-
1
-
-
0033579163
-
Mutational spectra of PTEN/ MMAC1 gene: A tumor suppressor with lipid phosphatase activity
-
Ali IU, Schriml LM, Dean M. 1999. Mutational spectra of PTEN/ MMAC1 gene: a tumor suppressor with lipid phosphatase activity. J Natl Cancer Inst 91:1922-1932.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1922-1932
-
-
Ali, I.U.1
Schriml, L.M.2
Dean, M.3
-
2
-
-
0032500108
-
Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas
-
Bose S, Wang SI, Terry MB, Hibshoosh H, Parson R. 1998. Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas. Oncogene 9:123-127.
-
(1998)
Oncogene
, vol.9
, pp. 123-127
-
-
Bose, S.1
Wang, S.I.2
Terry, M.B.3
Hibshoosh, H.4
Parson, R.5
-
3
-
-
0036279974
-
Reduced expression of PTEN correlates with breast cancer progression
-
Bose S, Grane A, Hibshoosh H, Mansukhani H, Sandweis L, Parson R. 2002. Reduced expression of PTEN correlates with breast cancer progression. Hum Pathol 33:405-409.
-
(2002)
Hum Pathol
, vol.33
, pp. 405-409
-
-
Bose, S.1
Grane, A.2
Hibshoosh, H.3
Mansukhani, H.4
Sandweis, L.5
Parson, R.6
-
4
-
-
7144251865
-
A highly conserved processed PTEN pseudogene is located on chromosome band 9p21
-
Dahia PL, FitzGerald MG, Zhang X, Marsh DJ, Zheng Z, Pietsch T, von Deimling A, Hatuska FG, Haber DA, Eng C. 1998. A highly conserved processed PTEN pseudogene is located on chromosome band 9p21. Oncogene 16:2403-2406.
-
(1998)
Oncogene
, vol.16
, pp. 2403-2406
-
-
Dahia, P.L.1
FitzGerald, M.G.2
Zhang, X.3
Marsh, D.J.4
Zheng, Z.5
Pietsch, T.6
Von Deimling, A.7
Hatuska, F.G.8
Haber, D.A.9
Eng, C.10
-
6
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Domingez G, Bonilla F, Matias-Guiu X, Lerma E, Bussaglia E, Prat J, Harkes C, Repasky EA, Gabrielson E, Schutte M, Baylin SB, Herman JG. 2000. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 92:564-569.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Domingez, G.3
Bonilla, F.4
Matias-Guiu, X.5
Lerma, E.6
Bussaglia, E.7
Prat, J.8
Harkes, C.9
Repasky, E.A.10
Gabrielson, E.11
Schutte, M.12
Baylin, S.B.13
Herman, J.G.14
-
7
-
-
0033522145
-
Transcriptional analysis of the PTEN/MMAC1 pseudogene, psiPTEN
-
Fujii GH, Morimoto AM, Berson AE, Bolen JB. 1999. Transcriptional analysis of the PTEN/MMAC1 pseudogene, psiPTEN. Oncogene 18:1765-1769.
-
(1999)
Oncogene
, vol.18
, pp. 1765-1769
-
-
Fujii, G.H.1
Morimoto, A.M.2
Berson, A.E.3
Bolen, J.B.4
-
8
-
-
0032804162
-
Allelic loss of PTEN region (10q23) in breast carcinomas of poor pathophenotype
-
García JM, Silva JM, Dominguez G, Gonzalez R, Navarro A, Carretero L, Provencio M, España P, Bonilla F. 1999. Allelic loss of PTEN region (10q23) in breast carcinomas of poor pathophenotype. Breast Cancer Res Tr 57:237-243.
-
(1999)
Breast Cancer Res Tr
, vol.57
, pp. 237-243
-
-
García, J.M.1
Silva, J.M.2
Dominguez, G.3
Gonzalez, R.4
Navarro, A.5
Carretero, L.6
Provencio, M.7
España, P.8
Bonilla, F.9
-
9
-
-
0033984095
-
Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis
-
Guanti G, Resta N, Simone C, Cariola F, Demma I, Fiorente P, Gentile M. 2000. Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis. Hum Mol Genet 9:283-287.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 283-287
-
-
Guanti, G.1
Resta, N.2
Simone, C.3
Cariola, F.4
Demma, I.5
Fiorente, P.6
Gentile, M.7
-
10
-
-
0034014706
-
The expression profile for the tumour suppressor gene PTEN and associated polymorphic markers
-
Hamilton JA, Stewart LM, Ajayi L, Gray IC, Gray NE, Roberts KG, Watson GJ, Kaisary AV, Snary D. 2000. The expression profile for the tumour suppressor gene PTEN and associated polymorphic markers. Br J Cancer 82:1671-1676.
