: a potential link between the cytoskeleton and signal transduction. BioEssays 16:817-23
-
(1994)
BioEssays
, vol.16
, pp. 817-823
-
-
Lo, S.H.1
Weisberg, E.2
Chen, L.B.3
-
35
-
-
0035128240
-
Expression of auxilin or AP180 inhibits endocytosis bymislocalizing clathrin: Evidence for formation of nascent pits containing AP1 or AP2 but not clathrin
-
Zhao X, Greener T, Al-Hasani H, Cushman SW, Eisenberg E, Greene LE. 2001. Expression of auxilin or AP180 inhibits endocytosis bymislocalizing clathrin: evidence for formation of nascent pits containing AP1 or AP2 but not clathrin. J. Cell Sci. 114:353-65
-
(2001)
J. Cell Sci
, vol.114
, pp. 353-365
-
-
Zhao, X.1
Greener, T.2
Al-Hasani, H.3
Cushman, S.W.4
Eisenberg, E.5
Greene, L.E.6
-
36
-
-
0029975476
-
Crystal structure of the dual specificity protein phosphatase VHR
-
Yuvaniyama J, Denu JM, Dixon JE, Saper MA. 1996. Crystal structure of the dual specificity protein phosphatase VHR. Science 272:1328-31
-
(1996)
Science
, vol.272
, pp. 1328-1331
-
-
Yuvaniyama, J.1
Denu, J.M.2
Dixon, J.E.3
Saper, M.A.4
-
37
-
-
0033615538
-
Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
-
Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, et al. 1999. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99:323-34
-
(1999)
Cell
, vol.99
, pp. 323-334
-
-
Lee, J.O.1
Yang, H.2
Georgescu, M.M.3
Di Cristofano, A.4
Maehama, T.5
-
39
-
-
0033822632
-
Genomic structure of a copy of the human TPTE gene which encompasses 87 kb on the short arm of chromosome 21
-
Guipponi M, Yaspo ML, Riesselman L, Chen H, De Sario A, et al. 2000. Genomic structure of a copy of the human TPTE gene which encompasses 87 kb on the short arm of chromosome 21. Hum. Genet. 107:127-31
-
(2000)
Hum. Genet
, vol.107
, pp. 127-131
-
-
Guipponi, M.1
Yaspo, M.L.2
Riesselman, L.3
Chen, H.4
De Sario, A.5
-
40
-
-
0345059066
-
The TPTE gene family: Cellular expression, subcellular localization and alternative splicing
-
Tapparel C, Reymond A, Girardet C, Guillou L, Lyle R, et al. 2003. The TPTE gene family: cellular expression, subcellular localization and alternative splicing. Gene 323:189-99
-
(2003)
Gene
, vol.323
, pp. 189-199
-
-
Tapparel, C.1
Reymond, A.2
Girardet, C.3
Guillou, L.4
Lyle, R.5
-
41
-
-
0032706145
-
A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and y
-
Chen H, Rossier C, Morris MA, Scott HS, Gos A, et al. 1999. A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y. Hum. Genet. 105:399-409
-
(1999)
Hum. Genet
, vol.105
, pp. 399-409
-
-
Chen, H.1
Rossier, C.2
Morris, M.A.3
Scott, H.S.4
Gos, A.5
-
42
-
-
0035605844
-
TPIP: A novel phosphoinositide 3-phosphatase
-
Walker SM, Downes CP, Leslie NR. 2001. TPIP: a novel phosphoinositide 3-phosphatase. Biochem. J. 360:277-83
-
(2001)
Biochem. J
, vol.360
, pp. 277-283
-
-
Walker, S.M.1
Downes, C.P.2
Leslie, N.R.3
-
43
-
-
82555202982
-
A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells
-
Mishra RR, Chaudhary JK, Bajaj GD, Rath PC. 2011. A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells. PLoS ONE 6:e28433
-
(2011)
PLoS ONE
, vol.6
-
-
Mishra, R.R.1
Chaudhary, J.K.2
Bajaj, G.D.3
Rath, P.C.4
-
44
-
-
84864286604
-
Cell cycle arrest and apoptosis by expression of a novel TPIP (TPIP-C2) cDNA encoding a C2-domain in HEK-293 cells
-
Mishra RR, Chaudhary JK, Rath PC. 2012. Cell cycle arrest and apoptosis by expression of a novel TPIP (TPIP-C2) cDNA encoding a C2-domain in HEK-293 cells. Mol. Biol. Rep. 39:7389-402
-
(2012)
Mol. Biol. Rep
, vol.39
, pp. 7389-7402
-
-
Mishra, R.R.1
Chaudhary, J.K.2
Rath, P.C.3
-
45
-
-
21744438625
-
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor
-
Murata Y, Iwasaki H, Sasaki M, Inaba K, Okamura Y. 2005. Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 435:1239-43
-
(2005)
Nature
, vol.435
, pp. 1239-1243
-
-
Murata, Y.1
Iwasaki, H.2
Sasaki, M.3
Inaba, K.4
Okamura, Y.5
-
46
-
-
34548725637
-
Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2
-
Murata Y, Okamura Y. 2007. Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2. J. Physiol. 583:875-89
-
(2007)
J. Physiol
, vol.583
, pp. 875-889
-
-
Murata, Y.1
Okamura, Y.2
-
47
-
-
45849122833
-
A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate
-
Iwasaki H, Murata Y, Kim Y, Hossain MI, Worby CA, et al. 2008. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc. Natl. Acad. Sci. USA 105:7970-75
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7970-7975
-
-
Iwasaki, H.1
Murata, Y.2
Kim, Y.3
Hossain, M.I.4
Worby, C.A.5
-
48
-
-
79955069961
-
Voltage-sensing phosphatase: Its molecular relationship with PTEN
-
Okamura Y, Dixon JE. 2011. Voltage-sensing phosphatase: its molecular relationship with PTEN. Physiology 26:6-13
-
(2011)
Physiology
, vol.26
, pp. 6-13
-
-
Okamura, Y.1
Dixon, J.E.2
-
49
-
-
77955445443
-
Self-organization of the phosphatidylinositol lipids signaling system for
-
random cell migration
-
Arai Y, Shibata T, Matsuoka S, Sato MJ, Yanagida T, Ueda M. 2010. Self-organization of the phosphatidylinositol lipids signaling system for random cell migration. Proc. Natl. Acad. Sci. USA 107:12399-404
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12399-12404
-
-
Arai, Y.1
Shibata, T.2
Matsuoka, S.3
Sato, M.J.4
Yanagida, T.5
Ueda, M.6
-
50
-
-
0037205265
-
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
-
Funamoto S, Meili R, Lee S, Parry L, Firtel RA. 2002. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109:611-23
-
(2002)
Cell
, vol.109
, pp. 611-623
-
-
Funamoto, S.1
Meili, R.2
Lee, S.3
Parry, L.4
Firtel, R.A.5
-
51
-
-
79951828073
-
Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN
-
Tang M, Iijima M, Kamimura Y, Chen L, Long Y, Devreotes P. 2011. Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN. Mol. Biol. Cell 22:437-47
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 437-447
-
-
Tang, M.1
Iijima, M.2
Kamimura, Y.3
Chen, L.4
Long, Y.5
Devreotes, P.6
-
52
-
-
34548258389
-
PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis
-
Wessels D, Lusche DF, Kuhl S, Heid P, Soll DR. 2007. PTEN plays a role in the suppression of lateral pseudopod formation during Dictyostelium motility and chemotaxis. J. Cell Sci. 120:2517-31
-
(2007)
J. Cell Sci
, vol.120
, pp. 2517-2531
-
-
Wessels, D.1
Lusche, D.F.2
Kuhl, S.3
Heid, P.4
Soll, D.R.5
-
53
-
-
0042354714
-
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
-
Xu J, Wang F, Van Keymeulen A,Herzmark P, Straight A, et al. 2003. Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 114:201-14
-
(2003)
Cell
, vol.114
, pp. 201-214
-
-
Xu, J.1
Wang, F.2
Van Keymeulen, A.3
Herzmark, P.4
Straight, A.5
-
54
-
-
0029978202
-
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase
-
