-
1
-
-
0025908897
-
The Ras protein family: Evolutionary tree and role of conserved amino acids
-
2029511
-
Valencia A, Chardin P, Wittinghofer A, Sander C (1991) The Ras protein family: evolutionary tree and role of conserved amino acids. Biochemistry 30:4637-4648
-
(1991)
Biochemistry
, vol.30
, pp. 4637-4648
-
-
Valencia, A.1
Chardin, P.2
Wittinghofer, A.3
Sander, C.4
-
3
-
-
84876590830
-
New insight into the molecular switch mechanism of human Rho family proteins: Shifting a paradigm
-
23096567
-
Jaiswal M, Fansa EK, Dvorsky R, Ahmadian MR (2013) New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm. Biol Chem 394:89-95
-
(2013)
Biol Chem
, vol.394
, pp. 89-95
-
-
Jaiswal, M.1
Fansa, E.K.2
Dvorsky, R.3
Ahmadian, M.R.4
-
4
-
-
34648844192
-
Taking Rho GTPases to the next level: The cellular functions of atypical Rho GTPases
-
DOI 10.1016/j.yexcr.2007.07.022, PII S0014482707003588
-
Aspenstrom P, Ruusala A, Pacholsky D (2007) Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases. Exp Cell Res 313:3673-3679 (Pubitemid 47464235)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.17
, pp. 3673-3679
-
-
Aspenstrom, P.1
Ruusala, A.2
Pacholsky, D.3
-
5
-
-
33644843642
-
Function and regulation of Rnd proteins
-
DOI 10.1038/nrm1788, PII N1788
-
Chardin P (2006) Function and regulation of Rnd proteins. Nat Rev Mol Cell Biol 7:54-62 (Pubitemid 43361572)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.1
, pp. 54-62
-
-
Chardin, P.1
-
6
-
-
0037081677
-
The Rho GTPase family: A Racs to Wrchs story
-
Wherlock M, Mellor H (2002) The Rho GTPase family: a Racs to Wrchs story. J Cell Sci 115:239-240 (Pubitemid 34145173)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.2
, pp. 239-240
-
-
Wherlock, M.1
Mellor, H.2
-
7
-
-
33845420563
-
RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress
-
DOI 10.1016/j.cub.2006.10.056, PII S0960982206024316
-
Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW (2006) RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Curr Biol 16:2466-2472 (Pubitemid 44894910)
-
(2006)
Current Biology
, vol.16
, Issue.24
, pp. 2466-2472
-
-
Ongusaha, P.P.1
Kim, H.-G.2
Boswell, S.A.3
Ridley, A.J.4
Der, C.J.5
Dotto, G.P.6
Kim, Y.-B.7
Aaronson, S.A.8
Lee, S.W.9
-
8
-
-
0035878110
-
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1
-
DOI 10.1101/gad.894301
-
Tao W, Pennica D, Xu L, Kalejta RF, Levine AJ (2001) Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1. Genes Dev 15:1796-1807 (Pubitemid 32905637)
-
(2001)
Genes and Development
, vol.15
, Issue.14
, pp. 1796-1807
-
-
Tao, W.1
Pennica, D.2
Xu, L.3
Kalejta, R.F.4
Levine, A.J.5
-
10
-
-
33845868501
-
Evolution of the Rho family of Ras-like GTPases in eukaryotes
-
DOI 10.1093/molbev/msl145
-
Boureux A, Vignal E, Faure S, Fort P (2007) Evolution of the Rho family of Ras-like GTPases in eukaryotes. Mol Biol Evol 24:203-216 (Pubitemid 46026295)
-
(2007)
Molecular Biology and Evolution
, vol.24
, Issue.1
, pp. 203-216
-
-
Boureux, A.1
Vignal, E.2
Faure, S.3
Fort, P.4
-
11
-
-
0037102301
-
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
-
12181570
-
Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW (2002) Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 418:790-793
-
(2002)
Nature
, vol.418
, pp. 790-793
-
-
Eden, S.1
Rohatgi, R.2
Podtelejnikov, A.V.3
Mann, M.4
Kirschner, M.W.5
-
12
-
-
69949185998
-
Coordination of Rho GTPase activities during cell protrusion
-
2885353 19693013
-
Machacek M, Hodgson L, Welch C, Elliott H, Pertz O, Nalbant P, Abell A, Johnson GL, Hahn KM, Danuser G (2009) Coordination of Rho GTPase activities during cell protrusion. Nature 461:99-103
-
(2009)
Nature
, vol.461
, pp. 99-103
-
-
Machacek, M.1
Hodgson, L.2
Welch, C.3
Elliott, H.4
Pertz, O.5
Nalbant, P.6
Abell, A.7
Johnson, G.L.8
Hahn, K.M.9
Danuser, G.10
-
13
-
-
0037162289
-
Cell cycle-regulated phosphorylation of p21-activated kinase 1
-
DOI 10.1016/S0960-9822(02)00931-4, PII S0960982202009314
-
Thiel DA, Reeder MK, Pfaff A, Coleman TR, Sells MA, Chernoff J (2002) Cell cycle-regulated phosphorylation of p21-activated kinase 1. Curr Biol 12:1227-1232 (Pubitemid 34801171)
-
(2002)
Current Biology
, vol.12
, Issue.14
, pp. 1227-1232
-
-
Thiel, D.A.1
Reeder, M.K.2
Pfaff, A.3
Coleman, T.R.4
Sells, M.A.5
Chernoff, J.6
-
14
-
-
1842426910
-
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration
-
DOI 10.1242/jcs.00997
-
Wells CM, Walmsley M, Ooi S, Tybulewicz V, Ridley AJ (2004) Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J Cell Sci 117:1259-1268 (Pubitemid 38456106)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.7
, pp. 1259-1268
-
-
Wells, C.M.1
Walmsley, M.2
Ooi, S.3
Tybulewicz, V.4
Ridley, A.J.5
-
15
-
-
79957466415
-
Spatiotemporal control of small GTPases with light using the LOV domain
-
3407667 21601095
-
Wu YI, Wang X, He L, Montell D, Hahn KM (2011) Spatiotemporal control of small GTPases with light using the LOV domain. Methods Enzymol 497:393-407
-
(2011)
Methods Enzymol
, vol.497
, pp. 393-407
-
-
Wu, Y.I.1
Wang, X.2
He, L.3
Montell, D.4
Hahn, K.M.5
-
16
-
-
69949104482
-
A genetically encoded photoactivatable Rac controls the motility of living cells
-
2766670 19693014
-
Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlman B, Hahn KM (2009) A genetically encoded photoactivatable Rac controls the motility of living cells. Nature 461:104-108
-
(2009)
Nature
, vol.461
, pp. 104-108
-
-
Wu, Y.I.1
Frey, D.2
Lungu, O.I.3
Jaehrig, A.4
Schlichting, I.5
Kuhlman, B.6
Hahn, K.M.7
-
17
-
-
77953123080
-
Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo
-
2929827 20473296
-
Wang X, He L, Wu YI, Hahn KM, Montell DJ (2010) Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nat Cell Biol 12:591-597
-
(2010)
Nat Cell Biol
, vol.12
, pp. 591-597
-
-
Wang, X.1
He, L.2
Wu, Y.I.3
Hahn, K.M.4
Montell, D.J.5
-
18
-
-
67649675530
-
Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling
-
2676027 19269969
-
Zhang Y, Rivera Rosado LA, Moon SY, Zhang B (2009) Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling. J Biol Chem 284:12956-12965
-
(2009)
J Biol Chem
, vol.284
, pp. 12956-12965
-
-
Zhang, Y.1
Rivera Rosado, L.A.2
Moon, S.Y.3
Zhang, B.4
-
19
-
-
46649097870
-
CAMP inhibits cell migration by interfering with Rac-induced lamellipodium formation
-
2376213 18353776
-
Chen L, Zhang JJ, Huang XY (2008) cAMP inhibits cell migration by interfering with Rac-induced lamellipodium formation. J Biol Chem 283:13799-13805
-
(2008)
J Biol Chem
, vol.283
, pp. 13799-13805
-
-
Chen, L.1
Zhang, J.J.2
Huang, X.Y.3
-
20
-
-
57749118818
-
Phospholipase Cgamma1 is required for metastasis development and progression
-
19074886
-
Sala G, Dituri F, Raimondi C, Previdi S, Maffucci T, Mazzoletti M, Rossi C, Iezzi M, Lattanzio R, Piantelli M, Iacobelli S, Broggini M, Falasca M (2008) Phospholipase Cgamma1 is required for metastasis development and progression. Cancer Res 68:10187-10196
-
(2008)
Cancer Res
, vol.68
, pp. 10187-10196
-
-
Sala, G.1
Dituri, F.2
Raimondi, C.3
Previdi, S.4
Maffucci, T.5
Mazzoletti, M.6
Rossi, C.7
Iezzi, M.8
Lattanzio, R.9
Piantelli, M.10
Iacobelli, S.11
Broggini, M.12
Falasca, M.13
-
21
-
-
0032568650
-
The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments
-
DOI 10.1073/pnas.95.11.6181
-
Mullins RD, Heuser JA, Pollard TD (1998) The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci USA 95:6181-6186 (Pubitemid 28248985)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6181-6186
-
-
Mullins, R.D.1
Heuser, J.A.2
Pollard, T.D.3
-
22
-
-
0033838716
-
Regulation of cell function by Rho family GTPases
-
10852111
-
Bokoch GM (2000) Regulation of cell function by Rho family GTPases. Immunol Res 21:139-148
-
(2000)
Immunol Res
, vol.21
, pp. 139-148
-
-
Bokoch, G.M.1
-
23
-
-
0033194037
-
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
-
Edwards DC, Sanders LC, Bokoch GM, Gill GN (1999) Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. Nat Cell Biol 1:253-259 (Pubitemid 129495774)
-
(1999)
Nature Cell Biology
, vol.1
, Issue.5
, pp. 253-259
-
-
Edwards, D.C.1
Sanders, L.C.2
Bokoch, G.M.3
Gill, G.N.4
-
24
-
-
1642446043
-
P-41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate
-
DOI 10.1038/sj.embor.7400079
-
Vadlamudi RK, Li F, Barnes CJ, Bagheri-Yarmand R, Kumar R (2004) p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate. EMBO Rep 5:154-160 (Pubitemid 38401194)
-
(2004)
EMBO Reports
, vol.5
, Issue.2
, pp. 154-160
-
-
Vadlamudi, R.K.1
Li, F.2
Barnes, C.J.3
Bagheri-Yarmand, R.4
Kumar, R.5
-
25
-
-
80555126205
-
P21-activated kinase 1: PAK'ed with potential
-
3248206 21653999
-
Ong CC, Jubb AM, Zhou W, Haverty PM, Harris AL, Belvin M, Friedman LS, Koeppen H, Hoeflich KP (2011) p21-activated kinase 1: PAK'ed with potential. Oncotarget 2:491-496
-
(2011)
Oncotarget
, vol.2
, pp. 491-496
-
-
Ong, C.C.1
Jubb, A.M.2
Zhou, W.3
Haverty, P.M.4
Harris, A.L.5
Belvin, M.6
Friedman, L.S.7
Koeppen, H.8
Hoeflich, K.P.9
-
26
-
-
33745714519
-
Nuclear p21-activated kinase 1 in breast cancer packs off tamoxifen sensitivity
-
16778166
-
Rayala SK, Molli PR, Kumar R (2006) Nuclear p21-activated kinase 1 in breast cancer packs off tamoxifen sensitivity. Cancer Res 66:5985-5988
-
(2006)
Cancer Res
, vol.66
, pp. 5985-5988
-
-
Rayala, S.K.1
Molli, P.R.2
Kumar, R.3
-
27
-
-
0032585635
-
Rac1 is required for the formation of three germ layers during gastrulation
-
Sugihara K, Nakatsuji N, Nakamura K, Nakao K, Hashimoto R, Otani H, Sakagami H, Kondo H, Nozawa S, Aiba A, Katsuki M (1998) Rac1 is required for the formation of three germ layers during gastrulation. Oncogene 17:3427-3433 (Pubitemid 29050677)
-
(1998)
Oncogene
, vol.17
, Issue.26
, pp. 3427-3433
-
-
Sugihara, K.1
Nakatsuji, N.2
Nakamura, K.3
Nakao, K.4
Hashimoto, R.5
Otani, H.6
Sakagami, H.7
Kondo, H.8
Nozawa, S.9
Aiba, A.10
Katsuki, M.11
-
28
-
-
34250693117
-
