메뉴 건너뛰기




Volumn 16, Issue 4, 2005, Pages 183-189

FoxO proteins in insulin action and metabolism

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR FOXO;

EID: 18044381312     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2005.03.010     Document Type: Review
Times cited : (511)

References (73)
  • 1
    • 0027967521 scopus 로고
    • Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function
    • T.G. Unterman Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function Biochem. Biophys. Res. Commun. 203 1994 1835 1841
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1835-1841
    • Unterman, T.G.1
  • 2
    • 0025160127 scopus 로고
    • Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription
    • R.M. O'Brien Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription Science 249 1990 533 537
    • (1990) Science , vol.249 , pp. 533-537
    • O'Brien, R.M.1
  • 3
    • 0032513053 scopus 로고    scopus 로고
    • Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence
    • S.B. Cichy Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence J. Biol. Chem. 273 1998 6482 6487
    • (1998) J. Biol. Chem. , vol.273 , pp. 6482-6487
    • Cichy, S.B.1
  • 4
    • 0030659557 scopus 로고    scopus 로고
    • The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • S. Ogg The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans Nature 389 1997 994 999
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1
  • 5
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • K. Lin daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans Science 278 1997 1319 1322
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1
  • 6
    • 2942563805 scopus 로고    scopus 로고
    • Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
    • D.S. Hwangbo Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body Nature 429 2004 562 566
    • (2004) Nature , vol.429 , pp. 562-566
    • Hwangbo, D.S.1
  • 7
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
    • A. Brunet Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor Cell 96 1999 857 868
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1
  • 8
    • 0033522897 scopus 로고    scopus 로고
    • Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway
    • J. Nakae Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway J. Biol. Chem. 274 1999 15982 15985
    • (1999) J. Biol. Chem. , vol.274 , pp. 15982-15985
    • Nakae, J.1
  • 9
    • 0033560896 scopus 로고    scopus 로고
    • Direct control of the Forkhead transcription factor AFX by protein kinase B
    • G.J. Kops Direct control of the Forkhead transcription factor AFX by protein kinase B Nature 398 1999 630 634
    • (1999) Nature , vol.398 , pp. 630-634
    • Kops, G.J.1
  • 10
    • 0033546192 scopus 로고    scopus 로고
    • Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
    • S. Guo Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence J. Biol. Chem. 274 1999 17184 17192
    • (1999) J. Biol. Chem. , vol.274 , pp. 17184-17192
    • Guo, S.1
  • 11
    • 0034680839 scopus 로고    scopus 로고
    • Regulation of glucose-6-phosphatase gene expression by protein kinase Bα and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity
    • D. Schmoll Regulation of glucose-6-phosphatase gene expression by protein kinase Bα and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity J. Biol. Chem. 275 2000 36324 36333
    • (2000) J. Biol. Chem. , vol.275 , pp. 36324-36333
    • Schmoll, D.1
  • 12
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • J. Nakae The forkhead transcription factor FoxO1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression J. Clin. Invest. 108 2001 1359 1367
    • (2001) J. Clin. Invest. , vol.108 , pp. 1359-1367
    • Nakae, J.1
  • 13
    • 0035823515 scopus 로고    scopus 로고
    • Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences
    • D. Yeagley Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences J. Biol. Chem. 276 2001 33705 33710
    • (2001) J. Biol. Chem. , vol.276 , pp. 33705-33710
    • Yeagley, D.1
  • 14
    • 17344379513 scopus 로고    scopus 로고
    • Five years on the wings of fork head
    • E. Kaufmann, and W. Knochel Five years on the wings of fork head Mech. Dev. 57 1996 3 20
    • (1996) Mech. Dev. , vol.57 , pp. 3-20
    • Kaufmann, E.1    Knochel, W.2
  • 15
    • 0342614209 scopus 로고    scopus 로고
    • Unified nomenclature for the winged helix/forkhead transcription factors
    • K.H. Kaestner Unified nomenclature for the winged helix/forkhead transcription factors Genes Dev. 14 2000 142 146
    • (2000) Genes Dev. , vol.14 , pp. 142-146
    • Kaestner, K.H.1
  • 16
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • A. Brunet Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a) Mol. Cell. Biol. 21 2001 952 965
