Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism: A novel regulatory mechanism altered in obesity

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 17190-17197

  Bach, Daniel ^a   Pich, Sara ^a   Soriano, Francesc X ^a   Vega, Nathalie ^b   Baumgartner, Bernhard ^a   Oriola, Josep ^c   Daugaard, Jens R ^a   Lloberas, Jorge ^a   Camps, Marta ^a   Zierath, Juleen R ^d   Rabasa Lhoret, Rémi ^b   Wallberg Henriksson, Harriet ^d   Laville, Martine ^b   Palacín, Manuel ^a   Vidal, Hubert ^b   Rivera, Francisca ^c   Brand, Martin ^e   Zorzano, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSERM   (France)

^c HOSPITAL CLÍNIC   (Spain)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; MUSCLE; OXIDATION; PROTEINS;

OBESITY;

METABOLISM;

COMPLEMENTARY DNA; INSULIN; MEMBRANE PROTEIN; MESSENGER RNA; MFN2 PROTEIN; MITOFUSIN 2; PHOSPHORUS 32; UNCLASSIFIED DRUG; MITOCHONDRIAL PROTEIN; MITOFUSIN 2 PROTEIN, HUMAN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY MASS; CELL RESPIRATION; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; INSULIN BLOOD LEVEL; LEG MUSCLE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MUSCLE DEVELOPMENT; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OBESITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SKELETAL MUSCLE; ANIMAL; CELL MEMBRANE POTENTIAL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MIDDLE AGED; MUSCLE MITOCHONDRION; PATHOLOGY; ULTRASTRUCTURE; ZUCKER RAT;

ANIMALIA; MAMMALIA;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MIDDLE AGED; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; OBESITY; RATS; RATS, ZUCKER;

EID: 0037593949     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212754200     Document Type: Article

References (52)

