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Volumn 125, Issue 13, 2012, Pages 3015-3024

Deconstructing the third dimension-how 3D culture microenvironments alter cellular cues

Author keywords

3D culture models; Cell adhesion; Dimensionality; Mechanotransduction; Microenvironment; Soluble factors

Indexed keywords

COLLAGEN; FIBRONECTIN; NANOFIBER; NITRIC OXIDE; OXYGEN; SCATTER FACTOR; SILICONE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84867887350     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.079509     Document Type: Note
Times cited : (1389)

References (126)
  • 1
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • Adams, R. H. and Alitalo, K. (2007). Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 8, 464-478.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 464-478
    • Adams, R.H.1    Alitalo, K.2
  • 2
    • 24644466511 scopus 로고    scopus 로고
    • Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts
    • Amatangelo, M. D., Bassi, D. E., Klein-Szanto, A. J. P. and Cukierman, E. (2005). Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts. Am. J. Pathol. 167, 475-488.
    • (2005) Am. J. Pathol. , vol.167 , pp. 475-488
    • Amatangelo, M.D.1    Bassi, D.E.2    Klein-Szanto, A.J.P.3    Cukierman, E.4
  • 3
    • 77956230558 scopus 로고    scopus 로고
    • The interaction of cells and bacteria with surfaces structured at the nanometre scale
    • Anselme, K., Davidson, P., Popa, A. M., Giazzon, M., Liley, M. and Ploux, L. (2010). The interaction of cells and bacteria with surfaces structured at the nanometre scale. Acta Biomater. 6, 3824-3846.
    • (2010) Acta Biomater , vol.6 , pp. 3824-3846
    • Anselme, K.1    Davidson, P.2    Popa, A.M.3    Giazzon, M.4    Liley, M.5    Ploux, L.6
  • 5
    • 0024600971 scopus 로고
    • Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules
    • Bashkin, P., Doctrow, S., Klagsbrun, M., Svahn, C. M., Folkman, J. and Vlodavsky, I. (1989). Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules. Biochemistry 28, 1737-1743.
    • (1989) Biochemistry , vol.28 , pp. 1737-1743
    • Bashkin, P.1    Doctrow, S.2    Klagsbrun, M.3    Svahn, C.M.4    Folkman, J.5    Vlodavsky, I.6
  • 6
    • 23744432972 scopus 로고    scopus 로고
    • Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression
    • Beacham, D. A. and Cukierman, E. (2005). Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression. Semin. Cancer Biol. 15, 329-341.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 329-341
    • Beacham, D.A.1    Cukierman, E.2
  • 7
    • 43249096789 scopus 로고    scopus 로고
    • Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts
    • Beacham, D. A., Amatangelo, M. D., and Cukierman, E. (2007). Preparation of Extracellular Matrices Produced by Cultured and Primary Fibroblasts. Curr. Protoc. Cell Biol. 33, 10.9.1-10.9.21.
    • (2007) Curr. Protoc. Cell Biol. , vol.33
    • Beacham, D.A.1    Amatangelo, M.D.2    Cukierman, E.3
  • 8
    • 11144224316 scopus 로고    scopus 로고
    • Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors
    • Beningo, K. A., Dembo, M. and Wang, Y. L. (2004). Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors. Proc. Natl. Acad. Sci. USA 101, 18024-18029.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 18024-18029
    • Beningo, K.A.1    Dembo, M.2    Wang, Y.L.3
  • 9
    • 0020369710 scopus 로고
    • Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels
    • Benya, P. D. and Shaffer, J. D. (1982). Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30, 215-224.
    • (1982) Cell , vol.30 , pp. 215-224
    • Benya, P.D.1    Shaffer, J.D.2
  • 10
    • 70349934306 scopus 로고    scopus 로고
    • Engineering substrate topography at the micro- and nanoscale to control cell function
    • Bettinger, C. J., Langer, R. and Borenstein, J. T. (2009). Engineering substrate topography at the micro- and nanoscale to control cell function. Angew. Chem. Int. Ed. Engl. 48, 5406-5415.
    • (2009) Angew. Chem. Int. Ed. Engl. , vol.48 , pp. 5406-5415
    • Bettinger, C.J.1    Langer, R.2    Borenstein, J.T.3
  • 11
    • 0020456385 scopus 로고
    • How does the extracellular matrix direct gene expression? J
    • Bissell, M. J., Hall, H. G. and Parry, G. (1982). How does the extracellular matrix direct gene expression? J. Theor. Biol. 99, 31-68.
    • (1982) Theor. Biol. , vol.99 , pp. 31-68
    • Bissell, M.J.1    Hall, H.G.2    Parry, G.3
  • 13
    • 0037418473 scopus 로고    scopus 로고
    • Geometric determinants of directional cell motility revealed using microcontact printing
    • Brock, A., Chang, E., Ho, C.-C., LeDuc, P., Jiang, X., Whitesides, G. M. and Ingber, D. E. (2003). Geometric determinants of directional cell motility revealed using microcontact printing. Langmuir 19, 1611-1617.