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development
-
DOI 10.1083/jcb.200610108
-
Benninger Y, Thurnherr T, Pereira JA, Krause S, Wu X, Chrostek-Grashoff A, Herzog D, Nave KA, Franklin RJ, Meijer D, Brakebusch C, Suter U, Relvas JB (2007) Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol 177:1051-1061 (Pubitemid 46955709)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.6
, pp. 1051-1061
-
-
Benninger, Y.1
Thurnherr, T.2
Pereira, J.A.3
Krause, S.4
Wu, X.5
Chrostek-Grashoff, A.6
Herzog, D.7
Nave, K.-A.8
Franklin, R.J.M.9
Meijer, D.10
Brakebusch, C.11
Suter, U.12
Relvas, J.B.13
-
29
-
-
52649136968
-
Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development
-
2518885 18579797
-
Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y (2008) Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood 112:1767-1775
-
(2008)
Blood
, vol.112
, pp. 1767-1775
-
-
Guo, F.1
Cancelas, J.A.2
Hildeman, D.3
Williams, D.A.4
Zheng, Y.5
-
30
-
-
0142116231
-
Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling
-
DOI 10.1126/science.1089709
-
Walmsley MJ, Ooi SK, Reynolds LF, Smith SH, Ruf S, Mathiot A, Vanes L, Williams DA, Cancro MP, Tybulewicz VL (2003) Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. Science 302:459-462 (Pubitemid 37296274)
-
(2003)
Science
, vol.302
, Issue.5644
, pp. 459-462
-
-
Walmsley, M.J.1
Ooi, S.K.T.2
Reynolds, L.F.3
Smith, S.H.4
Ruf, S.5
Mathiot, A.6
Vanes, L.7
Williams, D.A.8
Cancro, M.P.9
Tybulewicz, V.L.J.10
-
31
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
18719708
-
Heasman SJ, Ridley AJ (2008) Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9:690-701
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
32
-
-
20744460575
-
Generation and characterization of Rac3 knockout mice
-
DOI 10.1128/MCB.25.13.5763-5776.2005
-
Corbetta S, Gualdoni S, Albertinazzi C, Paris S, Croci L, Consalez GG, de Curtis I (2005) Generation and characterization of Rac3 knockout mice. Mol Cell Biol 25:5763-5776 (Pubitemid 40853608)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5763-5776
-
-
Corbetta, S.1
Gualdoni, S.2
Albertinazzi, C.3
Paris, S.4
Croci, L.5
Consalez, G.G.6
De Curtis, I.7
-
33
-
-
84864258996
-
A landscape of driver mutations in melanoma
-
3600117 22817889
-
Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L (2012) A landscape of driver mutations in melanoma. Cell 150:251-263
-
(2012)
Cell
, vol.150
, pp. 251-263
-
-
Hodis, E.1
Watson, I.R.2
Kryukov, G.V.3
Arold, S.T.4
Imielinski, M.5
Theurillat, J.P.6
Nickerson, E.7
Auclair, D.8
Li, L.9
Place, C.10
Dicara, D.11
Ramos, A.H.12
Lawrence, M.S.13
Cibulskis, K.14
Sivachenko, A.15
Voet, D.16
Saksena, G.17
Stransky, N.18
Onofrio, R.C.19
Winckler, W.20
Ardlie, K.21
Wagle, N.22
Wargo, J.23
Chong, K.24
Morton, D.L.25
Stemke-Hale, K.26
Chen, G.27
Noble, M.28
Meyerson, M.29
Ladbury, J.E.30
Davies, M.A.31
Gershenwald, J.E.32
Wagner, S.N.33
Hoon, D.S.34
Schadendorf, D.35
Lander, E.S.36
Gabriel, S.B.37
Getz, G.38
Garraway, L.A.39
Chin, L.40
more..
-
34
-
-
84865684161
-
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
-
3432702 22842228
-
Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bosenberg M, Sznol M, Kluger HM, Brash DE, Stern DF, Materin MA, Lo RS, Mane S, Ma S, Kidd KK, Hayward NK, Lifton RP, Schlessinger J, Boggon TJ, Halaban R (2012) Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet 44:1006-1014
-
(2012)
Nat Genet
, vol.44
, pp. 1006-1014
-
-
Krauthammer, M.1
Kong, Y.2
Ha, B.H.3
Evans, P.4
Bacchiocchi, A.5
McCusker, J.P.6
Cheng, E.7
Davis, M.J.8
Goh, G.9
Choi, M.10
Ariyan, S.11
Narayan, D.12
Dutton-Regester, K.13
Capatana, A.14
Holman, E.C.15
Bosenberg, M.16
Sznol, M.17
Kluger, H.M.18
Brash, D.E.19
Stern, D.F.20
Materin, M.A.21
Lo, R.S.22
Mane, S.23
Ma, S.24
Kidd, K.K.25
Hayward, N.K.26
Lifton, R.P.27
Schlessinger, J.28
Boggon, T.J.29
Halaban, R.30
more..
-
35
-
-
0033581944
-
Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
-
10597294
-
Jordan P, Brazao R, Boavida MG, Gespach C, Chastre E (1999) Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors. Oncogene 18:6835-6839
-
(1999)
Oncogene
, vol.18
, pp. 6835-6839
-
-
Jordan, P.1
Brazao, R.2
Boavida, M.G.3
Gespach, C.4
Chastre, E.5
-
36
-
-
0347379871
-
Tumor-related Alternatively Spliced Rac1b Is Not Regulated by Rho-GDP Dissociation Inhibitors and Exhibits Selective Downstream Signaling
-
DOI 10.1074/jbc.M308215200
-
Matos P, Collard JG, Jordan P (2003) Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling. J Biol Chem 278:50442-50448 (Pubitemid 37548889)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 50442-50448
-
-
Matos, P.1
Collard, J.G.2
Jordan, P.3
-
37
-
-
11244313840
-
Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation
-
DOI 10.1038/sj.onc.1208182
-
Singh A, Karnoub AE, Palmby TR, Lengyel E, Sondek J, Der CJ (2004) Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene 23:9369-9380 (Pubitemid 40069669)
-
(2004)
Oncogene
, vol.23
, Issue.58
, pp. 9369-9380
-
-
Singh, A.1
Karnoub, A.E.2
Palmby, T.R.3
Lengyel, E.4
Sondek, J.5
Der, C.J.6
-
38
-
-
37849050182
-
Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process
-
18093184
-
Visvikis O, Lores P, Boyer L, Chardin P, Lemichez E, Gacon G (2008) Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process. FEBS J 275:386-396
-
(2008)
FEBS J
, vol.275
, pp. 386-396
-
-
Visvikis, O.1
Lores, P.2
Boyer, L.3
Chardin, P.4
Lemichez, E.5
Gacon, G.6
-
39
-
-
5044230434
-
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus
-
DOI 10.1016/j.gene.2004.07.019, PII S0378111904004615
-
Ladd PD, Butler JS, Skalnik DG (2004) Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. Gene 341:323-333 (Pubitemid 39335907)
-
(2004)
Gene
, vol.341
, Issue.1-2
, pp. 323-333
-
-
Ladd, P.D.1
Sergesketter Butler, J.2
Skalnik, D.G.3
-
40
-
-
0030824832
-
Characterization of RAC3, a novel member of the Rho family
-
DOI 10.1074/jbc.272.33.20384
-
Haataja L, Groffen J, Heisterkamp N (1997) Characterization of RAC3, a novel member of the Rho family. J Biol Chem 272:20384-20388 (Pubitemid 27355588)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.33
, pp. 20384-20388
-
-
Haataja, L.1
Groffen, J.2
Heisterkamp, N.3
-
42
-
-
0033082165
-
Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense
-
Roberts AW, Kim C, Zhen L, Lowe JB, Kapur R, Petryniak B, Spaetti A, Pollock JD, Borneo JB, Bradford GB, Atkinson SJ, Dinauer MC, Williams DA (1999) Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity 10:183-196 (Pubitemid 29115624)
-
(1999)
Immunity
, vol.10
, Issue.2
, pp. 183-196
-
-
Roberts, A.W.1
Chaekyun, K.2
Zhen, L.3
Lowe, J.B.4
Kapur, R.5
Petryniak, B.6
Spaetti, A.7
Pollock, J.D.8
Borneo, J.B.9
Bradford, G.B.10
Atkinson, S.J.11
Dinauer, M.C.12
Williams, D.A.13
-
43
-
-
0034283717
-
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency
-
Williams DA, Tao W, Yang F, Kim C, Gu Y, Mansfield P, Levine JE, Petryniak B, Derrow CW, Harris C, Jia B, Zheng Y, Ambruso DR, Lowe JB, Atkinson SJ, Dinauer MC, Boxer L (2000) Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. Blood 96:1646-1654 (Pubitemid 30661042)
-
(2000)
Blood
, vol.96
, Issue.5
, pp. 1646-1654
-
-
Williams, D.A.1
Tao, W.2
Yang, F.3
Kim, C.4
Gu, Y.5
Mansfield, P.6
Levine, J.E.7
Petryniak, B.8
Derrow, C.W.9
Harris, C.10
Jia, B.11
Zheng, Y.12
Ambruso, D.R.13
Lowe, J.B.14
Atkinson, S.J.15
Dinauer, M.C.16
Boxer, L.17
-
44
-
-
8444239999
-
Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles
-
Yamauchi A, Kim C, Li S, Marchal CC, Towe J, Atkinson SJ, Dinauer MC (2004) Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles. J Immunol 173:5971-5979 (Pubitemid 39487751)
-
(2004)
Journal of Immunology
, vol.173
, Issue.10
, pp. 5971-5979
-
-
Yamauchi, A.1
Kim, C.2
Li, S.3
Marchal, C.C.4
Towe, J.5
Atkinson, S.J.6
Dinauer, M.C.7
-
45
-
-
0037215397
-
Regulation of neutrophil function by Rac GTPases
-
DOI 10.1097/00062752-200301000-00003
-
Dinauer MC (2003) Regulation of neutrophil function by Rac GTPases. Curr Opin Hematol 10:8-15 (Pubitemid 36020712)
-
(2003)
Current Opinion in Hematology
, vol.10
, Issue.1
, pp. 8-15
-
-
Dinauer, M.C.1
-
46
-
-
1642462459
-
GTPases and reactive oxygen species: Switches for killing and signaling
-
DOI 10.1242/jcs.00937
-
Werner E (2004) GTPases and reactive oxygen species: switches for killing and signaling. J Cell Sci 117:143-153 (Pubitemid 38128895)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.2
, pp. 143-153
-
-
Werner, E.1
-
47
-
-
0034602690
-
Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway
-
DOI 10.1073/pnas.97.1.185
-
Mira JP, Benard V, Groffen J, Sanders LC, Knaus UG (2000) Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway. Proc Natl Acad Sci USA 97:185-189 (Pubitemid 30055805)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.1
, pp. 185-189
-
-
Mira, J.-P.1
Benard, V.2
Groffen, J.3
Sanders, L.C.4
Knaus, U.G.5
-
48
-
-
0033934921
-
The small GTPase RAC3 gene is located within chromosome band 17q25.3 outside and telomeric of a region commonly deleted in breast and ovarian tumours
-
Morris CM, Haataja L, McDonald M, Gough S, Markie D, Groffen J, Heisterkamp N (2000) The small GTPase RAC3 gene is located within chromosome band 17q25.3 outside and telomeric of a region commonly deleted in breast and ovarian tumours. Cytogenet Cell Genet 89:18-23 (Pubitemid 30435251)
-
(2000)
Cytogenetics and Cell Genetics
, vol.89
, Issue.1-2
, pp. 18-23
-
-
Morris, C.M.1
Haataja, L.2
McDonald, M.3
Gough, S.4
Markie, D.5
Groffen, J.6
Heisterkamp, N.7
-
49
-
-
31644445194
-
Activation of Rac1 by RhoG regulates cell migration
-
DOI 10.1242/jcs.02720
-
Katoh H, Hiramoto K, Negishi M (2006) Activation of Rac1 by RhoG regulates cell migration. J Cell Sci 119:56-65 (Pubitemid 43169298)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.1
, pp. 56-65
-
-
Katoh, H.1
Hiramoto, K.2
Negishi, M.3
-
50
-
-
45549093056
-
