Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

Nature

Volumn 441, Issue 7092, 2006, Pages 475-482

  Yilmaz, Ömer H ^a,b   Valdez, Riccardo ^a   Theisen, Brian K ^a   Guo, Wei ^c   Ferguson, David O ^a   Wu, Hong ^c   Morrison, Sean J ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE CONTROL; DISEASES; GENES; LIVING SYSTEMS STUDIES; TUMORS;

CANCER STEM CELLS; HAEMATOPOIETIC STEM CELLS; LEUKAEMIA-INITIATING CELLS;

CELLS;

MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAPAMYCIN; PROTEIN KINASE; PTEN PROTEIN, MOUSE;

ANTIBIOTICS; CANCER; DISEASE TREATMENT; RODENT;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; GENE DELETION; HEMATOPOIETIC STEM CELL; IRRADIATION; LEUKEMIA CELL; LEUKEMOGENESIS; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; PHOSPHATASE AND TENSIN HOMOLOGUE GENE; PRIORITY JOURNAL; STEM CELL; TUMOR SUPPRESSOR GENE; ANIMAL; C57BL MOUSE; CANCER TRANSPLANTATION; CELL COUNT; CYTOLOGY; DRUG EFFECT; GENETICS; LEUKEMIA; METABOLISM; PATHOLOGY;

ANIMALS; CELL COUNT; CELL PROLIFERATION; HEMATOPOIETIC STEM CELLS; LEUKEMIA; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PROTEIN KINASES; PTEN PHOSPHOHYDROLASE; SIROLIMUS; TUMOR STEM CELLS;

EID: 33646376411     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04703     Document Type: Article

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