    • (2003) Langmuir , vol.19 , pp. 1611-1617
    • Brock, A.1    Chang, E.2    Ho, C.-C.3    LeDuc, P.4    Jiang, X.5    Whitesides, G.M.6    Ingber, D.E.7
  • 14
    • 0036342297 scopus 로고    scopus 로고
    • Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering
    • Burdick, J. A. and Anseth, K. S. (2002). Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 23, 4315-4323.
    • (2002) Biomaterials , vol.23 , pp. 4315-4323
    • Burdick, J.A.1    Anseth, K.S.2
  • 15
    • 0024150623 scopus 로고
    • Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton
    • Burridge, K., Fath, K., Kelly, T., Nuckolls, G. and Turner, C. (1988). Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol. 4, 487-525.
    • (1988) Annu. Rev. Cell Biol. , vol.4 , pp. 487-525
    • Burridge, K.1    Fath, K.2    Kelly, T.3    Nuckolls, G.4    Turner, C.5
  • 16
    • 56349169536 scopus 로고    scopus 로고
    • Mechanotransduction - a field pulling together? J
    • Chen, C. S. (2008). Mechanotransduction - a field pulling together? J. Cell Sci. 121, 3285-3292.
    • (2008) Cell Sci , vol.121 , pp. 3285-3292
    • Chen, C.S.1
  • 18
    • 33751339324 scopus 로고    scopus 로고
    • Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels
    • Connelly, J. T., Garci{dotless}́a, A. J. and Levenston, M. E. (2007). Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels. Biomaterials 28, 1071-1083.
    • (2007) Biomaterials , vol.28 , pp. 1071-1083
    • Connelly, J.T.1    García, A.J.2    Levenston, M.E.3
  • 19
    • 0035941075 scopus 로고    scopus 로고
    • Taking cellmatrix adhesions to the third dimension
    • Cukierman, E., Pankov, R., Stevens, D. R. and Yamada, K. M. (2001). Taking cellmatrix adhesions to the third dimension. Science 294, 1708-1712.
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 20
    • 3543002226 scopus 로고    scopus 로고
    • Use of nanotopography to study mechanotransduction in fibroblasts-methods and perspectives
    • Dalby, M. J., Riehle, M. O., Sutherland, D. S., Agheli, H. and Curtis, A. S. G. (2004). Use of nanotopography to study mechanotransduction in fibroblasts-methods and perspectives. Eur. J. Cell Biol. 83, 159-169.
    • (2004) Eur. J. Cell Biol. , vol.83 , pp. 159-169
    • Dalby, M.J.1    Riehle, M.O.2    Sutherland, D.S.3    Agheli, H.4    Curtis, A.S.G.5
  • 21
    • 0037020196 scopus 로고    scopus 로고
    • The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
    • Debnath, J., Mills, K. R., Collins, N. L., Reginato, M. J., Muthuswamy, S. K. and Brugge, J. S. (2002). The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 111, 29-40.
    • (2002) Cell , vol.111 , pp. 29-40
    • Debnath, J.1    Mills, K.R.2    Collins, N.L.3    Reginato, M.J.4    Muthuswamy, S.K.5    Brugge, J.S.6
  • 22
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath, J., Muthuswamy, S. K. and Brugge, J. S. (2003). Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30, 256-268.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 23
    • 68849096820 scopus 로고    scopus 로고
    • Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments
    • DeForest, C. A., Polizzotti, B. D. and Anseth, K. S. (2009). Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments. Nat. Mater. 8, 659-664.
    • (2009) Nat. Mater. , vol.8 , pp. 659-664
    • DeForest, C.A.1    Polizzotti, B.D.2    Anseth, K.S.3
  • 24
    • 0033066120 scopus 로고    scopus 로고
    • Stresses at the cell-to-substrate interface during locomotion of fibroblasts
    • Dembo, M. and Wang, Y.-L. (1999). Stresses at the cell-to-substrate interface during locomotion of fibroblasts. Biophys. J. 76, 2307-2316.
    • (1999) Biophys. J. , vol.76 , pp. 2307-2316
    • Dembo, M.1    Wang, Y.-L.2
  • 25
    • 66349108868 scopus 로고    scopus 로고
    • Cell polarity triggered by cell-cell adhesion via E-cadherin
    • Desai, R. A., Gao, L., Raghavan, S., Liu, W. F. and Chen, C. S. (2009). Cell polarity triggered by cell-cell adhesion via E-cadherin. J. Cell Sci. 122, 905-911.
    • (2009) J. Cell Sci. , vol.122 , pp. 905-911
    • Desai, R.A.1    Gao, L.2    Raghavan, S.3    Liu, W.F.4    Chen, C.S.5
  • 26
    • 61449181308 scopus 로고    scopus 로고
    • Onedimensional topography underlies three-dimensional fibrillar cell migration
    • Doyle, A. D., Wang, F. W., Matsumoto, K. and Yamada, K. M. (2009). Onedimensional topography underlies three-dimensional fibrillar cell migration. J. Cell Biol. 184, 481-490.
    • (2009) J. Cell Biol. , vol.184 , pp. 481-490
    • Doyle, A.D.1    Wang, F.W.2    Matsumoto, K.3    Yamada, K.M.4
  • 27
    • 0024502767 scopus 로고
    • Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration
    • Dunn, J. C., Yarmush, M. L., Koebe, H. G. and Tompkins, R. G. (1989). Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB J. 3, 174-177.
