Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process

FEBS Journal

Volumn 275, Issue 2, 2008, Pages 386-396

  Visvikis, Orane ^a,b   Lorès, Patrick ^a,b   Boyer, Laurent ^b   Chardin, Pierre ^c   Lemichez, Emmanuel ^b   Gacon, Gérard ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

JNK; Rac1b; Rho GTPases; Ubiquitination

Indexed keywords

COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; POLYLYSINE; PROTEASOME; RAC1 PROTEIN; RAC1B PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL STRAIN HEK293; ENZYME ACTIVATION; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; UBIQUITINATION;

BLOTTING, WESTERN; CELL LINE; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LYSINE; MAP KINASE KINASE 4; PROTEIN ISOFORMS; RAC1 GTP-BINDING PROTEIN; UBIQUITIN;

EID: 37849050182     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06209.x     Document Type: Article

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