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 952-965
    • Brunet, A.1
  • 17
    • 0036566003 scopus 로고    scopus 로고
    • Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion
    • G. Rena Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion EMBO J. 21 2002 2263 2271
    • (2002) EMBO J. , vol.21 , pp. 2263-2271
    • Rena, G.1
  • 18
    • 0033595011 scopus 로고    scopus 로고
    • Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
    • W.H. Biggs Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 Proc. Natl. Acad. Sci. U. S. A. 96 1999 7421 7426
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 7421-7426
    • Biggs, W.H.1
  • 19
    • 0035868368 scopus 로고    scopus 로고
    • Roles of forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targeting
    • G. Rena Roles of forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targeting Biochem. J. 354 2001 605 612
    • (2001) Biochem. J. , vol.354 , pp. 605-612
    • Rena, G.1
  • 20
    • 0035340356 scopus 로고    scopus 로고
    • The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
    • Y.L. Woods The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site Biochem. J. 355 2001 597 607
    • (2001) Biochem. J. , vol.355 , pp. 597-607
    • Woods, Y.L.1
  • 21
    • 1642464560 scopus 로고    scopus 로고
    • Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: Characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms
    • X. Zhao Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms Biochem. J. 378 2004 839 849
    • (2004) Biochem. J. , vol.378 , pp. 839-849
    • Zhao, X.1
  • 22
    • 0346963162 scopus 로고    scopus 로고
    • Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding
    • T. Obsil Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding Biochemistry 42 2003 15264 15272
    • (2003) Biochemistry , vol.42 , pp. 15264-15272
    • Obsil, T.1
  • 23
    • 0035918148 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
    • C.M. Cahill Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways J. Biol. Chem. 276 2001 13402 13410
    • (2001) J. Biol. Chem. , vol.276 , pp. 13402-13410
    • Cahill, C.M.1
  • 24
    • 0037160050 scopus 로고    scopus 로고
    • Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding
    • X. Zhang Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding J. Biol. Chem. 277 2002 45276 45284
    • (2002) J. Biol. Chem. , vol.277 , pp. 45276-45284
    • Zhang, X.1
  • 25
    • 0141706357 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation of FKHR (FoxO1) targets to proteasomal degradation
    • H. Matsuzaki Insulin-induced phosphorylation of FKHR (FoxO1) targets to proteasomal degradation Proc. Natl. Acad. Sci. U. S. A. 100 2003 11285 11290
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 11285-11290
    • Matsuzaki, H.1
  • 26
    • 0141839103 scopus 로고    scopus 로고
    • Novel concepts in insulin regulation of hepatic gluconeogenesis
    • A. Barthel, and D. Schmoll Novel concepts in insulin regulation of hepatic gluconeogenesis Am. J. Physiol. Endocrinol. Metab. 285 2003 E685 E692
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285
    • Barthel, A.1    Schmoll, D.2
  • 27
    • 11144357466 scopus 로고    scopus 로고
    • IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
    • M.C. Hu IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a Cell 117 2004 225 237
    • (2004) Cell , vol.117 , pp. 225-237
    • Hu, M.C.1
  • 28
    • 8744224517 scopus 로고    scopus 로고
    • Inactivation of Rho/ROCK signalling is crucial for the nuclear accumulation of FKHR and myoblast fusion
    • T. Nishiyama Inactivation of Rho/ROCK signalling is crucial for the nuclear accumulation of FKHR and myoblast fusion J. Biol. Chem. 279 2004 47311 47319
    • (2004) J. Biol. Chem. , vol.279 , pp. 47311-47319
    • Nishiyama, T.1
  • 29
    • 11244320393 scopus 로고    scopus 로고
    • FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
    • M.A. Essers FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK EMBO J. 23 2004 4802 4812
    • (2004) EMBO J. , vol.23 , pp. 4802-4812
    • Essers, M.A.1
  • 30
    • 1342264308 scopus 로고    scopus 로고
    • Mammalian SIRT1 represses forkhead transcription factors
    • M.C. Motta Mammalian SIRT1 represses forkhead transcription factors Cell 116 2004 551 563
    • (2004) Cell , vol.116 , pp. 551-563
    • Motta, M.C.1
  • 31
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • A. Brunet Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2004 2011 2015
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1
  • 32
    • 3042750643 scopus 로고    scopus 로고
    • Silent information regulator 2 potentiates FoxO1-mediated transcription through its deacetylase activity