    • (1989) FASEB J , vol.3 , pp. 174-177
    • Dunn, J.C.1    Yarmush, M.L.2    Koebe, H.G.3    Tompkins, R.G.4
  • 28
    • 0017654607 scopus 로고
    • Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes
    • Emerman, J. T. and Pitelka, D. R. (1977). Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes. In Vitro 13, 316-328.
    • (1977) In Vitro , vol.13 , pp. 316-328
    • Emerman, J.T.1    Pitelka, D.R.2
  • 29
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • Engler, A. J., Sen, S., Sweeney, H. L. and Discher, D. E. (2006). Matrix elasticity directs stem cell lineage specification. Cell 126, 677-689.
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 30
    • 79960277917 scopus 로고    scopus 로고
    • A hitchhiker's guide to mechanobiology
    • Eyckmans, J., Boudou, T., Yu, X. and Chen, C. S. (2011). A hitchhiker's guide to mechanobiology. Dev. Cell 21, 35-47.
    • (2011) Dev. Cell , vol.21 , pp. 35-47
    • Eyckmans, J.1    Boudou, T.2    Yu, X.3    Chen, C.S.4
  • 32
    • 77956318381 scopus 로고    scopus 로고
    • Mechanical regulation of cell function with geometrically modulated elastomeric substrates
    • Fu, J., Wang, Y.-K., Yang, M. T., Desai, R. A., Yu, X., Liu, Z. and Chen, C. S. (2010). Mechanical regulation of cell function with geometrically modulated elastomeric substrates. Nat. Methods 7, 733-736.
    • (2010) Nat. Methods , vol.7 , pp. 733-736
    • Fu, J.1    Wang, Y.-K.2    Yang, M.T.3    Desai, R.A.4    Yu, X.5    Liu, Z.6    Chen, C.S.7
  • 33
    • 77950584190 scopus 로고    scopus 로고
    • Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin
    • Gao, L., McBeath, R. and Chen, C. S. (2010). Stem cell shape regulates a chondrogenic versus myogenic fate through Rac1 and N-cadherin. Stem Cells 28, 564-572.
    • (2010) Stem Cells , vol.28 , pp. 564-572
    • Gao, L.1    McBeath, R.2    Chen, C.S.3
  • 38
    • 33644529130 scopus 로고    scopus 로고
    • Capturing complex 3D tissue physiology in vitro
    • Griffith, L. G. and Swartz, M. A. (2006). Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 7, 211-224.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 211-224
    • Griffith, L.G.1    Swartz, M.A.2
  • 39
    • 0038738331 scopus 로고    scopus 로고
    • Fibroblast biology in three-dimensional collagen matrices
    • Grinnell, F. (2003). Fibroblast biology in three-dimensional collagen matrices. Trends Cell Biol. 13, 264-269.
    • (2003) Trends Cell Biol , vol.13 , pp. 264-269
    • Grinnell, F.1
  • 40
    • 0037328762 scopus 로고    scopus 로고
    • Dendritic fibroblasts in three-dimensional collagen matrices
    • Grinnell, F., Ho, C.-H., Tamariz, E., Lee, D. J. and Skuta, G. (2003). Dendritic fibroblasts in three-dimensional collagen matrices. Mol. Biol. Cell 14, 384-395.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 384-395
    • Grinnell, F.1    Ho, C.-H.2    Tamariz, E.3    Lee, D.J.4    Skuta, G.5
  • 41
    • 0035950105 scopus 로고    scopus 로고
    • Morphogen gradient interpretation
    • Gurdon, J. B. and Bourillot, P. Y. (2001). Morphogen gradient interpretation. Nature 413, 797-803
    • (2001) Nature , vol.413 , pp. 797-803
    • Gurdon, J.B.1    Bourillot, P.Y.2
  • 42
    • 80053925801 scopus 로고    scopus 로고
    • Cell-matrix adhesions in 3D
    • Harunaga, J. S. and Yamada, K. M. (2011). Cell-matrix adhesions in 3D. Matrix Biol. 30, 363-368.
    • (2011) Matrix Biol , vol.30 , pp. 363-368
    • Harunaga, J.S.1    Yamada, K.M.2
  • 43
    • 80755139367 scopus 로고    scopus 로고
    • Fiber stretch and reorientation modulates mesenchymal stem cell morphology and fibrous gene expression on oriented nanofibrous microenvironments
    • Heo, S.-J., Nerurkar, N. L., Baker, B. M., Shin, J.-W., Elliott, D. M. and Mauck, R. L. (2011). Fiber stretch and reorientation modulates mesenchymal stem cell morphology and fibrous gene expression on oriented nanofibrous microenvironments. Ann. Biomed. Eng. 39, 2780-2790.
    • (2011) Ann. Biomed. Eng. , vol.39 , pp. 2780-2790
    • Heo, S.-J.1    Nerurkar, N.L.2    Baker, B.M.3    Shin, J.-W.4    Elliott, D.M.5    Mauck, R.L.6
  • 45
    • 79960637431 scopus 로고    scopus 로고
    • Dynamic molecular processes mediate cellular mechanotransduction
    • Hoffman, B. D., Grashoff, C. and Schwartz, M. A. (2011). Dynamic molecular processes mediate cellular mechanotransduction. Nature 475, 316-323.
