Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 31, 2011, Pages 12851-12856

  Li, Nan ^a   Jiang, Peng ^b   Du, Wenjing ^b   Wu, Zhengsheng ^c   Li, Cong ^a   Qiao, Mengran ^a   Yang, Xiaolu ^b   Wu, Mian ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

CaMKII; Cell motility; Tumor metastasis

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; PEPTIDES AND PROTEINS; PROTEIN SIVA1; STATHMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST METASTASIS; BREAST TUMOR; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; FOCAL ADHESION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MEMBRANE STABILIZATION; METASTASIS; METASTASIS INHIBITION; MICROTUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TUMOR CELL; TUMOR CELL LINE;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; BREAST NEOPLASMS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULES; NEOPLASM METASTASIS; NEOPLASMS; NEOPLASMS, EXPERIMENTAL; PHOSPHORYLATION; PROTEIN BINDING; RNA INTERFERENCE; SERINE; STATHMIN;

EID: 79961234301     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1017372108     Document Type: Article

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