Negative regulation of myofibroblast differentiation by PTEN (phosphatase and tensin homolog deleted on chromosome 10)

American Journal of Respiratory and Critical Care Medicine

Volumn 173, Issue 1, 2006, Pages 112-121

  White, Eric S ^a   Atrasz, Rachelle G ^b   Hu, Biao ^b   Phan, Sem H ^b   Stambolic, Vuk ^b   Mak, Tak W ^b   Hogaboam, Cory M ^b   Flaherty, Kevin R ^b   Martinez, Fernando J ^b   Kontos, Christopher D ^b   Toews, Galen B ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

Fibrosis; Myofibroblast; Phosphatase; PTEN; Smooth muscle actin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ALPHA SMOOTH MUSCLE ACTIN; BISPEROXO(PYRIDINE 2 CARBOXYL)OXOVANADATE; BLEOMYCIN; COLLAGEN; ENZYME INHIBITOR; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMOSOME 10; CONTROLLED STUDY; EMBRYO; FIBROBLAST; HUMAN; HUMAN TISSUE; LUNG BIOPSY; LUNG FIBROSIS; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; UPREGULATION; WILD TYPE;

ACTINS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; FIBROBLASTS; FIBROSIS; HUMANS; LUNG DISEASES, INTERSTITIAL; MICE; MICE, INBRED C57BL; PTEN PHOSPHOHYDROLASE; PULMONARY FIBROSIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 30344485686     PISSN: 1073449X     EISSN: 1073449X     Source Type: Journal    
DOI: 10.1164/rccm.200507-1058OC     Document Type: Article

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