    • (2011) Nature , vol.475 , pp. 316-323
    • Hoffman, B.D.1    Grashoff, C.2    Schwartz, M.A.3
  • 46
  • 48
    • 77956399506 scopus 로고    scopus 로고
    • Matrigel: a complex protein mixture required for optimal growth of cell culture
    • Hughes, C. S., Postovit, L. M. and Lajoie, G. A. (2010). Matrigel: a complex protein mixture required for optimal growth of cell culture. Proteomics 10, 1886-1890.
    • (2010) Proteomics , vol.10 , pp. 1886-1890
    • Hughes, C.S.1    Postovit, L.M.2    Lajoie, G.A.3
  • 50
    • 0028918625 scopus 로고
    • Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells
    • Keely, P. J., Fong, A. M., Zutter, M. M. and Santoro, S. A. (1995). Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells. J. Cell Sci. 108, 595-607.
    • (1995) J. Cell Sci. , vol.108 , pp. 595-607
    • Keely, P.J.1    Fong, A.M.2    Zutter, M.M.3    Santoro, S.A.4
  • 51
    • 77956185209 scopus 로고    scopus 로고
    • Patterning network structure to spatially control cellular remodeling and stem cell fate within 3-dimensional hydrogels
    • Khetan, S. and Burdick, J. A. (2010). Patterning network structure to spatially control cellular remodeling and stem cell fate within 3-dimensional hydrogels. Biomaterials 31, 8228-8234.
    • (2010) Biomaterials , vol.31 , pp. 8228-8234
    • Khetan, S.1    Burdick, J.A.2
  • 52
    • 77950427004 scopus 로고    scopus 로고
    • Geometric cues for directing the differentiation of mesenchymal stem cells
    • Kilian, K. A., Bugarija, B., Lahn, B. T. and Mrksich, M. (2010). Geometric cues for directing the differentiation of mesenchymal stem cells. Proc. Natl. Acad. Sci. USA 107, 4872-4877.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 4872-4877
    • Kilian, K.A.1    Bugarija, B.2    Lahn, B.T.3    Mrksich, M.4
  • 53
    • 78149268198 scopus 로고    scopus 로고
    • Biological applications of microfluidic gradient devices
    • Kim, S., Kim, H. J. and Jeon, N. L. (2010). Biological applications of microfluidic gradient devices. Integr Biol (Camb) 2, 584-603.
    • (2010) Integr Biol (Camb) , vol.2 , pp. 584-603
    • Kim, S.1    Kim, H.J.2    Jeon, N.L.3
  • 54
    • 0037162463 scopus 로고    scopus 로고
    • Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair
    • Kisiday, J., Jin, M., Kurz, B., Hung, H., Semino, C., Zhang, S. and Grodzinsky, A. J. (2002). Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc. Natl. Acad. Sci. USA 99, 9996-10001.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 9996-10001
    • Kisiday, J.1    Jin, M.2    Kurz, B.3    Hung, H.4    Semino, C.5    Zhang, S.6    Grodzinsky, A.J.7
  • 56
    • 23744449992 scopus 로고    scopus 로고
    • Matrigel: basement membrane matrix with biological activity
    • Kleinman, H. K. and Martin, G. R. (2005). Matrigel: basement membrane matrix with biological activity. Semin. Cancer Biol. 15, 378-386.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 378-386
    • Kleinman, H.K.1    Martin, G.R.2
  • 57
    • 64249113913 scopus 로고    scopus 로고
    • Photodegradable hydrogels for dynamic tuning of physical and chemical properties
    • Kloxin, A. M., Kasko, A. M., Salinas, C. N. and Anseth, K. S. (2009). Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science 324, 59-63.
    • (2009) Science , vol.324 , pp. 59-63
    • Kloxin, A.M.1    Kasko, A.M.2    Salinas, C.N.3    Anseth, K.S.4
  • 58
    • 78650457713 scopus 로고    scopus 로고
    • Reducing background fluorescence reveals adhesions in 3D matrices
    • author reply 5-7
    • Kubow, K. E. and Horwitz, A. R. (2011). Reducing background fluorescence reveals adhesions in 3D matrices. Nat. Cell Biol. 13, 3-5, author reply 5-7.
    • (2011) Nat. Cell Biol , vol.13 , pp. 3-5
    • Kubow, K.E.1    Horwitz, A.R.2
  • 59
    • 33750838708 scopus 로고    scopus 로고
    • Anisotropic mechanosensing by mesenchymal stem cells
    • Kurpinski, K., Chu, J., Hashi, C. and Li, S. (2006). Anisotropic mechanosensing by mesenchymal stem cells. Proc. Natl. Acad. Sci. USA 103, 16095-16100.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16095-16100
    • Kurpinski, K.1    Chu, J.2    Hashi, C.3    Li, S.4
  • 60
    • 0033808163 scopus 로고    scopus 로고
    • The chondrocyte cytoskeleton in mature articular cartilage: structure and distribution of actin, tubulin, and vimentin filaments
    • Langelier, E., Suetterlin, R., Hoemann, C. D., Aebi, U. and Buschmann, M. D. (2000). The chondrocyte cytoskeleton in mature articular cartilage: structure and distribution of actin, tubulin, and vimentin filaments. J. Histochem. Cytochem. 48, 1307-1320.
