Pten dose dictates cancer progression in the prostate

PLoS Biology

Volumn 1, Issue 3, 2003, Pages

  Trotman, Lloyd C ^a   Niki, Masaru ^a   Dotan, Zohar A ^a   Koutcher, Jason A ^a   Di Cristofano, Antonio ^a   Xiao, Andrew ^b   Khoo, Alan S ^a   Roy Burman, Pradip ^c   Greenberg, Norman M ^d   Van Dyke, Terry ^b   Cordon Cardo, Carlos ^a   Pandolfi, Pier Paolo ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P27; TARGET OF RAPAMYCIN KINASE; TUMOR SUPPRESSOR PROTEIN; CDKN1B PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE; PTEN PROTEIN, MOUSE;

ALLELE; ARTICLE; CANCER GROWTH; CANCER INCIDENCE; CANCER INHIBITION; COMPARATIVE STUDY; DOSE RESPONSE; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE INACTIVATION; GENE MUTATION; HOMOLOGOUS RECOMBINATION; HUMAN; MOLECULAR GENETICS; PATHOPHYSIOLOGY; PROSTATE CARCINOMA; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR GENE; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CROSS BREEDING; DISEASE COURSE; EPITHELIUM; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC RECOMBINATION; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOUSE; MOUSE MUTANT; MUTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHYSIOLOGY; PROSTATE; PROSTATE TUMOR;

ALLELES; ANIMALS; CELLS, CULTURED; CROSSES, GENETIC; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DISEASE PROGRESSION; EPITHELIUM; FIBROBLASTS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, KNOCKOUT; MODELS, GENETIC; MUTATION; PROSTATE; PROSTATIC NEOPLASMS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECOMBINATION, GENETIC;

EID: 4243110417     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0000059     Document Type: Article

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