-
1
-
-
63049136592
-
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
-
Adorno M., Cordenonsi M., Montagner M., Dupont S., Wong C., Hann B., Solari A., Bobisse S., Rondina M.B., Guzzardo V., et al. A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 137 (2009) 87-98
-
(2009)
Cell
, vol.137
, pp. 87-98
-
-
Adorno, M.1
Cordenonsi, M.2
Montagner, M.3
Dupont, S.4
Wong, C.5
Hann, B.6
Solari, A.7
Bobisse, S.8
Rondina, M.B.9
Guzzardo, V.10
-
2
-
-
0033028043
-
The role of p53 in tumour suppression: lessons from mouse models
-
Attardi L.D., and Jacks T. The role of p53 in tumour suppression: lessons from mouse models. Cell. Mol. Life Sci. 55 (1999) 48-63
-
(1999)
Cell. Mol. Life Sci.
, vol.55
, pp. 48-63
-
-
Attardi, L.D.1
Jacks, T.2
-
3
-
-
0033809941
-
p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect
-
Blagosklonny M.V. p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect. FASEB J. 14 (2000) 1901-1907
-
(2000)
FASEB J.
, vol.14
, pp. 1901-1907
-
-
Blagosklonny, M.V.1
-
4
-
-
34547577319
-
p53 and its isoforms in cancer
-
Bourdon J.C. p53 and its isoforms in cancer. Br. J. Cancer 97 (2007) 277-282
-
(2007)
Br. J. Cancer
, vol.97
, pp. 277-282
-
-
Bourdon, J.C.1
-
5
-
-
13244275005
-
Integrin beta1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo
-
Brockbank E.C., Bridges J., Marshall C.J., and Sahai E. Integrin beta1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo. Br. J. Cancer 92 (2005) 102-112
-
(2005)
Br. J. Cancer
, vol.92
, pp. 102-112
-
-
Brockbank, E.C.1
Bridges, J.2
Marshall, C.J.3
Sahai, E.4
-
6
-
-
70349443284
-
When mutants gain new powers: news from the mutant p53 field
-
Brosh R., and Rotter V. When mutants gain new powers: news from the mutant p53 field. Nat. Rev. Cancer 9 (2009) 701-713
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 701-713
-
-
Brosh, R.1
Rotter, V.2
-
7
-
-
33845391172
-
Epigenetic modulation of endogenous suppressor expression in lung cancer xenografts suppresses igenicity
-
Cantor J.P., Iliopoulos D., Rao A.S., Druck T., Semba S., Han S.Y., McCorkell K.A., Lakshman T.V., Collins J.E., Wachsberger P., et al. Epigenetic modulation of endogenous suppressor expression in lung cancer xenografts suppresses igenicity. Int. J. Cancer 120 (2007) 24-31
-
(2007)
Int. J. Cancer
, vol.120
, pp. 24-31
-
-
Cantor, J.P.1
Iliopoulos, D.2
Rao, A.S.3
Druck, T.4
Semba, S.5
Han, S.Y.6
McCorkell, K.A.7
Lakshman, T.V.8
Collins, J.E.9
Wachsberger, P.10
-
8
-
-
33744796255
-
p63 regulates an adhesion programme and cell survival in epithelial cells
-
Carroll D.K., Carroll J.S., Leong C.O., Cheng F., Brown M., Mills A.A., Brugge J.S., and Ellisen L.W. p63 regulates an adhesion programme and cell survival in epithelial cells. Nat. Cell Biol. 8 (2006) 551-561
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 551-561
-
-
Carroll, D.K.1
Carroll, J.S.2
Leong, C.O.3
Cheng, F.4
Brown, M.5
Mills, A.A.6
Brugge, J.S.7
Ellisen, L.W.8
-
9
-
-
44649198353
-
Endocytic transport of integrins during cell migration and invasion
-
Caswell P., and Norman J. Endocytic transport of integrins during cell migration and invasion. Trends Cell Biol. 18 (2008) 257-263
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 257-263
-
-
Caswell, P.1
Norman, J.2
-
10
-
-
34848816931
-
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments
-
Caswell P.T., Spence H.J., Parsons M., White D.P., Clark K., Cheng K.W., Mills G.B., Humphries M.J., Messent A.J., Anderson K.I., et al. Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev. Cell 13 (2007) 496-510
-
(2007)
Dev. Cell
, vol.13
, pp. 496-510
-
-
Caswell, P.T.1
Spence, H.J.2
Parsons, M.3
White, D.P.4
Clark, K.5
Cheng, K.W.6
Mills, G.B.7
Humphries, M.J.8
Messent, A.J.9
Anderson, K.I.10
-
11
-
-
53749092962
-
Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments
-
Caswell P.T., Chan M., Lindsay A.J., McCaffrey M.W., Boettiger D., and Norman J.C. Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments. J. Cell Biol. 183 (2008) 143-155
-
(2008)