    • (2000) J. Histochem. Cytochem. , vol.48 , pp. 1307-1320
    • Langelier, E.1    Suetterlin, R.2    Hoemann, C.D.3    Aebi, U.4    Buschmann, M.D.5
  • 61
    • 1842484779 scopus 로고    scopus 로고
    • Designing materials for biology and medicine
    • Langer, R. and Tirrell, D. A. (2004). Designing materials for biology and medicine. Nature 428, 487-492.
    • (2004) Nature , vol.428 , pp. 487-492
    • Langer, R.1    Tirrell, D.A.2
  • 63
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: a physically integrated molecular process
    • Lauffenburger, D. A. and Horwitz, A. F. (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-369.
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 64
    • 0021331570 scopus 로고
    • Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata
    • Lee, E. Y., Parry, G. and Bissell, M. J. (1984). Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata. J. Cell Biol. 98, 146-155.
    • (1984) J. Cell Biol. , vol.98 , pp. 146-155
    • Lee, E.Y.1    Parry, G.2    Bissell, M.J.3
  • 65
    • 42749097087 scopus 로고    scopus 로고
    • Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration
    • Lee, S.-H., Moon, J. J. and West, J. L. (2008). Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration. Biomaterials 29, 2962-2968.
    • (2008) Biomaterials , vol.29 , pp. 2962-2968
    • Lee, S.-H.1    Moon, J.J.2    West, J.L.3
  • 66
    • 78649717029 scopus 로고    scopus 로고
    • Measurement of mechanical tractions exerted by cells in threedimensional matrices
    • Legant, W. R., Miller, J. S., Blakely, B. L., Cohen, D. M., Genin, G. M. and Chen, C. S. (2010). Measurement of mechanical tractions exerted by cells in threedimensional matrices. Nat. Methods 7, 969-971.
    • (2010) Nat. Methods , vol.7 , pp. 969-971
    • Legant, W.R.1    Miller, J.S.2    Blakely, B.L.3    Cohen, D.M.4    Genin, G.M.5    Chen, C.S.6
  • 68
    • 19644367664 scopus 로고    scopus 로고
    • Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
    • Lutolf, M. P. and Hubbell, J. A. (2005). Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat. Biotechnol. 23, 47-55.
    • (2005) Nat. Biotechnol. , vol.23 , pp. 47-55
    • Lutolf, M.P.1    Hubbell, J.A.2
  • 70
    • 0026329259 scopus 로고
    • Proteoglycan and collagen synthesis are correlated with actin organization in dedifferentiating chondrocytes
    • Mallein-Gerin, F., Garrone, R. and van der Rest, M. (1991). Proteoglycan and collagen synthesis are correlated with actin organization in dedifferentiating chondrocytes. Eur. J. Cell Biol. 56, 364-373.
    • (1991) Eur. J. Cell Biol. , vol.56 , pp. 364-373
    • Mallein-Gerin, F.1    Garrone, R.2    van der Rest, M.3
  • 71
    • 33845869572 scopus 로고    scopus 로고
    • Sharp boundaries of Dpp signalling trigger local cell death required for Drosophila leg morphogenesis
    • Manjoń, C., Sańchez-Herrero, E. and Suzanne, M. (2007). Sharp boundaries of Dpp signalling trigger local cell death required for Drosophila leg morphogenesis. Nat. Cell Biol. 9, 57-63.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 57-63
    • Manjoń, C.1    Sańchez-Herrero, E.2    Suzanne, M.3
  • 72
    • 0035889827 scopus 로고    scopus 로고
    • Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering
    • Mann, B. K., Gobin, A. S., Tsai, A. T., Schmedlen, R. H. and West, J. L. (2001). Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. Biomaterials 22, 3045-3051.
    • (2001) Biomaterials , vol.22 , pp. 3045-3051
    • Mann, B.K.1    Gobin, A.S.2    Tsai, A.T.3    Schmedlen, R.H.4    West, J.L.5
  • 75
    • 1842426730 scopus 로고    scopus 로고
    • Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
    • McBeath, R., Pirone, D. M., Nelson, C. M., Bhadriraju, K. and Chen, C. S. (2004). Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell 6, 483-495.
    • (2004) Dev. Cell , vol.6 , pp. 483-495
    • McBeath, R.1    Pirone, D.M.2    Nelson, C.M.3    Bhadriraju, K.4    Chen, C.S.5
  • 76
    • 33750619877 scopus 로고    scopus 로고
    • Potential for control of signaling pathways via cell size and shape
    • Meyers, J., Craig, J. and Odde, D. J. (2006). Potential for control of signaling pathways via cell size and shape. Curr. Biol. 16, 1685-1693.
