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Volumn 1, Issue 2, 2010, Pages 113-117

Integrating chemotaxis and contact-inhibition during collective cell migration: Small GTPases at work

Author keywords

Cadherins; Chemotaxis; Collective cell migration; Contact inhibition of locomotion; Neural crest cells; Rac1; RhoA; Stromal cell derived factor 1

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GUANOSINE TRIPHOSPHATASE; NERVE CELL ADHESION MOLECULE; PHOSPHATIDYLINOSITOL 3 KINASE; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; SYNDECAN 4;

EID: 79952046499     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.1.2.13673     Document Type: Article
Times cited : (50)

References (38)
  • 1
    • 33947206045 scopus 로고    scopus 로고
    • Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions
    • Andrew N, Insall RH. Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions. Nat Cell Biol 2007; 9:193-200.
    • (2007) Nat Cell Biol , vol.9 , pp. 193-200
    • Andrew, N.1    Insall, R.H.2
  • 2
    • 33745607882 scopus 로고    scopus 로고
    • Feedback signaling controls leading-edge formation during chemotaxis
    • Charest PG, Firtel RA. Feedback signaling controls leading-edge formation during chemotaxis. Curr Opin Genet Dev 2006; 16:339-47.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 339-347
    • Charest, P.G.1    Firtel, R.A.2
  • 3
    • 67649528138 scopus 로고    scopus 로고
    • Collective cell migration in morphogenesis, regeneration and cancer
    • Friedl P, Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 2009; 10:445-57.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 445-457
    • Friedl, P.1    Gilmour, D.2
  • 4
    • 77952955309 scopus 로고    scopus 로고
    • Understanding eukaryotic chemotaxis: A pseudopod-centred view
    • Insall RH. Understanding eukaryotic chemotaxis: a pseudopod-centred view. Nat Rev Mol Cell Biol 2010; 11:453-8.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 453-458
    • Insall, R.H.1
  • 5
    • 70350228491 scopus 로고    scopus 로고
    • Collective cell migration
    • Rorth P. Collective cell migration. Annu Rev Cell Dev Biol 2009; 25:407-29.
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 407-429
    • Rorth, P.1
  • 7
    • 67650730269 scopus 로고    scopus 로고
    • Chemokine signaling in embryonic cell migration: A fisheye view
    • Raz E, Mahabaleshwar H. Chemokine signaling in embryonic cell migration: a fisheye view. Development 2009; 136:1223-9.
    • (2009) Development , vol.136 , pp. 1223-1229
    • Raz, E.1    Mahabaleshwar, H.2
  • 9
    • 0001724467 scopus 로고
    • Social behaviour of cells in tissue culture. III. Mutual influence of sarcoma cells and fibroblasts
    • Abercrombie M, Heaysman JE, Karthauser HM. Social behaviour of cells in tissue culture. III. Mutual influence of sarcoma cells and fibroblasts. Exp Cell Res 1957; 13:276-91.
    • (1957) Exp Cell Res , vol.13 , pp. 276-291
    • Abercrombie, M.1    Heaysman, J.E.2    Karthauser, H.M.3
  • 10
    • 77953539835 scopus 로고    scopus 로고
    • Keeping in touch with contact inhibition of locomotion
    • Mayor R, Carmona-Fontaine C. Keeping in touch with contact inhibition of locomotion. Trends Cell Biol 2010; 20:319-28.
    • (2010) Trends Cell Biol , vol.20 , pp. 319-328
    • Mayor, R.1    Carmona-Fontaine, C.2
  • 11
    • 49949088657 scopus 로고    scopus 로고
    • Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/ RhoA
    • Matthews HK, Marchant L, Carmona-Fontaine C, Kuriyama S, Larrain J, Holt MR, et al. Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/ RhoA. Development 2008; 135:1771-80.
    • (2008) Development , vol.135 , pp. 1771-1780
    • Matthews, H.K.1    Marchant, L.2    Carmona-Fontaine, C.3    Kuriyama, S.4    Larrain, J.5    Holt, M.R.6
  • 12
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 1999; 147:1009-22.
    • (1999) J Cell Biol , vol.147 , pp. 1009-1022
    • Sander, E.E.1    ten Klooster, J.P.2    van Delft, S.3    van der Kammen, R.A.4    Collard, J.G.5
  • 13
    • 0035374569 scopus 로고    scopus 로고
    • RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway
    • Yamaguchi Y, Katoh H, Yasui H, Mori K, Negishi M. RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway. J Biol Chem 2001; 276:18977-83.
    • (2001) J Biol Chem , vol.276 , pp. 18977-18983
    • Yamaguchi, Y.1    Katoh, H.2    Yasui, H.3    Mori, K.4    Negishi, M.5
  • 14
    • 0033174147 scopus 로고    scopus 로고
    • Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading
    • van Leeuwen FN, van Delft S, Kain HE, van der Kammen RA, Collard JG. Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. Nat Cell Biol 1999; 1:242-8.
    • (1999) Nat Cell Biol , vol.1 , pp. 242-248
    • van Leeuwen, F.N.1    van Delft, S.2    Kain, H.E.3    van der Kammen, R.A.4    Collard, J.G.5
  • 15
    • 0034618050 scopus 로고    scopus 로고
    • p120 catenin regulates the actin cytoskeleton via Rho family GTPases
    • Noren NK, Liu BP, Burridge K, Kreft B. p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol 2000; 150:567-80.
    • (2000) J Cell Biol , vol.150 , pp. 567-580
    • Noren, N.K.1    Liu, B.P.2    Burridge, K.3    Kreft, B.4
  • 16
    • 0037009074 scopus 로고    scopus 로고
    • N-cadherin-dependent cellcell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts
    • Charrasse S, Meriane M, Comunale F, Blangy A, Gauthier-Rouviere C. N-cadherin-dependent cellcell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts. J Cell Biol 2002; 158:953-65.
    • (2002) J Cell Biol , vol.158 , pp. 953-965
    • Charrasse, S.1    Meriane, M.2    Comunale, F.3    Blangy, A.4    Gauthier-Rouviere, C.5
  • 19
    • 0032483419 scopus 로고    scopus 로고
    • The alpha-chemokine, stromal cellderived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
    • Ganju RK, Brubaker SA, Meyer J, Dutt P, Yang Y, Qin S, et al. The alpha-chemokine, stromal cellderived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem 1998; 273:23169-75.
    • (1998) J Biol Chem , vol.273 , pp. 23169-23175
    • Ganju, R.K.1    Brubaker, S.A.2    Meyer, J.3    Dutt, P.4    Yang, Y.5    Qin, S.6
  • 20
    • 0033486065 scopus 로고    scopus 로고
    • The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes
    • Sotsios Y, Whittaker GC, Westwick J, Ward SG. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J Immunol 1999; 163:5954-63.
    • (1999) J Immunol , vol.163 , pp. 5954-5963
    • Sotsios, Y.1    Whittaker, G.C.2    Westwick, J.3    Ward, S.G.4
  • 22
    • 0037415640 scopus 로고    scopus 로고
    • Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis
    • Srinivasan S, Wang F, Glavas S, Ott A, Hofmann F, Aktories K, et al. Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. J Cell Biol 2003; 160:375-85.
    • (2003) J Cell Biol , vol.160 , pp. 375-385
    • Srinivasan, S.1    Wang, F.2    Glavas, S.3    Ott, A.4    Hofmann, F.5    Aktories, K.6
  • 26
    • 77149152165 scopus 로고    scopus 로고
    • Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration and in vitro angiogenesis
    • Carretero-Ortega J, Walsh CT, Hernandez-Garcia R, Reyes-Cruz G, Brown JH, Vazquez-Prado J. Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration and in vitro angiogenesis. Mol Pharmacol 2010; 77:435-42.
    • (2010) Mol Pharmacol , vol.77 , pp. 435-442
    • Carretero-Ortega, J.1    Walsh, C.T.2    Hernandez-Garcia, R.3    Reyes-Cruz, G.4    Brown, J.H.5    Vazquez-Prado, J.6
  • 27
    • 19944428599 scopus 로고    scopus 로고
    • Incorporation of CXCR4 into membrane lipid rafts primes homingrelated responses of hematopoietic stem/progenitor cells to an SDF-1 gradient
    • Wysoczynski M, Reca R, Ratajczak J, Kucia M, Shirvaikar N, Honczarenko M, et al. Incorporation of CXCR4 into membrane lipid rafts primes homingrelated responses of hematopoietic stem/progenitor cells to an SDF-1 gradient. Blood 2005; 105:40-8.
    • (2005) Blood , vol.105 , pp. 40-48
    • Wysoczynski, M.1    Reca, R.2    Ratajczak, J.3    Kucia, M.4    Shirvaikar, N.5    Honczarenko, M.6
  • 28
    • 17644367566 scopus 로고    scopus 로고
