The effect of aging on p38 signaling pathway activity in the mouse liver and in response to ROS generated by 3-nitropropionic acid

Mechanisms of Ageing and Development

Volumn 123, Issue 11, 2002, Pages 1423-1435

  Hsieh, Ching Chyuan ^a   Papaconstantinou, John ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

3 Nitropropionic acid; Aging; MKK3; Mouse liver; Oxidative stress; p38 MAPK

Indexed keywords

3 NITROPROPIONIC ACID; ENZYME ACTIVATOR; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE; THREONINE; 3-NITROPROPIONIC ACID; MAP2K3 PROTEIN, MOUSE; MAP2K6 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRO DERIVATIVE; PROPIONIC ACID DERIVATIVE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN TYROSINE KINASE;

AGING; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; LIVER CYTOSOL; LIVER MITOCHONDRION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECT; LIVER; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

AGING; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; LIVER; MALE; MAP KINASE KINASE 3; MAP KINASE KINASE 6; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NITRO COMPOUNDS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROPIONIC ACIDS; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; THREONINE;

EID: 0036757263     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(02)00084-2     Document Type: Article

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