    • (2006) Curr. Biol. , vol.16 , pp. 1685-1693
    • Meyers, J.1    Craig, J.2    Odde, D.J.3
  • 78
    • 38349046975 scopus 로고    scopus 로고
    • ADF/cofilin family proteins control formation of oriented actin-filament bundles in the cell body to trigger fibroblast polarization
    • Mseka, T., Bamburg, J. R. and Cramer, L. P. (2007). ADF/cofilin family proteins control formation of oriented actin-filament bundles in the cell body to trigger fibroblast polarization. J. Cell Sci. 120, 4332-4344.
    • (2007) J. Cell Sci. , vol.120 , pp. 4332-4344
    • Mseka, T.1    Bamburg, J.R.2    Cramer, L.P.3
  • 79
    • 0030697292 scopus 로고    scopus 로고
    • Three-dimensional cell cultures: from molecular mechanisms to clinical applications
    • Mueller-Klieser, W. (1997). Three-dimensional cell cultures: from molecular mechanisms to clinical applications. Am. J. Physiol. 273, C1109-C1123.
    • (1997) Am. J. Physiol. , vol.273
    • Mueller-Klieser, W.1
  • 80
    • 78049426449 scopus 로고    scopus 로고
    • Mechanotopographic modulation of stem cell nuclear shape on nanofibrous scaffolds
    • Nathan, A. S., Baker, B. M., Nerurkar, N. L. and Mauck, R. L. (2011). Mechanotopographic modulation of stem cell nuclear shape on nanofibrous scaffolds. Acta Biomater. 7, 57-66.
    • (2011) Acta Biomater , vol.7 , pp. 57-66
    • Nathan, A.S.1    Baker, B.M.2    Nerurkar, N.L.3    Mauck, R.L.4
  • 81
    • 33749992857 scopus 로고    scopus 로고
    • Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures
    • Nelson, C. M., Vanduijn, M. M., Inman, J. L., Fletcher, D. A. and Bissell, M. J. (2006). Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science 314, 298-300.
    • (2006) Science , vol.314 , pp. 298-300
    • Nelson, C.M.1    Vanduijn, M.M.2    Inman, J.L.3    Fletcher, D.A.4    Bissell, M.J.5
  • 82
    • 77649264979 scopus 로고    scopus 로고
    • Enabling tools for engineering collagenous tissues integrating bioreactors, intravital imaging, and biomechanical modeling
    • Niklason, L. E., Yeh, A. T., Calle, E. A., Bai, Y., Valenti{dotless}́n, A. and Humphrey, J. D. (2010). Enabling tools for engineering collagenous tissues integrating bioreactors, intravital imaging, and biomechanical modeling. Proc. Natl. Acad. Sci. USA 107, 3335-3339.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 3335-3339
    • Niklason, L.E.1    Yeh, A.T.2    Calle, E.A.3    Bai, Y.4    Valentín, A.5    Humphrey, J.D.6
  • 84
    • 34547221505 scopus 로고    scopus 로고
    • Understanding the biology of angiogenesis: review of the most important molecular mechanisms
    • Otrock, Z. K., Mahfouz, R. A. R., Makarem, J. A. and Shamseddine, A. I. (2007). Understanding the biology of angiogenesis: review of the most important molecular mechanisms. Blood Cells Mol. Dis. 39, 212-220.
    • (2007) Blood Cells Mol. Dis. , vol.39 , pp. 212-220
    • Otrock, Z.K.1    Mahfouz, R.A.R.2    Makarem, J.A.3    Shamseddine, A.I.4
  • 85
    • 0026082034 scopus 로고
    • Transforming growth factor beta type 1 binds to collagen IV of basement membrane matrix: implications for development
    • Paralkar, V. M., Vukicevic, S. and Reddi, A. H. (1991). Transforming growth factor beta type 1 binds to collagen IV of basement membrane matrix: implications for development. Dev. Biol. 143, 303-308.
    • (1991) Dev. Biol. , vol.143 , pp. 303-308
    • Paralkar, V.M.1    Vukicevic, S.2    Reddi, A.H.3
  • 86
    • 0027751890 scopus 로고
    • The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
    • Park, J. E., Keller, G. A. and Ferrara, N. (1993). The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol. Biol. Cell 4, 1317-1326.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1317-1326
    • Park, J.E.1    Keller, G.A.2    Ferrara, N.3
  • 87
    • 0021915080 scopus 로고
    • Collagenous substrata regulate the nature and distribution of glycosaminoglycans produced by differentiated cultures of mouse mammary epithelial cells
    • Parry, G., Lee, E. Y.-H., Farson, D., Koval, M. and Bissell, M. J. (1985). Collagenous substrata regulate the nature and distribution of glycosaminoglycans produced by differentiated cultures of mouse mammary epithelial cells. Exp. Cell Res. 156, 487-499.
    • (1985) Exp. Cell Res. , vol.156 , pp. 487-499
    • Parry, G.1    Lee, E.-H.2    Farson, D.3    Koval, M.4    Bissell, M.J.5
  • 89
    • 79953670987 scopus 로고    scopus 로고
    • Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness
    • Pathak, A. and Kumar, S. (2011). Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness. Integr Biol (Camb) 3, 267-278.
