Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway

Cell Death and Differentiation

Volumn 16, Issue 6, 2009, Pages 899-909

  Liot, G ^a   Bossy, B ^a,b   Lubitz, S ^b   Kushnareva, Y ^a   Sejbuk, N ^a   Bossy Wetzel, E ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROPROPIONIC ACID; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL FUNCTION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EXCITOTOXICITY; FLUORESCENCE MICROSCOPY; HUNTINGTON CHOREA; MITOCHONDRIAL RESPIRATION; NERVE CELL NECROSIS; NEUROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; APOPTOSIS; CELLS, CULTURED; ELECTRON TRANSPORT COMPLEX II; MITOCHONDRIA; NEURONS; NITRIC OXIDE; NITRO COMPOUNDS; PROPIONIC ACIDS; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 67349120572     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.22     Document Type: Article

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