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Volumn 7, Issue 4, 2005, Pages 399-404

Regulation of PTEN by Rho small GTPases

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN CDC42; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 20244379418     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1236     Document Type: Article
Times cited : (409)

References (30)
  • 1
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano, A. & Pandolfi, R P. The multiple roles of PTEN in tumor suppression. Cell 100, 387-390 (2000).
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 2
    • 0034911881 scopus 로고    scopus 로고
    • Synthesis and function of 3-phosphorylated inositol lipids
    • Vanhaesebroeck, B. et al. Synthesis and function of 3-phosphorylated inositol lipids. Annu. Rev. Biochem. 70, 535-602 (2001).
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 535-602
    • Vanhaesebroeck, B.1
  • 3
    • 0142011466 scopus 로고    scopus 로고
    • PTEN: From pathology to biology
    • Sulis, M. L. & Parsons, R. PTEN: from pathology to biology. Trends Cell Biol. 13, 478-483 (2003).
    • (2003) Trends Cell Biol. , vol.13 , pp. 478-483
    • Sulis, M.L.1    Parsons, R.2
  • 4
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
    • Cantley, L. C. & Neel, B.G. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc. Natl Acad. Sci. USA 96, 4240-4245 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 5
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura, M. et al. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280, 1614-1617 (1998).
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1
  • 6
    • 0343183328 scopus 로고    scopus 로고
    • Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
    • Liliental, J. et al. Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases. Curr. Biol. 10, 401-404 (2000).
    • (2000) Curr. Biol. , vol.10 , pp. 401-404
    • Liliental, J.1
  • 7
    • 1242284600 scopus 로고    scopus 로고
    • Regulation of cell migration by the C2 domain of the tumor suppressor PTEN
    • Raftopoulou, M., Etienne-Manneville, S., Self, A., Nicholls, S. & Hall, A. Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science 303, 1179-1181 (2004).
    • (2004) Science , vol.303 , pp. 1179-1181
    • Raftopoulou, M.1    Etienne-Manneville, S.2    Self, A.3    Nicholls, S.4    Hall, A.5
  • 8
    • 0037205266 scopus 로고    scopus 로고
    • PI 3-kinases and PTEN: How opposites chemoattract
    • Comer, F. I. & Parent, C. A. PI 3-kinases and PTEN: how opposites chemoattract. Cell 109, 541-544 (2002).
    • (2002) Cell , vol.109 , pp. 541-544
    • Comer, F.I.1    Parent, C.A.2
  • 9
    • 0037743735 scopus 로고    scopus 로고
    • Eukaryotic chemotaxis: Distinctions between directional sensing and polarization
    • Devreotes, P. & Janetopoulos, C. Eukaryotic chemotaxis: distinctions between directional sensing and polarization. J. Biol. Chem. 278, 20445-20448 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 20445-20448
    • Devreotes, P.1    Janetopoulos, C.2
  • 10
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto, S., Meiii, R., Lee, S., Parry, L. & Firtel, R.A. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109, 611-623 (2002).
    • (2002) Cell , vol.109 , pp. 611-623
    • Funamoto, S.1    Meiii, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 11
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima, M. & Devreotes, P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109, 599-610 (2002).
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 12
    • 0041352963 scopus 로고    scopus 로고
    • Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42
    • Li, Z. et al. Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell 114, 215-227 (2003).
    • (2003) Cell , vol.114 , pp. 215-227
    • Li, Z.1
  • 13
    • 0033838716 scopus 로고    scopus 로고
    • Regulation of cell function by Rho family GTPases
    • Bokoch, G. M. Regulation of cell function by Rho family GTPases. Immunol. Res. 21, 139-148 (2000).
    • (2000) Immunol. Res. , vol.21 , pp. 139-148
    • Bokoch, G.M.1
  • 14
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. Rho GTPases and the actin cytoskeleton. Science 279, 509-514 (1998).
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 15
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. & Hall, A. Rho GTPases in cell biology. Nature 420, 629-635 (2002).
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 16
    • 0141533034 scopus 로고    scopus 로고
    • Roles of Rho-family GTPases in cell polarisation and directional migration