Investigating the function of Rho family GTPases during Salmonella/host cell interactions
-
2677710 18374162
-
Patel JC, Galan JE (2008) Investigating the function of Rho family GTPases during Salmonella/host cell interactions. Methods Enzymol 439:145-158
-
(2008)
Methods Enzymol
, vol.439
, pp. 145-158
-
-
Patel, J.C.1
Galan, J.E.2
-
51
-
-
66149150664
-
Yersinia enterocolitica differentially modulates RhoG activity in host cells
-
19208761
-
Roppenser B, Roder A, Hentschke M, Ruckdeschel K, Aepfelbacher M (2009) Yersinia enterocolitica differentially modulates RhoG activity in host cells. J Cell Sci 122:696-705
-
(2009)
J Cell Sci
, vol.122
, pp. 696-705
-
-
Roppenser, B.1
Roder, A.2
Hentschke, M.3
Ruckdeschel, K.4
Aepfelbacher, M.5
-
52
-
-
77951719965
-
Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors
-
2861620 20237158
-
Samson T, Welch C, Monaghan-Benson E, Hahn KM, Burridge K (2010) Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors. Mol Biol Cell 21:1629-1642
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1629-1642
-
-
Samson, T.1
Welch, C.2
Monaghan-Benson, E.3
Hahn, K.M.4
Burridge, K.5
-
53
-
-
84864306956
-
Cooperative activation of PI3K by Ras and Rho family small GTPases
-
3729028 22683270
-
Yang HW, Shin MG, Lee S, Kim JR, Park WS, Cho KH, Meyer T, Do Heo W (2012) Cooperative activation of PI3K by Ras and Rho family small GTPases. Mol Cell 47:281-290
-
(2012)
Mol Cell
, vol.47
, pp. 281-290
-
-
Yang, H.W.1
Shin, M.G.2
Lee, S.3
Kim, J.R.4
Park, W.S.5
Cho, K.H.6
Meyer, T.7
Do Heo, W.8
-
54
-
-
21244478650
-
Rho GTPase expression in tumourigenesis: Evidence for a significant link
-
DOI 10.1002/bies.20238
-
Gomez del Pulgar T, Benitah SA, Valeron PF, Espina C, Lacal JC (2005) Rho GTPase expression in tumourigenesis: evidence for a significant link. BioEssays 27:602-613 (Pubitemid 40896091)
-
(2005)
BioEssays
, vol.27
, Issue.6
, pp. 602-613
-
-
Gomez Del Pulgar, T.1
Benitah, S.A.2
Valeron, P.F.3
Espina, C.4
Lacal, J.C.5
-
56
-
-
84884168966
-
RhoA, RhoB and RhoC have different roles in cancer cell migration
-
23488932
-
Ridley AJ (2013) RhoA, RhoB and RhoC have different roles in cancer cell migration. J Microsc 251:242-249
-
(2013)
J Microsc
, vol.251
, pp. 242-249
-
-
Ridley, A.J.1
-
57
-
-
24644519086
-
The challenges of abundance: Epithelial junctions and small GTPase signalling
-
DOI 10.1016/j.ceb.2005.08.012, PII S0955067405001158
-
Braga VM, Yap AS (2005) The challenges of abundance: epithelial junctions and small GTPase signalling. Curr Opin Cell Biol 17:466-474 (Pubitemid 41267160)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.5 SPEC. ISS.
, pp. 466-474
-
-
Braga, V.M.M.1
Yap, A.S.2
-
58
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
DOI 10.1038/nrc1075
-
Friedl P, Wolf K (2003) Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3:362-374 (Pubitemid 37328856)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
60
-
-
54949144636
-
RhoC is essential for angiogenesis induced by hepatocellular carcinoma cells via regulation of endothelial cell organization
-
19016761
-
Wang W, Wu F, Fang F, Tao Y, Yang L (2008) RhoC is essential for angiogenesis induced by hepatocellular carcinoma cells via regulation of endothelial cell organization. Cancer Sci 99:2012-2018
-
(2008)
Cancer Sci
, vol.99
, pp. 2012-2018
-
-
Wang, W.1
Wu, F.2
Fang, F.3
Tao, Y.4
Yang, L.5
-
61
-
-
70349305426
-
Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity
-
19642867
-
Dietrich KA, Schwarz R, Liska M, Grass S, Menke A, Meister M, Kierschke G, Langle C, Genze F, Giehl K (2009) Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity. Biol Chem 390:1063-1077
-
(2009)
Biol Chem
, vol.390
, pp. 1063-1077
-
-
Dietrich, K.A.1
Schwarz, R.2
Liska, M.3
Grass, S.4
Menke, A.5
Meister, M.6
Kierschke, G.7
Langle, C.8
Genze, F.9
Giehl, K.10
-
62
-
-
0033983938
-
Regulation of endocytic traffic by Rho family GTPases
-
DOI 10.1016/S0962-8924(99)01710-9, PII S0962892499017109
-
Ellis S, Mellor H (2000) Regulation of endocytic traffic by rho family GTPases. Trends Cell Biol 10:85-88 (Pubitemid 30110689)
-
(2000)
Trends in Cell Biology
, vol.10
, Issue.3
, pp. 85-88
-
-
Ellis, S.1
Mellor, H.2
-
63
-
-
33748994545
-
Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
-
DOI 10.1016/j.tcb.2006.08.006, PII S0962892406002236, Membrane Dynamics
-
Ridley AJ (2006) Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 16:522-529 (Pubitemid 44444995)
-
(2006)
Trends in Cell Biology
, vol.16
, Issue.10
, pp. 522-529
-
-
Ridley, A.J.1
-
64
-
-
0034808219
-
RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells
-
DOI 10.1128/MCB.21.20.6906-6912.2001
-
Liu AX, Rane N, Liu JP, Prendergast GC (2001) RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells. Mol Cell Biol 21:6906-6912 (Pubitemid 32911251)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.20
, pp. 6906-6912
-
-
Liu, A.-X.1
Rane, N.2
Liu, J.-P.3
Prendergast, G.C.4
-
65
-
-
52049115446
-
RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha
-
18524772
-
Ho TT, Merajver SD, Lapiere CM, Nusgens BV, Deroanne CF (2008) RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha. J Biol Chem 283:21588-21598
-
(2008)
J Biol Chem
, vol.283
, pp. 21588-21598
-
-
Ho, T.T.1
Merajver, S.D.2
Lapiere, C.M.3
Nusgens, B.V.4
Deroanne, C.F.5
-
66
-
-
79958232399
-
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets
-
3166870 21576392
-
Vega FM, Fruhwirth G, Ng T, Ridley AJ (2011) RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol 193:655-665
-
(2011)
J Cell Biol
, vol.193
, pp. 655-665
-
-
Vega, F.M.1
Fruhwirth, G.2
Ng, T.3
Ridley, A.J.4
-
67
-
-
0030040750
-
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
-
Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J (1996) Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J 15:510-519 (Pubitemid 26044564)
-
(1996)
EMBO Journal
, vol.15
, Issue.3
, pp. 510-519
-
-
Lang, P.1
Gesbert, F.2
Delespine-Carmagnat, M.3
Stancou, R.4
Pouchelet, M.5
Bertoglio, J.6
-
68
-
-
0034647534
-
Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle
-
10783386
-
Sauzeau V, Le Jeune H, Cario-Toumaniantz C, Smolenski A, Lohmann SM, Bertoglio J, Chardin P, Pacaud P, Loirand G (2000) Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle. J Biol Chem 275:21722-21729
-
(2000)
J Biol Chem
, vol.275
, pp. 21722-21729
-
-
Sauzeau, V.1
Le Jeune, H.2
Cario-Toumaniantz, C.3
Smolenski, A.4
Lohmann, S.M.5
Bertoglio, J.6
Chardin, P.7
Pacaud, P.8
Loirand, G.9
-
69
-
-
18344374044
-
Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: Role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats
-
Savoia C, Tabet F, Yao G, Schiffrin EL, Touyz RM (2005) Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats. J Hypertens 23:1037-1045 (Pubitemid 40637923)
-
(2005)
Journal of Hypertension
, vol.23
, Issue.5
, pp. 1037-1045
-
-
Savoia, C.1
Tabet, F.2
Yao, G.3
Schiffrin, E.L.4
Touyz, R.M.5
-
70
-
-
84859043541
-
Divergence of Rho residue 43 impacts GEF activity
-
3398911 22673745
-
Sloan CM, Quinn CV, Peters JP, Farley J, Goetzinger C, Wernli M, DeMali KA, Ellerbroek SM (2012) Divergence of Rho residue 43 impacts GEF activity. Small GTPases 3:15-22
-
(2012)
Small GTPases
, vol.3
, pp. 15-22
-
-
Sloan, C.M.1
Quinn, C.V.2
Peters, J.P.3
Farley, J.4
Goetzinger, C.5
Wernli, M.6
Demali, K.A.7
Ellerbroek, S.M.8
-
71
-
-
36849088611
-
Cdc42 regulates cofilin during the establishment of neuronal polarity
-
DOI 10.1523/JNEUROSCI.3322-07.2007
-
Garvalov BK, Flynn KC, Neukirchen D, Meyn L, Teusch N, Wu X, Brakebusch C, Bamburg JR, Bradke F (2007) Cdc42 regulates cofilin during the establishment of neuronal polarity. J Neurosci 27:13117-13129 (Pubitemid 350220488)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.48
, pp. 13117-13129
-
-
Garvalov, B.K.1
Flynn, K.C.2
Neukirchen, D.3
Meyn, L.4
Teusch, N.5
Wu, X.6
Brakebusch, C.7
Bamburg, J.R.8
Bradke, F.9
-
72
-
-
33749532141
-
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS
-
DOI 10.1523/JNEUROSCI.2158-06.2006
-
Thurnherr T, Benninger Y, Wu X, Chrostek A, Krause SM, Nave KA, Franklin RJ, Brakebusch C, Suter U, Relvas JB (2006) Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. J Neurosci 26:10110-10119 (Pubitemid 44527405)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.40
, pp. 10110-10119
-
-
Thurnherr, T.1
Benninger, Y.2
Wu, X.3
Chrostek, A.4
Krause, S.M.5
Nave, K.-A.6
Franklin, R.J.M.7
Brakebusch, C.8
Suter, U.9
Relvas, J.B.10
-
73
-
-
84880668691
-
Cdc42 promotes host defenses against fatal infection
-
3719566 23690402
-
Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R (2013) Cdc42 promotes host defenses against fatal infection. Infect Immun 81:2714-2723
-
(2013)
Infect Immun
, vol.81
, pp. 2714-2723
-
-
Lee, K.1
Boyd, K.L.2
Parekh, D.V.3
Kehl-Fie, T.E.4
Baldwin, H.S.5
Brakebusch, C.6
Skaar, E.P.7
Boothby, M.8
Zent, R.9
-
74
-
-
33750493895
-
Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts
-
DOI 10.1091/mbc.E06-05-0466
-
Yang L, Wang L, Zheng Y (2006) Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. Mol Biol Cell 17:4675-4685 (Pubitemid 44665738)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.11
, pp. 4675-4685
-
-
Yang, L.1
Wang, L.2
Zheng, Y.3
-
75
-
-
26244449496
-
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells
-
DOI 10.1091/mbc.E05-01-0061
-
Czuchra A, Wu X, Meyer H, van Hengel J, Schroeder T, Geffers R, Rottner K, Brakebusch C (2005) Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Mol Biol Cell 16:4473-4484 (Pubitemid 41416434)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.10
, pp. 4473-4484
-
-
Czuchra, A.1
Wu, X.2
Meyer, H.3
Van Hengel, J.4
Schroeder, T.5
Geffers, R.6
Rottner, K.7
Brakebusch, C.8
-
76
-
-
0035912228
-
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10
-
DOI 10.1038/35073608
-
