Reduced expression of the rock inhibitor rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Belgiovine, Cristina ^a   Frapolli, Roberta ^b   Bonezzi, Katiuscia ^b   Chiodi, Ilaria ^a   Favero, Francesco ^c   Mello Grand, Maurizia ^c   dei Tos, Angelo P ^d   Giulotto, Elena ^e   Taraboletti, Giulia ^b   D'Incalci, Maurizio ^b   Mondello, Chiara ^a  

^a CNR   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c Laboratory of Cancer Genomics   (Italy)

^d OSPEDALE CA FONCELLO   (Italy)

^e UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; MATRIX METALLOPROTEINASE; PROTEIN RND3; PROTEINASE INHIBITOR; REGULATOR PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RND3 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT TRANSFORMATION; MESENCHYME CELL; METASTASIS; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; SARCOMA; SARCOMA CELL; ANIMAL; CELL LINE; CELL MOTION; CELL SHAPE; CELL STRAIN 3T3; DNA MICROARRAY; EXPERIMENTAL NEOPLASM; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; MESODERM; METABOLISM; MOUSE MUTANT; NUDE MOUSE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APSEUDES; MUS;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CELL MOVEMENT; CELL SHAPE; FEMALE; FIBROBLASTS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; MATRIX METALLOPROTEINASES; MESODERM; MICE; MICE, NUDE; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASMS, EXPERIMENTAL; NIH 3T3 CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO GTP-BINDING PROTEINS;

EID: 78649771814     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014154     Document Type: Article

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