Damen JE, Liu L, Rosten P, Humphries RK, Jefferson AB, et al. 1996. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase. Proc. Natl. Acad. Sci. USA 93:1689-93
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1689-1693
-
-
Damen, J.E.1
Liu, L.2
Rosten, P.3
Humphries, R.K.4
Jefferson, A.B.5
-
55
-
-
84859417595
-
Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion
-
Mondal S, Subramanian KK, Sakai J, Bajrami B, Luo HR. 2012. Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion. Mol. Biol. Cell 23:1219-30
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1219-1230
-
-
Mondal, S.1
Subramanian, K.K.2
Sakai, J.3
Bajrami, B.4
Luo, H.R.5
-
56
-
-
45549093769
-
PTEN functions to prioritize" chemotactic cues and prevent "distraction" in migrating neutrophils
-
Heit B, Robbins SM, Downey CM, Guan Z, Colarusso P, et al. 2008. PTEN functions to "prioritize" chemotactic cues and prevent "distraction" in migrating neutrophils. Nat. Immunol. 9:743-52
-
(2008)
Nat. Immunol
, vol.9
, pp. 743-752
-
-
Heit, B.1
Robbins, S.M.2
Downey, C.M.3
Guan, Z.4
Colarusso, P.5
-
57
-
-
66549115702
-
Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-Associated pneumonia
-
Li Y, Jia Y, Pichavant M, Loison F, Sarraj B, et al. 2009. Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-Associated pneumonia. Blood 113:4930-41
-
(2009)
Blood
, vol.113
, pp. 4930-4941
-
-
Li, Y.1
Jia, Y.2
Pichavant, M.3
Loison, F.4
Sarraj, B.5
-
58
-
-
77956211255
-
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia
-
Schabbauer G, Matt U, Günzl P, Warszawska J, Furtner T, et al. 2010. Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia. J. Immunol. 185:468-76
-
(2010)
J. Immunol
, vol.185
, pp. 468-476
-
-
Schabbauer, G.1
Matt, U.2
Günzl, P.3
Warszawska, J.4
Furtner, T.5
-
59
-
-
34247360789
-
Tumor suppressor PTEN is a physiologic suppressor of chemoattractant- mediated neutrophil functions
-
Subramanian KK, Jia Y, Zhu D, Simms BT, Jo H, et al. 2007. Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions. Blood 109:4028-37
-
(2007)
Blood
, vol.109
, pp. 4028-4037
-
-
Subramanian, K.K.1
Jia, Y.2
Zhu, D.3
Simms, B.T.4
Jo, H.5
-
60
-
-
0037428084
-
Tube morphogenesis: Making and shaping biological tubes
-
Lubarsky B, KrasnowMA. 2003. Tube morphogenesis: making and shaping biological tubes. Cell 112:19-28
-
(2003)
Cell
, vol.112
, pp. 19-28
-
-
Lubarsky, B.1
Krasnow, M.A.2
-
61
-
-
33748199154
-
Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells
-
Gassama-Diagne A, Yu W, ter BeestM,Martin-Belmonte F, Kierbel A, et al. 2006. Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nat. Cell Biol. 8:963-70
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 963-970
-
-
Gassama-Diagne, A.1
Yu, W.2
Ter Beest, M.3
Martin-Belmonte, F.4
Kierbel, A.5
-
62
-
-
33846270032
-
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42
-
Martin-Belmonte F, Gassama A, Datta A, Yu W, Rescher U, et al. 2007. PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. Cell 128:383-97
-
(2007)
Cell
, vol.128
, pp. 383-397
-
-
Martin-Belmonte, F.1
Gassama, A.2
Datta, A.3
Yu, W.4
Rescher, U.5
-
63
-
-
72849130207
-
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
-
Song LB, Li J, Liao WT, Feng Y, Yu CP, et al. 2009. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. J. Clin. Investig. 119:3626-36
-
(2009)
J. Clin. Investig
, vol.119
, pp. 3626-3636
-
-
Song, L.B.1
Li, J.2
Liao, W.T.3
Feng, Y.4
Yu, C.P.5
-
64
-
-
0032238299
-
The C elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
-
Ogg S, Ruvkun G. 1998. The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Mol. Cell 2:887-93
-
(1998)
Mol. Cell
, vol.2
, pp. 887-893
-
-
Ogg, S.1
Ruvkun, G.2
-
65
-
-
0027771804
-
A C elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. 1993. A C. elegans mutant that lives twice as long as wild type. Nature 366:461-64
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
66
-
-
0033572644
-
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway
-
Goberdhan DC, Paricio N, Goodman EC, Mlodzik M, Wilson C. 1999. Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes Dev. 13:3244-58
-
(1999)
Genes Dev
, vol.13
, pp. 3244-3258
-
-
Goberdhan, D.C.1
Paricio, N.2
Goodman, E.C.3
Mlodzik, M.4
Wilson, C.5
-
67
-
-
0034657764
-
Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways
-
Gao X, Neufeld TP, Pan D. 2000. Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways. Dev. Biol. 221:404-18
-
(2000)
Dev. Biol
, vol.221
, pp. 404-418
-
-
Gao, X.1
Neufeld, T.P.2
Pan, D.3
-
68
-
-
0034680008
-
The conserved PI3-K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila
-
Scanga SE, Ruel L, Binari RC, Snow B, Stambolic V, et al. 2000. The conserved PI3-K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila. Oncogene 19:3971-77
-
(2000)
Oncogene
, vol.19
, pp. 3971-3977
-
-
Scanga, S.E.1
Ruel, L.2
Binari, R.C.3
Snow, B.4
Stambolic, V.5
-
70
-
-
0037072780
-
The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes
-
Berwick DC, Hers I, Heesom KJ, Moule SK, Tavare JM. 2002. The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes. J. Biol. Chem. 277:33895-900
-
(2002)
J. Biol. Chem
, vol.277
, pp. 33895-33900
-
-
Berwick, D.C.1
Hers, I.2
Heesom, K.J.3
Moule, S.K.4
Tavare, J.M.5
-
71
-
-
0030734345
-
Physiological role of Akt in insulinstimulated translocation of GLUT4 in transfected rat adipose cells
-
Cong LN, Chen H, Li Y, Zhou L, McGibbon MA, et al. 1997. Physiological role of Akt in insulinstimulated translocation of GLUT4 in transfected rat adipose cells. Mol. Endocrinol. 11:1881-90
-
(1997)
Mol. Endocrinol
, vol.11
, pp. 1881-1890
-
-
Cong, L.N.1
Chen, H.2
Li, Y.3
Zhou, L.4
McGibbon, M.A.5
-
72
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn AD, Summers SA, BirnbaumMJ, Roth RA. 1996. Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J. Biol. Chem. 271:31372-78
-
(1996)
J. Biol. Chem
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
74
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
Horie Y, Suzuki A, Kataoka E, Sasaki T, Hamada K, et al. 2004. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J. Clin. Investig. 113:1774-83
-
(2004)
J. Clin. Investig
, vol.113
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
-
75
-
-
10744222107
-
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]
-
Stiles B,Wang Y, Stahl A, Bassilian S, Lee WP, et al. 2004. Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc. Natl. Acad. Sci. USA 101:2082-87
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2082-2087
-
-
Stiles, B.1
Wang, Y.2
Stahl, A.3
Bassilian, S.4
Lee, W.P.5
-
76
-
-
51849096491
-
The roles of PTEN in development, physiology and tumorigenesis in mouse models: A tissue-by-tissue survey
-
Knobbe CB, Lapin V, Suzuki A, Mak TW. 2008. The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey. Oncogene 27:5398-415