Chiang SH, Baumann CA, Kanzaki M, Thurmond DC, Watson RT, Neudauer CL, Macara IG, Pessin JE, Saltiel AR (2001) Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature 410:944-948 (Pubitemid 32335841)
-
(2001)
Nature
, vol.410
, Issue.6831
, pp. 944-948
-
-
Chiang, S.-H.1
Baumann, C.A.2
Kanzaki, M.3
Thurmond, D.C.4
Watson, R.T.5
Neudauer, C.L.6
Macara, I.G.7
Pessin, J.E.8
Saltiel, A.R.9
-
77
-
-
33747858041
-
GTP Hydrolysis by the Rho Family GTPase TC10 Promotes Exocytic Vesicle Fusion
-
DOI 10.1016/j.devcel.2006.07.008, PII S1534580706003091
-
Kawase K, Nakamura T, Takaya A, Aoki K, Namikawa K, Kiyama H, Inagaki S, Takemoto H, Saltiel AR, Matsuda M (2006) GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion. Dev Cell 11:411-421 (Pubitemid 44283945)
-
(2006)
Developmental Cell
, vol.11
, Issue.3
, pp. 411-421
-
-
Kawase, K.1
Nakamura, T.2
Takaya, A.3
Aoki, K.4
Namikawa, K.5
Kiyama, H.6
Inagaki, S.7
Takemoto, H.8
Saltiel, A.R.9
Matsuda, M.10
-
78
-
-
0037242248
-
Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth
-
DOI 10.1242/jcs.00208
-
Abe T, Kato M, Miki H, Takenawa T, Endo T (2003) Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth. J Cell Sci 116:155-168 (Pubitemid 36113974)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.1
, pp. 155-168
-
-
Abe, T.1
Kato, M.2
Miki, H.3
Takenawa, T.4
Endo, T.5
-
80
-
-
84875580811
-
At the leading edge of three-dimensional cell migration
-
23378019
-
Petrie RJ, Yamada KM (2012) At the leading edge of three-dimensional cell migration. J Cell Sci 125:5917-5926
-
(2012)
J Cell Sci
, vol.125
, pp. 5917-5926
-
-
Petrie, R.J.1
Yamada, K.M.2
-
81
-
-
19644375086
-
Non-equilibration of hydrostatic pressure in blebbing cells
-
DOI 10.1038/nature03550
-
Charras GT, Yarrow JC, Horton MA, Mahadevan L, Mitchison TJ (2005) Non-equilibration of hydrostatic pressure in blebbing cells. Nature 435:365-369 (Pubitemid 40745547)
-
(2005)
Nature
, vol.435
, Issue.7040
, pp. 365-369
-
-
Charras, G.T.1
Yarrow, J.C.2
Horton, M.A.3
Mahadevan, L.4
Mitchison, T.J.5
-
82
-
-
80054031825
-
Degrading devices: Invadosomes in proteolytic cell invasion
-
21801014
-
Linder S, Wiesner C, Himmel M (2011) Degrading devices: invadosomes in proteolytic cell invasion. Annu Rev Cell Dev Biol 27:185-211
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 185-211
-
-
Linder, S.1
Wiesner, C.2
Himmel, M.3
-
83
-
-
58149332179
-
Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization
-
2586586 18775961
-
Provenzano PP, Inman DR, Eliceiri KW, Trier SM, Keely PJ (2008) Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization. Biophys J 95:5374-5384
-
(2008)
Biophys J
, vol.95
, pp. 5374-5384
-
-
Provenzano, P.P.1
Inman, D.R.2
Eliceiri, K.W.3
Trier, S.M.4
Keely, P.J.5
-
84
-
-
33846293595
-
Probing the microenvironment of mammary tumors using multiphoton microscopy
-
DOI 10.1007/s10911-006-9021-5
-
Sidani M, Wyckoff J, Xue C, Segall JE, Condeelis J (2006) Probing the microenvironment of mammary tumors using multiphoton microscopy. J Mammary Gland Biol Neoplasia 11:151-163 (Pubitemid 46111262)
-
(2006)
Journal of Mammary Gland Biology and Neoplasia
, vol.11
, Issue.2
, pp. 151-163
-
-
Sidani, M.1
Wyckoff, J.2
Xue, C.3
Segall, J.E.4
Condeelis, J.5
-
85
-
-
84867887350
-
Deconstructing the third dimension: How 3D culture microenvironments alter cellular cues
-
3434846 22797912
-
Baker BM, Chen CS (2012) Deconstructing the third dimension: how 3D culture microenvironments alter cellular cues. J Cell Sci 125:3015-3024
-
(2012)
J Cell Sci
, vol.125
, pp. 3015-3024
-
-
Baker, B.M.1
Chen, C.S.2
-
86
-
-
70449526719
-
Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
-
2773241 19838175
-
Giampieri S, Manning C, Hooper S, Jones L, Hill CS, Sahai E (2009) Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol 11:1287-1296
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1287-1296
-
-
Giampieri, S.1
Manning, C.2
Hooper, S.3
Jones, L.4
Hill, C.S.5
Sahai, E.6
-
87
-
-
46749126941
-
Fibroblast mechanics in three-dimensional collagen matrices
-
DOI 10.1016/j.jbmt.2008.03.005, PII S1360859208000636
-
Grinnell F (2008) Fibroblast mechanics in three-dimensional collagen matrices. J Bodyw Mov Ther 12:191-193 (Pubitemid 351952483)
-
(2008)
Journal of Bodywork and Movement Therapies
, vol.12
, Issue.3
, pp. 191-193
-
-
Grinnell, F.1
-
88
-
-
54549088877
-
Rac activation and inactivation control plasticity of tumor cell movement
-
18984162
-
Sanz-Moreno V, Gadea G, Ahn J, Paterson H, Marra P, Pinner S, Sahai E, Marshall CJ (2008) Rac activation and inactivation control plasticity of tumor cell movement. Cell 135:510-523
-
(2008)
Cell
, vol.135
, pp. 510-523
-
-
Sanz-Moreno, V.1
Gadea, G.2
Ahn, J.3
Paterson, H.4
Marra, P.5
Pinner, S.6
Sahai, E.7
Marshall, C.J.8
-
89
-
-
77956915812
-
Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics
-
20826462
-
Lee HH, Tien SC, Jou TS, Chang YC, Jhong JG, Chang ZF (2010) Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics. J Cell Sci 123:3368-3377
-
(2010)
J Cell Sci
, vol.123
, pp. 3368-3377
-
-
Lee, H.H.1
Tien, S.C.2
Jou, T.S.3
Chang, Y.C.4
Jhong, J.G.5
Chang, Z.F.6
-
90
-
-
0035943401
-
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCζ
-
DOI 10.1016/S0092-8674(01)00471-8
-
Etienne-Manneville S, Hall A (2001) Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. Cell 106:489-498 (Pubitemid 32786992)
-
(2001)
Cell
, vol.106
, Issue.4
, pp. 489-498
-
-
Etienne-Manneville, S.1
Hall, A.2
-
91
-
-
0344305784
-
Cell Migration: Integrating Signals from Front to Back
-
DOI 10.1126/science.1092053
-
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR (2003) Cell migration: integrating signals from front to back. Science 302:1704-1709 (Pubitemid 37505725)
-
(2003)
Science
, vol.302
, Issue.5651
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
Firtel, R.A.4
Ginsberg, M.H.5
Borisy, G.6
Parsons, J.T.7
Horwitz, A.R.8
-
92
-
-
78649330831
-
Mesenchymal mode of migration participates in pulmonary metastasis of mouse osteosarcoma LM8
-
20872237
-
Yui Y, Itoh K, Yoshioka K, Naka N, Watanabe M, Hiraumi Y, Matsubara H, Watanabe K, Sano K, Nakahata T, Adachi S (2010) Mesenchymal mode of migration participates in pulmonary metastasis of mouse osteosarcoma LM8. Clin Exp Metastasis 27:619-630
-
(2010)
Clin Exp Metastasis
, vol.27
, pp. 619-630
-
-
Yui, Y.1
Itoh, K.2
Yoshioka, K.3
Naka, N.4
Watanabe, M.5
Hiraumi, Y.6
Matsubara, H.7
Watanabe, K.8
Sano, K.9
Nakahata, T.10
Adachi, S.11
-
93
-
-
84861851966
-
FMNL2 drives actin-based protrusion and migration downstream of Cdc42
-
3765947 22608513
-
Block J, Breitsprecher D, Kuhn S, Winterhoff M, Kage F, Geffers R, Duwe P, Rohn JL, Baum B, Brakebusch C, Geyer M, Stradal TE, Faix J, Rottner K (2012) FMNL2 drives actin-based protrusion and migration downstream of Cdc42. Curr Biol 22:1005-1012
-
(2012)
Curr Biol
, vol.22
, pp. 1005-1012
-
-
Block, J.1
Breitsprecher, D.2
Kuhn, S.3
Winterhoff, M.4
Kage, F.5
Geffers, R.6
Duwe, P.7
Rohn, J.L.8
Baum, B.9
Brakebusch, C.10
Geyer, M.11
Stradal, T.E.12
Faix, J.13
Rottner, K.14
-
94
-
-
0035157971
-
Activation of RhoA and ROCK are essential for detachment of migrating leukocytes
-
Alblas J, Ulfman L, Hordijk P, Koenderman L (2001) Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes. Mol Biol Cell 12:2137-2145 (Pubitemid 33049705)
-
(2001)
Molecular Biology of the Cell
, vol.12
, Issue.7
, pp. 2137-2145
-
-
Alblas, J.1
Ulfman, L.2
Hordijk, P.3
Koenderman, L.4
-
95
-
-
24344482090
-
Localized RhoA activation as a requirement for the induction of membrane ruffling
-
DOI 10.1091/mbc.E04-12-1076
-
Kurokawa K, Matsuda M (2005) Localized RhoA activation as a requirement for the induction of membrane ruffling. Mol Biol Cell 16:4294-4303 (Pubitemid 41262897)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.9
, pp. 4294-4303
-
-
Kurokawa, K.1
Matsuda, M.2
-
96
-
-
36849001517
-
Syndecan-1 interaction with the LG4/5 domain in laminin-332 is essential for keratinocyte migration
-
DOI 10.1002/jcp.21184
-
Bachy S, Letourneur F, Rousselle P (2008) Syndecan-1 interaction with the LG4/5 domain in laminin-332 is essential for keratinocyte migration. J Cell Physiol 214:238-249 (Pubitemid 350220078)
-
(2008)
Journal of Cellular Physiology
, vol.214
, Issue.1
, pp. 238-249
-
-
Bachy, S.1
Letourneur, F.2
Rousselle, P.3
-
97
-
-
74049088595
-
MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling
-
2822729 20152179
-
Gonzalo P, Guadamillas MC, Hernandez-Riquer MV, Pollan A, Grande-Garcia A, Bartolome RA, Vasanji A, Ambrogio C, Chiarle R, Teixido J, Risteli J, Apte SS, del Pozo MA, Arroyo AG (2010) MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling. Dev Cell 18:77-89
-
(2010)
Dev Cell
, vol.18
, pp. 77-89
-
-
Gonzalo, P.1
Guadamillas, M.C.2
Hernandez-Riquer, M.V.3
Pollan, A.4
Grande-Garcia, A.5
Bartolome, R.A.6
Vasanji, A.7
Ambrogio, C.8
Chiarle, R.9
Teixido, J.10
Risteli, J.11
Apte, S.S.12
Del Pozo, M.A.13
Arroyo, A.G.14
-
98
-
-
0032496326
-
Role of rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change
-
DOI 10.1126/science.280.5365.898
-
Kheradmand F, Werner E, Tremble P, Symons M, Werb Z (1998) Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change. Science 280:898-902 (Pubitemid 28215599)
-
(1998)
Science
, vol.280
, Issue.5365
, pp. 898-902
-
-
Kheradmand, F.1
Werner, E.2
Tremble, P.3
Symons, M.4
Werb, Z.5
-
99
-
-
0345643514
-
Regulation of matrix metalloproteinase expression in tumor invasion
-
Westermarck J, Kahari VM (1999) Regulation of matrix metalloproteinase expression in tumor invasion. Faseb J 13:781-792 (Pubitemid 29220691)
-
(1999)
FASEB Journal
, vol.13
, Issue.8
, pp. 781-792
-
-
Westermarck, J.1
Kahari, V.-M.2
-
100
-
-
84862956461
-
Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression
-
3256912 22128168
-
Yamagata K, Li X, Ikegaki S, Oneyama C, Okada M, Nishita M, Minami Y (2012) Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression. J Biol Chem 287:1588-1599
