Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association

Cell

Volumn 99, Issue 3, 1999, Pages 323-334

  Lee, Jie Oh ^a,b   Yang, Haijuan ^d   Georgescu, Maria Magdalena ^e   Cristofano, Antonio Di ^c   Maehama, Tomohiko ^f   Shi, Yigong ^g   Dixon, Jack E ^f   Pandolfi, Pier ^c   Pavletich, Nikola P ^a,b  

^a Cellular Biochemistry and Biophysics Program   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d Weill Cornell Graduate School of Biomedical Sciences   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^g PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PHOSPHATASE; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPID; POLYPEPTIDE; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MEMBRANE; PRIORITY JOURNAL; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; TUMOR SUPPRESSOR GENE;

EID: 0033615538     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81663-3     Document Type: Article

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