    • H. Daitoku Silent information regulator 2 potentiates FoxO1-mediated transcription through its deacetylase activity Proc. Natl. Acad. Sci. U. S. A. 101 2004 10042 10047
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 10042-10047
    • Daitoku, H.1
  • 33
    • 85047695408 scopus 로고    scopus 로고
    • Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells
    • D.L. Mahmud Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells Oncogene 21 2002 1556 1562
    • (2002) Oncogene , vol.21 , pp. 1556-1562
    • Mahmud, D.L.1
  • 34
    • 12944335299 scopus 로고    scopus 로고
    • DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
    • N. Nasrin DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells Proc. Natl. Acad. Sci. U. S. A. 97 2000 10412 10417
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 10412-10417
    • Nasrin, N.1
  • 35
    • 0038187621 scopus 로고    scopus 로고
    • Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
    • P. Puigserver Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction Nature 423 2003 550 555
    • (2003) Nature , vol.423 , pp. 550-555
    • Puigserver, P.1
  • 36
    • 0035855905 scopus 로고    scopus 로고
    • CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
    • S. Herzig CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nature 413 2001 179 183
    • (2001) Nature , vol.413 , pp. 179-183
    • Herzig, S.1
  • 37
    • 0037036407 scopus 로고    scopus 로고
    • Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein beta in differentiating human endometrial stromal cells
    • M. Christian Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein beta in differentiating human endometrial stromal cells J. Biol. Chem. 277 2002 20825 20832
    • (2002) J. Biol. Chem. , vol.277 , pp. 20825-20832
    • Christian, M.1
  • 38
    • 2542435874 scopus 로고    scopus 로고
    • Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and FoxO1
    • K. Yamagata Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and FoxO1 J. Biol. Chem. 279 2004 23158 23165
    • (2004) J. Biol. Chem. , vol.279 , pp. 23158-23165
    • Yamagata, K.1
  • 39
    • 0242580872 scopus 로고    scopus 로고
    • Convergence of peroxisome proliferator-activated receptor gamma and FoxO1 signaling pathways
    • P. Dowell Convergence of peroxisome proliferator-activated receptor gamma and FoxO1 signaling pathways J. Biol. Chem. 278 2003 45485 45491
    • (2003) J. Biol. Chem. , vol.278 , pp. 45485-45491
    • Dowell, P.1
  • 40
    • 0035823576 scopus 로고    scopus 로고
    • Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family
    • E.R. Schuur Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family J. Biol. Chem. 276 2001 33554 33560
    • (2001) J. Biol. Chem. , vol.276 , pp. 33554-33560
    • Schuur, E.R.1
  • 41
    • 0035958853 scopus 로고    scopus 로고
    • Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions
    • H.H. Zhao Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions J. Biol. Chem. 276 2001 27907 27912
    • (2001) J. Biol. Chem. , vol.276 , pp. 27907-27912
    • Zhao, H.H.1
  • 42
    • 0037216526 scopus 로고    scopus 로고
    • AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR
    • P. Li AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR Mol. Cell. Biol. 23 2003 104 118
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 104-118
    • Li, P.1
  • 43
    • 0037799266 scopus 로고    scopus 로고
    • Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism
    • M. Kortylewski Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism J. Biol. Chem. 278 2003 5242 5249
    • (2003) J. Biol. Chem. , vol.278 , pp. 5242-5249
    • Kortylewski, M.1
  • 44
    • 0038645860 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor
    • K. Hirota Hepatocyte nuclear factor-4 is a novel downstream target of insulin via FKHR as a signal-regulated transcriptional inhibitor J. Biol. Chem. 278 2003 13056 13060
    • (2003) J. Biol. Chem. , vol.278 , pp. 13056-13060
    • Hirota, K.1
  • 45
    • 1642332084 scopus 로고    scopus 로고
    • Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
    • J. Seoane Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation Cell 117 2004 211 223
    • (2004) Cell , vol.117 , pp. 211-223
    • Seoane, J.1
  • 46
    • 0037237279 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO1 regulates adipocyte differentiation
    • J. Nakae The forkhead transcription factor FoxO1 regulates adipocyte differentiation Dev. Cell 4 2003 119 129
    • (2003) Dev. Cell , vol.4 , pp. 119-129
    • Nakae, J.1
  • 47
    • 0036839685 scopus 로고    scopus 로고
    • Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
    • M. Schmidt Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D Mol. Cell. Biol. 22 2002 7842 7852