-
(2012)
J Biol Chem
, vol.287
, pp. 1588-1599
-
-
Yamagata, K.1
Li, X.2
Ikegaki, S.3
Oneyama, C.4
Okada, M.5
Nishita, M.6
Minami, Y.7
-
101
-
-
84867083414
-
The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion
-
22249252
-
Jeong KJ, Park SY, Cho KH, Sohn JS, Lee J, Kim YK, Kang J, Park CG, Han JW, Lee HY (2012) The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion. Oncogene 31:4279-4289
-
(2012)
Oncogene
, vol.31
, pp. 4279-4289
-
-
Jeong, K.J.1
Park, S.Y.2
Cho, K.H.3
Sohn, J.S.4
Lee, J.5
Kim, Y.K.6
Kang, J.7
Park, C.G.8
Han, J.W.9
Lee, H.Y.10
-
102
-
-
0034194578
-
A critical step in metastasis: In vivo analysis of intravasation at the primary tumor
-
Wyckoff JB, Jones JG, Condeelis JS, Segall JE (2000) A critical step in metastasis: in vivo analysis of intravasation at the primary tumor. Cancer Res 60:2504-2511 (Pubitemid 30262445)
-
(2000)
Cancer Research
, vol.60
, Issue.9
, pp. 2504-2511
-
-
Wyckoff, J.B.1
Jones, J.G.2
Condeelis, J.S.3
Segall, J.E.4
-
103
-
-
57049125131
-
A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis
-
2637261 19081071
-
Philippar U, Roussos ET, Oser M, Yamaguchi H, Kim HD, Giampieri S, Wang Y, Goswami S, Wyckoff JB, Lauffenburger DA, Sahai E, Condeelis JS, Gertler FB (2008) A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis. Dev Cell 15:813-828
-
(2008)
Dev Cell
, vol.15
, pp. 813-828
-
-
Philippar, U.1
Roussos, E.T.2
Oser, M.3
Yamaguchi, H.4
Kim, H.D.5
Giampieri, S.6
Wang, Y.7
Goswami, S.8
Wyckoff, J.B.9
Lauffenburger, D.A.10
Sahai, E.11
Condeelis, J.S.12
Gertler, F.B.13
-
104
-
-
26844505891
-
Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy
-
1159039 15910685
-
Sahai E, Wyckoff J, Philippar U, Segall JE, Gertler F, Condeelis J (2005) Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy. BMC Biotechnol 5:14
-
(2005)
BMC Biotechnol
, vol.5
, pp. 14
-
-
Sahai, E.1
Wyckoff, J.2
Philippar, U.3
Segall, J.E.4
Gertler, F.5
Condeelis, J.6
-
105
-
-
31544468879
-
Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis
-
DOI 10.1158/0008-5472.CAN-05-1242
-
Xue C, Wyckoff J, Liang F, Sidani M, Violini S, Tsai KL, Zhang ZY, Sahai E, Condeelis J, Segall JE (2006) Epidermal growth factor receptor overexpression results in increased tumor cell motility in vivo coordinately with enhanced intravasation and metastasis. Cancer Res 66:192-197 (Pubitemid 43166025)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 192-197
-
-
Xue, C.1
Wyckoff, J.2
Liang, F.3
Sidani, M.4
Violini, S.5
Tsai, K.-L.6
Zhang, Z.-Y.7
Sahai, E.8
Condeelis, J.9
Segall, J.E.10
-
106
-
-
45349096499
-
Cell motility through plasma membrane blebbing
-
DOI 10.1083/jcb.200802081
-
Fackler OT, Grosse R (2008) Cell motility through plasma membrane blebbing. J Cell Biol 181:879-884 (Pubitemid 351846821)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.6
, pp. 879-884
-
-
Fackler, O.T.1
Grosse, R.2
-
107
-
-
0029870635
-
Protrusive activity quantitatively determines the rate and direction of cell locomotion
-
DOI 10.1002/(SICI)1097-0169(1996)33:4<241::AID-CM1>3.0.CO;2-C
-
Keller HU, Bebie H (1996) Protrusive activity quantitatively determines the rate and direction of cell locomotion. Cell Motil Cytoskelet 33:241-251 (Pubitemid 26108415)
-
(1996)
Cell Motility and the Cytoskeleton
, vol.33
, Issue.4
, pp. 241-251
-
-
Keller, H.U.1
Bebie, H.2
-
108
-
-
33750320965
-
Dissection of amoeboid movement into two mechanically distinct modes
-
DOI 10.1242/jcs.03152
-
Yoshida K, Soldati T (2006) Dissection of amoeboid movement into two mechanically distinct modes. J Cell Sci 119:3833-3844 (Pubitemid 44614435)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.18
, pp. 3833-3844
-
-
Yoshida, K.1
Soldati, T.2
-
109
-
-
75749146306
-
Plasticity of cell migration: A multiscale tuning model
-
2812848 19951899
-
Friedl P, Wolf K (2010) Plasticity of cell migration: a multiscale tuning model. J Cell Biol 188:11-19
-
(2010)
J Cell Biol
, vol.188
, pp. 11-19
-
-
Friedl, P.1
Wolf, K.2
-
110
-
-
0042354574
-
Differing modes for tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
-
DOI 10.1038/ncb1019
-
Sahai E, Marshall CJ (2003) Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 5:711-719 (Pubitemid 36986778)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.8
, pp. 711-719
-
-
Sahai, E.1
Marshall, C.J.2
-
111
-
-
43049085527
-
Rapid leukocyte migration by integrin-independent flowing and squeezing
-
DOI 10.1038/nature06887, PII NATURE06887
-
Lammermann T, Bader BL, Monkley SJ, Worbs T, Wedlich-Soldner R, Hirsch K, Keller M, Forster R, Critchley DR, Fassler R, Sixt M (2008) Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature 453:51-55 (Pubitemid 351630331)
-
(2008)
Nature
, vol.453
, Issue.7191
, pp. 51-55
-
-
Lammermann, T.1
Bader, B.L.2
Monkley, S.J.3
Worbs, T.4
Wedlich-Soldner, R.5
Hirsch, K.6
Keller, M.7
Forster, R.8
Critchley, D.R.9
Fassler, R.10
Sixt, M.11
-
112
-
-
38849185196
-
PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
-
DOI 10.1038/ncb1675, PII NCB1675
-
Pinner S, Sahai E (2008) PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nat Cell Biol 10:127-137 (Pubitemid 351194042)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.2
, pp. 127-137
-
-
Pinner, S.1
Sahai, E.2
-
113
-
-
33947666586
-
Dia-Interacting Protein Modulates Formin-Mediated Actin Assembly at the Cell Cortex
-
DOI 10.1016/j.cub.2007.03.024, PII S0960982207011268
-
Eisenmann KM, Harris ES, Kitchen SM, Holman HA, Higgs HN, Alberts AS (2007) Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex. Curr Biol 17:579-591 (Pubitemid 46497803)
-
(2007)
Current Biology
, vol.17
, Issue.7
, pp. 579-591
-
-
Eisenmann, K.M.1
Harris, E.S.2
Kitchen, S.M.3
Holman, H.A.4
Higgs, H.N.5
Alberts, A.S.6
-
114
-
-
51049114294
-
Mechanical forces induced by the transendothelial migration of human neutrophils
-
2479581 18390614
-
Rabodzey A, Alcaide P, Luscinskas FW, Ladoux B (2008) Mechanical forces induced by the transendothelial migration of human neutrophils. Biophys J 95:1428-1438
-
(2008)
Biophys J
, vol.95
, pp. 1428-1438
-
-
Rabodzey, A.1
Alcaide, P.2
Luscinskas, F.W.3
Ladoux, B.4
-
115
-
-
65249155429
-
Protease-dependent versus -independent cancer cell invasion programs: Three-dimensional amoeboid movement revisited
-
2700505 19332889
-
Sabeh F, Shimizu-Hirota R, Weiss SJ (2009) Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J Cell Biol 185:11-19
-
(2009)
J Cell Biol
, vol.185
, pp. 11-19
-
-
Sabeh, F.1
Shimizu-Hirota, R.2
Weiss, S.J.3
-
116
-
-
34547569807
-
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
-
DOI 10.1038/ncb1616, PII NCB1616
-
Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P (2007) Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol 9:893-904 (Pubitemid 47190444)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.8
, pp. 893-904
-
-
Wolf, K.1
Wu, Y.I.2
Liu, Y.3
Geiger, J.4
Tam, E.5
Overall, C.6
Stack, M.S.7
Friedl, P.8
-
117
-
-
53249143863
-
DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells
-
18835169
-
Gadea G, Sanz-Moreno V, Self A, Godi A, Marshall CJ (2008) DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells. Curr Biol 18:1456-1465
-
(2008)
Curr Biol
, vol.18
, pp. 1456-1465
-
-
Gadea, G.1
Sanz-Moreno, V.2
Self, A.3
Godi, A.4
Marshall, C.J.5
-
118
-
-
79953156598
-
An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells
-
21444753
-
Lorentzen A, Bamber J, Sadok A, Elson-Schwab I, Marshall CJ (2011) An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells. J Cell Sci 124:1256-1267
-
(2011)
J Cell Sci
, vol.124
, pp. 1256-1267
-
-
Lorentzen, A.1
Bamber, J.2
Sadok, A.3
Elson-Schwab, I.4
Marshall, C.J.5
-
120
-
-
0028866016
-
Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro
-
7553628
-
Friedl P, Noble PB, Walton PA, Laird DW, Chauvin PJ, Tabah RJ, Black M, Zanker KS (1995) Migration of coordinated cell clusters in mesenchymal and epithelial cancer explants in vitro. Cancer Res 55:4557-4560
-
(1995)
Cancer Res
, vol.55
, pp. 4557-4560
-
-
Friedl, P.1
Noble, P.B.2
Walton, P.A.3
Laird, D.W.4
Chauvin, P.J.5
Tabah, R.J.6
Black, M.7
Zanker, K.S.8
-
121
-
-
67649528138
-
Collective cell migration in morphogenesis, regeneration and cancer
-
19546857
-
Friedl P, Gilmour D (2009) Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 10:445-457
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 445-457
-
-
Friedl, P.1
Gilmour, D.2
-
122
-
-
67749129117
-
The group migration of Dictyostelium cells is regulated by extracellular chemoattractant degradation
-
2710833 19477920
-
Garcia GL, Rericha EC, Heger CD, Goldsmith PK, Parent CA (2009) The group migration of Dictyostelium cells is regulated by extracellular chemoattractant degradation. Mol Biol Cell 20:3295-3304
-
(2009)
Mol Biol Cell
, vol.20
, pp. 3295-3304
-
-
Garcia, G.L.1
Rericha, E.C.2
Heger, C.D.3
Goldsmith, P.K.4
Parent, C.A.5
-
123
-
-
72849112793
-
Cadherin-2 controls directional chain migration of cerebellar granule neurons
-
2766073 19901980
-
Rieger S, Senghaas N, Walch A, Koster RW (2009) Cadherin-2 controls directional chain migration of cerebellar granule neurons. PLoS Biol 7:e1000240
-
(2009)
PLoS Biol
, vol.7
, pp. 1000240
-
-
Rieger, S.1
Senghaas, N.2
Walch, A.3
Koster, R.W.4
-
124
-
-
77956459044
-
Rac and Rho GTPases in cancer cell motility control
-
2941746 20822528
-
Parri M, Chiarugi P (2010) Rac and Rho GTPases in cancer cell motility control. Cell Commun Signal 8:23
-
(2010)
Cell Commun Signal
, vol.8
, pp. 23
-
-
Parri, M.1
Chiarugi, P.2
-
125
-
-
41649121862
-
Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis
-
DOI 10.1016/j.devcel.2008.03.003, PII S1534580708001111
-
Ewald AJ, Brenot A, Duong M, Chan BS, Werb Z (2008) Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev Cell 14:570-581 (Pubitemid 351479940)
-
(2008)
Developmental Cell
, vol.14
, Issue.4
, pp. 570-581
-
-
Ewald, A.J.1
