-
1
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang S, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittman M, Tycko B, Hibshoosh H, Wigler MH, Parsons R: PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997, 275:1943-1947
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittman, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
2
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor B
-
Li D-M, Sun H: TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor B. Cancer Res 1997, 57:2124-2129
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.-M.1
Sun, H.2
-
3
-
-
17144436629
-
Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WKA, Lin H, Ligon AH, Langford LA, Baumgard ML, Mattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DHF, Tavtigian SV: Identification of a candidate tumor suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997, 15:356-362
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Mattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.F.14
Tavtigian, S.V.15
-
4
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Li J, Dahia PLM, Wang SI, Zheng Z, Bose S, Call KM, Tsou HC, Peacocke M, Eng C, Parsons R: Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 1997, 16:64-67
-
(1997)
Nat Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
5
-
-
0031831731
-
PTEN and inherited hamartoma-cancer syndromes
-
Eng C, Peacocke M, PTEN and inherited hamartoma-cancer syndromes. Nat Genet 1998, 19:223
-
(1998)
Nat Genet
, vol.19
, pp. 223
-
-
Eng, C.1
Peacocke, M.2
-
6
-
-
0032146038
-
PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma
-
Levine RL, Cargile CB, Blazes MS, van Rees B, Kurman RJ, Ellenson LH: PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma. Cancer Res 1998, 58:3254-3258
-
(1998)
Cancer Res
, vol.58
, pp. 3254-3258
-
-
Levine, R.L.1
Cargile, C.B.2
Blazes, M.S.3
Van Rees, B.4
Kurman, R.J.5
Ellenson, L.H.6
-
7
-
-
2642643720
-
Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias
-
Maxwell GL, Risinger JL, Gumbs C, Shaw H, Bentley RC, Barrett JC, Berchuck A, Futreal PA: Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias. Cancer Res 1998, 58:2500-2503
-
(1998)
Cancer Res
, vol.58
, pp. 2500-2503
-
-
Maxwell, G.L.1
Risinger, J.L.2
Gumbs, C.3
Shaw, H.4
Bentley, R.C.5
Barrett, J.C.6
Berchuck, A.7
Futreal, P.A.8
-
8
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro H, Blazes MS, Wu R, Cho KR, Bose S, Wang SI, Li J, Parsons R, Ellenson LH: Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 1997, 57:3935-3940
-
(1997)
Cancer Res
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.6
Li, J.7
Parsons, R.8
Ellenson, L.H.9
-
9
-
-
84984777123
-
PTEN1 is frequently mutated in primary endometrial carcinomas
-
Kong D, Suzuki A, Zou T-T, Sakurada A, Kemp LW, Wakatsuki S, Yokohama T, Yamakawa H, Furukawa T, Sato M, Ohuchi N, Sato S, Yin J, Want S, Abraham JM, Souza RF, Smolinksi KN, Meltzer SJ, Horii A: PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet 1997, 17:143-144
-
(1997)
Nat Genet
, vol.17
, pp. 143-144
-
-
Kong, D.1
Suzuki, A.2
Zou, T.-T.3
Sakurada, A.4
Kemp, L.W.5
Wakatsuki, S.6
Yokohama, T.7
Yamakawa, H.8
Furukawa, T.9
Sato, M.10
Ohuchi, N.11
Sato, S.12
Yin, J.13
Want, S.14
Abraham, J.M.15
Souza, R.F.16
Smolinksi, K.N.17
Meltzer, S.J.18
Horii, A.19
-
10
-
-
0032566064
-
Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas
-
Maier D, Zhang ZW, Taylor E, Hamou MF, Gratzl O, van Meir EG, Scott RJ, Merlo A: Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas. Oncogene 1998, 16:3331-3335
-
(1998)
Oncogene
, vol.16
, pp. 3331-3335
-
-
Maier, D.1
Zhang, Z.W.2
Taylor, E.3
Hamou, M.F.4
Gratzl, O.5
Van Meir, E.G.6
Scott, R.J.7
Merlo, A.8
-
11
-
-
0032500108
-
Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas
-