    • (2011) Integr Biol (Camb) , vol.3 , pp. 267-278
    • Pathak, A.1    Kumar, S.2
  • 90
    • 0026738947 scopus 로고
    • Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
    • Petersen, O. W., Rønnov-Jessen, L., Howlett, A. R. and Bissell, M. J. (1992). Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natl. Acad. Sci. USA 89, 9064-9068.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9064-9068
    • Petersen, O.W.1    Rønnov-Jessen, L.2    Howlett, A.R.3    Bissell, M.J.4
  • 93
    • 0034711410 scopus 로고    scopus 로고
    • From micro- to nanofabrication with soft materials
    • Quake, S. R. and Scherer, A. (2000). From micro- to nanofabrication with soft materials. Science 290, 1536-1540.
    • (2000) Science , vol.290 , pp. 1536-1540
    • Quake, S.R.1    Scherer, A.2
  • 94
    • 23244447869 scopus 로고    scopus 로고
    • Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration
    • Raeber, G. P., Lutolf, M. P. and Hubbell, J. A. (2005). Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration. Biophys. J. 89, 1374-1388.
    • (2005) Biophys. J. , vol.89 , pp. 1374-1388
    • Raeber, G.P.1    Lutolf, M.P.2    Hubbell, J.A.3
  • 95
    • 77956917822 scopus 로고    scopus 로고
    • Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis
    • Raghavan, S., Shen, C. J., Desai, R. A., Sniadecki, N. J., Nelson, C. M. and Chen, C. S. (2010). Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis. J. Cell Sci. 123, 2877-2883.
    • (2010) J. Cell Sci. , vol.123 , pp. 2877-2883
    • Raghavan, S.1    Shen, C.J.2    Desai, R.A.3    Sniadecki, N.J.4    Nelson, C.M.5    Chen, C.S.6
  • 96
    • 0036708471 scopus 로고    scopus 로고
    • Diffusion and convection in collagen gels: implications for transport in the tumor interstitium
    • Ramanujan, S., Pluen, A., McKee, T. D., Brown, E. B., Boucher, Y. and Jain, R. K. (2002). Diffusion and convection in collagen gels: implications for transport in the tumor interstitium. Biophys. J. 83, 1650-1660.
    • (2002) Biophys. J. , vol.83 , pp. 1650-1660
    • Ramanujan, S.1    Pluen, A.2    McKee, T.D.3    Brown, E.B.4    Boucher, Y.5    Jain, R.K.6
  • 97
    • 77956883321 scopus 로고    scopus 로고
    • Activation of fibroblasts in cancer stroma
    • Räsänen, K. and Vaheri, A. (2010). Activation of fibroblasts in cancer stroma. Exp. Cell Res. 316, 2713-2722.
    • (2010) Exp. Cell Res. , vol.316 , pp. 2713-2722
    • Räsänen, K.1    Vaheri, A.2
  • 98
    • 23244464968 scopus 로고    scopus 로고
    • The dynamics and mechanics of endothelial cell spreading
    • Reinhart-King, C. A., Dembo, M. and Hammer, D. A. (2005). The dynamics and mechanics of endothelial cell spreading. Biophys. J. 89, 676-689.
    • (2005) Biophys. J. , vol.89 , pp. 676-689
    • Reinhart-King, C.A.1    Dembo, M.2    Hammer, D.A.3
  • 99
    • 0023666065 scopus 로고
    • Integrins: a family of cell surface receptors
    • Hynes, R. O. (1987). Integrins: a family of cell surface receptors. Cell 48, 549-554.
    • (1987) Cell , vol.48 , pp. 549-554
    • Hynes, R.O.1
  • 101
    • 33645546778 scopus 로고    scopus 로고
    • Signal dynamics in Sonic hedgehog tissue patterning
    • Saha, K. and Schaffer, D. V. (2006). Signal dynamics in Sonic hedgehog tissue patterning. Development 133, 889-900.
    • (2006) Development , vol.133 , pp. 889-900
    • Saha, K.1    Schaffer, D.V.2
  • 102
    • 77949412667 scopus 로고    scopus 로고
    • Restriction of receptor movement alters cellular response: physical force sensing by EphA2
    • Salaita, K., Nair, P. M., Petit, R. S., Neve, R. M., Das, D., Gray, J. W. and Groves, J. T. (2010). Restriction of receptor movement alters cellular response: physical force sensing by EphA2. Science 327, 1380-1385.
    • (2010) Science , vol.327 , pp. 1380-1385
    • Salaita, K.1    Nair, P.M.2    Petit, R.S.3    Neve, R.M.4    Das, D.5    Gray, J.W.6    Groves, J.T.7
  • 106
    • 0038107091 scopus 로고    scopus 로고
    • Epithelial contact guidance on well-defined micro- and nanostructured substrates
    • Teixeira, A. I., Abrams, G. A., Bertics, P. J., Murphy, C. J. and Nealey, P. F. (2003). Epithelial contact guidance on well-defined micro- and nanostructured substrates. J. Cell Sci. 116, 1881-1892.