-
(2008)
Oncogene
, vol.27
, pp. 5398-5415
-
-
Knobbe, C.B.1
Lapin, V.2
Suzuki, A.3
Mak, T.W.4
-
77
-
-
84859215796
-
Systemic elevation of PTEN induces a tumor-suppressive metabolic state
-
Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, et al. 2012. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell 149:49-62
-
(2012)
Cell
, vol.149
, pp. 49-62
-
-
Garcia-Cao, I.1
Song, M.S.2
Hobbs, R.M.3
Laurent, G.4
Giorgi, C.5
-
78
-
-
84858037735
-
Pten positively regulates brown adipose function energy expenditure and longevity
-
Ortega-Molina A, Efeyan A, Lopez-Guadamillas E, Munoz-Martin M, G?mez-Löpez G, et al. 2012. Pten positively regulates brown adipose function, energy expenditure, and longevity. CellMetab. 15:382-94
-
(2012)
CellMetab
, vol.15
, pp. 382-394
-
-
Ortega-Molina, A.1
Efeyan, A.2
Lopez-Guadamillas, E.3
Munoz-Martin, M.4
Gm̈ez-Löpez, G.5
-
79
-
-
52649107626
-
Cancer cell metabolism: Warburg and beyond
-
Hsu PP, Sabatini DM. 2008. Cancer cell metabolism: Warburg and beyond. Cell 134:703-07
-
(2008)
Cell
, vol.134
, pp. 703-707
-
-
Hsu, P.P.1
Sabatini, D.M.2
-
80
-
-
79251502952
-
ATP consumption promotes cancermetabolism
-
Israelsen WJ, VanderHeidenMG. 2010. ATP consumption promotes cancermetabolism. Cell 143:669-71
-
(2010)
Cell
, vol.143
, pp. 669-671
-
-
Israelsen, W.J.1
Vander Heiden, M.G.2
-
81
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg O. 1956. On respiratory impairment in cancer cells. Science 124:269-70
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
82
-
-
0030748651
-
Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades
-
Deprez J, Vertommen D, Alessi DR, Hue L, Rider MH. 1997. Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J. Biol. Chem. 272:17269-75
-
(1997)
J. Biol. Chem
, vol.272
, pp. 17269-17275
-
-
Deprez, J.1
Vertommen, D.2
Alessi, D.R.3
Hue, L.4
Rider, M.H.5
-
83
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
Gottlob K, Majewski N, Kennedy S, Kandel E, Robey RB, Hay N. 2001. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 15:1406-18
-
(2001)
Genes Dev
, vol.15
, pp. 1406-1418
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
Kandel, E.4
Robey, R.B.5
Hay, N.6
-
85
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar AJ, Wong WJ, Simon MC. 2010. Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 40:294-309
-
(2010)
Mol. Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
86
-
-
84859445000
-
Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy
-
Semenza GL. 2012. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol. Sci. 33:207-14
-
(2012)
Trends Pharmacol. Sci
, vol.33
, pp. 207-214
-
-
Semenza, G.L.1
-
87
-
-
77955483125
-
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
-
Düvel K, Yecies JL, Menon S, Raman P, Lipovsky AI, et al. 2010. Activation of a metabolic gene regulatory network downstream of mTOR complex 1. Mol. Cell 39:171-83
-
(2010)
Mol. Cell
, vol.39
, pp. 171-183
-
-
Düvel, K.1
Yecies, J.L.2
Menon, S.3
Raman, P.4
Lipovsky, A.I.5
-
88
-
-
0037023755
-
Signaling networks that link cell proliferation and cell fate
-
Sears RC, Nevins JR. 2002. Signaling networks that link cell proliferation and cell fate. J. Biol. Chem. 277:11617-20
-
(2002)
J. Biol. Chem
, vol.277
, pp. 11617-11620
-
-
Sears, R.C.1
Nevins, J.R.2
-
90
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL. 2002. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer 2:489-501
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
91
-
-
9244239811
-
G1 cell-cycle control and cancer
-
Massague J. 2004. G1 cell-cycle control and cancer. Nature 432:298-306
-
(2004)
Nature
, vol.432
, pp. 298-306
-
-
Massague, J.1
-
93
-
-
84855885803
-
Cell cycle regulation in hematopoietic stem cells
-
Pietras EM, Warr MR, Passegu? E. 2011. Cell cycle regulation in hematopoietic stem cells. J. Cell Biol. 195:709-20
-
(2011)
J. Cell Biol
, vol.195
, pp. 709-720
-
-
Pietras, E.M.1
Warr, M.R.2
Passegu, E.3
-
94
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz OH, Valdez R, Theisen BK, GuoW, Ferguson DO, et al. 2006. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441:475-82
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
-
95
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J, Grindley JC, Yin T, Jayasinghe S, He XC, et al. 2006. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441:518-22
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
-
96
-
-
84866064701
-
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression
-
Magee JA, Ikenoue T, Nakada D, Lee JY, Guan KL, Morrison SJ. 2012. Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression. Cell Stem Cell 11:415-28
-
(2012)
Cell Stem Cell
, vol.11
, pp. 415-428
-
-
Magee, J.A.1
Ikenoue, T.2
Nakada, D.3
Lee, J.Y.4
Guan, K.L.5
Morrison, S.J.6
-
97
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D,Weinberg RA. 2011. Hallmarks of cancer: the next generation. Cell 144:646-74
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
99
-
-
70350510924
-
Pten in stromal fibroblasts suppresses mammary epithelial tumours
-
Trimboli AJ, Cantemir-Stone CZ, Li F,Wallace JA, Merchant A, et al. 2009. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature 461:1084-91
-
(2009)
Nature
, vol.461
, pp. 1084-1091
-
-
Trimboli, A.J.1
Cantemir-Stone, C.Z.2
Li Fwallace, J.A.3
Merchant, A.4
-
100
-
-
84856464305
-
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
-
Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, et al. 2012. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat. Cell Biol. 14:159-67
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 159-167
-
-
Bronisz, A.1
Godlewski, J.2
Wallace, J.A.3
Merchant, A.S.4
Nowicki, M.O.5
-
101
-
-
0036545993
-
Oxidative processes in the brain and non-neuronal tissues as biomarkers of Alzheimer's disease
-
Gibson GE, Huang HM. 2002. Oxidative processes in the brain and non-neuronal tissues as biomarkers of Alzheimer's disease. Front. Biosci. 7:D1007-15
-
(2002)
Front. Biosci
, vol.7
-
-
Gibson, G.E.1
Huang, H.M.2
-
102
-
-
0034467058
-
Activation of synovial fibroblasts in rheumatoid arthritis: Lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
-
Pap T, Franz JK, Hummel KM, Jeisy E, Gay R, Gay S. 2000. Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction. Arthritis Res. 2:59-64
-
(2000)
Arthritis Res
, vol.2
, pp. 59-64
-
-
Pap, T.1
Franz, J.K.2
Hummel, K.M.3
Jeisy, E.4
Gay, R.5
Gay, S.6
-
103
-
-
30344485686
-
Negative regulation of myofibroblast differentiation by PTEN (phosphatase and tensin homolog deleted on chromosome 10
-
White ES, Atrasz RG, Hu B, Phan SH, Stambolic V, et al. 2006. Negative regulation of myofibroblast differentiation by PTEN (phosphatase and tensin homolog deleted on chromosome 10). Am. J. Respir. Crit. Care Med. 173:112-21