Brenot, A.2
Duong, M.3
Chan, B.S.4
Werb, Z.5
-
126
-
-
77957244401
-
Cellular mechanisms regulating epithelial morphogenesis and cancer invasion
-
2948645 20832275
-
Gray RS, Cheung KJ, Ewald AJ (2010) Cellular mechanisms regulating epithelial morphogenesis and cancer invasion. Curr Opin Cell Biol 22:640-650
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 640-650
-
-
Gray, R.S.1
Cheung, K.J.2
Ewald, A.J.3
-
127
-
-
0033398793
-
Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes
-
Scholl FG, Gamallo C, Vilaro S, Quintanilla M (1999) Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes. J Cell Sci 112(Pt 24):4601-4613 (Pubitemid 30034809)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.24
, pp. 4601-4613
-
-
Scholl, F.G.1
Gamallo, C.2
Vilaro, S.3
Quintanilla, M.4
-
128
-
-
33645758275
-
Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton
-
16616332
-
Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G (2006) Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 9:261-272
-
(2006)
Cancer Cell
, vol.9
, pp. 261-272
-
-
Wicki, A.1
Lehembre, F.2
Wick, N.3
Hantusch, B.4
Kerjaschki, D.5
Christofori, G.6
-
129
-
-
78650512223
-
Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6
-
3018349 21170030
-
Hidalgo-Carcedo C, Hooper S, Chaudhry SI, Williamson P, Harrington K, Leitinger B, Sahai E (2011) Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6. Nat Cell Biol 13:49-58
-
(2011)
Nat Cell Biol
, vol.13
, pp. 49-58
-
-
Hidalgo-Carcedo, C.1
Hooper, S.2
Chaudhry, S.I.3
Williamson, P.4
Harrington, K.5
Leitinger, B.6
Sahai, E.7
-
130
-
-
79955623603
-
Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis
-
21516109
-
Levayer R, Pelissier-Monier A, Lecuit T (2011) Spatial regulation of Dia and Myosin-II by RhoGEF2 controls initiation of E-cadherin endocytosis during epithelial morphogenesis. Nat Cell Biol 13:529-540
-
(2011)
Nat Cell Biol
, vol.13
, pp. 529-540
-
-
Levayer, R.1
Pelissier-Monier, A.2
Lecuit, T.3
-
131
-
-
41549155540
-
Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor
-
DOI 10.1083/jcb.200708137
-
Shintani Y, Fukumoto Y, Chaika N, Svoboda R, Wheelock MJ, Johnson KR (2008) Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1. J Cell Biol 180:1277-1289 (Pubitemid 351468480)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.6
, pp. 1277-1289
-
-
Shintani, Y.1
Fukumoto, Y.2
Chaika, N.3
Svoboda, R.4
Wheelock, M.J.5
Johnson, K.R.6
-
132
-
-
77954926645
-
Collective chemotaxis requires contact-dependent cell polarity
-
2913244 20643349
-
Theveneau E, Marchant L, Kuriyama S, Gull M, Moepps B, Parsons M, Mayor R (2010) Collective chemotaxis requires contact-dependent cell polarity. Dev Cell 19:39-53
-
(2010)
Dev Cell
, vol.19
, pp. 39-53
-
-
Theveneau, E.1
Marchant, L.2
Kuriyama, S.3
Gull, M.4
Moepps, B.5
Parsons, M.6
Mayor, R.7
-
133
-
-
79952046499
-
Integrating chemotaxis and contact-inhibition during collective cell migration: Small GTPases at work
-
3116595 21686264
-
Theveneau E, Mayor R (2010) Integrating chemotaxis and contact-inhibition during collective cell migration: small GTPases at work. Small GTPases 1:113-117
-
(2010)
Small GTPases
, vol.1
, pp. 113-117
-
-
Theveneau, E.1
Mayor, R.2
-
134
-
-
36049049520
-
Collective migration of an epithelial monolayer in response to a model wound
-
DOI 10.1073/pnas.0705062104
-
Poujade M, Grasland-Mongrain E, Hertzog A, Jouanneau J, Chavrier P, Ladoux B, Buguin A, Silberzan P (2007) Collective migration of an epithelial monolayer in response to a model wound. Proc Natl Acad Sci USA 104:15988-15993 (Pubitemid 350099346)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.41
, pp. 15988-15993
-
-
Poujade, M.1
Grasland-Mongrain, E.2
Hertzog, A.3
Jouanneau, J.4
Chavrier, P.5
Ladoux, B.6
Buguin, A.7
Silberzan, P.8
-
135
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
DOI 10.1038/ncb1658, PII NCB1658
-
Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E (2007) Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 9:1392-1400 (Pubitemid 350201752)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.12
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
Sahai, E.7
-
136
-
-
80051587832
-
ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma
-
21840487
-
Sanz-Moreno V, Gaggioli C, Yeo M, Albrengues J, Wallberg F, Viros A, Hooper S, Mitter R, Feral CC, Cook M, Larkin J, Marais R, Meneguzzi G, Sahai E, Marshall CJ (2011) ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma. Cancer Cell 20:229-245
-
(2011)
Cancer Cell
, vol.20
, pp. 229-245
-
-
Sanz-Moreno, V.1
Gaggioli, C.2
Yeo, M.3
Albrengues, J.4
Wallberg, F.5
Viros, A.6
Hooper, S.7
Mitter, R.8
Feral, C.C.9
Cook, M.10
Larkin, J.11
Marais, R.12
Meneguzzi, G.13
Sahai, E.14
Marshall, C.J.15
-
137
-
-
0015340401
-
Mode of cell migration to the superficial layers of fetal monkey neocortex
-
4624784
-
Rakic P (1972) Mode of cell migration to the superficial layers of fetal monkey neocortex. J Comp Neurol 145:61-83
-
(1972)
J Comp Neurol
, vol.145
, pp. 61-83
-
-
Rakic, P.1
-
138
-
-
77955956961
-
Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking
-
20797536
-
Kawauchi T, Sekine K, Shikanai M, Chihama K, Tomita K, Kubo K, Nakajima K, Nabeshima Y, Hoshino M (2010) Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-cadherin trafficking. Neuron 67:588-602
-
(2010)
Neuron
, vol.67
, pp. 588-602
-
-
Kawauchi, T.1
Sekine, K.2
Shikanai, M.3
Chihama, K.4
Tomita, K.5
Kubo, K.6
Nakajima, K.7
Nabeshima, Y.8
Hoshino, M.9
-
139
-
-
84860154681
-
N-cadherin regulates radial glial fiber-dependent migration of cortical locomoting neurons
-
3187899 21980571
-
Shikanai M, Nakajima K, Kawauchi T (2011) N-cadherin regulates radial glial fiber-dependent migration of cortical locomoting neurons. Commun Integr Biol 4:326-330
-
(2011)
Commun Integr Biol
, vol.4
, pp. 326-330
-
-
Shikanai, M.1
Nakajima, K.2
Kawauchi, T.3
-
140
-
-
67651005404
-
EMT: When epithelial cells decide to become mesenchymal-like cells
-
2689122 19487817
-
Kalluri R (2009) EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 119:1417-1419
-
(2009)
J Clin Invest
, vol.119
, pp. 1417-1419
-
-
Kalluri, R.1
-
141
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
DOI 10.1158/0008-5472.CAN-07-5682
-
Spaderna S, Schmalhofer O, Wahlbuhl M, Dimmler A, Bauer K, Sultan A, Hlubek F, Jung A, Strand D, Eger A, Kirchner T, Behrens J, Brabletz T (2008) The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res 68:537-544 (Pubitemid 351380082)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
Dimmler, A.4
Bauer, K.5
Sultan, A.6
Hlubek, F.7
Jung, A.8
Strand, D.9
Eger, A.10
Kirchner, T.11
Behrens, J.12
Brabletz, T.13
-
142
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
DOI 10.1016/j.cell.2004.06.006, PII S0092867404005768
-
Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117:927-939 (Pubitemid 38798858)
-
(2004)
Cell
, vol.117
, Issue.7
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
143
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
19945376
-
Thiery JP, Acloque H, Huang RY, Nieto MA (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139:871-890
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
144
-
-
21844432918
-
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
-
DOI 10.1038/nature03688
-
Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA, Werb Z, Bissell MJ (2005) Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature 436:123-127 (Pubitemid 40966197)
-
(2005)
Nature
, vol.436
, Issue.7047
, pp. 123-127
-
-
Radisky, D.C.1
Levy, D.D.2
Littlepage, L.E.3
Liu, H.4
Nelson, C.M.5
Fata, J.E.6
Leake, D.7
Godden, E.L.8
Albertson, D.G.9
Nieto, M.A.10
Werb, Z.11
Bissell, M.J.12
-
145
-
-
0030698191
-
Inhibition of invasion of epithelial cells by Tiam1-Rac signaling
-
DOI 10.1126/science.278.5342.1464
-
Hordijk PL, ten Klooster JP, van der Kammen RA, Michiels F, Oomen LC, Collard JG (1997) Inhibition of invasion of epithelial cells by Tiam1-Rac signaling. Science 278:1464-1466 (Pubitemid 27509819)
-
(1997)
Science
, vol.278
, Issue.5342
, pp. 1464-1466
-
-
Hordijk, P.L.1
Ten Klooster, J.P.2
Van Der Kammen, R.A.3
Michiels, F.4
Oomen, L.C.J.M.5
Collard, J.G.6
-
146
-
-
3142674246
-
The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions
-
DOI 10.1074/jbc.M401192200
-
Malliri A, van Es S, Huveneers S, Collard JG (2004) The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions. J Biol Chem 279:30092-30098 (Pubitemid 38937931)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.29
, pp. 30092-30098
-
-
Malliri, A.1
Van Es, S.2
Huveneers, S.3
Collard, J.G.4
-
147
-
-
84861882390
-
The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility
-
22328516
-
Ahn J, Sanz-Moreno V, Marshall CJ (2012) The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility. J Cell Sci 125:1814-1826
-
(2012)
J Cell Sci
, vol.125
, pp. 1814-1826
-
-
Ahn, J.1
Sanz-Moreno, V.2
Marshall, C.J.3
-
148
-
-
62449186707
-
EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style
-
19244130
-
Parri M, Taddei ML, Bianchini F, Calorini L, Chiarugi P (2009) EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style. Cancer Res 69:2072-2081
-
(2009)
Cancer Res
, vol.69
, pp. 2072-2081
-
-
Parri, M.1
Taddei, M.L.2
Bianchini, F.3
Calorini, L.4
Chiarugi, P.5
-
149
-
-
64049095782
-
Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates
-
19234490
-
Yamazaki D, Kurisu S, Takenawa T (2009) Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates. Oncogene 28:1570-1583
-
(2009)
Oncogene
, vol.28
, pp. 1570-1583
-
-
Yamazaki, D.1
Kurisu, S.2
Takenawa, T.3
-
150
-
-
46149125934
-
Endocytic Trafficking of Rac Is Required for the Spatial Restriction of Signaling in Cell Migration
-
DOI 10.1016/j.cell.2008.05.034, PII S009286740800696X
-
Palamidessi A, Frittoli E, Garre M, Faretta M, Mione M, Testa I, Diaspro A, Lanzetti L, Scita G, Di Fiore PP (2008) Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration. Cell 134:135-147 (Pubitemid 351905741)