    • (2003) J. Cell Sci. , vol.116 , pp. 1881-1892
    • Teixeira, A.I.1    Abrams, G.A.2    Bertics, P.J.3    Murphy, C.J.4    Nealey, P.F.5
  • 107
    • 78649740028 scopus 로고    scopus 로고
    • Micropatterning as a tool to decipher cell morphogenesis and functions
    • Théry, M. (2010). Micropatterning as a tool to decipher cell morphogenesis and functions. J. Cell Sci. 123, 4201-4213.
    • (2010) J. Cell Sci. , vol.123 , pp. 4201-4213
    • Théry, M.1
  • 109
  • 110
    • 0037133313 scopus 로고    scopus 로고
    • Engineering gene expression and protein synthesis by modulation of nuclear shape
    • Thomas, C. H., Collier, J. H., Sfeir, C. S. and Healy, K. E. (2002). Engineering gene expression and protein synthesis by modulation of nuclear shape. Proc. Natl. Acad. Sci. USA 99, 1972-1977.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1972-1977
    • Thomas, C.H.1    Collier, J.H.2    Sfeir, C.S.3    Healy, K.E.4
  • 111
    • 50349091814 scopus 로고    scopus 로고
    • Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus
    • Upton, M. L., Gilchrist, C. L., Guilak, F. and Setton, L. A. (2008). Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus. Biophys. J. 95, 2116-2124.
    • (2008) Biophys. J. , vol.95 , pp. 2116-2124
    • Upton, M.L.1    Gilchrist, C.L.2    Guilak, F.3    Setton, L.A.4
  • 112
  • 114
    • 0017723046 scopus 로고
    • Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture
    • von der Mark, K., Gauss, V., von der Mark, H. and Müller, P. (1977). Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 267, 531-532.
    • (1977) Nature , vol.267 , pp. 531-532
    • von der Mark, K.1    Gauss, V.2    von der Mark, H.3    Müller, P.4
  • 115
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver, V. M., Petersen, O. W., Wang, F., Larabell, C. A., Briand, P., Damsky, C. and Bissell, M. J. (1997). Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol. 137, 231-245.
    • (1997) J. Cell Biol. , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6    Bissell, M.J.7
  • 116
    • 0036726312 scopus 로고    scopus 로고
    • b4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
    • Weaver, V. M., Lelie'vre, S., Lakins, J. N., Chrenek, M. A., Jones, J. C., Giancotti, F., Werb, Z. and Bissell, M. J. (2002). b4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2, 205-216.
    • (2002) Cancer Cell , vol.2 , pp. 205-216
    • Weaver, V.M.1    Lelie'vre, S.2    Lakins, J.N.3    Chrenek, M.A.4    Jones, J.C.5    Giancotti, F.6    Werb, Z.7    Bissell, M.J.8
  • 117
    • 79953136237 scopus 로고    scopus 로고
    • Integrins and cadherins join forces to form adhesive networks
    • Weber, G. F., Bjerke, M. A. and DeSimone, D. W. (2011). Integrins and cadherins join forces to form adhesive networks. J. Cell Sci. 124, 1183-1193.
    • (2011) J. Cell Sci. , vol.124 , pp. 1183-1193
    • Weber, G.F.1    Bjerke, M.A.2    DeSimone, D.W.3
  • 119
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF-b1 from the extracellular matrix
    • Wipff, P.-J., Rifkin, D. B., Meister, J.-J. and Hinz, B. (2007). Myofibroblast contraction activates latent TGF-b1 from the extracellular matrix. J. Cell Biol. 179, 1311-1323.
    • (2007) J. Cell Biol. , vol.179 , pp. 1311-1323
    • Wipff, P.-J.1    Rifkin, D.B.2    Meister, J.-J.3    Hinz, B.4
  • 121
    • 33744956176 scopus 로고    scopus 로고
    • RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner
    • Woods, A. and Beier, F. (2006). RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner. J. Biol. Chem. 281, 13134-13140.
    • (2006) J. Biol. Chem. , vol.281 , pp. 13134-13140
    • Woods, A.1    Beier, F.2
  • 122
    • 15744375543 scopus 로고    scopus 로고
    • RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis
    • Woods, A., Wang, G. and Beier, F. (2005). RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis. J. Biol. Chem. 280, 11626-11634.
    • (2005) J. Biol. Chem. , vol.280 , pp. 11626-11634
    • Woods, A.1    Wang, G.2    Beier, F.3
  • 124
    • 34249794566 scopus 로고    scopus 로고
    • Understanding microchannel culture: parameters involved in soluble factor signaling
    • Yu, H., Alexander, C. M. and Beebe, D. J. (2007). Understanding microchannel culture: parameters involved in soluble factor signaling. Lab Chip 7, 726-730.
    • (2007) Lab Chip , vol.7 , pp. 726-730
    • Yu, H.1    Alexander, C.M.2    Beebe, D.J.3
  • 126
    • 0141765883 scopus 로고    scopus 로고
    • Fabrication of novel biomaterials through molecular self-assembly
    • Zhang, S. (2003). Fabrication of novel biomaterials through molecular self-assembly. Nat. Biotechnol. 21, 1171-1178.
    • (2003) Nat. Biotechnol , vol.21 , pp. 1171-1178
    • Zhang, S.1


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