Bose S, Wang SI, Terry MB, Hibshoosh H, Parsons R: Allelic loss of chromosome 10q23 is associated with tumor progression in breast carcinomas. Oncogene 1998, 17:123-127
-
(1998)
Oncogene
, vol.17
, pp. 123-127
-
-
Bose, S.1
Wang, S.I.2
Terry, M.B.3
Hibshoosh, H.4
Parsons, R.5
-
12
-
-
0031916211
-
Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus
-
Singh B, Ittman MM, Krolewski JJ: Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus. Genes Chromosomes Cancer 1998, 21:166-171
-
(1998)
Genes Chromosomes Cancer
, vol.21
, pp. 166-171
-
-
Singh, B.1
Ittman, M.M.2
Krolewski, J.J.3
-
13
-
-
0033003079
-
Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma
-
Feilotter HE, Coulon V, McVeigh JL, Boag AH, Donon-Bonnet F, Duboué B, Latham WCW, Eng C, Mulligan LM, Longy M: Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma. Br J Cancer 1999, 79:718-723
-
(1999)
Br J Cancer
, vol.79
, pp. 718-723
-
-
Feilotter, H.E.1
Coulon, V.2
McVeigh, J.L.3
Boag, A.H.4
Donon-Bonnet, F.5
Duboué, B.6
Latham, W.C.W.7
Eng, C.8
Mulligan, L.M.9
Longy, M.10
-
14
-
-
7144223432
-
PTEN mutations in gliomas and glioneuronal tumors
-
Dürr E-M, Rollbrocker B, Hayashi Y, Peters N, Meyer-Puttlitz B, Louis DN, Schramm J, Wiestler OD, Parsons R, Eng C, von Deimling A: PTEN mutations in gliomas and glioneuronal tumors. Oncogene 1998, 16:2259-2264
-
(1998)
Oncogene
, vol.16
, pp. 2259-2264
-
-
Dürr, E.-M.1
Rollbrocker, B.2
Hayashi, Y.3
Peters, N.4
Meyer-Puttlitz, B.5
Louis, D.N.6
Schramm, J.7
Wiestler, O.D.8
Parsons, R.9
Eng, C.10
Von Deimling, A.11
-
15
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang SI, Puc J, Li J, Bruce JN, Cairns P, Sidransky D, Parsons R: Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 1997, 57:4183-4186
-
(1997)
Cancer Res
, vol.57
, pp. 4183-4186
-
-
Wang, S.I.1
Puc, J.2
Li, J.3
Bruce, J.N.4
Cairns, P.5
Sidransky, D.6
Parsons, R.7
-
16
-
-
0030817576
-
PTEN gene mutations are seen in high-grade but not in low-grade gliomas
-
Rasheed BKA, Stenzel TT, McLendon RE, Parsons R, Friedman AH, Friedman HS, Bigner DD, Bigner SH: PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 1997, 37: 4187-4190
-
(1997)
Cancer Res
, vol.37
, pp. 4187-4190
-
-
Rasheed, B.K.A.1
Stenzel, T.T.2
McLendon, R.E.3
Parsons, R.4
Friedman, A.H.5
Friedman, H.S.6
Bigner, D.D.7
Bigner, S.H.8
-
17
-
-
2642705040
-
Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q
-
Boström J, LudwigCobbers JMJ, Wolter M, Tabatabai G, Weber RG, Lichter P, Collins VP, Reifenberger G: Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res 1998, 58:29-33
-
(1998)
Cancer Res
, vol.58
, pp. 29-33
-
-
Boström, J.1
LudwigCobbers, J.M.J.2
Wolter, M.3
Tabatabai, G.4
Weber, R.G.5
Lichter, P.6
Collins, V.P.7
Reifenberger, G.8
-
18
-
-
0032474749
-
Identification of PTEN/ MMAC1 alterations in uncultured melanomas and melanoma cell lines
-
Tsao HS, Zhang X, Benoit E, Haluska FG: Identification of PTEN/ MMAC1 alterations in uncultured melanomas and melanoma cell lines. Oncogene 1998, 16:3397-3402
-
(1998)
Oncogene
, vol.16
, pp. 3397-3402
-
-
Tsao, H.S.1
Zhang, X.2
Benoit, E.3
Haluska, F.G.4
-
19
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/ MMAC1 in primary breast carcinomas
-
Rhei E, Kang L, Bogomoliniy F, Federici MG, Borgen PI, Boyd J: Mutation analysis of the putative tumor suppressor gene PTEN/ MMAC1 in primary breast carcinomas. Cancer Res 1997, 57:3657-3659
-
(1997)
Cancer Res
, vol.57
, pp. 3657-3659
-
-
Rhei, E.1
Kang, L.2
Bogomoliniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
20
-
-
0022649866
-
The Cowden syndrome: A clinical and genetic study in 21 patients
-
Starink TM, van der Veen JPW, Arwert F, de Waal LP, de Lange GG, Gille JJP, Eriksson AW: The Cowden syndrome: a clinical and genetic study in 21 patients. Clin Genet 1986, 29:222-233
-
(1986)
Clin Genet
, vol.29
, pp. 222-233
-
-
