메뉴 건너뛰기




Volumn 2, Issue 6, 2011, Pages 491-496

P21-activated kinase 1: PAK'ed with potential

Author keywords

Apoptosis; Breast cancer; Lung cancer; PAK1; Squamous

Indexed keywords

ANTINEOPLASTIC AGENT; BEVACIZUMAB; ERLOTINIB; GEFITINIB; P21 ACTIVATED KINASE 1; TAMOXIFEN; P21 ACTIVATED KINASE; PROTEIN KINASE INHIBITOR;

EID: 80555126205     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.271     Document Type: Article
Times cited : (46)

References (44)
  • 3
    • 0032561206 scopus 로고    scopus 로고
    • Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
    • Adam L, Vadlamudi R, Kondapaka SB, Chernoff J, Mendelsohn J, Kumar R. Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase. J Biol Chem. 1998; 273: 28238-46.
    • (1998) J Biol Chem , vol.273 , pp. 28238-28246
    • Adam, L.1    Vadlamudi, R.2    Kondapaka, S.B.3    Chernoff, J.4    Mendelsohn, J.5    Kumar, R.6
  • 7
    • 34547753507 scopus 로고    scopus 로고
    • P21-activated kinase 1 a new molecular marker for intravesical recurrence after transurethral resection of bladder cancer
    • Ito M, Nishiyama H, Kawanishi H, Matsui S, Guilford P, Reeve A, Ogawa O. P21-activated kinase 1: a new molecular marker for intravesical recurrence after transurethral resection of bladder cancer. J Urol. 2007; 178: 1073-9.
    • (2007) J Urol , vol.178 , pp. 1073-1079
    • Ito, M.1    Nishiyama, H.2    Kawanishi, H.3    Matsui, S.4    Guilford, P.5    Reeve, A.6    Ogawa, O.7
  • 8
    • 0041423391 scopus 로고    scopus 로고
    • Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13 5-q14 as a critical oncogene target in ovarian carcinoma
    • Schraml P, Schwerdtfeger G, Burkhalter F, Raggi A, Schmidt D, Ruffalo T, King W, Wilber K, Mihatsch MJ, Moch H. Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma. Am J Pathol. 2003; 163: 985-92.
    • (2003) Am J Pathol , vol.163 , pp. 985-992
    • Schraml, P.1    Schwerdtfeger, G.2    Burkhalter, F.3    Raggi, A.4    Schmidt, D.5    Ruffalo, T.6    King, W.7    Wilber, K.8    Mihatsch, M.J.9    Moch, H.10
  • 9
    • 33646940460 scopus 로고    scopus 로고
    • Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients
    • Holm C, Rayala S, Jirstrom K, Stal O, Kumar R, Landberg G. Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. J Natl Cancer Inst. 2006; 98: 671-80.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 671-680
    • Holm, C.1    Rayala, S.2    Jirstrom, K.3    Stal, O.4    Kumar, R.5    Landberg, G.6
  • 10
    • 32944473985 scopus 로고    scopus 로고
    • P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation
    • Rayala SK, Talukder AH, Balasenthil S, Tharakan R, Barnes CJ, Wang RA, Aldaz M, Khan S, Kumar R. P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation. Cancer Res. 2006; 66: 1694-701.
    • (2006) Cancer Res , vol.66 , pp. 1694-1701
    • Rayala, S.K.1    Talukder, A.H.2    Balasenthil, S.3    Tharakan, R.4    Barnes, C.J.5    Wang, R.A.6    Aldaz, M.7    Khan, S.8    Kumar, R.9
  • 11
    • 0034680834 scopus 로고    scopus 로고
    • Regulatable expression of p21-activated kinase-1 promotes anchorageindependent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells
    • Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R. Regulatable expression of p21-activated kinase-1 promotes anchorageindependent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J Biol Chem. 2000; 275: 36238-44.
    • (2000) J Biol Chem , vol.275 , pp. 36238-36244
    • Vadlamudi, R.K.1    Adam, L.2    Wang, R.A.3    Mandal, M.4    Nguyen, D.5    Sahin, A.6    Chernoff, J.7    Hung, M.C.8    Kumar, R.9
  • 12
    • 33646682385 scopus 로고    scopus 로고
    • PAK1 hyperactivation is sufficient for mammary gland tumor formation
    • Wang RA, Zhang H, Balasenthil S, Medina D, Kumar R. PAK1 hyperactivation is sufficient for mammary gland tumor formation. Oncogene. 2006; 25: 2931-6.
    • (2006) Oncogene , vol.25 , pp. 2931-2936
    • Wang, R.A.1    Zhang, H.2    Balasenthil, S.3    Medina, D.4    Kumar, R.5
  • 14
    • 80052043279 scopus 로고    scopus 로고
    • miRNA signature of schwannomas: possible role(s) of "tumor suppressor" miRNAs in benign tumors
    • Erkan EP, Breakefield XO, Saydam O. miRNA signature of schwannomas: possible role(s) of "tumor suppressor" miRNAs in benign tumors. Oncotarget. 2011; 2: 265-70.
    • (2011) Oncotarget , vol.2 , pp. 265-270
    • Erkan, E.P.1    Breakefield, X.O.2    Saydam, O.3
  • 16
    • 67649464367 scopus 로고    scopus 로고
    • Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development
    • Lightcap CM, Kari G, Arias-Romero LE, Chernoff J, Rodeck U, Williams JC. Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development. PLoS One. 2009; 4: e6025.
    • (2009) PLoS One , vol.4
    • Lightcap, C.M.1    Kari, G.2    Arias-Romero, L.E.3    Chernoff, J.4    Rodeck, U.5    Williams, J.C.6
  • 19
    • 61449249141 scopus 로고    scopus 로고
    • Balancing the decision of cell proliferation and cell fate
    • Hallstrom TC, Nevins JR. Balancing the decision of cell proliferation and cell fate. Cell Cycle. 2009; 8: 532-5.
    • (2009) Cell Cycle , vol.8 , pp. 532-535
    • Hallstrom, T.C.1    Nevins, J.R.2
  • 20
    • 78751505998 scopus 로고    scopus 로고
    • p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies
    • Wander SA, Zhao D, Slingerland JM. p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies. Clin Cancer Res. 2010; 17: 12-8.
    • (2010) Clin Cancer Res , vol.17 , pp. 12-18
    • Wander, S.A.1    Zhao, D.2    Slingerland, J.M.3
  • 23
    • 34447549285 scopus 로고    scopus 로고
    • Differences in epidemiology, histology, and survival between cigarette smokers and never-smokers who develop non-small cell lung cancer
    • Bryant A, Cerfolio RJ. Differences in epidemiology, histology, and survival between cigarette smokers and never-smokers who develop non-small cell lung cancer. Chest. 2007; 132: 185-92.
    • (2007) Chest , vol.132 , pp. 185-192
    • Bryant, A.1    Cerfolio, R.J.2
  • 28
    • 85039684983 scopus 로고    scopus 로고
    • Avastin Prescribing Information
    • Avastin Prescribing Information. [http://wwwgenecom/gene/products/information/pdf/avastin-prescribingpdf].
  • 29
    • 85039682305 scopus 로고    scopus 로고
    • Tarceva Prescribing Information
    • Tarceva Prescribing Information. [http://wwwgenecom/gene/products/information/pdf/tarceva-prescribingpdf].
  • 30
    • 85039686429 scopus 로고    scopus 로고
    • NCCN Guidelines for Treatment of Cancer by Site
    • NCCN Guidelines for Treatment of Cancer by Site. [http://www.nccn.org/professionals/physician_gls/f_ guidelines.asp].
  • 33
    • 54249093368 scopus 로고    scopus 로고
    • MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions
    • Reddy SD, Ohshiro K, Rayala SK, Kumar R. MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions. Cancer Res. 2008; 68: 8195-200.
    • (2008) Cancer Res , vol.68 , pp. 8195-8200
    • Reddy, S.D.1    Ohshiro, K.2    Rayala, S.K.3    Kumar, R.4
  • 34
    • 44849093562 scopus 로고    scopus 로고
    • Oncogene addiction
    • Weinstein IB, Joe A. Oncogene addiction. Cancer Res. 2008; 68: 3077-80.
    • (2008) Cancer Res , vol.68 , pp. 3077-3080
    • Weinstein, I.B.1    Joe, A.2
  • 37
  • 38
    • 78249255518 scopus 로고    scopus 로고
    • Chernoff J. p21-Activated kinases are required for transformation in a cell-based model of neurofibromatosis type 2
    • Chow HY, Stepanova D, Koch J, Chernoff J. p21-Activated kinases are required for transformation in a cell-based model of neurofibromatosis type 2. PLoS One. 2010; 5: e13791.
    • (2010) PLoS One , vol.5
    • Chow, H.Y.1    Stepanova, D.2    Koch, J.3
  • 39
    • 78149466325 scopus 로고    scopus 로고
    • The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis
    • Liu Y, Chen N, Cui X, Zheng X, Deng L, Price S, Karantza V, Minden A. The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis. Oncogene. 2010; 29: 5883-94.
    • (2010) Oncogene , vol.29 , pp. 5883-5894
    • Liu, Y.1    Chen, N.2    Cui, X.3    Zheng, X.4    Deng, L.5    Price, S.6    Karantza, V.7    Minden, A.8
  • 41
    • 33749334697 scopus 로고    scopus 로고
    • Using genetically engineered mouse models of cancer to aid drug development: an industry perspective
    • Singh M, Johnson L. Using genetically engineered mouse models of cancer to aid drug development: an industry perspective. Clin Cancer Res. 2006; 12: 5312-28.
    • (2006) Clin Cancer Res , vol.12 , pp. 5312-5328
    • Singh, M.1    Johnson, L.2
  • 44
    • 0034733041 scopus 로고    scopus 로고
    • Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1
    • Frost JA, Swantek JL, Stippec S, Yin MJ, Gaynor R, Cobb MH. Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1. J Biol Chem. 2000; 275: 19693-9.
    • (2000) J Biol Chem , vol.275 , pp. 19693-19699
    • Frost, J.A.1    Swantek, J.L.2    Stippec, S.3    Yin, M.J.4    Gaynor, R.5    Cobb, M.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.