-
(2006)
Am. J. Respir. Crit. Care Med
, vol.173
, pp. 112-121
-
-
White, E.S.1
Atrasz, R.G.2
Hu, B.3
Phan, S.H.4
Stambolic, V.5
-
104
-
-
84880737776
-
A secreted PTEN phosphatase that enters cells to alter signaling and survival
-
Hopkins BD, Fine B, Steinbach N, Dendy M, Rapp Z, et al. 2013. A secreted PTEN phosphatase that enters cells to alter signaling and survival. Science 341:399-402
-
(2013)
Science
, vol.341
, pp. 399-402
-
-
Hopkins, B.D.1
Fine, B.2
Steinbach, N.3
Dendy, M.4
Rapp, Z.5
-
105
-
-
0025895051
-
Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an arginine-rich motif required for transactivation
-
Subramanian T, Govindarajan R, Chinnadurai G. 1991. Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an arginine-rich motif required for transactivation. EMBO J. 10:2311-18
-
(1991)
EMBO J
, vol.10
, pp. 2311-2318
-
-
Subramanian, T.1
Govindarajan, R.2
Chinnadurai, G.3
-
106
-
-
0036568378
-
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma
-
Whiteman DC, Zhou XP, Cummings MC, Pavey S, Hayward NK, Eng C. 2002. Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. Int. J. Cancer 99:63-67
-
(2002)
Int. J. Cancer
, vol.99
, pp. 63-67
-
-
Whiteman, D.C.1
Zhou, X.P.2
Cummings, M.C.3
Pavey, S.4
Hayward, N.K.5
Eng, C.6
-
107
-
-
0033843623
-
Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors
-
Gimm O, Perren A, Weng LP, Marsh DJ, Yeh JJ, et al. 2000. Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors. Am. J. Pathol. 156:1693-700
-
(2000)
Am. J. Pathol
, vol.156
, pp. 1693-1700
-
-
Gimm, O.1
Perren, A.2
Weng, L.P.3
Marsh, D.J.4
Yeh, J.J.5
-
108
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
Perren A, Weng LP, Boag AH, Ziebold U, Thakore K, et al. 1999. Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am. J. Pathol. 155:1253-60
-
(1999)
Am. J. Pathol
, vol.155
, pp. 1253-1260
-
-
Perren, A.1
Weng, L.P.2
Boag, A.H.3
Ziebold, U.4
Thakore, K.5
-
109
-
-
0037439684
-
Increased nuclear phosphatase and tensin homologue deleted on chromosome 10 is associated with G0-G1 in MCF-7 cells
-
Ginn-Pease ME, Eng C. 2003. Increased nuclear phosphatase and tensin homologue deleted on chromosome 10 is associated with G0-G1 in MCF-7 cells. Cancer Res. 63:282-86
-
(2003)
Cancer Res
, vol.63
, pp. 282-286
-
-
Ginn-Pease, M.E.1
Eng, C.2
-
110
-
-
43249083765
-
PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression
-
Chang CJ, Mulholland DJ, Valamehr B, Mosessian S, Sellers WR, Wu H. 2008. PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression. Mol. Cell. Biol. 28:3281-89
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 3281-3289
-
-
Chang, C.J.1
Mulholland, D.J.2
Valamehr, B.3
Mosessian, S.4
Sellers, W.R.5
Wu, H.6
-
111
-
-
78651482046
-
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
-
Song MS, Carracedo A, Salmena L, Song SJ, Egia A, et al. 2011. Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase- independent manner. Cell 144:187-99
-
(2011)
Cell
, vol.144
, pp. 187-199
-
-
Song, M.S.1
Carracedo, A.2
Salmena, L.3
Song, S.J.4
Egia, A.5
-
112
-
-
76449096769
-
The anaphase-promoting complex/cyclosome (APC/C): Cell-cycle-dependent and -independent functions
-
Manchado E, Eguren M, MalumbresM. 2010. The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions. Biochem. Soc. Trans. 38:65-71
-
(2010)
Biochem. Soc. Trans
, vol.38
, pp. 65-71
-
-
Manchado, E.1
Eguren, M.2
Malumbres, M.3
-
113
-
-
73849129220
-
The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression
-
Wäsch R, Robbins JA, Cross FR. 2010. The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression. Oncogene 29:1-10
-
(2010)
Oncogene
, vol.29
, pp. 1-10
-
-
Wäsch, R.1
Robbins, J.A.2
Cross, F.R.3
-
114
-
-
33845999615
-
Essential role for nuclearPTENinmaintaining chromosomal integrity
-
ShenWH, Balajee AS,Wang J,WuH,Eng C, et al. 2007. Essential role for nuclearPTENinmaintaining chromosomal integrity. Cell 128:157-70
-
(2007)
Cell
, vol.128
, pp. 157-170
-
-
Shen, W.H.1
Balajee, A.S.2
Wang, J.3
Wu, H.4
Eng, C.5
-
115
-
-
68049097111
-
Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair
-
Gupta A, Yang Q, Pandita RK, Hunt CR, Xiang T, et al. 2009. Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle 8:2198-210
-
(2009)
Cell Cycle
, vol.8
, pp. 2198-2210
-
-
Gupta, A.1
Yang, Q.2
Pandita, R.K.3
Hunt, C.R.4
Xiang, T.5
-
116
-
-
84862815940
-
PTEN in DNA damage repair
-
Ming M, He YY. 2012. PTEN in DNA damage repair. Cancer Lett. 319:125-29
-
(2012)
Cancer Lett
, vol.319
, pp. 125-129
-
-
Ming, M.1
He, Y.Y.2
-
118
-
-
27444445782
-
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3?
-
Al-Khouri AM, Ma Y, Togo SH, Williams S, Mustelin T. 2005. Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3?. J. Biol. Chem. 280:35195-202
-
(2005)
J. Biol. Chem
, vol.280
, pp. 35195-35202
-
-
Al-Khouri, A.M.1
Ma, Y.2
Togo, S.H.3
Williams, S.4
Mustelin, T.5
-
119
-
-
34547490078
-
PTEN is destabilized by phosphorylation on Thr366
-
Maccario H, Perera NM, Davidson L, Downes CP, Leslie NR. 2007. PTEN is destabilized by phosphorylation on Thr366. Biochem. J. 405:439-44
-
(2007)
Biochem. J
, vol.405
, pp. 439-444
-
-
Maccario, H.1
Perera, N.M.2
Davidson, L.3
Downes, C.P.4
Leslie, N.R.5
-
120
-
-
84881308659
-
PD-1 increases PTEN phosphatase activity while decreasing PTEN protein stability by inhibiting casein kinase 2
-
Patsoukis N, Li L, Sari D, Petkova V, Boussiotis VA. 2013. PD-1 increases PTEN phosphatase activity while decreasing PTEN protein stability by inhibiting casein kinase 2. Mol. Cell. Biol. 33:3091-98
-
(2013)
Mol. Cell. Biol
, vol.33
, pp. 3091-3098
-
-
Patsoukis, N.1
Li, L.2
Sari, D.3
Petkova, V.4
Boussiotis, V.A.5
-
121
-
-
0037174166
-
Direct identification ofPTENphosphorylation sites
-
Miller SJ, Lou DY, SeldinDC,LaneWS, Neel BG. 2002. Direct identification ofPTENphosphorylation sites. FEBS Lett. 528:145-53
-
(2002)
FEBS Lett
, vol.528
, pp. 145-153
-
-
Miller, S.J.1
Lou, D.Y.2
Seldin, D.C.3
Lane, W.S.4
Neel, B.G.5
-
122
-
-
0036644058
-
Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation
-
Birle D, Bottini N, Williams S, Huynh H, deBelle I, et al. 2002. Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation. J. Immunol. 169:286-91
-
(2002)
J. Immunol
, vol.169
, pp. 286-291
-
-
Birle, D.1
Bottini, N.2
Williams, S.3
Huynh, H.4
De Belle, I.5
-
124
-
-
14544282456
-
Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor
-
Okumura K, Zhao M, Depinho RA, Furnari FB, Cavenee WK. 2005. Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc. Natl. Acad. Sci. USA 102:2703-6
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2703-2706
-
-
Okumura, K.1
Zhao, M.2
Depinho, R.A.3
Furnari, F.B.4
Cavenee, W.K.5
-
125
-
-
20244379418
-
Regulation of PTEN by Rho small GTPases
