RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility

Journal of Biological Chemistry

Volumn 287, Issue 17, 2012, Pages 13752-13760

  Yu, Jianxiu ^a   Zhang, Dongyun ^a   Liu, Jinyi ^a   Li, Jingxia ^a   Yu, Yonghui ^a   Wu, Xue Ru ^a   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN POLYMERIZATION; BINDING ACTIVITIES; BINDING AFFINITIES; CANCER CELLS; CELL MOTILITY; COMPLEX FORMATIONS; CYTOSKELETONS; GTPASES; SUMOYLATION; X-LINKED INHIBITOR OF APOPTOSIS;

BINDING ENERGY; CYTOLOGY; DISSOCIATION; POLYMERIZATION; PROTEINS;

CELLS;

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; LYSINE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ACTIN POLYMERIZATION; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CANCER INVASION; CELL MOTILITY; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION; SUMOYLATION;

CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; HUMANS; LYSINE; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASMS; RHO GTP-BINDING PROTEINS; SUMOYLATION; WOUND HEALING; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84859950102     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.337469     Document Type: Article

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