Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency

Blood

Volumn 96, Issue 5, 2000, Pages 1646-1654

  Williams, D A ^a   Tao, W ^a   Yang, F ^a   Kim, C ^a   Gu, Y ^a   Mansfield, P ^a   Levine, J E ^a   Petryniak, B ^a   Derrow, C W ^a   Harris, C ^a   Jia, B ^a   Zheng, Y ^a   Ambruso, D R ^a   Lowe, J B ^a   Atkinson, S J ^a   Dinauer, M C ^a   Boxer, L ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; F ACTIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GUANOSINE TRIPHOSPHATASE; INTEGRIN; MUTANT PROTEIN; NUCLEOTIDE BINDING PROTEIN; PROTEIN G; RAC PROTEIN; RECOMBINANT PROTEIN; RHO FACTOR; VIRUS VECTOR;

ARTICLE; BASE MISPAIRING; CELL FUNCTION; HEMATOPOIETIC SYSTEM; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MOLECULAR CLONING; NEUTROPHIL; PHAGOCYTE; PRIORITY JOURNAL;

3T3 CELLS; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; DNA MUTATIONAL ANALYSIS; DNA, COMPLEMENTARY; GENES, DOMINANT; GREEN FLUORESCENT PROTEINS; GUANOSINE TRIPHOSPHATE; HEMATOPOIESIS; HUMANS; INFANT; LEUKOCYTOSIS; LUMINESCENT PROTEINS; MALE; MICE; MICROSCOPY, FLUORESCENCE; MUTATION; NEUTROPHILS; PHAGOCYTES; POINT MUTATION; PROTEIN BINDING; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; SUPEROXIDES;

EID: 0034283717     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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