J. Cell Biol.
, vol.183
, pp. 143-155
-
-
Caswell, P.T.1
Chan, M.2
Lindsay, A.J.3
McCaffrey, M.W.4
Boettiger, D.5
Norman, J.C.6
-
12
-
-
0027983669
-
Crystal structure of a p53 suppressor-DNA complex: understanding igenic mutations
-
Cho Y., Gorina S., Jeffery P.D., and Pavletich N.P. Crystal structure of a p53 suppressor-DNA complex: understanding igenic mutations. Science 265 (1994) 346-355
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffery, P.D.3
Pavletich, N.P.4
-
13
-
-
0032560027
-
p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in humans
-
Epstein C.B., Attiyeh E.F., Hobson D.A., Silver A.L., Broach J.R., and Levine A.J. p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in humans. Oncogene 16 (1998) 2115-2122
-
(1998)
Oncogene
, vol.16
, pp. 2115-2122
-
-
Epstein, C.B.1
Attiyeh, E.F.2
Hobson, D.A.3
Silver, A.L.4
Broach, J.R.5
Levine, A.J.6
-
14
-
-
17444390129
-
Predisposition in mice mutant for p63 and p73: evidence for broader suppressor functions for the p53 family
-
Flores E.R., Sengupta S., Miller J.B., Newman J.J., Bronson R., Crowley D., Yang A., McKeon F., and Jacks T. Predisposition in mice mutant for p63 and p73: evidence for broader suppressor functions for the p53 family. Cancer Cell 7 (2005) 363-373
-
(2005)
Cancer Cell
, vol.7
, pp. 363-373
-
-
Flores, E.R.1
Sengupta, S.2
Miller, J.B.3
Newman, J.J.4
Bronson, R.5
Crowley, D.6
Yang, A.7
McKeon, F.8
Jacks, T.9
-
15
-
-
0035131701
-
A subset of tumor-derived mutant forms of p53 down-reulate p63 and p73 through a direct interaction with the p53 core domain
-
Gaiddon C., Lokshn M., Ahn J., Zhang T., and Prives C. A subset of tumor-derived mutant forms of p53 down-reulate p63 and p73 through a direct interaction with the p53 core domain. Mol. Cell. Biol. 21 (2001) 1874-1887
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1874-1887
-
-
Gaiddon, C.1
Lokshn, M.2
Ahn, J.3
Zhang, T.4
Prives, C.5
-
16
-
-
0035734285
-
Synergistic suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers J., Meuwissen R., van der Gulden H., Peterse H., van der Valk M., and Berns A. Synergistic suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat. Genet. 29 (2001) 418-425
-
(2001)
Nat. Genet.
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
van der Gulden, H.3
Peterse, H.4
van der Valk, M.5
Berns, A.6
-
17
-
-
0020316410
-
Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound
-
Kupfer A., Louvard D., and Singer S.J. Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. Proc. Natl. Acad. Sci. USA 79 (1982) 2603-2607
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, pp. 2603-2607
-
-
Kupfer, A.1
Louvard, D.2
Singer, S.J.3
-
18
-
-
0028124528
-
p53 and human cancers
-
Lane D.P. p53 and human cancers. Br. Med. Bull. 50 (1994) 582-599
-
(1994)
Br. Med. Bull.