    • H-Rasspecific activation of Rac-MKK3/6-p38 pathway: Its critical role in invasion and migration of breast epithelial cells
    • Shin I, Kim S, Song H, Kim HR, Moon A. H-Rasspecific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells. J Biol Chem 2005; 280:14675-83.
    • (2005) J Biol Chem , vol.280 , pp. 14675-14683
    • Shin, I.1    Kim, S.2    Song, H.3    Kim, H.R.4    Moon, A.5
  • 29
    • 33947600329 scopus 로고    scopus 로고
    • Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma
    • Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, et al. Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood 2007; 109:2708-17.
    • (2007) Blood , vol.109 , pp. 2708-2717
    • Alsayed, Y.1    Ngo, H.2    Runnels, J.3    Leleu, X.4    Singha, U.K.5    Pitsillides, C.M.6
  • 30
    • 69249247048 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/ CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NFkappaBdependent pathways
    • Huang CY, Lee CY, Chen MY, Yang WH, Chen YH, Chang CH, et al. Stromal cell-derived factor-1/ CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NFkappaBdependent pathways. J Cell Physiol 2009; 221:204-12.
    • (2009) J Cell Physiol , vol.221 , pp. 204-212
    • Huang, C.Y.1    Lee, C.Y.2    Chen, M.Y.3    Yang, W.H.4    Chen, Y.H.5    Chang, C.H.6
  • 31
    • 0038281350 scopus 로고    scopus 로고
    • Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens
    • Zhong B, Jiang K, Gilvary DL, Epling-Burnette PK, Ritchey C, Liu J, et al. Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens. Blood 2003; 101:3240-8.
    • (2003) Blood , vol.101 , pp. 3240-3248
    • Zhong, B.1    Jiang, K.2    Gilvary, D.L.3    Epling-Burnette, P.K.4    Ritchey, C.5    Liu, J.6
  • 32
    • 50649083968 scopus 로고    scopus 로고
    • SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NFkappaB
    • Rehman AO, Wang CY. SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NFkappaB. J Biol Chem 2008; 283:19888-94.
    • (2008) J Biol Chem , vol.283 , pp. 19888-19894
    • Rehman, A.O.1    Wang, C.Y.2
  • 33
    • 27544494623 scopus 로고    scopus 로고
    • Upregulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: Role of MEK/ERK signaling pathway-dependent NFkappaB activation
    • Kukreja P, Abdel-Mageed AB, Mondal D, Liu K, Agrawal KC. Upregulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NFkappaB activation. Cancer Res 2005; 65:9891-8.
    • (2005) Cancer Res , vol.65 , pp. 9891-9898
    • Kukreja, P.1    Abdel-Mageed, A.B.2    Mondal, D.3    Liu, K.4    Agrawal, K.C.5
  • 34
    • 34250671989 scopus 로고    scopus 로고
    • Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: A perspective
    • Pullikuth AK, Catling AD. Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective. Cell Signal 2007; 19:1621-32.
    • (2007) Cell Signal , vol.19 , pp. 1621-1632
    • Pullikuth, A.K.1    Catling, A.D.2
  • 35
    • 0030660196 scopus 로고    scopus 로고
    • Syndecans: Multifunctional cell-surface co-receptors
    • Carey DJ. Syndecans: multifunctional cell-surface co-receptors. Biochem J 1997; 327:1-16.
    • (1997) Biochem J , vol.327 , pp. 1-16
    • Carey, D.J.1
  • 37
    • 17444392059 scopus 로고    scopus 로고
    • Syndecan-4 is a signaling molecule for stromal cell-derived factor-1 (SDF-1)/ CXCL12
    • Charnaux N, Brule S, Hamon M, Chaigneau T, Saffar L, Prost C, et al. Syndecan-4 is a signaling molecule for stromal cell-derived factor-1 (SDF-1)/ CXCL12. FEBS J 2005; 272:1937-51.
    • (2005) FEBS J , vol.272 , pp. 1937-1951
    • Charnaux, N.1    Brule, S.2    Hamon, M.3    Chaigneau, T.4    Saffar, L.5    Prost, C.6
  • 38
    • 67749098104 scopus 로고    scopus 로고
    • Chlamydomonas swims with two "gears" in a eukaryotic version of run-and-tumble locomotion
    • Polin M, Tuval I, Drescher K, Gollub JP, Goldstein RE. Chlamydomonas swims with two "gears" in a eukaryotic version of run-and-tumble locomotion. Science 2009; 325:487-90.
    • (2009) Science , vol.325 , pp. 487-490
    • Polin, M.1    Tuval, I.2    Drescher, K.3    Gollub, J.P.4    Goldstein, R.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.