-
Li Z, Dong X, Wang Z, LiuW, Deng N, et al. 2005. Regulation of PTEN by Rho small GTPases. Nat. Cell Biol. 7:399-404
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 399-404
-
-
Li, Z.1
Dong, X.2
Wang, Z.3
Liu, W.4
Deng, N.5
-
126
-
-
84880710673
-
Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress
-
Bassi C, Ho J, Srikumar T, Dowling RJ, Gorrini C, et al. 2013. Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress. Science 341:395-99
-
(2013)
Science
, vol.341
, pp. 395-399
-
-
Bassi, C.1
Ho, J.2
Srikumar, T.3
Dowling, R.J.4
Gorrini, C.5
-
127
-
-
33845991111
-
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
-
Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, et al. 2007. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell 128:129-39
-
(2007)
Cell
, vol.128
, pp. 129-139
-
-
Wang, X.1
Trotman, L.C.2
Koppie, T.3
Alimonti, A.4
Chen, Z.5
-
128
-
-
63249130027
-
Rak functions as a tumor suppressor by regulating PTEN protein stability and function
-
Yim EK, Peng G, Dai H, Hu R, Li K, et al. 2009. Rak functions as a tumor suppressor by regulating PTEN protein stability and function. Cancer Cell 15:304-14
-
(2009)
Cancer Cell
, vol.15
, pp. 304-314
-
-
Yim, E.K.1
Peng, G.2
Dai, H.3
Hu, R.4
Li, K.5
-
129
-
-
45849087093
-
The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization
-
Fouladkou F, Landry T, Kawabe H, Neeb A, Lu C, et al. 2008. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proc. Natl. Acad. Sci. USA 105:8585-90
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 8585-8590
-
-
Fouladkou, F.1
Landry, T.2
Kawabe, H.3
Neeb, A.4
Lu, C.5
-
130
-
-
78149295998
-
Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas
-
Amodio N, Scrima M, Palaia L, Salman AN, Quintiero A, et al. 2010. Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas. Am. J. Pathol. 177:2622-34
-
(2010)
Am. J. Pathol
, vol.177
, pp. 2622-2634
-
-
Amodio, N.1
Scrima, M.2
Palaia, L.3
Salman, A.N.4
Quintiero, A.5
-
131
-
-
33845977965
-
Ubiquitination regulates PTEN nuclear import and tumor suppression
-
Trotman LC, Wang X, Alimonti A, Chen Z, Teruya-Feldstein J, et al. 2007. Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 128:141-56
-
(2007)
Cell
, vol.128
, pp. 141-156
-
-
Trotman, L.C.1
Wang, X.2
Alimonti, A.3
Chen, Z.4
Teruya-Feldstein, J.5
-
132
-
-
79957926724
-
WWP2 is an E3 ubiquitin ligase for PTEN
-
Maddika S, Kavela S, Rani N, Palicharla VR, Pokorny JL, et al. 2011. WWP2 is an E3 ubiquitin ligase for PTEN. Nat. Cell Biol. 13:728-33
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 728-733
-
-
Maddika, S.1
Kavela, S.2
Rani, N.3
Palicharla, V.R.4
Pokorny, J.L.5
-
133
-
-
70349495862
-
Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer
-
Dai Y, Qiao L, Chan KW, YangM, Ye J, et al. 2009. Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer. Mol. Cancer Ther. 8:2762-70
-
(2009)
Mol. Cancer Ther
, vol.8
, pp. 2762-2770
-
-
Dai, Y.1
Qiao, L.2
Chan, K.W.3
Yang, M.4
Ye, J.5
-
134
-
-
84863096004
-
Targeting X-linked inhibitor of apoptosis protein inhibits pancreatic cancer cell growth through p-Akt depletion
-
Jiang C, Yi XP, Shen H, Li YX. 2012. Targeting X-linked inhibitor of apoptosis protein inhibits pancreatic cancer cell growth through p-Akt depletion. World J. Gastroenterol. 18:2956-65
-
(2012)
World J. Gastroenterol
, vol.18
, pp. 2956-2965
-
-
Jiang, C.1
Yi, X.P.2
Shen, H.3
Li, Y.X.4
-
135
-
-
36749045012
-
XIAP is highly expressed in esophageal cancer and its downregulation by RNAi sensitizes esophageal carcinoma cell lines to chemotherapeutics
-
Zhang S,Ding F, Luo A, Chen A, Yu Z, et al. 2007. XIAP is highly expressed in esophageal cancer and its downregulation by RNAi sensitizes esophageal carcinoma cell lines to chemotherapeutics. Cancer Biol. Ther. 6:973-80
-
(2007)
Cancer Biol. Ther
, vol.6
, pp. 973-980
-
-
Zhang, S.1
Ding, F.2
Luo, A.3
Chen, A.4
Yu, Z.5
-
136
-
-
68949121012
-
X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization
-
Van Themsche C, Leblanc V, Parent S, Asselin E. 2009. X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization. J. Biol. Chem. 284:20462-66
-
(2009)
J. Biol. Chem
, vol.284
, pp. 20462-20466
-
-
Van Themsche, C.1
Leblanc, V.2
Parent, S.3
Asselin, E.4
-
137
-
-
53649106156
-
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
-
Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, et al. 2008. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature 455:813-17
-
(2008)
Nature
, vol.455
, pp. 813-817
-
-
Song, M.S.1
Salmena, L.2
Carracedo, A.3
Egia, A.4
Lo-Coco, F.5
-
138
-
-
36048935750
-
Protein expression and cellular localization in two prognostic subgroups of diffuse large B-cell lymphoma: Higher expression of ZAP70 and PKC-?II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN
-
Fridberg M, Servin A, Anagnostaki L, Linderoth J, Berglund M, et al. 2007. Protein expression and cellular localization in two prognostic subgroups of diffuse large B-cell lymphoma: higher expression of ZAP70 and PKC-?II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN. Leuk. Lymphoma 48:2221-32
-
(2007)
Leuk. Lymphoma
, vol.48
, pp. 2221-2232
-
-
Fridberg, M.1
Servin, A.2
Anagnostaki, L.3
Linderoth, J.4
Berglund, M.5
-
140
-
-
11144279346
-
The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway
-
Seo JH, Ahn Y, Lee SR, Yeo CY, Hur KC. 2005. The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway. Mol. Biol. Cell 16:348-57
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 348-357
-
-
Seo, J.H.1
Ahn, Y.2
Lee, S.R.3
Yeo, C.Y.4
Hur, K.C.5
-
141
-
-
9344259718
-
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
-
Kwon J, Lee SR, Yang KS, Ahn Y, Kim YJ, et al. 2004. Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors. Proc. Natl. Acad. Sci. USA 101:16419-24
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16419-16424
-
-
Kwon, J.1
Lee, S.R.2
Yang, K.S.3
Ahn, Y.4
Kim, Y.J.5
-
142
-
-
67349147914
-
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity
-
Cao J, Schulte J, Knight A, Leslie NR, Zagozdzon A, et al. 2009. Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. EMBO J. 28:1505-17
-
(2009)
EMBO J
, vol.28
, pp. 1505-1517
-
-
Cao, J.1
Schulte, J.2
Knight, A.3
Leslie, N.R.4
Zagozdzon, A.5
-
143
-
-
73949097658
-
Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN
-
Kim YC, Kitaura H, Taira T, Iguchi-Ariga SM, Ariga H. 2009. Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. Int. J. Oncol. 35:1331-41
-
(2009)
Int. J. Oncol
, vol.35
, pp. 1331-1341
-
-
Kim, Y.C.1
Kitaura, H.2
Taira, T.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
144
-
-
33748754795
-
PCAF modulates PTEN activity
-
Okumura K,MendozaM, Bachoo RM,DePinho RA, Cavenee WK, Furnari FB. 2006. PCAF modulates PTEN activity. J. Biol. Chem. 281:26562-68