    • Fukata, M., Nakagawa, M. & Kaibuchi, K. Roles of Rho-family GTPases in cell polarisation and directional migration. Curr. Opin. Cell Biol. 15, 590-597 (2003).
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 590-597
    • Fukata, M.1    Nakagawa, M.2    Kaibuchi, K.3
  • 17
    • 0042354714 scopus 로고    scopus 로고
    • Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
    • Xu, J. et al. Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell 114, 201-214 (2003).
    • (2003) Cell , vol.114 , pp. 201-214
    • Xu, J.1
  • 18
    • 0033531955 scopus 로고    scopus 로고
    • Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases
    • Benard, V., Bohl, B. P. & Bokoch, G. M. Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases. J. Biol. Chem. 274, 13198-13204 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 13198-13204
    • Benard, V.1    Bohl, B.P.2    Bokoch, G.M.3
  • 19
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata, M. et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994 (1997).
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1
  • 20
    • 0029805324 scopus 로고    scopus 로고
    • Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
    • Lim, L., Manser, E., Leung, T. & Hall, C. Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways. Eur. J. Biochem. 242, 171-185 (1996).
    • (1996) Eur. J. Biochem. , vol.242 , pp. 171-185
    • Lim, L.1    Manser, E.2    Leung, T.3    Hall, C.4
  • 21
    • 0034715885 scopus 로고    scopus 로고
    • Regulation and functions of Rho-associated kinase
    • Amano, M., Fukata, Y. & Kaibuchi, K. Regulation and functions of Rho-associated kinase. Exp. Cell Res. 261, 44-51 (2000).
    • (2000) Exp. Cell Res. , vol.261 , pp. 44-51
    • Amano, M.1    Fukata, Y.2    Kaibuchi, K.3
  • 22
    • 0029943605 scopus 로고    scopus 로고
    • Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways
    • Klippel, A. et al. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol. Cell Biol. 16, 4117-4127 (1996).
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4117-4127
    • Klippel, A.1
  • 23
    • 0030992837 scopus 로고    scopus 로고
    • Signalling through the lipid products of phosphoinositide-3-OH kinase
    • Toker, A. & Cantley, L.C. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387, 673-676 (1997).
    • (1997) Nature , vol.387 , pp. 673-676
    • Toker, A.1    Cantley, L.C.2
  • 24
    • 0038272084 scopus 로고    scopus 로고
    • Membrane-binding and activation mechanism of PTEN
    • Das, S., Dixon, J. E. & Cho, W. Membrane-binding and activation mechanism of PTEN. Proc. Natl Acad. Sci. USA 100, 7491-7496 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7491-7496
    • Das, S.1    Dixon, J.E.2    Cho, W.3
  • 25
    • 0031926623 scopus 로고    scopus 로고
    • Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase
    • Amano, M. et al. Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase. Genes Cells 3, 177-188 (1998).
    • (1998) Genes Cells , vol.3 , pp. 177-188
    • Amano, M.1
  • 26
    • 0344758986 scopus 로고    scopus 로고
    • Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
    • Wang, H. R. et al. Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302, 1775-1779 (2003).
    • (2003) Science , vol.302 , pp. 1775-1779
    • Wang, H.R.1
  • 27
    • 0032506011 scopus 로고    scopus 로고
    • The lipid phosphatase activity of PTEN is critical for its tumor supressor function
    • Myers, M. P. et al. The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc. Natl Acad. Sci. USA 95, 13513-13518 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13513-13518
    • Myers, M.P.1
  • 28
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic, V. et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95, 29-39 (1998).
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1
  • 29
    • 0037337310 scopus 로고    scopus 로고
    • A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling
    • Blagoev, B. et al. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling. Nature Biotechnol. 21, 315-318 (2003).
    • (2003) Nature Biotechnol. , vol.21 , pp. 315-318
    • Blagoev, B.1
  • 30
    • 0037342166 scopus 로고    scopus 로고
    • Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
    • Anzelon, A. N., Wu, H. & Rickert, R.C. Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nature Immunol. 4, 287-294 (2003).
    • (2003) Nature Immunol. , vol.4 , pp. 287-294
    • Anzelon, A.N.1    Wu, H.2    Rickert, R.C.3


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