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 135-147
-
-
Palamidessi, A.1
Frittoli, E.2
Garre, M.3
Faretta, M.4
Mione, M.5
Testa, I.6
Diaspro, A.7
Lanzetti, L.8
Scita, G.9
Di Fiore, P.P.10
-
151
-
-
33846014269
-
Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility
-
DOI 10.1083/jcb.200605135
-
Sahai E, Garcia-Medina R, Pouyssegur J, Vial E (2007) Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility. J Cell Biol 176:35-42 (Pubitemid 46041678)
-
(2007)
Journal of Cell Biology
, vol.176
, Issue.1
, pp. 35-42
-
-
Sahai, E.1
Garcia-Medina, R.2
Pouyssegur, J.3
Vial, E.4
-
152
-
-
84855357301
-
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation
-
3252583 22117219
-
Oberoi TK, Dogan T, Hocking JC, Scholz RP, Mooz J, Anderson CL, Karreman C, Meyer zu Heringdorf D, Schmidt G, Ruonala M, Namikawa K, Harms GS, Carpy A, Macek B, Koster RW, Rajalingam K (2012) IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. Embo J 31:14-28
-
(2012)
Embo J
, vol.31
, pp. 14-28
-
-
Oberoi, T.K.1
Dogan, T.2
Hocking, J.C.3
Scholz, R.P.4
Mooz, J.5
Anderson, C.L.6
Karreman, C.7
Meyer Zu Heringdorf, D.8
Schmidt, G.9
Ruonala, M.10
Namikawa, K.11
Harms, G.S.12
Carpy, A.13
Macek, B.14
Koster, R.W.15
Rajalingam, K.16
-
153
-
-
84861464004
-
IAPs as E3 ligases of Rac1: Shaping the move
-
3408978 22790203
-
Oberoi-Khanuja TK, Rajalingam K (2012) IAPs as E3 ligases of Rac1: shaping the move. Small GTPases 3:131-136
-
(2012)
Small GTPases
, vol.3
, pp. 131-136
-
-
Oberoi-Khanuja, T.K.1
Rajalingam, K.2
-
154
-
-
72249100428
-
Mutant p53 drives invasion by promoting integrin recycling
-
20064378
-
Muller PA, Caswell PT, Doyle B, Iwanicki MP, Tan EH, Karim S, Lukashchuk N, Gillespie DA, Ludwig RL, Gosselin P, Cromer A, Brugge JS, Sansom OJ, Norman JC, Vousden KH (2009) Mutant p53 drives invasion by promoting integrin recycling. Cell 139:1327-1341
-
(2009)
Cell
, vol.139
, pp. 1327-1341
-
-
Muller, P.A.1
Caswell, P.T.2
Doyle, B.3
Iwanicki, M.P.4
Tan, E.H.5
Karim, S.6
Lukashchuk, N.7
Gillespie, D.A.8
Ludwig, R.L.9
Gosselin, P.10
Cromer, A.11
Brugge, J.S.12
Sansom, O.J.13
Norman, J.C.14
Vousden, K.H.15
-
155
-
-
0032751977
-
Stathmin and its phosphoprotein family: General properties, biochemical and functional interaction with tubulin
-
15216892
-
Curmi PA, Gavet O, Charbaut E, Ozon S, Lachkar-Colmerauer S, Manceau V, Siavoshian S, Maucuer A, Sobel A (1999) Stathmin and its phosphoprotein family: general properties, biochemical and functional interaction with tubulin. Cell Struct Funct 24:345-357
-
(1999)
Cell Struct Funct
, vol.24
, pp. 345-357
-
-
Curmi, P.A.1
Gavet, O.2
Charbaut, E.3
Ozon, S.4
Lachkar-Colmerauer, S.5
Manceau, V.6
Siavoshian, S.7
Maucuer, A.8
Sobel, A.9
-
156
-
-
48249132019
-
Stathmin activity influences sarcoma cell shape, motility, and metastatic potential
-
2366875 18305103
-
Belletti B, Nicoloso MS, Schiappacassi M, Berton S, Lovat F, Wolf K, Canzonieri V, D'Andrea S, Zucchetto A, Friedl P, Colombatti A, Baldassarre G (2008) Stathmin activity influences sarcoma cell shape, motility, and metastatic potential. Mol Biol Cell 19:2003-2013
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2003-2013
-
-
Belletti, B.1
Nicoloso, M.S.2
Schiappacassi, M.3
Berton, S.4
Lovat, F.5
Wolf, K.6
Canzonieri, V.7
D'Andrea, S.8
Zucchetto, A.9
Friedl, P.10
Colombatti, A.11
Baldassarre, G.12
-
157
-
-
79961234301
-
Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules
-
3150944 21768358
-
Li N, Jiang P, Du W, Wu Z, Li C, Qiao M, Yang X, Wu M (2011) Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules. Proc Natl Acad Sci USA 108:12851-12856
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 12851-12856
-
-
Li, N.1
Jiang, P.2
Du, W.3
Wu, Z.4
Li, C.5
Qiao, M.6
Yang, X.7
Wu, M.8
-
158
-
-
80054698475
-
Stathmin: A protein with many tasks. New biomarker and potential target in cancer
-
21978024
-
Belletti B, Baldassarre G (2011) Stathmin: a protein with many tasks. New biomarker and potential target in cancer. Expert Opin Ther Targets 15:1249-1266
-
(2011)
Expert Opin Ther Targets
, vol.15
, pp. 1249-1266
-
-
Belletti, B.1
Baldassarre, G.2
-
159
-
-
0037455576
-
Compensation mechanism in tumor cell migration: Mesenchymal-amoeboid transition after blocking of pericellular proteolysis
-
DOI 10.1083/jcb.200209006
-
Wolf K, Mazo I, Leung H, Engelke K, von Andrian UH, Deryugina EI, Strongin AY, Brocker EB, Friedl P (2003) Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol 160:267-277 (Pubitemid 36254960)
-
(2003)
Journal of Cell Biology
, vol.160
, Issue.2
, pp. 267-277
-
-
Wolf, K.1
Mazo, I.2
Leung, H.3
Engelke, K.4
Von Andrian, U.H.5
Deryugina, E.I.6
Strongin, A.Y.7
Brocker, E.-B.8
Friedl, P.9
-
160
-
-
1642282882
-
Prespecification and plasticity: Shifting mechanisms of cell migration
-
DOI 10.1016/j.ceb.2003.11.001, PII S0955067403001571
-
Friedl P (2004) Prespecification and plasticity: shifting mechanisms of cell migration. Curr Opin Cell Biol 16:14-23 (Pubitemid 38368147)
-
(2004)
Current Opinion in Cell Biology
, vol.16
, Issue.1
, pp. 14-23
-
-
Friedl, P.1
-
161
-
-
78649771814
-
Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells
-
3014295 21209796
-
Belgiovine C, Frapolli R, Bonezzi K, Chiodi I, Favero F, Mello-Grand M, Dei Tos AP, Giulotto E, Taraboletti G, D'Incalci M, Mondello C (2010) Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells. PLoS ONE 5:e14154
-
(2010)
PLoS ONE
, vol.5
, pp. 14154
-
-
Belgiovine, C.1
Frapolli, R.2
Bonezzi, K.3
Chiodi, I.4
Favero, F.5
Mello-Grand, M.6
Dei Tos, A.P.7
Giulotto, E.8
Taraboletti, G.9
D'Incalci, M.10
Mondello, C.11
-
162
-
-
84861563951
-
Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion
-
22234932
-
Grise F, Sena S, Bidaud-Meynard A, Baud J, Hiriart JB, Makki K, Dugot-Senant N, Staedel C, Bioulac-Sage P, Zucman-Rossi J, Rosenbaum J, Moreau V (2012) Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion. Hepatology 55:1766-1775
-
(2012)
Hepatology
, vol.55
, pp. 1766-1775
-
-
Grise, F.1
Sena, S.2
Bidaud-Meynard, A.3
Baud, J.4
Hiriart, J.B.5
Makki, K.6
Dugot-Senant, N.7
Staedel, C.8
Bioulac-Sage, P.9
Zucman-Rossi, J.10
Rosenbaum, J.11
Moreau, V.12
-
163
-
-
84859910902
-
Down-regulation of RhoE is associated with progression and poor prognosis in hepatocellular carcinoma
-
22213123
-
Luo H, Dong Z, Zou J, Zeng Q, Wu D, Liu L (2012) Down-regulation of RhoE is associated with progression and poor prognosis in hepatocellular carcinoma. J Surg Oncol 105:699-704
-
(2012)
J Surg Oncol
, vol.105
, pp. 699-704
-
-
Luo, H.1
Dong, Z.2
Zou, J.3
Zeng, Q.4
Wu, D.5
Liu, L.6
-
164
-
-
84855887513
-
Transcriptional up-regulation of RhoE by hypoxia-inducible factor (HIF)-1 promotes epithelial to mesenchymal transition of gastric cancer cells during hypoxia
-
22037464
-
Zhou J, Li K, Gu Y, Feng B, Ren G, Zhang L, Wang Y, Nie Y, Fan D (2011) Transcriptional up-regulation of RhoE by hypoxia-inducible factor (HIF)-1 promotes epithelial to mesenchymal transition of gastric cancer cells during hypoxia. Biochem Biophys Res Commun 415:348-354
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 348-354
-
-
Zhou, J.1
Li, K.2
Gu, Y.3
Feng, B.4
Ren, G.5
Zhang, L.6
Wang, Y.7
Nie, Y.8
Fan, D.9
-
165
-
-
84861450646
-
Nonpolarized signaling reveals two distinct modes of 3D cell migration
-
3341168 22547408
-
Petrie RJ, Gavara N, Chadwick RS, Yamada KM (2012) Nonpolarized signaling reveals two distinct modes of 3D cell migration. J Cell Biol 197:439-455
-
(2012)
J Cell Biol
, vol.197
, pp. 439-455
-
-
Petrie, R.J.1
Gavara, N.2
Chadwick, R.S.3
Yamada, K.M.4
-
166
-
-
81855169565
-
Cancer invasion and the microenvironment: Plasticity and reciprocity
-
22118458
-
Friedl P, Alexander S (2011) Cancer invasion and the microenvironment: plasticity and reciprocity. Cell 147:992-1009
-
(2011)
Cell
, vol.147
, pp. 992-1009
-
-
Friedl, P.1
Alexander, S.2
-
167
-
-
0036532136
-
Collective cell movement in primary melanoma explants: Plasticity of cell-cell interaction, β1-integrin function, and migration strategies
-
Hegerfeldt Y, Tusch M, Brocker EB, Friedl P (2002) Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies. Cancer Res 62:2125-2130 (Pubitemid 34408461)
-
(2002)
Cancer Research
, vol.62
, Issue.7
, pp. 2125-2130
-
-
Hegerfeldt, Y.1
Tusch, M.2
Brocker, E.-B.3
Friedl, P.4
-
168
-
-
4944229701
-
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
-
DOI 10.1158/0008-5472.CAN-04-1449
-
Wyckoff J, Wang W, Lin EY, Wang Y, Pixley F, Stanley ER, Graf T, Pollard JW, Segall J, Condeelis J (2004) A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res 64:7022-7029 (Pubitemid 39331012)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7022-7029
-
-
Wyckoff, J.1
Wang, W.2
Lin, E.Y.3
Wang, Y.4
Pixley, F.5
Stanley, E.R.6
Graf, T.7
Pollard, J.W.8
Segall, J.9
Condeelis, J.10
-
169
-
-
84879660535
-
SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation
-
23512198
-
Zhao J, Mialki RK, Wei J, Coon TA, Zou C, Chen BB, Mallampalli RK, Zhao Y (2013) SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation. Faseb J 27:2611-2619
-
(2013)
Faseb J
, vol.27
, pp. 2611-2619
-
-
Zhao, J.1
Mialki, R.K.2
Wei, J.3
Coon, T.A.4
Zou, C.5
Chen, B.B.6
Mallampalli, R.K.7
Zhao, Y.8
-
170
-
-
0030992838
-
Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine
-
DOI 10.1038/42743
-
Flatau G, Lemichez E, Gauthier M, Chardin P, Paris S, Fiorentini C, Boquet P (1997) Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine. Nature 387:729-733 (Pubitemid 27270616)
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 729-733
-
-
Flatau, G.1
Lemichez, E.2
Gauthier, M.3
Chardin, P.4
Paris, S.5
Florentini, C.6
Boquet, P.7
-
171
-
-
0030610785
-
Gin 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1
-
DOI 10.1038/42735
-