-
(2006)
J. Biol. Chem
, vol.281
, pp. 26562-26568
-
-
Okumura, K.1
Mendoza, M.2
Bachoo, R.M.3
Depinho, R.A.4
Cavenee, W.K.5
Furnari, F.B.6
-
145
-
-
52049102233
-
PTEN acetylation modulates its interaction with PDZ domain
-
Ikenoue T, Inoki K, Zhao B, Guan KL. 2008. PTEN acetylation modulates its interaction with PDZ domain. Cancer Res. 68:6908-12
-
(2008)
Cancer Res
, vol.68
, pp. 6908-6912
-
-
Ikenoue, T.1
Inoki, K.2
Zhao, B.3
Guan, K.L.4
-
146
-
-
84865429543
-
SIRT1 promotes proliferation and inhibits apoptosis of human malignant glioma cell lines
-
Qu Y, Zhang J,Wu S, Li B, Liu S, Cheng J. 2012. SIRT1 promotes proliferation and inhibits apoptosis of human malignant glioma cell lines. Neurosci. Lett. 525:168-72
-
(2012)
Neurosci. Lett
, vol.525
, pp. 168-172
-
-
Qu, Y.1
Zhang Jwu, S.2
Li, B.3
Liu, S.4
Cheng, J.5
-
147
-
-
84863336040
-
SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane
-
Huang J, Yan J, Zhang J, Zhu S, Wang Y, et al. 2012. SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nat. Commun. 3:911
-
(2012)
Nat. Commun
, vol.3
, pp. 911
-
-
Huang, J.1
Yan, J.2
Zhang, J.3
Zhu, S.4
Wang, Y.5
-
148
-
-
84867195016
-
Regulation of the tumor suppressor PTEN by SUMO
-
González-Santamar J, Campagna M, Ortega-Molina A,Marcos-Villar L, de la Cruz-Herrera CF, et al. 2012. Regulation of the tumor suppressor PTEN by SUMO. Cell Death Dis. 3:e393
-
(2012)
Cell Death Dis
, vol.3
-
-
González-Santamar, J.1
Campagna, M.2
Ortega-Molina, A.3
Marcos-Villar, L.4
De La Cruz-Herrera, C.F.5
-
149
-
-
33644504867
-
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling
-
Takahashi Y, Morales FC, Kreimann EL, Georgescu MM. 2006. PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling. EMBO J. 25:910-20
-
(2006)
EMBO J
, vol.25
, pp. 910-920
-
-
Takahashi, Y.1
Morales, F.C.2
Kreimann, E.L.3
Georgescu, M.M.4
-
150
-
-
84858003974
-
Pten, nherf1 and phlpp form a tumor suppressor network that is disabled in glioblastoma
-
Molina JR, AgarwalNK, Morales FC, Hayashi Y, AldapeKD, et al. 2012. PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma. Oncogene 31:1264-74
-
(2012)
Oncogene
, vol.31
, pp. 1264-1274
-
-
Molina, J.R.1
Agarwal, N.K.2
Morales, F.C.3
Aldapekd, H.Y.4
-
151
-
-
84872825786
-
Suppression of survival signalling pathways by the phosphatase PHLPP
-
O'Neill AK, Niederst MJ, Newton AC. 2013. Suppression of survival signalling pathways by the phosphatase PHLPP. FEBS J. 280:572-83
-
(2013)
FEBS J
, vol.280
, pp. 572-583
-
-
O'neill, A.K.1
Niederst, M.J.2
Newton, A.C.3
-
152
-
-
0034867746
-
Co-downregulation of cell adhesion proteins ?-and ?-catenins, p120CTN, E-cadherin, and CD44 in prostatic adenocarcinomas
-
Kallakury BV, Sheehan CE, Ross JS. 2001. Co-downregulation of cell adhesion proteins ?-and ?-catenins, p120CTN, E-cadherin, and CD44 in prostatic adenocarcinomas. Hum. Pathol. 32:849-55
-
(2001)
Hum. Pathol
, vol.32
, pp. 849-855
-
-
Kallakury, B.V.1
Sheehan, C.E.2
Ross, J.S.3
-
153
-
-
0030601350
-
Common principles in cell adhesion
-
Ruoslahti E, Obrink B. 1996. Common principles in cell adhesion. Exp. Cell Res. 227:1-11
-
(1996)
Exp. Cell Res
, vol.227
, pp. 1-11
-
-
Ruoslahti, E.1
Obrink, B.2
-
154
-
-
14044261474
-
Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein ?-catenin with the scaffolding protein MAGI-2
-
Subauste MC, Nalbant P, Adamson ED, Hahn KM. 2005. Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein ?-catenin with the scaffolding protein MAGI-2. J. Biol. Chem. 280:5676-81
-
(2005)
J. Biol. Chem
, vol.280
, pp. 5676-5681
-
-
Subauste, M.C.1
Nalbant, P.2
Adamson, E.D.3
Hahn, K.M.4
-
155
-
-
11244250646
-
Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness
-
Kotelevets L, van Hengel J, Bruyneel E, Mareel M, van Roy F, Chastre E. 2005. Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness. FASEB J. 19:115-17
-
(2005)
FASEB J
, vol.19
, pp. 115-117
-
-
Kotelevets, L.1
Van Hengel, J.2
Bruyneel, E.3
Mareel, M.4
Van Roy, F.5
Chastre, E.6
-
156
-
-
0035945352
-
The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
-
Kotelevets L, van Hengel J, Bruyneel E, Mareel M, van Roy F, Chastre E. 2001. The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness. J. Cell Biol. 155:1129-35
-
(2001)
J. Cell Biol
, vol.155
, pp. 1129-1135
-
-
Kotelevets, L.1
Van Hengel, J.2
Bruyneel, E.3
Mareel, M.4
Van Roy, F.5
Chastre, E.6
-
157
-
-
0033958869
-
Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding
-
Adey NB, Huang L, Ormonde PA, Baumgard ML, Pero R, et al. 2000. Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding. Cancer Res. 60:35-37
-
(2000)
Cancer Res
, vol.60
, pp. 35-37
-
-
Adey, N.B.1
Huang, L.2
Ormonde, P.A.3
Baumgard, M.L.4
Pero, R.5
-
158
-
-
77953562076
-
Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination
-
Cotter L, Ozçlik M, Jacob C, Pereira JA, Locher V, et al. 2010. Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination. Science 328:1415-18
-
(2010)
Science
, vol.328
, pp. 1415-1418
-
-
Cotter, L.1
Ozçlik, M.2
Jacob, C.3
Pereira, J.A.4
Locher, V.5
-
159
-
-
80054912552
-
Deciphering tumor-suppressor signaling in flies: Genetic link between Scribble/ Dlg/Lgl and the Hippo pathways
-
EnomotoM, Igaki T. 2011. Deciphering tumor-suppressor signaling in flies: genetic link between Scribble/ Dlg/Lgl and the Hippo pathways. J. Genet. Genomics 38:461-70
-
(2011)
J. Genet. Genomics
, vol.38
, pp. 461-470
-
-
Enomoto, M.1
Igaki, T.2
-
160
-
-
0024344416
-
Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila
-
Woods DF, Bryant PJ. 1989. Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila. Dev. Biol. 134:222-35
-
(1989)
Dev. Biol
, vol.134
, pp. 222-235
-
-
Woods, D.F.1
Bryant, P.J.2
-
162
-
-
23844473290
-
Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-Associated serine/threonine kinases
-
Valiente M, Andr?s-Pons A, Gomar B, Torres J, Gil A, et al. 2005. Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-Associated serine/threonine kinases. J. Biol. Chem. 280:28936-43
-
(2005)
J. Biol. Chem
, vol.280
, pp. 28936-28943
-
-
Valiente, M.1
Andrés-Pons, A.2
Gomar, B.3
Torres, J.4
Gil, A.5
-
163
-
-
84865189134
-
Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN
-
Terrien E, Chaffotte A, Lafage M, Khan Z, PrehaudC, et al. 2012. Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN. Sci. Signal. 5:ra58
-
(2012)
Sci. Signal
, vol.5
-
-
Terrien, E.1
Chaffotte, A.2
Lafage, M.3
Prehaudc, K.Z.4
-
164
-
-
77955293704
-
Regulation of PTEN in neurons by myosin-based transport mechanisms
-
Kreis P, van Diepen MT, Eickholt BJ. 2010. Regulation of PTEN in neurons by myosin-based transport mechanisms. Adv. Enzyme Regul. 50:119-24
-
(2010)
Adv. Enzyme Regul
, vol.50
, pp. 119-124
-
-
Kreis, P.1
Van Diepen, M.T.2
Eickholt, B.J.3