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7842-7852
    • Schmidt, M.1
  • 48
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • J. Gilley FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons J. Cell Biol. 162 2003 613 622
    • (2003) J. Cell Biol. , vol.162 , pp. 613-622
    • Gilley, J.1
  • 49
    • 0036629251 scopus 로고    scopus 로고
    • Cell cycle and death control: Long live Forkheads
    • B.M. Burgering, and G.J. Kops Cell cycle and death control: long live Forkheads Trends Biochem. Sci. 27 2002 352 360
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 352-360
    • Burgering, B.M.1    Kops, G.J.2
  • 50
    • 1542267804 scopus 로고    scopus 로고
    • Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
    • T. Hosaka Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification Proc. Natl. Acad. Sci. U. S. A. 101 2004 2975 2980
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 2975-2980
    • Hosaka, T.1
  • 51
    • 0036787607 scopus 로고    scopus 로고
    • Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor FoxO1
    • J. Nakae Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor FoxO1 Nat. Genet. 32 2002 245 253
    • (2002) Nat. Genet. , vol.32 , pp. 245-253
    • Nakae, J.1
  • 52
    • 0141727772 scopus 로고    scopus 로고
    • Inhibition of FoxO1 function is associated with improved fasting glycemia in diabetic mice
    • J. Altomonte Inhibition of FoxO1 function is associated with improved fasting glycemia in diabetic mice Am. J. Physiol. Endocrinol. Metab. 285 2003 E718 E728
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285
    • Altomonte, J.1
  • 53
    • 2942729543 scopus 로고    scopus 로고
    • Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein
    • X.Y. Zhou Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein Nat. Med. 10 2004 633 637
    • (2004) Nat. Med. , vol.10 , pp. 633-637
    • Zhou, X.Y.1
  • 54
    • 15244339047 scopus 로고    scopus 로고
    • Foxo1 mediates insulin action on apoC-III and triglyceride metabolism
    • J. Altomonte Foxo1 mediates insulin action on apoC-III and triglyceride metabolism J. Clin. Invest. 114 2004 1493 1503
    • (2004) J. Clin. Invest. , vol.114 , pp. 1493-1503
    • Altomonte, J.1
  • 55
    • 0036950665 scopus 로고    scopus 로고
    • The forkhead transcription factor FoxO1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
    • T. Kitamura, and W. Knochel The forkhead transcription factor FoxO1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth J. Clin. Invest. 110 2002 1839 1847
    • (2002) J. Clin. Invest. , vol.110 , pp. 1839-1847
    • Kitamura, T.1    Knochel, W.2
  • 56
    • 0042477748 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor-dependent myoblast differentiation by FoxO forkhead transcription factors
    • M.L. Hribal Regulation of insulin-like growth factor-dependent myoblast differentiation by FoxO forkhead transcription factors J. Cell Biol. 162 2003 535 541
    • (2003) J. Cell Biol. , vol.162 , pp. 535-541
    • Hribal, M.L.1
  • 57
    • 11144356337 scopus 로고    scopus 로고
    • FoxO transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • M. Sandri FoxO transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy Cell 117 2004 399 412
    • (2004) Cell , vol.117 , pp. 399-412
    • Sandri, M.1
  • 58
    • 2042425906 scopus 로고    scopus 로고
    • The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
    • T.N. Stitt The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors Mol. Cell 14 2004 395 403
    • (2004) Mol. Cell , vol.14 , pp. 395-403
    • Stitt, T.N.1
  • 59
    • 0142200472 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
    • T. Furuyama Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation Biochem. J. 375 2003 365 371
    • (2003) Biochem. J. , vol.375 , pp. 365-371
    • Furuyama, T.1
  • 60
    • 1842475551 scopus 로고    scopus 로고
    • Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors
    • G. Kwon Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors Diabetes 53 2004 899 910
    • (2004) Diabetes , vol.53 , pp. 899-910
    • Kwon, G.1
  • 61
    • 0037432191 scopus 로고    scopus 로고
    • A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle
    • Y. Kamei A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle FEBS Lett. 536 2003 232 236
    • (2003) FEBS Lett. , vol.536 , pp. 232-236
    • Kamei, Y.1
  • 62
    • 17144428529 scopus 로고    scopus 로고
    • FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and independent mechanisms
    • DOI: 10.1074/jbc.M413625200 (Epub ahead of print)
    • Bastie, C.C. et al. (2005) FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and independent mechanisms. J. Biol. Chem. DOI: 10.1074/jbc.M413625200 (Epub ahead of print)
    • (2005) J. Biol. Chem.