Schmidt G, Sehr P, Wilm M, Selzer J, Mann M, Aktories K (1997) Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1. Nature 387:725-729 (Pubitemid 27270615)
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 725-729
-
-
Schmidt, G.1
Sehr, P.2
Wilm, M.3
Selzer, J.4
Mann, M.5
Aktories, K.6
-
172
-
-
0036070562
-
Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac
-
DOI 10.1128/IAI.70.8.4053-4058.2002
-
Lerm M, Pop M, Fritz G, Aktories K, Schmidt G (2002) Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac. Infect Immun 70:4053-4058 (Pubitemid 34790912)
-
(2002)
Infection and Immunity
, vol.70
, Issue.8
, pp. 4053-4058
-
-
Lerm, M.1
Pop, M.2
Fritz, G.3
Aktories, K.4
Schmidt, G.5
-
173
-
-
14844364701
-
Regulation of the polarity protein Par6 by TGFβ receptors controls epithelial cell plasticity
-
DOI 10.1126/science.1105718
-
Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL (2005) Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 307:1603-1609 (Pubitemid 40354739)
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.-R.4
Zhang, Y.5
Wrana, J.L.6
-
174
-
-
0344758986
-
Regulation of Cell Polarity and Protrusion Formation by Targeting RhoA for Degradation
-
DOI 10.1126/science.1090772
-
Wang HR, Zhang Y, Ozdamar B, Ogunjimi AA, Alexandrova E, Thomsen GH, Wrana JL (2003) Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 302:1775-1779 (Pubitemid 37505743)
-
(2003)
Science
, vol.302
, Issue.5651
, pp. 1775-1779
-
-
Wang, H.-R.1
Zhang, Y.2
Ozdamar, B.3
Ogunjimi, A.A.4
Alexandrova, E.5
Thomsen, G.H.6
Wrana, J.L.7
-
175
-
-
13844257637
-
Ubiquitination of RhoA by Smurf1 promotes neurite outgrowth
-
DOI 10.1016/j.febslet.2004.12.074
-
Bryan B, Cai Y, Wrighton K, Wu G, Feng XH, Liu M (2005) Ubiquitination of RhoA by Smurf1 promotes neurite outgrowth. FEBS Lett 579:1015-1019 (Pubitemid 40248662)
-
(2005)
FEBS Letters
, vol.579
, Issue.5
, pp. 1015-1019
-
-
Bryan, B.1
Cai, Y.2
Wrighton, K.3
Wu, G.4
Feng, X.-H.5
Liu, M.6
-
176
-
-
78649653568
-
Structural assembly of cullin-RING ubiquitin ligase complexes
-
3070871 20880695
-
Zimmerman ES, Schulman BA, Zheng N (2010) Structural assembly of cullin-RING ubiquitin ligase complexes. Curr Opin Struct Biol 20:714-721
-
(2010)
Curr Opin Struct Biol
, vol.20
, pp. 714-721
-
-
Zimmerman, E.S.1
Schulman, B.A.2
Zheng, N.3
-
177
-
-
70349168448
-
Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement
-
19782033
-
Chen Y, Yang Z, Meng M, Zhao Y, Dong N, Yan H, Liu L, Ding M, Peng HB, Shao F (2009) Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. Mol Cell 35:841-855
-
(2009)
Mol Cell
, vol.35
, pp. 841-855
-
-
Chen, Y.1
Yang, Z.2
Meng, M.3
Zhao, Y.4
Dong, N.5
Yan, H.6
Liu, L.7
Ding, M.8
Peng, H.B.9
Shao, F.10
-
178
-
-
84882758542
-
A new mechanism of RhoA ubiquitination and degradation: Roles of SCF E3 ligase and Erk2
-
23871831
-
Wei J, Mialki RK, Dong S, Khoo A, Mallampalli RK, Zhao Y, Zhao J (2013) A new mechanism of RhoA ubiquitination and degradation: roles of SCF E3 ligase and Erk2. Biochim Biophys Acta 1833:2757-2764
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 2757-2764
-
-
Wei, J.1
Mialki, R.K.2
Dong, S.3
Khoo, A.4
Mallampalli, R.K.5
Zhao, Y.6
Zhao, J.7
-
179
-
-
80755189006
-
The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1
-
22036506
-
Torrino S, Visvikis O, Doye A, Boyer L, Stefani C, Munro P, Bertoglio J, Gacon G, Mettouchi A, Lemichez E (2011) The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1. Dev Cell 21:959-965
-
(2011)
Dev Cell
, vol.21
, pp. 959-965
-
-
Torrino, S.1
Visvikis, O.2
Doye, A.3
Boyer, L.4
Stefani, C.5
Munro, P.6
Bertoglio, J.7
Gacon, G.8
Mettouchi, A.9
Lemichez, E.10
-
180
-
-
78149280470
-
SUMOylation of the GTPase Rac1 is required for optimal cell migration
-
2992316 20935639
-
Castillo-Lluva S, Tatham MH, Jones RC, Jaffray EG, Edmondson RD, Hay RT, Malliri A (2010) SUMOylation of the GTPase Rac1 is required for optimal cell migration. Nat Cell Biol 12:1078-1085
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1078-1085
-
-
Castillo-Lluva, S.1
Tatham, M.H.2
Jones, R.C.3
Jaffray, E.G.4
Edmondson, R.D.5
Hay, R.T.6
Malliri, A.7
-
181
-
-
84859950102
-
RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility
-
3340185 22393046
-
Yu J, Zhang D, Liu J, Li J, Yu Y, Wu XR, Huang C (2012) RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility. J Biol Chem 287:13752-13760
-
(2012)
J Biol Chem
, vol.287
, pp. 13752-13760
-
-
Yu, J.1
Zhang, D.2
Liu, J.3
Li, J.4
Yu, Y.5
Wu, X.R.6
Huang, C.7
-
182
-
-
79955538129
-
X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton
-
3091172 21402697
-
Liu J, Zhang D, Luo W, Yu Y, Yu J, Li J, Zhang X, Zhang B, Chen J, Wu XR, Rosas-Acosta G, Huang C (2011) X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton. J Biol Chem 286:15630-15640
-
(2011)
J Biol Chem
, vol.286
, pp. 15630-15640
-
-
Liu, J.1
Zhang, D.2
Luo, W.3
Yu, Y.4
Yu, J.5
Li, J.6
Zhang, X.7
Zhang, B.8
Chen, J.9
Wu, X.R.10
Rosas-Acosta, G.11
Huang, C.12
-
183
-
-
21744432683
-
GDIs: Central regulatory molecules in Rho GTPase activation
-
DOI 10.1016/j.tcb.2005.05.001, PII S0962892405001273
-
DerMardirossian C, Bokoch GM (2005) GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol 15:356-363 (Pubitemid 40943524)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.7
, pp. 356-363
-
-
DerMardirossian, C.1
Bokoch, G.M.2
-
184
-
-
0025073547
-
Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins
-
2120668
-
Fukumoto Y, Kaibuchi K, Hori Y, Fujioka H, Araki S, Ueda T, Kikuchi A, Takai Y (1990) Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. Oncogene 5:1321-1328
-
(1990)
Oncogene
, vol.5
, pp. 1321-1328
-
-
Fukumoto, Y.1
Kaibuchi, K.2
Hori, Y.3
Fujioka, H.4
Araki, S.5
Ueda, T.6
Kikuchi, A.7
Takai, Y.8
-
185
-
-
0026475383
-
The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein
-
1429634
-
Leonard D, Hart MJ, Platko JV, Eva A, Henzel W, Evans T, Cerione RA (1992) The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein. J Biol Chem 267:22860-22868
-
(1992)
J Biol Chem
, vol.267
, pp. 22860-22868
-
-
Leonard, D.1
Hart, M.J.2
Platko, J.V.3
Eva, A.4
Henzel, W.5
Evans, T.6
Cerione, R.A.7
-
186
-
-
77951974893
-
Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1
-
2866742 20400958
-
Boulter E, Garcia-Mata R, Guilluy C, Dubash A, Rossi G, Brennwald PJ, Burridge K (2010) Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1. Nat Cell Biol 12:477-483
-
(2010)
Nat Cell Biol
, vol.12
, pp. 477-483
-
-
Boulter, E.1
Garcia-Mata, R.2
Guilluy, C.3
Dubash, A.4
Rossi, G.5
Brennwald, P.J.6
Burridge, K.7
-
187
-
-
70349782157
-
Morphological and proliferative abnormalities in renal mesangial cells lacking RhoGDI
-
2903048 19765647
-
Bielek H, Anselmo A, Dermardirossian C (2009) Morphological and proliferative abnormalities in renal mesangial cells lacking RhoGDI. Cell Signal 21:1974-1983
-
(2009)
Cell Signal
, vol.21
, pp. 1974-1983
-
-
Bielek, H.1
Anselmo, A.2
Dermardirossian, C.3
-
188
-
-
84862773457
-
Rho GTPase regulation by miRNAs and covalent modifications
-
3383930 22572609
-
Liu M, Bi F, Zhou X, Zheng Y (2012) Rho GTPase regulation by miRNAs and covalent modifications. Trends Cell Biol 22:365-373
-
(2012)
Trends Cell Biol
, vol.22
, pp. 365-373
-
-
Liu, M.1
Bi, F.2
Zhou, X.3
Zheng, Y.4
-
189
-
-
53449092587
-
Cdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activation
-
18562481
-
Ispanovic E, Serio D, Haas TL (2008) Cdc42 and RhoA have opposing roles in regulating membrane type 1-matrix metalloproteinase localization and matrix metalloproteinase-2 activation. Am J Physiol Cell Physiol 295:C600-C610
-
(2008)
Am J Physiol Cell Physiol
, vol.295
-
-
Ispanovic, E.1
Serio, D.2
Haas, T.L.3
-
190
-
-
84871220416
-
FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration
-
Saito K, Ozawa Y, Hibino K, Ohta Y (2012) FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration. Mol Biol Cell 23:4739-4750
-
(2012)
Mol Biol Cell
, vol.23
, pp. 4739-4750
-
-
Saito, K.1
Ozawa, Y.2
Hibino, K.3
Ohta, Y.4
-
191
-
-
84867917134
-
Hic-5 affects proliferation, migration and invasion of B16 murine melanoma cells
-
22883018
-
Noguchi F, Inui S, Nakajima T, Itami S (2012) Hic-5 affects proliferation, migration and invasion of B16 murine melanoma cells. Pigment Cell Melanoma Res 25:773-782
-
(2012)
Pigment Cell Melanoma Res
, vol.25
, pp. 773-782
-
-
Noguchi, F.1
Inui, S.2
Nakajima, T.3
Itami, S.4
-
192
-
-
79951863284
-
EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells
-
21205836
-
Taddei ML, Parri M, Angelucci A, Bianchini F, Marconi C, Giannoni E, Raugei G, Bologna M, Calorini L, Chiarugi P (2011) EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells. Mol Cancer Res 9:149-160
-
(2011)
Mol Cancer Res
, vol.9
, pp. 149-160
-
-
Taddei, M.L.1
Parri, M.2
Angelucci, A.3
Bianchini, F.4
Marconi, C.5
Giannoni, E.6
Raugei, G.7
Bologna, M.8
Calorini, L.9
Chiarugi, P.10
-
193
-
-
77951587879
-
Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC
-
20101212
-
Kitzing TM, Wang Y, Pertz O, Copeland JW, Grosse R (2010) Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC. Oncogene 29:2441-2448
-
(2010)
Oncogene
, vol.29
, pp. 2441-2448
-
-
Kitzing, T.M.1
Wang, Y.2
Pertz, O.3
Copeland, J.W.4
Grosse, R.5
-
194
-
-
84857345144
-
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions
-
3288737 22305756
-
Omelchenko T, Hall A (2012) Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions. Curr Biol 22:278-288
-
(2012)
Curr Biol
, vol.22
, pp. 278-288
-
-
Omelchenko, T.1
Hall, A.2
-
195
-
-
33845873289
-
Interactive Tree Of Life (iTOL): An online tool for phylogenetic tree display and annotation
-
DOI 10.1093/bioinformatics/btl529
-
Letunic I, Bork P (2007) Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation. Bioinformatics 23:127-128 (Pubitemid 46017867)
-
(2007)
Bioinformatics
, vol.23
, Issue.1
, pp. 127-128
-
-
Letunic, I.1
Bork, P.2
|