Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death

Journal of Biological Chemistry

Volumn 282, Issue 33, 2007, Pages 23788-23798

  Jahani Asl, Arezu ^a   Cheung, Eric C C ^a   Neuspiel, Margaret ^b   MacLaurin, Jason G ^a   Fortin, Andre ^a   Park, David S ^a   McBride, Heidi M ^b   Slack, Ruth S ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHARCOT MARIE TOOTH NEUROPATHY; GRANULE NEURONS; NEURONAL INJURY;

DNA; MEDICAL PROBLEMS; NEURONS; OXIDATIVE STRESS;

CELL DEATH;

MEMBRANE PROTEIN; PROTEIN MITOFUSIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; HEREDITARY MOTOR SENSORY NEUROPATHY; INJURY; MITOCHONDRION; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CELL DEATH; CELL LINE; CEREBELLUM; CHARCOT-MARIE-TOOTH DISEASE; DNA DAMAGE; HUMANS; MEMBRANE FUSION; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEURONS; OXIDATIVE STRESS; TRANSFECTION;

EID: 34548274600     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703812200     Document Type: Article

References (35)

1. Frank, S., Gaume, B., Bergmann-Leitner, E. S., Leitner, W. W., Robert, E. G., Catez, F., Smith, C. L., and Youle, R. J. (2001) Dev. Cell 1, 515-525
2. Lee, Y. J., Jeong, S. Y., Karbowski, M., Smith, C. L., and Youle, R. J. (2004) Mol. Biol. Cell 15, 5001-5011
3. Delivani, P., Adrain, C., Taylor, R. C., Duriez, P. J., and Martin, S. J. (2006) Mol. Cell 21, 761-773
4. Karbowski, M., Arnoult, D., Chen, H., Chan, D. C., Smith, C. L., and Youle, R. J. (2004) J. Cell Biol. 164, 493-499
5. Estaquier, J., and Arnoult, D. (2007) Cell Death Differ. 14, 1086-1094
6. Parone, P. A., James, D. I., Da Cruz, S., Mattenberger, Y., Donze, O., Barja, F., and Martinou, J. C. (2006) Mol. Cell Biol. 26, 7397-7408
7. Shaw, J. M., and Nunnari, J. (2002) Trends Cell Biol. 12, 178-184
8. Chen, H., Detmer, S. A., Ewald, A. J., Griffin, E. E., Fraser, S. E., and Chan, D. C. (2003) J. Cell Biol. 160, 189-200
9. Detmer, S. A., and Chan, D. C. (2007) J. Cell Biol. 176, 405-414
10. Ishihara, N., Eura, Y., and Mihara, K. (2004) J. Cell Sci. 117, 6535-6546
11. Eura, Y., Ishihara, N., Yokota, S., and Mihara, K. (2003) J. Biochem. (Tokyo) 134, 333-344
12. Cipolat, S., Martins de Brito, O., Dal Zilio, B., and Scorrano, L. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 15927-15932
13. Karbowski, M., Lee, Y. J., Gaume, B., Jeong, S. Y., Frank, S., Nechushtan, A., Santel, A., Fuller, M., Smith, C. L., and Youle, R. J. (2002) J. Cell Biol. 159, 931-938
14. Bach, D., Pich, S., Soriano, F. X., Vega, N., Baumgartner, B., Oriola, J., Daugaard, J. R., Lloberas, J., Camps, M., Zierath, J. R., Rabasa-Lhoret, R., Wallberg-Henriksson, H., Laville, M., Palacin, M., Vidal, H., Rivera, F., Brand, M., and Zorzano, A. (2003) J. Biol. Chem. 278, 17190-17197
15. Pich, S., Bach, D., Briones, P., Liesa, M., Camps, M., Testar, X., Palacin, M., and Zorzano, A. (2005) Hum. Mol. Genet. 14, 1405-1415
16. Karbowski, M., Norris, K. L., Cleland, M. M., Jeong, S. Y., and Youle, R. J. (2006) Nature 443, 658-662
17. Zuchner, S., Mersiyanova, I. V., Muglia, M., Bissar-Tadmouri, N., Rochelle, J., Dadali, E. L., Zappia, M., Nelis, E., Patitucci, A., Senderek, J., Parman, Y., Evgrafov, O., Jonghe, P. D., Takahashi, Y., Tsuji, S., Pericak-Vance, M. A., Quattrone, A., Battologlu, E., Polyakov, A. V., Timmerman, V., Schroder, J. M., and Vance, J. M. (2004) Nat. Genet. 36, 449-451
18. Neuspiel, M., Zunino, R., Gangaraju, S., Rippstein, P., and McBride, H. M. (2005) J. Biol. Chem. 280, 25060-25070
19. Fortin, A., Cregan, S. P., MacLaurin, J. G., Kushwaha, N., Hickman, E. S., Thompson, C. S., Hakim, A., Albert, P. R., Cecconi, F., Helin, K., Park, D. S., and Slack, R. S. (2001) J. Cell Biol. 155, 207-216
20. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W., and Vogelstein, B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2509-2514
21. Cregan, S. P., Fortin, A., MacLaurin, J. G., Callaghan, S. M., Cecconi, F., Yu, S. W., Dawson, T. M., Dawson, V. L., Park, D. S., Kroemer, G., and Slack, R. S. (2002) J. Cell Biol. 158, 507-517
22. Goping, I. S., Millar, D. G., and Shore, G. C. (1995) FEBS Lett. 373, 45-50
23. Rintoul, G. L., Filiano, A. J., Brocard, J. B., Kress, G. J., and Reynolds, I. J. (2003) J. Neurosci. 23, 7881-7888
24. McGahan, L., Hakim, A. M., and Robertson, G. S. (1998) Brain Res. Mol. Brain Res. 56, 133-145
25. Harder, Z., Zunino, R., and McBride, H. (2004) Curr. Biol. 14, 340-345
26. Cole, K., and Perez-Polo, J. R. (2004) Int. J. Dev. Neurosci. 22, 485-496
27. Scorrano, L., and Korsmeyer, S. J. (2003) Biochem. Biophys. Res. Commun. 304, 437-444
28. Germain, M., Mathai, J. P., McBride, H. M., and Shore, G. C. (2005)EMBO J. 24, 1546-1556
29. Yuan, F., Wang, T., Luo, L., Sun, Y., Zhang, L., and Qu, B. (2000) Chin. Med. J. (Engl.) 113, 728-732
30. Yuan, Q., Xie, Y., So, K. F., and Wu, W. (2003) Dev. Neurosci. 25, 72-78
31. Harris, C., Maroney, A. C., and Johnson, E. M., Jr. (2002) J. Neurochem. 83, 992-1001
32. Jekabsons, M. B., and Nicholls, D. G. (2006) Cell Death Differ. 13, 1595-1610
33. Piccioli, P., Porcile, C., Stanzione, S., Bisaglia, M., Bajetto, A., Bonavia, R., Florio, T., and Schettini, G. (2001) J. Neurosci. Res. 66, 1064-1073
34. Barsoum, M. J., Yuan, H., Gerencser, A. A., Liot, G., Kushnareva, Y., Graber, S., Kovacs, I., Lee, W. D., Waggoner, J., Cui, J., White, A. D., Bossy, B., Martinou, J. C., Youle, R. J., Lipton, S. A., Ellisman, M. H., Perkins, G. A., and Bossy-Wetzel, E. (2006) EMBO J. 25, 3900-3911
35. Chen, H., Chomyn, A., and Chan, D. C. (2005) J. Biol. Chem. 280, 26185-26192