메뉴 건너뛰기




Volumn 6, Issue 12, 2011, Pages

A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; TRANSMEMBRANE PHOSPHATASE WITH TENSIN HOMOLOGY AND PHOSPHATASE AND TENSIN HOMOLOGUE DELETED FROM HUMAN CHROMOSOME 10 HOMOLOGOUS INOSITOL LIPID PHOSPHATASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; TPIP (PROTEIN);

EID: 82555202982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028433     Document Type: Article
Times cited : (11)

References (44)
  • 1
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, et al. (1997) Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 15: 352-362.
    • (1997) Nat Genet , vol.15 , pp. 352-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3    Yung, W.K.4    Lin, H.5
  • 2
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor 1
    • Li DM, Sun H, (1997) TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor 1. Cancer Res 57: 2124-2129.
    • (1997) Cancer Res , vol.57 , pp. 2124-2129
    • Li, D.M.1    Sun, H.2
  • 3
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, Podsypanina K, Bose S, et al. (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275: 1943-1947.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Podsypanina, K.4    Bose, S.5
  • 4
    • 0031004088 scopus 로고    scopus 로고
    • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    • Liaw D, Marsh DJ, Li J, Dahia PL, Wang SI, et al. (1997) Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16: 64-67.
    • (1997) Nat Genet , vol.16 , pp. 64-67
    • Liaw, D.1    Marsh, D.J.2    Li, J.3    Dahia, P.L.4    Wang, S.I.5
  • 6
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of the PTEN tumor suppressor pathway
    • Sansal I, Sellers WR, (2004) The biology and clinical relevance of the PTEN tumor suppressor pathway. J Clin Oncol 22: 2954-2963.
    • (2004) J Clin Oncol , vol.22 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 7
    • 49149086504 scopus 로고    scopus 로고
    • PTEN: a default gate-keeping tumor suppressor with a versatile tail
    • Wang X, Jiang X, (2008) PTEN: a default gate-keeping tumor suppressor with a versatile tail. Cell Res 18: 807-816.
    • (2008) Cell Res , vol.18 , pp. 807-816
    • Wang, X.1    Jiang, X.2
  • 8
    • 77949452524 scopus 로고    scopus 로고
    • The PKB/AKT pathway in cancer
    • Carnero A, (2010) The PKB/AKT pathway in cancer. Curr Pharm Des 16: 34-44.
    • (2010) Curr Pharm Des , vol.16 , pp. 34-44
    • Carnero, A.1
  • 9
    • 0030837555 scopus 로고    scopus 로고
    • PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
    • Myers MP, Stolarov JP, Eng C, Li J, Wang SI, et al. (1997) PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A 94: 9052-9057.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9052-9057
    • Myers, M.P.1    Stolarov, J.P.2    Eng, C.3    Li, J.4    Wang, S.I.5
  • 10
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate
    • Maehama T, Dixon JE, (1998) The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate. J Biol Chem 273: 13375-13378.
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 11
    • 0033615538 scopus 로고    scopus 로고
    • Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association
    • Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, et al. (1999) Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99: 323-334.
    • (1999) Cell , vol.99 , pp. 323-334
    • Lee, J.O.1    Yang, H.2    Georgescu, M.M.3    Di Cristofano, A.4    Maehama, T.5
  • 12
    • 0034671221 scopus 로고    scopus 로고
    • Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor
    • Georgescu MM, Kirsch KH, Kaloudis P, Yang H, Pavletich NP, et al. (2000) Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor. Cancer Res 60: 7033-7038.
    • (2000) Cancer Res , vol.60 , pp. 7033-7038
    • Georgescu, M.M.1    Kirsch, K.H.2    Kaloudis, P.3    Yang, H.4    Pavletich, N.P.5
  • 13
    • 0033946740 scopus 로고    scopus 로고
    • Phosphorylation of the PTEN tail regulates protein stability and function
    • Vazquez F, Ramaswamy S, Nakamura N, Sellers WR, (2000) Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 20: 5010-8.
    • (2000) Mol Cell Biol , vol.20 , pp. 5010-5018
    • Vazquez, F.1    Ramaswamy, S.2    Nakamura, N.3    Sellers, W.R.4
  • 14
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: One gene, many syndromes
    • Eng C, (2003) PTEN: One gene, many syndromes. Hum Mutat 22: 183-198.
