Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development

Blood

Volumn 112, Issue 5, 2008, Pages 1767-1775

  Guo, Fukun ^a   Cancelas, Jose A ^a   Hildeman, David ^a   Williams, David A ^a   Zheng, Yi ^a,b,c  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c 3333 Burnet Avenue   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; INTERLEUKIN 2; PROTEIN KINASE B; RAC PROTEIN; RAC1 PROTEIN; RAC2 PROTEIN; T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; NEUROPEPTIDE; RAC1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ADHESION; CELL MATURATION; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; ENZYMOLOGY; GENE TARGETING; GENETICS; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; LYMPHOPOIESIS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; GENE TARGETING; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-2; LYMPHOPOIESIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROPEPTIDES; PROTO-ONCOGENE PROTEINS C-AKT; RAC GTP-BINDING PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 52649136968     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-01-132068     Document Type: Article

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