Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac

Infection and Immunity

Volumn 70, Issue 8, 2002, Pages 4053-4058

  Lerm, Maria ^a   Pop, Marius ^a   Fritz, Gerhard ^a   Aktories, Klaus ^a   Schmidt, Gudula ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN; CYTOTOXIC NECROTIZING FACTOR 1; GLUTAMINE; GUANOSINE TRIPHOSPHATE; MESSENGER RNA; PROTEASOME; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CYTOTOXICITY; DEAMINATION; FILOPODIUM; HUMAN; HUMAN CELL; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN STRUCTURE; STRESS;

ACETYLCYSTEINE; BACTERIAL TOXINS; CDC42 GTP-BINDING PROTEIN; CELL LINE; CYSTEINE PROTEINASE INHIBITORS; CYTOTOXINS; ENZYME ACTIVATION; ESCHERICHIA COLI PROTEINS; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 0036070562     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.8.4053-4058.2002     Document Type: Article

References (29)

1. GTPases targeted by bacterial toxins
2. Effectors for the Rho GTPases
3. Neosynthesis and activation of Rho by Escherichia coli cytotoxic necrotizing factor (CNF1) reverse cytopathic effects of ADP-ribosylated Rho
4. RhoB is stabilized by transforming growth factor β and antagonizes transcriptional activation
5. Lactacystin, proteasome function and cell fate
6. N-acetylcysteine protects epithelial cells against the oxidative imbalance due to Clostridium difficile toxin
7. Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine
8. Modulation of actin cytoskeleton by salmonella GTPase activating protein SptP
9. The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases
10. Proteasomal degradation of Smad1 induced by bone morphogenetic proteins
11. Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
12. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
13. Glucosylation of Rho proteins by Clostridium difficile toxin B
14. Modes of regulation of ubiquitin-mediated protein degradation
15. Bacterial protein toxins targeting Rho GTPases
16. Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1 (CNF1): Activation of c-Jun-N-terminal kinase in HeLa cells
17. Rho GTPases
18. Activation of rat liver phospholipase D by the small GTP-binding protein RhoA
19. Effect of Rho and ADP-ribosylation factor GTPases on phospholipase D activity in intact human adenocarcinoma A549 cells
20. ATP-dependent inactivation and sequestration of ornithine decarboxylase by the 26S proteasome are prerequisites for degradation
21. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
22. Gene expression of the small GTP-binding proteins RhoA, RhoB, Rac1, and Cdc42 in adult rat brain
23. Targeting of substrates to the 26S proteasome
24. Rho: Theme and variations
25. Gln63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor 1
26. The small GTPase Rac interacts with ubiquitination complex proteins Cullin-1 and Cdc23
27. Regulation of phospholipase D in HL60 cells
28. GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: A mechanism for disruption of actin microfilament structure
29. Rac1 mediates type I collagen-dependent MMP-2 activation