    • (2003) Hum Mutat , vol.22 , pp. 183-198
    • Eng, C.1
  • 15
    • 0038272084 scopus 로고    scopus 로고
    • Membrane-binding and activation mechanism of PTEN
    • Das S, Dixon JE, Cho W, (2003) Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A 100: 7491-7496.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7491-7496
    • Das, S.1    Dixon, J.E.2    Cho, W.3
  • 17
    • 34548154756 scopus 로고    scopus 로고
    • Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain
    • Odriozola L, Singh G, Hoang T, Chan AM, (2007) Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain. J Biol Chem 282: 23306-23315.
    • (2007) J Biol Chem , vol.282 , pp. 23306-23315
    • Odriozola, L.1    Singh, G.2    Hoang, T.3    Chan, A.M.4
  • 18
    • 1242284600 scopus 로고    scopus 로고
    • Regulation of cell migration by the C2 domain of the tumor suppressor PTEN
    • Raftopoulou M, Etienne-Manneville S, Self A, Nicholls S, Hall A, (2004) Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science 303: 1179-1181.
    • (2004) Science , vol.303 , pp. 1179-1181
    • Raftopoulou, M.1    Etienne-Manneville, S.2    Self, A.3    Nicholls, S.4    Hall, A.5
  • 19
    • 4143093730 scopus 로고    scopus 로고
    • Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity
    • Meuillet EJ, Mahadevan D, Berggren M, Coon A, Garth P, (2004) Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. Arch Biochem Biophys 429: 123-133.
    • (2004) Arch Biochem Biophys , vol.429 , pp. 123-133
    • Meuillet, E.J.1    Mahadevan, D.2    Berggren, M.3    Coon, A.4    Garth, P.5
  • 20
    • 26444610333 scopus 로고    scopus 로고
    • LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes
    • Mehenni H, Lin-Marq N, Buchet-Poyau K, Reymond A, Collart MA, et al. (2005) LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes. Hum Mol Genet 14: 2209-2219.
    • (2005) Hum Mol Genet , vol.14 , pp. 2209-2219
    • Mehenni, H.1    Lin-Marq, N.2    Buchet-Poyau, K.3    Reymond, A.4    Collart, M.A.5
  • 21
    • 0141919562 scopus 로고    scopus 로고
    • PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells
    • Zhou M, Gu L, Findley HW, Jiang R, Woods WG, (2003) PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells. Cancer Res 63: 6357-6362.
    • (2003) Cancer Res , vol.63 , pp. 6357-6362
    • Zhou, M.1    Gu, L.2    Findley, H.W.3    Jiang, R.4    Woods, W.G.5
  • 22
    • 31544454967 scopus 로고    scopus 로고
    • PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner
    • Tang Y, Eng C, (2006) PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner. Cancer Res 66: 736-742.
    • (2006) Cancer Res , vol.66 , pp. 736-742
    • Tang, Y.1    Eng, C.2
  • 23
    • 0032706145 scopus 로고    scopus 로고
    • A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y
    • Chen H, Rossier C, Morris MA, Scott HS, Gos A, et al. (1999) A testis-specific gene, TPTE, encodes a putative transmembrane tyrosine phosphatase and maps to the pericentromeric region of human chromosomes 21 and 13, and to chromosomes 15, 22, and Y. Hum Genet 105: 399-409.
    • (1999) Hum Genet , vol.105 , pp. 399-409
    • Chen, H.1    Rossier, C.2    Morris, M.A.3    Scott, H.S.4    Gos, A.5
  • 24
    • 0033822632 scopus 로고    scopus 로고
    • Genomic structure of a copy of the human TPTE gene which encompasses 87 kb on the short arm of chromosome 21
    • Guipponi M, Yaspo ML, Riesselman L, Chen H, Sario ADe, et al. (2000) Genomic structure of a copy of the human TPTE gene which encompasses 87 kb on the short arm of chromosome 21. Human Genet 107: 127-131.
    • (2000) Human Genet , vol.107 , pp. 127-131
    • Guipponi, M.1    Yaspo, M.L.2    Riesselman, L.3    Chen, H.4    Sario, A.D.5
  • 25
    • 0345059066 scopus 로고    scopus 로고
    • The TPTE gene family: cellular expression, subcellular localization and alternative splicing
    • Tapparel C, Reymond A, Girardet C, Guillou L, Lyle R, et al. (2003) The TPTE gene family: cellular expression, subcellular localization and alternative splicing. Gene 323: 189-199.