    • Bastie, C.C.1
  • 63
    • 3142701401 scopus 로고    scopus 로고
    • Insulin/FoxO1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity
    • A. Tsuchida Insulin/FoxO1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity J. Biol. Chem. 279 2004 30817 30822
    • (2004) J. Biol. Chem. , vol.279 , pp. 30817-30822
    • Tsuchida, A.1
  • 64
    • 0141481091 scopus 로고    scopus 로고
    • FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
    • F.M. Jacobs FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics J. Biol. Chem. 278 2003 35959 35967
    • (2003) J. Biol. Chem. , vol.278 , pp. 35959-35967
    • Jacobs, F.M.1
  • 65
    • 85030795842 scopus 로고    scopus 로고
    • Foxa2 regulates glucose and fatty acid metabolism in the liver during starvation and diabetes
    • (in press)
    • Wolfram, C. et al. Foxa2 regulates glucose and fatty acid metabolism in the liver during starvation and diabetes. Nature (in press)
    • Nature
    • Wolfram, C.1
  • 66
    • 3142742707 scopus 로고    scopus 로고
    • FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
    • A. van der Horst FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1) J. Biol. Chem. 279 2004 28873 28879
    • (2004) J. Biol. Chem. , vol.279 , pp. 28873-28879
    • Van Der Horst, A.1
  • 67
    • 0037018148 scopus 로고    scopus 로고
    • 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport
    • A. Brunet 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport J. Cell Biol. 156 2002 817 828
    • (2002) J. Cell Biol. , vol.156 , pp. 817-828
    • Brunet, A.1
  • 68
    • 0037449888 scopus 로고    scopus 로고
    • DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression
    • F. von Groote-Bidlingmaier DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression Biochem. Biophys. Res. Commun. 300 2003 764 769
    • (2003) Biochem. Biophys. Res. Commun. , vol.300 , pp. 764-769
    • Von Groote-Bidlingmaier, F.1
  • 69
    • 4444246000 scopus 로고    scopus 로고
    • Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
    • S. Kodama Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes Mol. Cell. Biol. 24 2004 7931 7940
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7931-7940
    • Kodama, S.1
  • 70
    • 0242298580 scopus 로고    scopus 로고
    • Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids
    • A. Kallwellis-Opara Characterization of cis-elements mediating the stimulation of glucose-6-phosphate transporter promoter activity by glucocorticoids Gene 320 2003 59 66
    • (2003) Gene , vol.320 , pp. 59-66
    • Kallwellis-Opara, A.1
  • 71
    • 0034730660 scopus 로고    scopus 로고
    • Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins
    • R.K. Hall Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins J. Biol. Chem. 275 2000 30169 30175
    • (2000) J. Biol. Chem. , vol.275 , pp. 30169-30175
    • Hall, R.K.1
  • 72
    • 0037342151 scopus 로고    scopus 로고
    • Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR
    • H. Daitoku Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR Diabetes 52 2003 642 649
    • (2003) Diabetes , vol.52 , pp. 642-649
    • Daitoku, H.1
  • 73
    • 0037103808 scopus 로고    scopus 로고
    • Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: The role of the forkhead transcription factor FKHRL1
    • A. Nadal Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl- CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1 Biochem. J. 366 2002 289 297
    • (2002) Biochem. J. , vol.366 , pp. 289-297
    • Nadal, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.