-
(2000)
Br J Cancer
, vol.82
, pp. 1671-1676
-
-
Hamilton, J.A.1
Stewart, L.M.2
Ajayi, L.3
Gray, I.C.4
Gray, N.E.5
Roberts, K.G.6
Watson, G.J.7
Kaisary, A.V.8
Snary, D.9
-
11
-
-
0042355204
-
Regulation of constitutive expression of mouse PTEN by the 5′-untranslated region
-
Han B, Dong Z, Liu Y, Chen Q, Hashimoto K, Zhang JT. 2003. Regulation of constitutive expression of mouse PTEN by the 5′-untranslated region. Oncogene 22:5325-5337.
-
(2003)
Oncogene
, vol.22
, pp. 5325-5337
-
-
Han, B.1
Dong, Z.2
Liu, Y.3
Chen, Q.4
Hashimoto, K.5
Zhang, J.T.6
-
12
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myöhänen S, Nelkin BD, Baylin SB. 1996. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 93:9821-9826.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myöhänen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
13
-
-
0036127525
-
Promoter methylation and silencing of PTEN in gastric carcinoma
-
Kang YH, Lee HS, Kim WH. 2002. Promoter methylation and silencing of PTEN in gastric carcinoma. Lab Invest 82:285-291.
-
(2002)
Lab Invest
, vol.82
, pp. 285-291
-
-
Kang, Y.H.1
Lee, H.S.2
Kim, W.H.3
-
14
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
-
Li DM, Sun H. 1997. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 57:2124-2129.
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
15
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. 1997. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer. Science 275: 1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
16
-
-
0031004088
-
Germ-line mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Li J, Dahia PLM, Wang SI, Zheng Z, Bose S, Call KM, Tsou HC, Peacocke M, Eng C, Parsons R. 1997. Germ-line mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16:64-67.
-
(1997)
Nat Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
17
-
-
0001182707
-
Cowden's disease: A possible new symptom complex with multiple system involvement
-
Lloyd KM, Dennis M. 1963. Cowden's disease: a possible new symptom complex with multiple system involvement. Ann Inter Med 58:136-142.
-
(1963)
Ann Inter Med
, vol.58
, pp. 136-142
-
-
Lloyd, K.M.1
Dennis, M.2
-
18
-
-
0033604468
-
The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells
-
Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M, Zinner R, Hung MC, Steck P, Stiminovitch K, Mills GB. 1999. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene 25:7034-7045.
-
(1999)
Oncogene
, vol.25
, pp. 7034-7045
-
-
Lu, Y.1
Lin, Y.Z.2
LaPushin, R.3
Cuevas, B.4
Fang, X.5
Yu, S.X.6
Davies, M.A.7
Khan, H.8
Furui, T.9
Mao, M.10
Zinner, R.11
Hung, M.C.12
Steck, P.13
Stiminovitch, K.14
Mills, G.B.15
-
19
-
-
0028888904
-
Cowden syndrome (multiple hamartoma syndrome)
-
Mallory SB. 1995. Cowden syndrome (multiple hamartoma syndrome). Dermatol Clin 13:27-31.
-
(1995)
Dermatol Clin
, vol.13
, pp. 27-31
-
-
Mallory, S.B.1
-
20
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
Marsh DJ, Dahia PLM, Zheng Z, Liaw D, Parsons R, Gorlin RJ, Eng C. 1997. Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat Genet 16:333-334.
-
(1997)
Nat Genet
, vol.16
, pp. 333-334
-
-
Marsh, D.J.1
Dahia, P.L.M.2
Zheng, Z.3
Liaw, D.4
Parsons, R.5
Gorlin, R.J.6
Eng, C.7
-
21
-
-
0030140025
-
Localization of the gene for Cowden disease to chromosome 10q22-23
-
Nelen MR, Padberg GW, Peeters EA, Lin AY, van der Helm B, Frants RR, Coulon V, Goldstein AM, van reen MM, Easton DF, Eeles RA, Hodgsen S, Mulvihill JJ, Murday VA, Mariman EC, Starink, TM, Ponder BA, Ropers HH, Kremer M, Longy M, Eng C. 1996. Localization of the gene for Cowden disease to chromosome 10q22-23. Nat Genet 13:114-116.