    • (2003) Gene , vol.323 , pp. 189-199
    • Tapparel, C.1    Reymond, A.2    Girardet, C.3    Guillou, L.4    Lyle, R.5
  • 26
    • 0035605844 scopus 로고    scopus 로고
    • TPIP: a novel phosphoinositide 3-phosphatase
    • Walker SM, Downes CP, Leslie NR, (2001) TPIP: a novel phosphoinositide 3-phosphatase. Biochem J 360: 277-283.
    • (2001) Biochem J , vol.360 , pp. 277-283
    • Walker, S.M.1    Downes, C.P.2    Leslie, N.R.3
  • 27
    • 82555181822 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human cDNAs by a simple repeat DNA probe: Identification of novel candidate genes
    • Ph.D. Thesis, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
    • Bajaj GD, (2002) Molecular cloning and characterization of human cDNAs by a simple repeat DNA probe: Identification of novel candidate genes. Ph.D. Thesis, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
    • (2002)
    • Bajaj, G.D.1
  • 29
    • 33144470077 scopus 로고    scopus 로고
    • Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer
    • Agrawal S, Eng C, (2006) Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer. Hum Mol Genet 15: 777-787.
    • (2006) Hum Mol Genet , vol.15 , pp. 777-787
    • Agrawal, S.1    Eng, C.2
  • 30
    • 0032715524 scopus 로고    scopus 로고
    • Association of some potential hormone response elements in human genes with Alu family repeats
    • Babich V, Aksenov N, Alexeenko V, Oei SL, Buchlow G, et al. (1999) Association of some potential hormone response elements in human genes with Alu family repeats. Gene 239: 341-349.
    • (1999) Gene , vol.239 , pp. 341-349
    • Babich, V.1    Aksenov, N.2    Alexeenko, V.3    Oei, S.L.4    Buchlow, G.5
  • 31
    • 0031985152 scopus 로고    scopus 로고
    • Apolipoprotein(a) gene enhancer resides within a LINE element
    • Yang Z, Boffelli D, Boonmark N, Schwartz K, Lawn R, (1998) Apolipoprotein(a) gene enhancer resides within a LINE element. J Biol Chem 273: 891-897.
    • (1998) J Biol Chem , vol.273 , pp. 891-897
    • Yang, Z.1    Boffelli, D.2    Boonmark, N.3    Schwartz, K.4    Lawn, R.5
  • 32
    • 0035877809 scopus 로고    scopus 로고
    • PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase
    • Wu Y, Dowbenko D, Pisabarro M, Dillard-Telm L, Koeppen H, et al. (2001) PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase. J Biol Chem 276: 21745-21753.
    • (2001) J Biol Chem , vol.276 , pp. 21745-21753
    • Wu, Y.1    Dowbenko, D.2    Pisabarro, M.3    Dillard-Telm, L.4    Koeppen, H.5
  • 33
    • 0032568662 scopus 로고    scopus 로고
    • C2 domain, structure and function of a universal Ca2+-binding domain
    • Rizo J, Südhof TC, (1998) C2 domain, structure and function of a universal Ca2+-binding domain. J Biol Chem 273: 15879-15882.
    • (1998) J Biol Chem , vol.273 , pp. 15879-15882
    • Rizo, J.1    Südhof, T.C.2
  • 34
    • 58849102128 scopus 로고    scopus 로고
    • A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN
    • Rahdar M, Inoue T, Meyer T, Zhang J, Vazquez F, et al. (2009) A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN. Proc Natl Acad Sci U S A 106: 480-485.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 480-485
    • Rahdar, M.1    Inoue, T.2    Meyer, T.3    Zhang, J.4    Vazquez, F.5
  • 35
    • 79952622680 scopus 로고    scopus 로고
    • PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation
    • Lee JJ, Kim BC, Park MJ, Lee YS, Kim YN, et al. (2011) PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation. Cell Death Differ 18: 666-677.
    • (2011) Cell Death Differ , vol.18 , pp. 666-677
    • Lee, J.J.1    Kim, B.C.2    Park, M.J.3    Lee, Y.S.4    Kim, Y.N.5
  • 36
    • 80054706894 scopus 로고    scopus 로고
    • Induction of apoptotic genes by a p73-PTEN complex in response to genotoxic stress
    • Lehman JA, Waning DL, Batuello CN, Cipriano R, Kadakia MP, et al. (2011) Induction of apoptotic genes by a p73-PTEN complex in response to genotoxic stress. J Biol Chem 286: 36631-36640.
