MicroRNA-17∼92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways

EMBO Journal

Volumn 32, Issue 17, 2013, Pages 2377-2391

  Jin, Hyun Yong ^a,b   Oda, Hiroyo ^a,e   Lai, Maoyi ^a   Skalsky, Rebecca L ^c   Bethel, Kelly ^b   Shepherd, Jovan ^a   Kang, Seung Goo ^a   Liu, Wen Hsien ^a   Sabouri Ghomi, Mohsen ^a   Cullen, Bryan R ^c   Rajewsky, Klaus ^d,f   Xiao, Changchun ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SCRIPPS CLINIC   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e 1 7 1 Kohnodai   (Japan)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

lymphoma; miR 17 92; NF B; PAR CLIP; PI3K

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 17; MICRORNA 92; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; (5 (2,4 BIS((3S) 3 METHYLMORPHOLIN 4 YL)PYRIDO(2,3 D)PYRIMIDIN 7 YL) 2 METHOXYPHENYL)METHANOL; (5-(2,4-BIS((3S)-3-METHYLMORPHOLIN-4-YL)PYRIDO(2,3-D)PYRIMIDIN-7-YL)-2-METHOXYPHENYL)METHANOL; 4(2' AMINOETHYL)AMINO 1,8 DIMETHYLIMIDAZO(1,2 A)QUINOXALINE; 4(2'-AMINOETHYL)AMINO-1,8-DIMETHYLIMIDAZO(1,2-A)QUINOXALINE; HOMEODOMAIN PROTEIN; IMIDAZOLE DERIVATIVE; MIRN17 92 MICRORNA, HUMAN; MIRN17-92 MICRORNA, HUMAN; MORPHOLINE DERIVATIVE; QUINOXALINE DERIVATIVE; RAG 1 PROTEIN; RAG-1 PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CANCER SIZE; CANCER SURVIVAL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE TARGETING; HUMAN; HUMAN CELL; LARGE CELL LYMPHOMA; LYMPHOMA; LYMPHOMA CELL; MITOCHONDRION; MOUSE; NONHUMAN; ONCOGENE MYC; PENETRANCE; PRIORITY JOURNAL; ANIMAL; BURKITT LYMPHOMA; C57BL MOUSE; CELL SURVIVAL; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; REPRODUCIBILITY; TRANSGENIC MOUSE; ANTAGONISTS AND INHIBITORS;

MUS; MUS MUSCULUS;

ANIMALS; B-LYMPHOCYTES; BURKITT LYMPHOMA; CELL PROLIFERATION; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; IMIDAZOLES; LYMPHOMA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; MORPHOLINES; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; QUINOXALINES; REPRODUCIBILITY OF RESULTS;

EID: 84883310620     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.178     Document Type: Article

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