-
(1996)
Nat Genet
, vol.13
, pp. 114-116
-
-
Nelen, M.R.1
Padberg, G.W.2
Peeters, E.A.3
Lin, A.Y.4
Van Der Helm, B.5
Frants, R.R.6
Coulon, V.7
Goldstein, A.M.8
Van Reen, M.M.9
Easton, D.F.10
Eeles, R.A.11
Hodgsen, S.12
Mulvihill, J.J.13
Murday, V.A.14
Mariman, E.C.15
Starink, T.M.16
Ponder, B.A.17
Ropers, H.H.18
Kremer, M.19
Longy, M.20
Eng, C.21
more..
-
22
-
-
0032565070
-
Frequency of breast cancer attributable to BRCA1 in a population-based series of American women
-
Newman B, Mu H, Butler LM, Millikan RC, Moorman PG, King MC. 1998. Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. JAMA 279:915-921.
-
(1998)
JAMA
, vol.279
, pp. 915-921
-
-
Newman, B.1
Mu, H.2
Butler, L.M.3
Millikan, R.C.4
Moorman, P.G.5
King, M.C.6
-
23
-
-
0032006029
-
Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors
-
Okami K, Wu LU, Riggins G., Cairns P, Goggins M, Evron E, Halachmi N, Ahrendt SA, Reed AL, Hilgers W, Kern SE, Koch WM, Sidransky D, Jen J. 1998. Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors. Cancer Res 58:509-511.
-
(1998)
Cancer Res
, vol.58
, pp. 509-511
-
-
Okami, K.1
Wu, L.U.2
Riggins, G.3
Cairns, P.4
Goggins, M.5
Evron, E.6
Halachmi, N.7
Ahrendt, S.A.8
Reed, A.L.9
Hilgers, W.10
Kern, S.E.11
Koch, W.M.12
Sidransky, D.13
Jen, J.14
-
24
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
Perren A, Weng LP, Boag AH, Ziebold U, Thakore K, Dahia PL, Komminoth P, Lees JA, Mulligan LM, Mutter GL, Eng C. 1999. Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am J Pathol 155: 1253-1260.
-
(1999)
Am J Pathol
, vol.155
, pp. 1253-1260
-
-
Perren, A.1
Weng, L.P.2
Boag, A.H.3
Ziebold, U.4
Thakore, K.5
Dahia, P.L.6
Komminoth, P.7
Lees, J.A.8
Mulligan, L.M.9
Mutter, G.L.10
Eng, C.11
-
25
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
-
Rhei E, Kang L, Bogomolniy F, Federici MG, Borgen PI, Boyd J. 1997. Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res 57: 3657-3659.
-
(1997)
Cancer Res
, vol.57
, pp. 3657-3659
-
-
Rhei, E.1
Kang, L.2
Bogomolniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
26
-
-
0032212223
-
PTEN gene alterations in lymphoid neoplasm
-
Sakai A, Thieblemont C, Wellman A, Jaffe ES, Raffeld M. 1998. PTEN gene alterations in lymphoid neoplasm. Blood 92:3410-415.
-
(1998)
Blood
, vol.92
, pp. 3410-3415
-
-
Sakai, A.1
Thieblemont, C.2
Wellman, A.3
Jaffe, E.S.4
Raffeld, M.5
-
27
-
-
0035196043
-
PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma
-
Salvesen HB, MacDonald N, Ryan A, Jacobs IJ, Lynch ED, Akslen LA, Das S. 2001. PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma. Int J Cancer 91:22-26.
-
(2001)
Int J Cancer
, vol.91
, pp. 22-26
-
-
Salvesen, H.B.1
MacDonald, N.2
Ryan, A.3
Jacobs, I.J.4
Lynch, E.D.5
Akslen, L.A.6
Das, S.7
-
28
-
-
0036094196
-
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation
-
Soria JCH, Lee HY, Lee JI, Wang L, Issa JP, Kemp BL, Liu DD, Kurie JM, Mao L, Khuri FR. 2002. Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. Clin Cancer Res 8:1178-1184.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1178-1184
-
-
Soria, J.C.H.1
Lee, H.Y.2
Lee, J.I.3
Wang, L.4
Issa, J.P.5
Kemp, B.L.6
Liu, D.D.7
Kurie, J.M.8
Mao, L.9
Khuri, F.R.10
-
29
-
-
17144436629
-
Identification of a candidate tumour suppressor gene. MMAC1 at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Perhouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, Langford A, Baumbgard ML, Hattier T, Davis T, Frye Ch, Hu R, Swedlund B, Teng DH, Tavtigian SV. 1997. Identification of a candidate tumour suppressor gene, MMAC1 at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 15:356-362.