Starink, T.M.1
Van Der Veen, J.P.W.2
Arwert, F.3
De Waal, L.P.4
De Lange, G.G.5
Gille, J.J.P.6
Eriksson, A.W.7
-
21
-
-
0031883606
-
Genetics of Cowden syndrome: Through the looking glass of oncology
-
Eng C: Genetics of Cowden syndrome: through the looking glass of oncology. Int J Oncol 1998, 12:701-710
-
(1998)
Int J Oncol
, vol.12
, pp. 701-710
-
-
Eng, C.1
-
22
-
-
0032461085
-
Mutation of the RET proto-oncogene is correlated with RET immunostaining in subpopulations of cells in sporadic medullary thyroid carcinoma
-
Eng C, Thomas GA, Neuberg DS, Mulligan LM, Healey CS, Houghton C, Frilling A, Raue F, Williams ED, Ponder BAJ: Mutation of the RET proto-oncogene is correlated with RET immunostaining in subpopulations of cells in sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab 1998, 83:4310-4313
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 4310-4313
-
-
Eng, C.1
Thomas, G.A.2
Neuberg, D.S.3
Mulligan, L.M.4
Healey, C.S.5
Houghton, C.6
Frilling, A.7
Raue, F.8
Williams, E.D.9
Ponder, B.A.J.10
-
23
-
-
0028948284
-
Overlapping expression of immunohistochemical markers and synaptophysin mRNA in pheochromocytomas and adenocortical carcinomas
-
Komminoth P, Roth J, Schroder S, Saremaiani P, Heitz PU: Overlapping expression of immunohistochemical markers and synaptophysin mRNA in pheochromocytomas and adenocortical carcinomas. Lab Invest 1995, 72:424-431
-
(1995)
Lab Invest
, vol.72
, pp. 424-431
-
-
Komminoth, P.1
Roth, J.2
Schroder, S.3
Saremaiani, P.4
Heitz, P.U.5
-
24
-
-
0020084203
-
Pancreatic endocrine tumors
-
Heitz PU, Kasper M, Polak JM, Kloppel G: Pancreatic endocrine tumors. Hum Pathol 1982, 13:263-271
-
(1982)
Hum Pathol
, vol.13
, pp. 263-271
-
-
Heitz, P.U.1
Kasper, M.2
Polak, J.M.3
Kloppel, G.4
-
25
-
-
0029865071
-
Antigen retrieval, signal amplification and intensification in immunohistochemistry
-
Werner M, von Wasiekewski R, Komminoth P: Antigen retrieval, signal amplification and intensification in immunohistochemistry. Histochem Cell Biol 1996, 105:253-260
-
(1996)
Histochem Cell Biol
, vol.105
, pp. 253-260
-
-
Werner, M.1
Von Wasiekewski, R.2
Komminoth, P.3
-
26
-
-
0032898096
-
PTEN is inversely correlated with the cell survival factor PKB/Akt and is inactivated by diverse mechanisms in haematologic malignancies
-
in press
-
Dahia PLM, Aguiar RCT, Alberta J, Kum J, Caron S, Sills H, Marsh DJM, Freedman A, Ritz J, Stiles C, Eng C: PTEN is inversely correlated with the cell survival factor PKB/Akt and is inactivated by diverse mechanisms in haematologic malignancies. Hum Mol Genet 1999, in press
-
(1999)
Hum Mol Genet
-
-
Dahia, P.L.M.1
Aguiar, R.C.T.2
Alberta, J.3
Kum, J.4
Caron, S.5
Sills, H.6
Marsh, D.J.M.7
Freedman, A.8
Ritz, J.9
Stiles, C.10
Eng, C.11
-
27
-
-
0030730905
-
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
-
Dahia PLM, Marsh DJ, Zheng Z, Zedenius J, Komminoth P, Frisk T, Wallin G, Parsons R, Longy M, Larsson C, Eng C: Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res 1997, 57:4710-4713
-
(1997)
Cancer Res
, vol.57
, pp. 4710-4713
-
-
Dahia, P.L.M.1
Marsh, D.J.2
Zheng, Z.3
Zedenius, J.4
Komminoth, P.5
Frisk, T.6
Wallin, G.7
Parsons, R.8
Longy, M.9
Larsson, C.10
Eng, C.11
-
28
-
-
0032574718
-
Inactivation of the tumor suppressor PTEN/ MMAC1 in advanced human prostate cancer through loss of expression
-
Whang YE, Wu X, Suzuki H, Reiter RE, Tran C, Vessella RL, Said JW, Isaacs WB, Sawyers CL: Inactivation of the tumor suppressor PTEN/ MMAC1 in advanced human prostate cancer through loss of expression. Proc Natl Acad Sci USA 1998, 95:5246-5250
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5246-5250
-
-
Whang, Y.E.1
Wu, X.2
Suzuki, H.3
Reiter, R.E.4
Tran, C.5
Vessella, R.L.6
Said, J.W.7
Isaacs, W.B.8
Sawyers, C.L.9
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