1. Bakeeva, L. E., Chentsov, Yu. S., and Skulachev, V. P. (1978) Biochim. Biophys. Acta 501, 349-369
2. Kirkwood, S. P., Munn, E. A., and Brooks, G. A. (1986) Am. J Physiol. 251, C395-C402
3. Amchenkova, A. A., Bakeeva, L. E., Chentsov, Y. S., Skulachev, V. P., and Zorov, D. B. (1988) J. Cell Biol. 107, 481-495
4. Skulachev, V. P. (2001) Trends Biochem. Sci. 26, 23-29
5. Nunnari, J., Marshall, W. F., Straight, A., Murray, A., Sedat, J. W., and Walter, P. (1997) Mol. Biol. Cell 8, 1233-1242
6. Suelmann, R., and Fischer, R. (2000) Cell Motil. Cytoskelet. 45, 42-50
7. Collins, T. J., Berridge, M. J., Lipp, P., and Bootman, M. D. (2002) EMBO J. 21, 1616-1627
8. Jensen, R. E., Aiken Hobbs, A. E., Cerveny, K. L., and Sesaki, H. (2000) Micros. Res. Tec. 51, 573-583
9. Shaw, J. M., and Nunnari, J. (2002) Trends Cell Biol. 12, 178-184
10. Hales, K. G., and Fuller, M. T. (1997) Cell 90, 121-129
11. Rapaport, D., Brunner, M., Neupert, W., and Westermann, B. (1998) J. Biol. Chem. 273, 20150-20155
12. Otsuga, D., Keegan, B. R., Brisch, E., Thatcher, J. W., Hermann, G. J., Bleazard, W., and Shaw, J. M. (1998) J. Cell Biol. 143, 333-349
13. Guan, K., Farh, L., Marshall, T. K., and Deschenes, R. J. (1993) Curr. Genet. 24, 141-148
14. Shepard, K, and Yaffe, M. (1999) J. Cell Biol. 144, 711-719
15. Wong, E. D., Wagner, J. A., Gorsich, S. W., McCaffery, J. M., Shaw, J. M., and Nunnari, J. (2000) J. Cell Biol. 151, 341-352
16. Mozdy, A. D., McCaffery, J. M., and Shaw, J. M. (2000) J. Cell Biol. 151, 367-379
17. Tieu, Q., and Nunnart, J. (2000) J. Cell Biol. 151, 353-365
18. Fekkes, P., Shepard, K. A., and Yaffe, M. P. (2000) J. Cell Biol. 151, 333-340
19. Smirnova, E., Shurland, D. L., Ryazantsev, S. N., and van der Bliek, A. M. (1998) J. Cell Biol. 143, 351-358
20. Delettre, C., Lenaers, G., Griffoin, J. M., Gigarel, N., Lorenzo, C., Belenguer, P., Pelloquin, L., Grosgeorge, J., Turc-Carel, C., Perret, E., Astarie-Dequeker, C., Lasquellec, L., Arnaud, B., Ducommun, B., Kaplan, J., and Hamel, C. P. (2000) Nat. Genet. 26, 207-210
21. Alexander, C., Votruba, M., Pesch, U. E., Thiselton, D. L., Mayer, S., Moore, A., Rodriguez, M., Kellner, U., Leo-Kottler, B., Auburger, G., Bhattacharya, S. S., and Wissinger, B. (2000) Nat. Genet. 26, 211-215
22. Santel, A., and Fuller, M. T. (2001) J. Cell Sci. 114, 867-874
23. Bereiter-Hahn, J. (1990) Int. Rev. Cytol. 122, 1-63
24. Mora, S., Monden, I., Zorzano, A., and Keller, K. (1997) Biochem. J 324, 455-459
25. Castello, A., Rodriguez-Manzaneque, J. C., Camps, M., Perez-Castillo, A., Testar, X., Palacin, M., Santos, A., and Zorzano, A. (1994) J. Biol. Chem. 269, 5905-5912
26. Auboeuf, D., and Vidal, H. (1997) Anal. Biochem. 245, 141-148
27. Andreelli, F., Laville, M., Ducluzeau, P. H., Vega, N., Vallier, P., Khalfallah, Y., Riou, J. P., and Vidal, H. (1999) Diabetologia 42, 358-364
28. Di Lisa, F., Blank, P. S., Colonna, R., Gambassi, G., Silverman, H. S., Stern, M. D., and Hansford, R. G. (1995) J. Physiol. (Lond.) 486, 1-13
29. Damdimopoulos, A. E., Miranda-Vizuete, A., Pelto-Huikko, M., Gustafsson, J. A., and Spyrou, G. (2002) J. Biol. Chem. 277, 33249-33257
30. Baddeley, A. J., Gundersen, H. J. G., and Cruz-Orive, L. M. (1986) J. Microsc. (Oxf.) 142, 259-276
31. Santalucia, T., Boheler, K. R., Brand, N. J., Sahye, U., Fandos, C., Vinals, F., Ferre, J., Testar, X., Palacin, M., and Zorzano, A. (1999) J. Biol. Chem. 274, 17626-17634
32. Bett, A. J., Haddara, W., Prevec, L., and Graham, F. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8802
33. Auestad, N., Korsak, R. A., Morrow, J. W., and Edmond, J. (1991) J. Neurochem. 56, 1376-1386
34. Rojo M., Legros F., Chateau D., and Lombes A. (2002) J. Cell Sci. 115, 1663-1674
35. Canicio, J., Gallardo, E., Illa, I., Testar, X., Palacin, M., Zorzano, A., and Kaliman, P. (1998) Endocrinology 139, 5042-5049
36. Astrup, A., Andersen, T., Henriksen, O., Christensen, N. J., Bulow, J., Madsen, J., and Quaade, F. (1987) Int. J. Obesity 11, 51-66
37. Kelley, D. E., and Mandarino, L. J. (2000) Diabetes 49, 677-683
38. Cuendet, G. S., Loten, E. G., Jeanrenaud, B., and Renold, A. E. (1976) J. Clin. Invest. 58, 1078-1088
39. Kemmer, F. W., Berger, M., Herberg, L., Gries, F. A., Wirdeier, A., and Becker, K. (1979) Biochem. J. 178, 733-741
40. Crettaz, M., Prentki, M., Zaninetti, D., and Jeanrenaud, B. (1980) Biochem. J 186, 525-534
41. Kaplan, M. L., and Oh, S. S. (1991) Int. J. Obesity 15, 809-812
42. Turcotte, L. P., Swenberger, J. R., Zavitz Tucker, M., and Yee, A. J. (2001) Diabetes 50, 1389-1396
43. Zorzano, A., Tomàs, E., Camps, M., Gumà, A., and Palacín, M. (2002) in Muscle Metabolism (Zierath, J. R., and Wallberg-Henriksson, H., eds) pp. 297-312, Taylor and Francis, London
44. Wardlaw, G. M., Kaplan, M. L., and Lanza-Jacoby, S. (1986) J. Nutr. 116, 1841-1852
45. Torgan, C. E., Brozinick J. T. Jr., Kastello, G. M., and Ivy, J. L. (1989) J. Appl. Physiol. 67, 1807-1813
46. Amessou, M., Fouque, F., Soussi, N., Desbuquois, B., Hainaut, I., Girard, J., and Benelli, C. (1998) Mol. Cell. Endocrinol. 144, 139-147
47. Kelley, D. E., He, J., Menshikova, E. V., and Ritov, V. B. (2002) Diabetes 51, 2944-2950
48. Simoneau, J. A., Kelley, D. E., Neverova, M., and Warden, C. H. (1998) FASEB J. 12, 1739-1745
49. Phillips, M. S., Liu, Q., Hammond, H. A., Dugan, V., Hey, P. J., Caskey, C. J., and Hess, J. F. (1996) Nat. Genet. 13, 18-19
50. Buchberger, P., and Schmidt, I. (1996) Am. J. Physiol. 271, R472-R476
51. Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., Fei, H., Kim, S., Lallone, R., Ranganathan, S., Kern, P., and Friedman, J. M. (1995)Nat. Med. 1, 1155-1161
52. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayasi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, N., and Nomura, N. (1996) DNA Res. 3, 321-329