-
165
-
-
77955299644
-
Indirect mechanisms of carcinogenesis via downregulation of PTEN function
-
Leslie NR, Spinelli L, Tibarewal P, Zilidis G, Weerasinghe N, et al. 2010. Indirect mechanisms of carcinogenesis via downregulation of PTEN function. Adv. Enzyme Regul. 50:112-18
-
(2010)
Adv. Enzyme Regul
, vol.50
, pp. 112-118
-
-
Leslie, N.R.1
Spinelli, L.2
Tibarewal, P.3
Zilidis, G.4
Weerasinghe, N.5
-
166
-
-
70349636462
-
MyosinV controls PTEN function and neuronal cell size
-
van Diepen MT, Parsons M, Downes CP, Leslie NR, Hindges R, Eickholt BJ. 2009. MyosinV controls PTEN function and neuronal cell size. Nat. Cell Biol. 11:1191-96
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 1191-1196
-
-
Van Diepen, M.T.1
Parsons, M.2
Downes, C.P.3
Leslie, N.R.4
Hindges, R.5
Eickholt, B.J.6
-
168
-
-
77950440345
-
Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase
-
Chagpar RB, Links PH, Pastor MC, Furber LA, Hawrysh AD, et al. 2010. Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 107:5471-76
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 5471-5476
-
-
Chagpar, R.B.1
Links, P.H.2
Pastor, M.C.3
Furber, L.A.4
Hawrysh, A.D.5
-
169
-
-
69949170092
-
Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a
-
Fine B, Hodakoski C, Koujak S, Su T, Saal LH, et al. 2009. Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. Science 325:1261-65
-
(2009)
Science
, vol.325
, pp. 1261-1265
-
-
Fine, B.1
Hodakoski, C.2
Koujak, S.3
Su, T.4
Saal, L.H.5
-
170
-
-
79955816876
-
Mannosidase 2C1 attenuates PTEN function in prostate cancer cells
-
He L, Fan C, Kapoor A, Ingram AJ, Rybak AP, et al. 2011. Mannosidase 2C1 attenuates PTEN function in prostate cancer cells. Nat. Commun. 2:307
-
(2011)
Nat. Commun
, vol.2
, pp. 307
-
-
He, L.1
Fan, C.2
Kapoor, A.3
Ingram, A.J.4
Rybak, A.P.5
-
171
-
-
77953213657
-
Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
-
He L, Ingram A, Rybak AP, Tang D. 2010. Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. J. Clin. Investig. 120:2094-108
-
(2010)
J. Clin. Investig
, vol.120
, pp. 2094-2108
-
-
He, L.1
Ingram, A.2
Rybak, A.P.3
Tang, D.4
-
172
-
-
0035199914
-
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
-
Virolle T, Adamson ED, Baron V, Birle D, Mercola D, et al. 2001. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat. Cell Biol. 3:1124-28
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 1124-1128
-
-
Virolle, T.1
Adamson, E.D.2
Baron, V.3
Birle, D.4
Mercola, D.5
-
173
-
-
0041450058
-
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
-
Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, et al. 2003. PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell 3:117-30
-
(2003)
Cancer Cell
, vol.3
, pp. 117-130
-
-
Freeman, D.J.1
Li, A.G.2
Wei, G.3
Li, H.H.4
Kertesz, N.5
-
174
-
-
33646368397
-
Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells
-
Shen YH, Zhang L, Gan Y, Wang X, Wang J, et al. 2006. Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells. J. Biol. Chem. 281:7727-36
-
(2006)
J. Biol. Chem
, vol.281
, pp. 7727-7736
-
-
Shen, Y.H.1
Zhang, L.2
Gan, Y.3
Wang, X.4
Wang, J.5
-
175
-
-
0035873953
-
Tumor suppressor and antiinflammatory actions of PPARγagonists are mediated via upregulation of PTEN
-
Patel L, Pass I, Coxon P, Downes CP, Smith SA, Macphee CH. 2001. Tumor suppressor and antiinflammatory actions of PPARγagonists are mediated via upregulation of PTEN. Curr. Biol. 11:764-68
-
(2001)
Curr. Biol
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
176
-
-
79953683693
-
Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins
-
Yoshimi A, Goyama S, Watanabe-Okochi N, Yoshiki Y, Nannya Y, et al. 2011. Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins. Blood 117:3617-28
-
(2011)
Blood
, vol.117
, pp. 3617-3628
-
-
Yoshimi, A.1
Goyama, S.2
Watanabe-Okochi, N.3
Yoshiki, Y.4
Nannya, Y.5
-
177
-
-
79251589918
-
Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer
-
Guo BH, Feng Y, Zhang R, Xu LH, Li MZ, et al. 2011. Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer. Mol. Cancer 10:10
-
(2011)
Mol. Cancer
, vol.10
, pp. 10
-
-
Guo, B.H.1
Feng, Y.2
Zhang, R.3
Xu, L.H.4
Li, M.Z.5
-
178
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R, Israel A. 1995. Signalling downstream of activated mammalian Notch. Nature 377:355-58
-
(1995)
Nature
, vol.377
, pp. 355-358
-
-
Jarriault, S.1
Brou, C.2
Logeat, F.3
Schroeter, E.H.4
Kopan, R.5
Israel, A.6
-
179
-
-
33846621883
-
CBF-1 (RBP-J?) binds to the PTEN promoter and regulates PTEN gene expression
-
Whelan JT, Forbes SL, Bertrand FE. 2007. CBF-1 (RBP-J?) binds to the PTEN promoter and regulates PTEN gene expression. Cell Cycle 6:80-84
-
(2007)
Cell Cycle
, vol.6
, pp. 80-84
-
-
Whelan, J.T.1
Forbes, S.L.2
Bertrand, F.E.3
-
180
-
-
67749135444
-
Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression
-
Whelan JT, Kellogg A, Shewchuk BM, Hewan-Lowe K, Bertrand FE. 2009. Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression. J. Cell. Biochem. 107:992-1001
-
(2009)
J. Cell. Biochem
, vol.107
, pp. 992-1001
-
-
Whelan, J.T.1
Kellogg, A.2
Shewchuk, B.M.3
Hewan-Lowe, K.4
Bertrand, F.E.5
-
181
-
-
33846232192
-
C-Jun promotes cellular survival by suppression of PTEN
-
Hettinger K, Vikhanskaya F, Poh MK, Lee MK, deBelle I, et al. 2007. c-Jun promotes cellular survival by suppression of PTEN. Cell Death Differ. 14:218-29
-
(2007)
Cell Death Differ
, vol.14
, pp. 218-229
-
-
Hettinger, K.1
Vikhanskaya, F.2
Poh, M.K.3
Lee, M.K.4
De Belle, I.5
-
182
-
-
38349030742
-
New insights into PTEN
-
Tamguney T, Stokoe D. 2007. New insights into PTEN. J. Cell Sci. 120:4071-79
-
(2007)
J. Cell Sci
, vol.120
, pp. 4071-4079
-
-
Tamguney, T.1
Stokoe, D.2
-
183
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo H, Ingolia NT, Weissman JS, Bartel DP. 2010. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466:835-40
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
184
-
-
84883310620
-
MicroRNA-17-92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways
-
Jin HY, Oda H, Lai M, Skalsky RL, Bethel K, et al. 2013. MicroRNA-17?92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways. EMBO J. 32:2377-91
-
(2013)
EMBO J
, vol.32
, pp. 2377-2391
-
-
Jin, H.Y.1
Oda, H.2
Lai, M.3
Skalsky, R.L.4
Bethel, K.5
-
185
-
-
78449293102
-
The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence
-
Hong L, Lai M, Chen M, Xie C, Liao R, et al. 2010. The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence. Cancer Res. 70:8547-57
-
(2010)
Cancer Res
, vol.70
, pp. 8547-8557
-
-
Hong, L.1
Lai, M.2
Chen, M.3
Xie, C.4
Liao, R.5
-
186
-
-
72849120988
-
MiR-19 is a key oncogenic component of mir-17-92
-
Olive V, Bennett MJ, Walker JC, Ma C, Jiang I, et al. 2009. miR-19 is a key oncogenic component of mir-17-92. Genes Dev. 23:2839-49