, vol.50
, pp. 582-599
-
-
Lane, D.P.1
-
19
-
-
13644260907
-
Gain-of-function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
-
Lang G.A., Iwakuma T., Suh Y.-A., Liu G., Rao A., Parant J.M., Valentin-Vega Y.A., Terzian T., Caldwell L.C., Strong L.C., et al. Gain-of-function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell 119 (2004) 861-872
-
(2004)
Cell
, vol.119
, pp. 861-872
-
-
Lang, G.A.1
Iwakuma, T.2
Suh, Y.-A.3
Liu, G.4
Rao, A.5
Parant, J.M.6
Valentin-Vega, Y.A.7
Terzian, T.8
Caldwell, L.C.9
Strong, L.C.10
-
20
-
-
34047223196
-
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
-
Li Y., and Prives C. Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?. Oncogene 26 (2007) 2220-2225
-
(2007)
Oncogene
, vol.26
, pp. 2220-2225
-
-
Li, Y.1
Prives, C.2
-
21
-
-
0029062595
-
Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants
-
Lin J., Teresky A.K., and Levine A.J. Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants. Oncogene 10 (1995) 2387-2390
-
(1995)
Oncogene
, vol.10
, pp. 2387-2390
-
-
Lin, J.1
Teresky, A.K.2
Levine, A.J.3
-
22
-
-
56749183466
-
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation
-
Marsh V., Winton D.J., Williams G.T., Dubois N., Trumpp A., Sansom O.J., and Clarke A.R. Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation. Nat. Genet. 40 (2008) 1436-1444
-
(2008)
Nat. Genet.
, vol.40
, pp. 1436-1444
-
-
Marsh, V.1
Winton, D.J.2
Williams, G.T.3
Dubois, N.4
Trumpp, A.5
Sansom, O.J.6
Clarke, A.R.7
-
23
-
-
0035421961
-
Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis
-
Matas D., Sigal A., Stambolsky P., Milyavsky M., Weisz L., Schwartz D., Goldfinger N., and Rotter V. Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis. EMBO J. 20 (2001) 4163-4172
-
(2001)
EMBO J.
, vol.20
, pp. 4163-4172
-
-
Matas, D.1
Sigal, A.2
Stambolsky, P.3
Milyavsky, M.4
Weisz, L.5
Schwartz, D.6
Goldfinger, N.7
Rotter, V.8
-
24
-
-
0034854417
-
ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
-
Muthuswamy S.K., Li D., Lelievre S., Bissell M.J., and Brugge J.S. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nat. Cell Biol. 3 (2001) 785-792
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 785-792
-
-
Muthuswamy, S.K.1
Li, D.2
Lelievre, S.3
Bissell, M.J.4
Brugge, J.S.5
-
25
-
-
10944236962
-
Mutant p53 gain-of-function in two mouse models of Li-Fraumeni syndrome
-
Olive K.P., Tuveson D.A., Ruhe Z.C., Yin B., Willis N.A., Bronson R.T., Crowley D., and Jacks T. Mutant p53 gain-of-function in two mouse models of Li-Fraumeni syndrome. Cell 119 (2004) 847-860
-
(2004)
Cell
, vol.119
, pp. 847-860
-
-
Olive, K.P.1
Tuveson, D.A.2
Ruhe, Z.C.3
Yin, B.4
Willis, N.A.5
Bronson, R.T.6
Crowley, D.7
Jacks, T.8
-
26
-
-
34047207337
-
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
-
Petitjean A., Achatz M.I., Borresen-Dale A.L., Hainaut P., and Olivier M. TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 26 (2007) 2157-2165
-
(2007)
Oncogene
, vol.26
, pp. 2157-2165
-
-
Petitjean, A.1
Achatz, M.I.2
Borresen-Dale, A.L.3
Hainaut, P.4
Olivier, M.5
-
27
-
-
0035908956
-
PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading
-
Roberts M., Barry S., Woods A., van der Sluijs P., and Norman J. PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading. Curr. Biol. 11 (2001) 1392-1402
-
(2001)
Curr. Biol.
, vol.11
, pp. 1392-1402
-
-
Roberts, M.1
Barry, S.2
Woods, A.3
van der Sluijs, P.4
Norman, J.5
-
28
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
Sansom O.J., Reed K.R., Hayes A.J., Ireland H., Brinkmann H., Newton I.P., Batlle E., Simon-Assmann P., Clevers H., Nathke I.S., et al. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev. 18 (2004) 1385-1390
-
(2004)
Genes Dev.