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Perhouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, A.7
Baumbgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, Ch.11
Hu, R.12
Swedlund, B.13
Teng, D.H.14
Tavtigian, S.V.15
-
30
-
-
0031916211
-
Sporadic breast cancer exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden Disease locus
-
Stingh B, Ittmann MM, Krolewski JJ. 1998. Sporadic breast cancer exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden Disease locus. Genes Chromosomes Cancer 21:166-171.
-
(1998)
Genes Chromosomes Cancer
, vol.21
, pp. 166-171
-
-
Stingh, B.1
Ittmann, M.M.2
Krolewski, J.J.3
-
31
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro H, Blazes MS, Wu R, Cho KR, Bose S, Wang SI, Li J, Parsons R, Ellenson LH. 1997. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 57:3935-3940.
-
(1997)
Cancer Res
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.6
Li, J.7
Parsons, R.8
Ellenson, L.H.9
-
32
-
-
14444269482
-
MAC1/PTEN mutations in primary tumor specimens and tumor cell lines
-
Teng DH, Hu R, Lin H, Davis T, Iliev D, Frye Ch, Swedlund B, Hansen KL, Vinson VL, Gupper KL, Ellis L, El-Naggar A, Frazier M, Jasser S, Langford LA, Lee J, Mills GB, Pershouse MA, Pollack RE, Tornos C, Troncoso P, Yung WKA, Fujii G, Berson A, Bookstein R, Bolen JB, Tavtigian SV, Steck PA. 1997. MAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res 57:5221-5225.
-
(1997)
Cancer Res
, vol.57
, pp. 5221-5225
-
-
Teng, D.H.1
Hu, R.2
Lin, H.3
Davis, T.4
Iliev, D.5
Frye, Ch.6
Swedlund, B.7
Hansen, K.L.8
Vinson, V.L.9
Gupper, K.L.10
Ellis, L.11
El-Naggar, A.12
Frazier, M.13
Jasser, S.14
Langford, L.A.15
Lee, J.16
Mills, G.B.17
Pershouse, M.A.18
Pollack, R.E.19
Tornos, C.20
Troncoso, P.21
Yung, W.K.A.22
Fujii, G.23
Berson, A.24
Bookstein, R.25
Bolen, J.B.26
Tavtigian, S.V.27
Steck, P.A.28
more..
-
33
-
-
0031827021
-
Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited Hamartoma syndromes
-
Wang ZJ, Taylor F, Churchman M, Norbury G, Tomlinson I. 1998. Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited Hamartoma syndromes. Am J Pathol 153:363-366.
-
(1998)
Am J Pathol
, vol.153
, pp. 363-366
-
-
Wang, Z.J.1
Taylor, F.2
Churchman, M.3
Norbury, G.4
Tomlinson, I.5
-
35
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G. 1995. Identification of the breast cancer susceptibility gene BRCA2. Nature 378:789-792.
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
Mangion, J.6
Collins, N.7
Gregory, S.8
Gumbs, C.9
Micklem, G.10
-
36
-
-
0034220889
-
Expression of PTEN and PTEN pseudogene in endometrial carcinoma
-
Yokoyama Y, Wan X, Shinohara A, Takahashi S, Takahashi Y, Niwa K, Tamaya T. 2000. Expression of PTEN and PTEN pseudogene in endometrial carcinoma. Int J Mol Med 6:47-50.
-
(2000)
Int J Mol Med
, vol.6
, pp. 47-50
-
-
Yokoyama, Y.1
Wan, X.2
Shinohara, A.3
Takahashi, S.4
Takahashi, Y.5
Niwa, K.6
Tamaya, T.7
-
37
-
-
0034618439
-
Detection of PTEN nonsense mutation and psiPTEN expression in central nervous system high-grade astrocytic tumors by a yeast-based stop codon assay
-
Zhang CL, Tada M, Kobayashi H, Nozaki M, Moriuchi T, Abe H. 2000. Detection of PTEN nonsense mutation and psiPTEN expression in central nervous system high-grade astrocytic tumors by a yeast-based stop codon assay. Oncogene 19:4346-4353.
-
(2000)
Oncogene
, vol.19
, pp. 4346-4353
-
-
Zhang, C.L.1
Tada, M.2
Kobayashi, H.3
Nozaki, M.4
Moriuchi, T.5
Abe, H.6
-
38
-
-
0036121266
-
Considerations when analyzing the methylation status of PTEN tumor suppressor gene
-
Zysman MA, Chapman WB, Bapa B. 2002. Considerations when analyzing the methylation status of PTEN tumor suppressor gene. Am J Pathol 160:795-1000.
-
(2002)
Am J Pathol
, vol.160
, pp. 795-1000
-
-
Zysman, M.A.1
Chapman, W.B.2
Bapa, B.3
|