    • (2011) J Biol Chem , vol.286 , pp. 36631-36640
    • Lehman, J.A.1    Waning, D.L.2    Batuello, C.N.3    Cipriano, R.4    Kadakia, M.P.5
  • 37
    • 0033229893 scopus 로고    scopus 로고
    • The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells
    • Maier D, Jones G, Li X, Schonthal AH, Gratzl O, et al. (1999) The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells. Cancer Res 59: 5479-5482.
    • (1999) Cancer Res , vol.59 , pp. 5479-5482
    • Maier, D.1    Jones, G.2    Li, X.3    Schonthal, A.H.4    Gratzl, O.5
  • 38
    • 4644285846 scopus 로고    scopus 로고
    • PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity
    • Gildea JJ, Herlevsen M, Harding MA, Gulding KM, Moskaluk CA, et al. (2004) PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity. Oncogene 23: 6788-6797.
    • (2004) Oncogene , vol.23 , pp. 6788-6797
    • Gildea, J.J.1    Herlevsen, M.2    Harding, M.A.3    Gulding, K.M.4    Moskaluk, C.A.5
  • 39
    • 33746990186 scopus 로고    scopus 로고
    • Mechanistic insights into maintenance of high p53 acetylation by PTEN
    • Li AG, Piluso LG, Cai X, Wei G, Sellers WR, et al. (2006) Mechanistic insights into maintenance of high p53 acetylation by PTEN. Mol Cell 23: 575-587.
    • (2006) Mol Cell , vol.23 , pp. 575-587
    • Li, A.G.1    Piluso, L.G.2    Cai, X.3    Wei, G.4    Sellers, W.R.5
  • 40
    • 77954374206 scopus 로고    scopus 로고
    • PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and -independent mechanisms in HepG2 cells
    • Tian T, Nan KJ, Wang SH, Liang X, Lu CX, et al. (2010) PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and-independent mechanisms in HepG2 cells. Carcinogenesis 31: 1211-1219.
    • (2010) Carcinogenesis , vol.31 , pp. 1211-1219
    • Tian, T.1    Nan, K.J.2    Wang, S.H.3    Liang, X.4    Lu, C.X.5
  • 41
    • 79951848196 scopus 로고    scopus 로고
    • Inhibition of U6 snRNA transcription by PTEN
    • Cabarcas S, Watabe K, Schramm L, (2010) Inhibition of U6 snRNA transcription by PTEN. Online J Biol Sci 10: 114-125.
    • (2010) Online J Biol Sci , vol.10 , pp. 114-125
    • Cabarcas, S.1    Watabe, K.2    Schramm, L.3
  • 42
    • 78549267766 scopus 로고    scopus 로고
    • the structural basis for membrane binding and pore formation by lymphocyte perforin
    • Law RH, Lukoyanova N, Voskoboinik I, Caradoc-Davies TT, Baran K, et al. (2010) the structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 468: 447-451.
    • (2010) Nature , vol.468 , pp. 447-451
    • Law, R.H.1    Lukoyanova, N.2    Voskoboinik, I.3    Caradoc-Davies, T.T.4    Baran, K.5
  • 43
    • 11144231721 scopus 로고    scopus 로고
    • A novel rat genomic simple repeat DNA with RNA-homology shows triplex (H-DNA)-like structure and tissue-specific RNA expression
    • Dey I, Rath PC, (2005) A novel rat genomic simple repeat DNA with RNA-homology shows triplex (H-DNA)-like structure and tissue-specific RNA expression. Biochem Biophys Res Commun 327: 276-286.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 276-286
    • Dey, I.1    Rath, P.C.2
  • 44
    • 0004136246 scopus 로고    scopus 로고
    • Molecular Cloning: A Laboratory Manual
    • 3rd ed. Cold Spring Harbor Laboratory Press, New York
    • Sambrook J, Russell DW, (2001) Molecular Cloning: A Laboratory Manual. 3rd ed. Cold Spring Harbor Laboratory Press, New York.
    • (2001)
    • Sambrook, J.1    Russell, D.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.