, vol.18
, pp. 1385-1390
-
-
Sansom, O.J.1
Reed, K.R.2
Hayes, A.J.3
Ireland, H.4
Brinkmann, H.5
Newton, I.P.6
Batlle, E.7
Simon-Assmann, P.8
Clevers, H.9
Nathke, I.S.10
-
29
-
-
33748988989
-
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo
-
Sansom O.J., Meniel V., Wilkins J.A., Cole A.M., Oien K.A., Marsh V., Jamieson T.J., Guerra C., Ashton G.H., Barbacid M., et al. Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo. Proc. Natl. Acad. Sci. USA 103 (2006) 14122-14127
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14122-14127
-
-
Sansom, O.J.1
Meniel, V.2
Wilkins, J.A.3
Cole, A.M.4
Oien, K.A.5
Marsh, V.6
Jamieson, T.J.7
Guerra, C.8
Ashton, G.H.9
Barbacid, M.10
-
30
-
-
0036229694
-
Networks and crosstalk: integrin signalling spreads
-
Schwartz M.A., and Ginsberg M.H. Networks and crosstalk: integrin signalling spreads. Nat. Cell Biol. 4 (2002) E65-E68
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
Schwartz, M.A.1
Ginsberg, M.H.2
-
31
-
-
0842320996
-
Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells
-
Seton-Rogers S.E., Lu Y., Hines L.M., Koundinya M., LaBaer J., Muthuswamy S.K., and Brugge J.S. Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells. Proc. Natl. Acad. Sci. USA 101 (2004) 1257-1262
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1257-1262
-
-
Seton-Rogers, S.E.1
Lu, Y.2
Hines, L.M.3
Koundinya, M.4
LaBaer, J.5
Muthuswamy, S.K.6
Brugge, J.S.7
-
32
-
-
0034671945
-
Oncogenic mutations of the p53 suppressor: the demons of the guardian of the genome
-
Sigal A., and Rotter V. Oncogenic mutations of the p53 suppressor: the demons of the guardian of the genome. Cancer Res. 60 (2000) 6788-6793
-
(2000)
Cancer Res.
, vol.60
, pp. 6788-6793
-
-
Sigal, A.1
Rotter, V.2
-
33
-
-
0033931447
-
The p53 suppressor gene: from molecular biology to clinical investigation
-
Soussi T. The p53 suppressor gene: from molecular biology to clinical investigation. Ann. N Y Acad. Sci. 910 (2000) 121-137
-
(2000)
Ann. N Y Acad. Sci.
, vol.910
, pp. 121-137
-
-
Soussi, T.1
-
34
-
-
18544364361
-
Physical interaction with human derived p53 mutants inhibits p63 activities
-
Strano S., Fontemaggi G., Costanzo A., Rizzo M.G., Monti O., Baccarini A., Del Sal G., Levrero M., Sacchi A., Oren M., et al. Physical interaction with human derived p53 mutants inhibits p63 activities. J. Biol. Chem. 277 (2002) 18817-18826
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18817-18826
-
-
Strano, S.1
Fontemaggi, G.2
Costanzo, A.3
Rizzo, M.G.4
Monti, O.5
Baccarini, A.6
Del Sal, G.7
Levrero, M.8
Sacchi, A.9
Oren, M.10
-
36
-
-
65349103899
-
Blinded by the light: the growing complexity of p53
-
Vousden K.H., and Prives C. Blinded by the light: the growing complexity of p53. Cell 137 (2009) 413-431
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
37
-
-
34248226275
-
alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration
-
White D.P., Caswell P.T., and Norman J.C. alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration. J. Cell Biol. 177 (2007) 515-525
-
(2007)
J. Cell Biol.
, vol.177
, pp. 515-525
-
-
White, D.P.1
Caswell, P.T.2
Norman, J.C.3
-
38
-
-
68849084073
-
RCP is a human breast cancer-promoting gene with Ras-activating function
-
Zhang J., Liu X., Datta A., Govindarajan K., Tam W.L., Han J., George J., Wong C., Ramnarayanan K., Phua T.Y., et al. RCP is a human breast cancer-promoting gene with Ras-activating function. J. Clin. Invest. 119 (2009) 2171-2183
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2171-2183
-
-
Zhang, J.1
Liu, X.2
Datta, A.3
Govindarajan, K.4
Tam, W.L.5
Han, J.6
George, J.7
Wong, C.8
Ramnarayanan, K.9
Phua, T.Y.10
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