-
(2009)
Genes Dev
, vol.23
, pp. 2839-2849
-
-
Olive, V.1
Bennett, M.J.2
Walker, J.C.3
Ma, C.4
Jiang, I.5
-
187
-
-
84857079737
-
The microcosmos of cancer
-
Lujambio A, Lowe SW. 2012. The microcosmos of cancer. Nature 482:347-55
-
(2012)
Nature
, vol.482
, pp. 347-355
-
-
Lujambio, A.1
Lowe, S.W.2
-
188
-
-
84883478160
-
MiR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer
-
Cai J, Fang L, Huang Y, Li R, Yuan J, et al. 2013. miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Res. 73:5402-15
-
(2013)
Cancer Res
, vol.73
, pp. 5402-5415
-
-
Cai, J.1
Fang, L.2
Huang, Y.3
Li, R.4
Yuan, J.5
-
189
-
-
84876177255
-
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
-
Johnsson P, Ackley A, Vidarsdottir L, Lui WO, CorcoranM, et al. 2013. A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells. Nat. Struct. Mol. Biol. 20:440-46
-
(2013)
Nat. Struct. Mol. Biol
, vol.20
, pp. 440-446
-
-
Johnsson, P.1
Ackley, A.2
Vidarsdottir, L.3
Lui, W.O.4
Corcoran, M.5
-
190
-
-
77953957633
-
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
-
Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. 2010. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465:1033-38
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Salmena, L.2
Zhang, J.3
Carver, B.4
Haveman, W.J.5
Pandolfi, P.P.6
-
191
-
-
84865726286
-
The GENCODE pseudogene resource
-
Pei B, Sisu C, Frankish A, Howald C, Habegger L, et al. 2012. The GENCODE pseudogene resource. Genome Biol. 13:R51
-
(2012)
Genome Biol
, vol.13
-
-
Pei, B.1
Sisu, C.2
Frankish, A.3
Howald, C.4
Habegger, L.5
-
192
-
-
84866543760
-
Pseudogenes: Newly discovered players in human cancer
-
Poliseno L. 2012. Pseudogenes: newly discovered players in human cancer. Sci. Signal. 5:re5
-
(2012)
Sci. Signal
, vol.5
-
-
Poliseno, L.1
-
193
-
-
33644749218
-
PTEN promoter methylation in sporadic thyroid carcinomas
-
Alvarez-Nun∼ez F, Bussaglia E, Mauricio D, Ybarra J, Vilar M, et al. 2006. PTEN promoter methylation in sporadic thyroid carcinomas. Thyroid 16:17-23
-
(2006)
Thyroid
, vol.16
, pp. 17-23
-
-
Alvarez-Nunez, F.1
Bussaglia, E.2
Mauricio, D.3
Ybarra, J.4
Vilar, M.5
-
194
-
-
4143138570
-
Promoter methylation of the PTEN gene is a common molecular change in breast cancer
-
Garc JM, Silva J, Pen∼a C, Garcia V, Rodr?́uez R, et al. 2004. Promoter methylation of the PTEN gene is a common molecular change in breast cancer. Genes Chromosomes Cancer 41:117-24
-
(2004)
Genes Chromosomes Cancer
, vol.41
, pp. 117-124
-
-
Garc, J.M.1
Silva, J.2
Pena, C.3
Garcia, V.4
Rodŕuez, R.5
-
195
-
-
58149503967
-
PTEN promotermethylation andLOHof 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas
-
Ho CM, Lin MC,Huang SH,Huang CJ, Lai HC, et al. 2009. PTEN promotermethylation andLOHof 10q22-23 locus in PTEN expression of ovarian clear cell adenocarcinomas. Gynecol. Oncol. 112:307-13
-
(2009)
Gynecol. Oncol
, vol.112
, pp. 307-313
-
-
Ho, C.M.1
Lin, M.C.2
Huang, S.H.3
Huang, C.J.4
Lai, H.C.5
-
196
-
-
84867505054
-
PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome
-
Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, et al. 2012. PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome. Neuro-Oncology 14:1146-52
-
(2012)
Neuro-Oncology
, vol.14
, pp. 1146-1152
-
-
Mueller, S.1
Phillips, J.2
Onar-Thomas, A.3
Romero, E.4
Zheng, S.5
-
197
-
-
85027932610
-
Association of sporadic breast cancer with PTEN/MMAC1/ TEP1 promoter hypermethylation
-
Sadeq V, Isar N, Manoochehr T. 2011. Association of sporadic breast cancer with PTEN/MMAC1/ TEP1 promoter hypermethylation. Med. Oncol. 28:420-23
-
(2011)
Med. Oncol
, vol.28
, pp. 420-423
-
-
Sadeq, V.1
Isar, N.2
Manoochehr, T.3
-
198
-
-
34247277178
-
Epigenetic and genetic alterations of PTEN in hepatocellular carcinoma
-
Wang L, Wang WL, Zhang Y, Guo SP, Zhang J, Li QL. 2007. Epigenetic and genetic alterations of PTEN in hepatocellular carcinoma. Hepatol. Res. 37:389-96
-
(2007)
Hepatol. Res
, vol.37
, pp. 389-396
-
-
Wang, L.1
Wang, W.L.2
Zhang, Y.3
Guo, S.P.4
Zhang, J.5
Li, Q.L.6
-
199
-
-
79953038262
-
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
-
Hollander MC, Blumenthal GM, Dennis PA. 2011. PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat. Rev. Cancer 11:289-301
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 289-301
-
-
Hollander, M.C.1
Blumenthal, G.M.2
Dennis, P.A.3
-
200
-
-
78650503110
-
Germline epigenetic regulation ofKILLIN inCowden and Cowdenlike syndrome
-
Bennett KL,Mester J,Eng C. 2010. Germline epigenetic regulation ofKILLIN inCowden and Cowdenlike syndrome. J. Am. Med. Assoc. 304:2724-31
-
(2010)
J. Am. Med. Assoc
, vol.304
, pp. 2724-2731
-
-
Bennett, K.L.1
Mester, J.2
Eng, C.3
-
201
-
-
44449130834
-
Killin is a p53-regulated nuclear inhibitor of DNA synthesis
-
Cho YJ, Liang P. 2008. Killin is a p53-regulated nuclear inhibitor of DNA synthesis. Proc. Natl. Acad. Sci. USA 105:5396-401
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5396-5401
-
-
Cho, Y.J.1
Liang, P.2
-
202
-
-
84868193367
-
Analysis of KLLN as a high-penetrance breast cancer predisposition gene
-
Thompson ER, Gorringe KL, Choong DY, Eccles DM, Mitchell G, Campbell IG. 2012. Analysis of KLLN as a high-penetrance breast cancer predisposition gene. Breast Cancer Res. Treat. 134:543-47
-
(2012)
Breast Cancer Res. Treat
, vol.134
, pp. 543-547
-
-
Thompson, E.R.1
Gorringe, K.L.2
Choong, D.Y.3
Eccles, D.M.4
Mitchell, G.5
Campbell, I.G.6
-
203
-
-
79958071323
-
Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma
-
Bennett KL, Campbell R, Ganapathi S, Zhou M, Rini B, et al. 2011. Germline and somatic DNA methylation and epigenetic regulation of KILLIN in renal cell carcinoma. Genes Chromosomes Cancer 50:654-61
-
(2011)
Genes Chromosomes Cancer
, vol.50
, pp. 654-661
-
-
Bennett, K.L.1
Campbell, R.2
Ganapathi, S.3
Zhou, M.4
Rini, B.5
-
204
-
-
84868198811
-
PTENsignaling in autism spectrum disorders
-
Zhou J, Parada LF. 2012.PTENsignaling in autism spectrum disorders. Curr. Opin.Neurobiol. 22:873-79
-
(2012)
Curr. Opin.Neurobiol
, vol.22
, pp. 873-879
-
-
Zhou, J.1
Parada, L.F.2
-
206
-
-
4243110417
-
Pten dose dictates cancer progression in the prostate
-
Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, et al. 2003. Pten dose dictates cancer progression in the prostate. PLoS Biol. 1:E59
-
(2003)
PLoS Biol
, vol.1
-
-
Trotman, L.C.1
Niki, M.2
Dotan, Z.A.3
Koutcher, J.A.4
Di Cristofano, A.5
-
207
-
-
79551542888
-
PTEN level in tumor suppression:How much is too little?
-
Carracedo A, Alimonti A, Pandolfi PP. 2011. PTEN level in tumor suppression:How much is too little? Cancer Res. 71:629-33
-
(2011)
Cancer Res
, vol.71
, pp. 629-633
-
-
Carracedo, A.1
Alimonti, A.2
Pandolfi, P.P.3
|